Works (50)

Updated: May 15th, 2024 04:43

2024 journal article

Multiscale imaging of corneal endothelium damage and Rho-kinase inhibitor application in mouse models of acute ocular hypertension

BIOMEDICAL OPTICS EXPRESS, 15(2).

By: Z. Cai*, Y. Zhang n, R. Fang, B. Brenner, J. Kweon, C. Sun, J. Goldberg*, H. Zhang

Sources: Web Of Science, NC State University Libraries
Added: April 22, 2024

2024 journal article

Quantifying nanoscopic alterations associated with mitochondrial dysfunction using three-dimensional single-molecule localization microscopy

BIOMEDICAL OPTICS EXPRESS, 15(3), 1571–1584.

By: B. Brenner*, F. Xu*, Y. Zhang n, J. Kweon*, R. Fang*, N. Sheibani*, S. Zhang*, C. Sun*, H. Zhang*

Sources: Web Of Science, NC State University Libraries
Added: May 7, 2024

2023 article

Integrating Machine Learning and Color Chemistry: Developing a High-School Curriculum toward Real-World Problem-Solving

Jiang, S., Mcclure, J., Mao, H., Chen, J., Liu, Y., & Zhang, Y. (2023, December 7). JOURNAL OF CHEMICAL EDUCATION, Vol. 12.

By: S. Jiang n, J. Mcclure n, H. Mao n, J. Chen n, Y. Liu n & Y. Zhang n

author keywords: Machine Learning; High School; Analytical Chemistry; pH Test; Colorimetric Analysis; Interdisciplinarity
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 1, 2024

2023 article

Investigating Uncertainties in Single-Molecule Localization Microscopy Using Experimentally Informed Monte Carlo Simulation

Yeo, W.-H., Zhang, Y., Neely, A. E., Bao, X., Sun, C., & Zhang, H. F. (2023, July 18). NANO LETTERS, Vol. 7.

By: W. Yeo*, Y. Zhang n, A. Neely*, X. Bao*, C. Sun* & H. Zhang*

author keywords: Single-molecule localization microscopy; Monte Carlosimulation; nuclear pore complex; image processing
TL;DR: A Monte Carlo (MC) simulation based on experimental imaging parameters and geometric information is developed to generate synthetic SMLM images and illustrated using the MC model to generate cellular substructures with different angles of labeling to inform the structural understanding of the images obtained. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 7, 2023

2023 journal article

Nucleoporin downregulation modulates progenitor differentiation independent of nuclear pore numbers

COMMUNICATIONS BIOLOGY, 6(1).

By: A. Neely*, Y. Zhang n, L. Blumensaadt*, H. Mao n, B. Brenner*, C. Sun*, H. Zhang*, X. Bao*

TL;DR: It is identified that NUP93 knockdown induces differentiation genes related to both mechanical and immune barrier functions, including the activation of known NF-κB target genes, including the activation of known NF-κB target genes. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 18, 2023

2023 review

Photoactivatable BODIPYs for Live-Cell PALM

[Review of ]. MOLECULES, 28(6).

author keywords: borondipyrromethenes (BODIPYs); fluorescence imaging; photoactivatable fluorophores (PAFs); photoactivated localization microscopy (PALM); single-molecule localization microscopy (SMLM)
MeSH headings : Microscopy, Fluorescence / methods; Boron Compounds / chemistry; Fluorescent Dyes / chemistry
TL;DR: This work has shown that photoactivatable BODIPYs have already allowed the sub-diffraction imaging of diverse cellular substructures in live cells using PALM and can evolve into invaluable analytical probes for bioimaging applications. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 17, 2023

2023 journal article

Photoactivatable Fluorophores for Bioimaging Applications

ACS Applied Optical Materials, 1(3), 640–651.

Source: ORCID
Added: February 1, 2024

2023 article

Photoactivatable fluorophores for bioimaging applications

COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XVIII, Vol. 12395.

