Yuan Geng

author keywords: adaptive LASSO; censored regression; mean survival time; optimal treatment regime; variable selection

MeSH headings : Acquired Immunodeficiency Syndrome / drug therapy; Acquired Immunodeficiency Syndrome / mortality; Anti-HIV Agents / administration & dosage; Biostatistics / methods; Clinical Trials as Topic / statistics & numerical data; Computer Simulation; Humans; Kaplan-Meier Estimate; Least-Squares Analysis; Models, Statistical; Precision Medicine / methods; Precision Medicine / statistics & numerical data; Regression Analysis; Statistics, Nonparametric; Survival Rate

TL;DR: This paper proposes a robust loss‐based estimation framework that can be easily coupled with shrinkage penalties for both estimation of optimal treatment regimes and variable selection, and a model‐free estimator of restricted mean survival time under the derived optimal treatment regime is developed. (via Semantic Scholar)