Ying H. Wang

Works (10)

Updated: April 25th, 2025 12:48

2013 journal article

A Transgenerational Endocrine Signaling Pathway in Crustacea

PLoS ONE, 8(4), e61715.

By: G. LeBlanc n , Y. Wang n, C. Holmes n, G. Kwon n & E. Medlock n

Ed(s): B. He n

MeSH headings : Amino Acid Sequence; Animals; Cloning, Molecular; Crustacea / drug effects; Crustacea / metabolism; Daphnia / drug effects; Daphnia / physiology; Endocrine System / drug effects; Endocrine System / metabolism; Fatty Acids, Unsaturated / pharmacology; Female; Fertility; Genes, Reporter; Life Cycle Stages / drug effects; Ligands; Luciferases / metabolism; Male; Molecular Sequence Data; Population Density; Pyridines / pharmacology; Sex Determination Processes / drug effects; Sex Ratio; Signal Transduction / drug effects; Transcription Factors / chemistry
topics (OpenAlex): Neurobiology and Insect Physiology Research; Environmental Toxicology and Ecotoxicology; Insect Resistance and Genetics
TL;DR: Results reveal likely components to a hormone/receptor signaling pathway in a crustacean that orchestrates transgenerational modifications to important population metrics (sex ratios, fecundity of females) and how these signaling processes can facilitate population sustainability under normal conditions or threaten sustainability when perturbed by environmental chemicals. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 article

Tributyltin Synergizes with 20-Hydroxyecdysone to Produce Endocrine Toxicity

Wang, Y. H., Kwon, G., Li, H., & LeBlanc, G. A. (2011, June 14). Toxicological Sciences, Vol. 123, pp. 71–79.

By: Y. Wang n, G. Kwon n, H. Li n & G. LeBlanc n 

author keywords: chemical mixtures; models; synergy; invertebrate; ecdysteroid; nuclear receptor; retinoid X receptor; ecdysteroid receptor
MeSH headings : Animals; Cells, Cultured; Daphnia; Dose-Response Relationship, Drug; Drug Synergism; Ecdysterone / metabolism; Ecdysterone / toxicity; Female; Gene Expression / drug effects; Molting / drug effects; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Retinoid X Receptors / genetics; Retinoid X Receptors / metabolism; Signal Transduction; Trialkyltin Compounds / toxicity; Water Pollutants, Chemical / toxicity
topics (OpenAlex): Marine Biology and Environmental Chemistry; Environmental Toxicology and Ecotoxicology; Retinoids in leukemia and cellular processes
TL;DR: Results demonstrate that xenobiotics, such as tributyltin, can interact with RXR to influence gene expression regulated by the heterodimeric partner to RXR. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 article

Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription

Hannas, B. R., Wang, Y. H., Baldwin, W. S., Li, Y., Wallace, A. D., & LeBlanc, G. A. (2010, March 25). General and Comparative Endocrinology, Vol. 167, pp. 268–278.

By: B. Hannas n, Y. Wang n, W. Baldwin *, Y. Li *, A. Wallace n & G. LeBlanc n 

author keywords: Daphnia pulex; Ecdysteroids; Endocrine disruptor; Nuclear receptors
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Daphnia / genetics; Daphnia / metabolism; Electrophoretic Mobility Shift Assay; Female; Gene Expression Regulation; Immunoblotting; Molecular Sequence Data; Phylogeny; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Receptors, Cytoplasmic and Nuclear / biosynthesis; Receptors, Cytoplasmic and Nuclear / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Signal Transduction; Transfection
topics (OpenAlex): Neurobiology and Insect Physiology Research; Retinal Development and Disorders; Cellular transport and secretion
TL;DR: The premise that HR3 is a major component of ecdysteroid signaling in some crustaceans and is under the negative regulatory control of E75 is supported. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 article

Regulation and dysregulation of vitellogenin mRNA accumulation in daphnids (Daphnia magna)

Hannas, B. R., Wang, Y. H., Thomson, S., Kwon, G., Li, H., & LeBlanc, G. A. (2010, November 20). Aquatic Toxicology, Vol. 101, pp. 351–357.