By: Y. Zhang n, Y. Zheng*, A. Tomassini*, C. Hayter* & F. Raymo*

author keywords: BODIPYs; fluorescence imaging; PALM; photoactivatable fluorophores; photocages; SMLM; singlemolecule; tracking; super-resolution imaging
TL;DR: A new family of synthetic photoactivatable fluorophores specifically designed for single-molecule localization microscopy, which combine a borondipyrromethene (BODIPY) fluorophore and an ortho-nitrobenzyl (ONB) photocage in a single molecular skeleton. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023

2023 journal article

Spectral precision improvement with demagnifying spectral images in spectroscopic nanoscopy

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 41(1), 39–44.

By: K. Song* & Y. Zhang n

Sources: Web Of Science, NC State University Libraries
Added: May 7, 2024

2023 journal article

Switchable and Functional Fluorophores for Multidimensional Single-Molecule Localization Microscopy

Chemical & Biomedical Imaging.

By: Y. Liu n, M. Shahid n, H. Mao n, J. Chen n, M. Waddington n, K. Song*, Y. Zhang n

Source: ORCID
Added: February 1, 2024

2023 article

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

Chen, J., Tang, X., Wang, Z., Perez, A., Yao, B., Huang, K., … King, M. W. W. (2023, June 26). BIOENGINEERING & TRANSLATIONAL MEDICINE, Vol. 6.

By: J. Chen n, X. Tang n, Z. Wang n, A. Perez*, B. Yao*, K. Huang n, Y. Zhang n, M. King n

author keywords: abdominal adhesion; adhesion prevention; anti-adhesion strategy; anti-inflammatory; fibrinolytic agent; physical barrier; postsurgical adhesion
TL;DR: Anti‐adhesion agents represent a promising approach for reducing the burden of adhesion‐related complications in surgical patients and further research is needed to optimize their use and develop new therapies for this challenging clinical problem. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 24, 2023

2022 article

Experimental Parameters-Based Monte-Carlo Simulation of Single-Molecule Localization Microscopy of Nuclear Pore Complex to Evaluate Clustering Algorithms

Yeo, W.-H., Zhang, Y., Neely, A. E., Bao, X., Sun, C., & Zhang, H. F. (2022, September 22).

By: W. Yeo*, Y. Zhang n, A. Neely*, X. Bao*, C. Sun* & H. Zhang*

TL;DR: A Monte-Carlo simulation was developed to generate synthetic SMLM images of NPC and the simulated NPC images were used as the ground truth to evaluate the performance of six clustering algorithms and identified HDBSCAN as the optimal clustering algorithm for NPC counting and sizing. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2022 journal article

Minimizing Molecular Misidentification in Imaging Low-Abundance Protein Interactions Using Spectroscopic Single-Molecule Localization Microscopy

Analytical Chemistry.

MeSH headings : Biological Phenomena; Fluorescent Dyes / chemistry; Microscopy, Fluorescence / methods; Single Molecule Imaging / methods; Staurosporine / pharmacology
TL;DR: A deep learning-based imaging analysis method for spectroscopic single-molecule localization microscopy to minimize molecular misidentification in three-color super-resolution imaging is developed. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2021 journal article

Investigating Single-Molecule Fluorescence Spectral Heterogeneity of Rhodamines Using High-Throughput Single-Molecule Spectroscopy

The Journal of Physical Chemistry Letters, 12(16), 3914–3921.

MeSH headings : Fluorescence; Fluorescent Dyes / chemistry; Molecular Conformation; Rhodamines / chemistry; Rotation; Single Molecule Imaging / methods
TL;DR: It is found that the rotational flexibility of N,N-dialkylated groups contributed to the smFSH, and the system's noise uncertainty, single-molecule spectral diffusion, and environmental polarity were ruled out. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2020 journal article

Accelerating multicolor spectroscopic single-molecule localization microscopy using deep learning

Biomedical Optics Express.

