Works (4)

Updated: July 5th, 2023 15:30

2023 journal article

Duration of exposure to epidural anesthesia at delivery, DNA methylation in umbilical cord blood and their association with offspring asthma in Non-Hispanic Black women


By: Y. Wang n, J. Tzeng n, Y. Huang n, R. Maguire n, C. Hoyo n & T. Allen*

author keywords: epidural anesthesia; labor analgesia; asthma; health disparities; DNA methylation; mediation analysis
TL;DR: It is suggested that DNA methylation in immune-related pathways contributes to the effects of the duration of exposure to epidural anesthesia on childhood asthma risk in NHB offspring. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: February 13, 2023

2021 journal article

Gene-set integrative analysis of multi-omics data using tensor-based association test

BIOINFORMATICS, 37(16), 2259–2265.

By: S. Chang*, M. Yang n, W. Lu n, Y. Huang*, Y. Huang n, H. Hung*, J. Miecznikowski*, T. Lu*, J. Tzeng n

TL;DR: A tensor-based framework for variable-wise inference in multi-omics analysis is introduced and the variable-specific tensor test is derived, which will enhance computational efficiency of tensor modeling. (via Semantic Scholar)
Source: Web Of Science
Added: October 18, 2021

2020 journal article

The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort


By: Y. Huang n, J. Tzeng n, R. Maguire n, C. Hoyo n & T. Allen*

author keywords: Anesthesia; opioid analgesics; asthma; children; sex-specific
MeSH headings : Adult; Anesthesia, Epidural / adverse effects; Anesthesia, Obstetrical / adverse effects; Asthma / etiology; Cesarean Section / adverse effects; Child; Child, Preschool; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Logistic Models; Male; Pregnancy; Retrospective Studies
TL;DR: The data suggest that peripartum exposure to neuraxial anesthesia may reduce the risk of childhood asthma primarily in males. (via Semantic Scholar)
Source: Web Of Science
Added: June 22, 2020

2019 journal article

A Small-Molecule Inhibitor of trans-Translation Synergistically Interacts with Cathelicidin Antimicrobial Peptides To Impair Survival of Staphylococcus aureus


By: Y. Huang*, J. Alumasa*, L. Callaghan*, R. Baugh*, C. Rae*, K. Keiler*, S. McGillivray*

author keywords: LL-37; Staphylococcus aureus; trans-translation; cathelicidin; oxadiazoles
MeSH headings : Anti-Bacterial Agents / pharmacology; Antimicrobial Cationic Peptides / pharmacology; Cell Line, Tumor; Drug Synergism; HeLa Cells; Humans; Methicillin Resistance / drug effects; Microbial Sensitivity Tests; Small Molecule Libraries / pharmacology; Staphylococcal Infections / drug therapy; Staphylococcal Infections / microbiology; Staphylococcus aureus / drug effects; Cathelicidins
TL;DR: The potential of KKL-40, a small-molecule inhibitor of trans-translation, is investigated, and it is found that it inhibits both methicillin-susceptible and methiillin-resistant strains of S. aureus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 9, 2019

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