By: B. Hannas n, Y. Wang n, S. Thomson n, G. Kwon n, H. Li n & G. LeBlanc n 

author keywords: Vitellogenin; Water flea; Biomarker; Ecdysteroids; Estrogens; Endocrine disruption
MeSH headings : Animals; Cadmium / toxicity; Daphnia / drug effects; Daphnia / genetics; Daphnia / metabolism; Ecdysteroids / toxicity; Ecdysterone / toxicity; Environmental Pollutants / toxicity; Estrogens / toxicity; Gene Expression / drug effects; Heterocyclic Compounds / toxicity; Polycyclic Compounds / toxicity; RNA, Messenger / metabolism; Vitellogenins / genetics; Vitellogenins / metabolism; Xenobiotics / toxicity
topics (OpenAlex): Neurobiology and Insect Physiology Research; Environmental Toxicology and Ecotoxicology; Reproductive biology and impacts on aquatic species
TL;DR: Results indicate that ecdysteroids are suppressors of vitellogenin gene expression and that viteLLogenin mRNA levels can be elevated or suppressed in daphnids by xenobiotics that elicit antiecdysteroidal or ecdystersoidal activity, respectively. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Annotation, phylogenetics, and expression of the nuclear receptors in Daphnia pulex

BMC Genomics, 10.

By: S. Thomson, W. Baldwin, Y. Wang, G. Kwon & G. LeBlanc

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Interactions of methyl farnesoate and related compounds with a crustacean retinoid X receptor

Molecular and Cellular Endocrinology, 309(1-2), 109–116.

By: Y. Wang n & G. LeBlanc n 

author keywords: RXR; EcR; Methyl farnesoate; Daphnia; Tributyltin
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; DNA, Complementary / genetics; DNA, Complementary / isolation & purification; Daphnia / drug effects; Daphnia / metabolism; Ecdysterone / pharmacology; Fatty Acids, Unsaturated / metabolism; Genes, Reporter; Humans; Ligands; Luciferases / metabolism; Male; Molecular Sequence Data; Open Reading Frames / genetics; Receptors, Steroid / metabolism; Retinoid X Receptors / chemistry; Retinoid X Receptors / genetics; Retinoid X Receptors / metabolism; Sequence Alignment; Sequence Homology, Amino Acid; Sex Determination Processes; Sex Ratio; Transcriptional Activation / drug effects
topics (OpenAlex): Retinoids in leukemia and cellular processes; Neurobiology and Insect Physiology Research; Antioxidant Activity and Oxidative Stress
TL;DR: Results indicate that methyl farnesoate, along with compounds that are functionally similar to methyl farNESoate synergize with ecdysteroids to activate the RXR:EcR receptor complex, however, this effect appears to be unrelated to the ability of these compounds to stimulate male sex determination. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2008 journal article

A new tunnel function method for global optimization

Pacific Journal of Optimization, 4(1), 125–138.

By: L. Zhang, S. Fang  & Y. Wang

Source: NC State University Libraries
Added: August 6, 2018

2006 article

Cloning and characterization of the retinoid X receptor from a primitive crustacean Daphnia magna

Wang, Y. H., Wang, G., & LeBlanc, G. A. (2006, September 27). General and Comparative Endocrinology, Vol. 150, pp. 309–318.

By: Y. Wang n, G. Wang n & G. LeBlanc n 

author keywords: crustacean; Daphnia; RXR; hormone; receptor; endocrine; sex determination
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary / genetics; Daphnia / genetics; Daphnia / metabolism; Ecdysterone / pharmacology; Fatty Acids, Unsaturated / metabolism; Female; Gene Expression Regulation, Developmental / drug effects; Male; Molecular Sequence Data; Phylogeny; Pyridines / pharmacology; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Retinoid X Receptors / antagonists & inhibitors; Retinoid X Receptors / biosynthesis; Retinoid X Receptors / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment
topics (OpenAlex): Retinoids in leukemia and cellular processes; Antioxidant Activity and Oxidative Stress; Neurobiology and Insect Physiology Research
TL;DR: Results show that branchiopod crustaceans dynamically express RXR which should be evaluated as a candidate receptor for the terpenoid hormone methyl farnesoate which functions as a sex determinant in these organisms. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

CpG + CpNpG Analysis of Protein-Coding Sequences from Tomato

Hobolth, A. (2006, March 13). Molecular Biology and Evolution.

By: A. Hobolth n

author keywords: codon model; context dependency; CpG plus CpNpG methylation
MeSH headings : Base Composition; CpG Islands / genetics; DNA Methylation; Genes, Plant; Solanum lycopersicum / genetics; Models, Genetic; Mutation
topics (OpenAlex): RNA and protein synthesis mechanisms; Genomics and Phylogenetic Studies; Genomics and Chromatin Dynamics
TL;DR: The results suggest different roles of CpG and CpNpG methylation, with Cp npG possibly playing a specialized role in defense against transposons and RNA viruses. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 journal article

The role of polyampholyte charge density on its interactions with cellulose

Nordic Pulp & Paper Research Journal, 21(5), 158–165.

By: Y. Wang, M. Hubbe, T. Sezaki, X. Wang, O. Rojas & D. Argyropoulos 

Source: NC State University Libraries
Added: August 6, 2018

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