TL;DR: This method uses deep convolution neural networks to reconstruct high-density multicolor super-resolution images from low-density, contaminated multicolors rendered using sSMLM datasets with much fewer frames, without compromising spatial resolution. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2020 journal article

Compact, “Clickable” Quantum Dots Photoligated with Multifunctional Zwitterionic Polymers for Immunofluorescence and In Vivo Imaging

Bioconjugate Chemistry, 31(5), 1497–1509.

MeSH headings : Animals; Azides / chemistry; Cell Line; Click Chemistry; Drosophila melanogaster / embryology; Fluorescent Antibody Technique; Fluorescent Dyes / chemistry; Imidazoles / chemistry; Ligands; Neurons / cytology; Optical Imaging / methods; Particle Size; Polymers / chemistry; Quantum Dots / chemistry; Signal Transduction; Sulfhydryl Compounds / chemistry
TL;DR: The preparation of highly fluorescent quantum dots, surface-engineered with multifunctional polymer ligands that are compact, readily compatible with strain-promoted click conjugation, and the use of these nanocrystals in immunofluorescence and in-vivo imaging are detailed. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2020 journal article

Live-Cell Imaging at the Nanoscale with Bioconjugatable and Photoactivatable Fluorophores

Bioconjugate Chemistry, 31(4), 1052–1062.

By: Y. Zhang* & F. Raymo*

MeSH headings : Cell Line; Cell Survival; Fluorescent Dyes / chemistry; Fluorescent Dyes / metabolism; Humans; Intracellular Space / metabolism; Light; Molecular Imaging / methods; Nanotechnology / methods
TL;DR: Significant synthetic efforts in conjunction with spectroscopic analyses are still very much needed to advance this promising research area further and turn photoactivatable fluorophores into the imaging probes of choice for the investigation of live cells. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2020 journal article

Photoactivatable fluorophores for single-molecule localization microscopy of live cells

Methods and Applications in Fluorescence, 8(3), 032002.

By: Y. Zhang* & F. Raymo*

MeSH headings : Humans; Microscopy, Fluorescence / methods; Single Molecule Imaging / methods
Source: ORCID
Added: March 13, 2023

2020 journal article

Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction

Langmuir, 36(9), 2291–2299.

MeSH headings : Cluster Analysis; Fluorescent Dyes / chemistry; Liposomes / chemistry; Nanoparticles / chemistry; Oxazines / chemistry; Polymers / chemistry; Single Molecule Imaging / methods; Single Molecule Imaging / statistics & numerical data
TL;DR: The feasibility of using spectroscopic point accumulation for imaging in nanoscale topography to visualize self-assembled polymersomes (PS) with molecular specificity was shown and the unique spectral signatures of Nile Red molecules bound to the PS were analyzed to reject artifacts from non-specific NR bindings. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2019 journal article

High-Throughput Single-Molecule Spectroscopy Resolves the Conformational Isomers of BODIPY Chromophores

The Journal of Physical Chemistry Letters, 10(21), 6807–6812.

TL;DR: Statistical analysis of multiple single-molecule emission spectra can discriminate stereoisomers that would otherwise be impossible to distinguish by ensemble measurements alone. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: ORCID
Added: March 13, 2023

2019 journal article

Machine-learning based spectral classification for spectroscopic single-molecule localization microscopy

Optics Letters.

TL;DR: This work developed a machine learning (ML)-based method to analyze the full spectral profiles of each molecular emission and reduce the misclassification rate, and showed that the ML method achieved 10-fold reduction in mis classification and two-fold improvement in spectral data utilization comparing with the existing spectral centroid method. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2019 journal article

Multicolor super-resolution imaging using spectroscopic single-molecule localization microscopy with optimal spectral dispersion

Applied Optics.

TL;DR: Transmission diffraction grating-based spectroscopic single-molecule localization microscopy (sSMLM) was developed to collect the spatial and spectral information of single-Molecule blinking events concurrently and the spectral heterogeneities of multiple far-red emitting dyes were characterized. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2019 journal article

Three-dimensional biplane spectroscopic single-molecule localization microscopy

Optica.

Source: ORCID
Added: March 13, 2023

2019 journal article

Three-dimensional biplane spectroscopic single-molecule localization microscopy: erratum

Optica.

By: K. Song, Y. Zhang*, G. Wang, C. Sun & H. Zhang

Source: ORCID
Added: March 13, 2023

2018 journal article

A Photoactivatable Far-Red/Near-Infrared BODIPY To Monitor Cellular Dynamics in Vivo

ACS Sensors, 3(7), 1347–1353.

MeSH headings : Animals; Boron Compounds / chemistry; Drosophila melanogaster / embryology; Fluorescent Dyes / chemistry; Infrared Rays; Models, Molecular; Optical Imaging / methods; Oxazines / chemistry; Photolysis; Pyrroles / chemistry
TL;DR: The structural design and operating principles for the photoactivation of far-red/near-infrared fluorescence can evolve into invaluable probes to monitor cellular dynamics in vivo to enable tracking of individual cells within the embryos in real time. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2018 journal article

Far-Red Photoactivatable BODIPYs for the Super-Resolution Imaging of Live Cells

Journal of the American Chemical Society, 140(40), 12741–12745.

By: Y. Zhang*, K. Song*, S. Tang*, L. Ravelo*, J. Cusido*, C. Sun*, H. Zhang*, F. Raymo*

MeSH headings : Animals; Boron Compounds / analysis; COS Cells; Chlorocebus aethiops; Fluorescence; Fluorescent Dyes / analysis; Lysosomes / chemistry; Lysosomes / ultrastructure; Microscopy, Fluorescence / methods; Optical Imaging / methods; Photochemical Processes; Single Molecule Imaging / methods
TL;DR: The combination of photochemical, photophysical and structural properties designed into the fluorophores enable the visualization of live cells with a spatial resolution that is inaccessible to conventional fluorescence imaging. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2018 journal article

Fluorescence activation with switchable oxazines

Chemical Communications.

TL;DR: These mechanisms for fluorescence activation enable the acquisition of images with subdiffraction resolution, the selective signaling of cancer cells and the monitoring of translocating species in real time, and can evolve into invaluable probes for the implementation of bioimaging strategies that would be impossible to perform with conventional fluorophores. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: March 13, 2023

2018 journal article

Photochemical Barcodes

Journal of the American Chemical Society, 140(13), 4485–4488.

By: S. Tang*, Y. Zhang*, P. Dhakal*, L. Ravelo*, C. Anderson*, K. Collins*, F. Raymo*

MeSH headings : Boron Compounds / chemistry; DNA Barcoding, Taxonomic; Light; Oxyquinoline / chemistry
TL;DR: The authors' photochemical strategy for the generation of fluorescence barcodes can produce multiple and distinguishable labels in the same biological sample to enable the spatiotemporal tracking of, otherwise indistinguishable, targets. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2017 journal article

A photoactivatable light tracer

Journal of Materials Chemistry C.

By: X. Liu*, Y. Zhang*, J. Baker* & F. Raymo*

TL;DR: The results suggest that photoactivatable fluorophores can be optimal chemical probes to trace propagating light in microoptics and provide definitive experimental evidence of the light-guiding and light-enhancing capabilities of these particular pyramidal PDMS objects. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2017 journal article

Bioimaging with Macromolecular Probes Incorporating Multiple BODIPY Fluorophores

Bioconjugate Chemistry, 28(5), 1519–1528.

MeSH headings : Animals; Boron Compounds / chemistry; Caenorhabditis elegans / cytology; Caenorhabditis elegans / metabolism; Diagnostic Imaging / methods; Fluorescent Dyes / chemistry; HeLa Cells; Humans; Macromolecular Substances / chemistry; Nanoparticles / chemistry; Polymers / chemistry
TL;DR: The results demonstrate that this particular structural design for the incorporation of multiple chromophores within the same covalent construct is a viable one to preserve the photophysical properties of the emissive species and enable the assembly of bioimaging probes with enhanced brightness. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2017 journal article

Detection of nitroaromatic explosives by a 3D hyperbranched σ–π conjugated polymer based on a POSS scaffold

J. Mater. Chem. A.

Source: ORCID
Added: March 13, 2023

2017 journal article

Facile fabrication of AIE/AIEE-active fluorescent nanoparticles based on barbituric for cell imaging applications

RSC Adv., 7(48), 30229–30241.

Source: ORCID
Added: March 13, 2023

2017 journal article

Fluorescence patterning with mild illumination in polymer films of photocleavable oxazines

J. Mater. Chem. C, 5(5), 1179–1183.

By: E. Thapaliya*, Y. Zhang* & F. Raymo*

Source: ORCID
Added: March 13, 2023

2017 conference paper

Highlighting cancer cells with macromolecular probes

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

By: S. Tang*, Y. Zhang*, E. Thapaliya*, A. Brown*, J. Wilson* & F. Raymo*

Ed(s): M. Osiński, W. Parak & X. Liang

TL;DR: A viable structural design is identified based on the integration of activatable fluorophores and targeting ligands within the same macromolecular construct that translates into a 170-fold enhancement in brightness, relative to equivalent but isolated chromophoric components, and a 3-fold increase in contrast. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2017 conference paper

Probing the intracellular fate of supramolecular nanocarriers and their cargo with FRET schemes

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

Ed(s): M. Osiński, W. Parak & X. Liang

TL;DR: This protocol is particularly valuable to monitor the transport properties of supramolecular nanocarriers inside living cells and can eventually contribute to the fundamental understating of the ability of these promising vehicles to deliver contrast agents and/ or drugs intracellularly in view of possible diagnostics and/or therapeutic applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: March 13, 2023

2017 conference paper

Supramolecular delivery of photoactivatable fluorophores in developing embryos

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

Ed(s): M. Osiński, W. Parak & X. Liang

TL;DR: The supramolecular delivery of photoactivatable fluorophores in Drosophila melanogaster embryos allows the real-time tracking of translocating molecules and translates into a noninvasive method to monitor dynamics in vivo and can evolve into a general chemical tool to track motion in biological specimens. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

A Photoswitchable Fluorophore for the Real-Time Monitoring of Dynamic Events in Living Organisms

Chemistry - A European Journal, 22(42), 15027–15034.

MeSH headings : Animals; Drosophila melanogaster; Fluorescent Dyes / chemistry; Photochemical Processes
TL;DR: The synthesis of a photoactivatable fluorophore with optimal photochemical and photophysical properties for the real-time tracking of motion in vivo can evolve into a general chemical tool to monitor dynamic processes in living biological specimens. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

A pH-Gated Photocage

Advanced Optical Materials, 5.

By: Y. Zhang*, B. Captain* & F. Raymo*

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: March 13, 2023

2016 journal article

Highlighting Cancer Cells with Halochromic Switches

ACS Sensors, 2(1), 92–101.

By: S. Tang*, Y. Zhang*, E. Thapaliya*, A. Brown*, J. Wilson* & F. Raymo*

TL;DR: The structural design for the covalent integration of activatable signaling units and targeting ligands within the same nanostructured assembly together with the photophysical properties engineered into the emissive components offer the opportunity to highlight cancer cells selectively with high brightness and optimal contrast. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 article

Semiconductor Quantum Dots with Photoresponsive Ligands

Sansalone, L., Tang, S., Zhang, Y., Thapaliya, E. R., Raymo, F. M., & Garcia-Amorós, J. (2016, October). Photoactive Semiconductor Nanocrystal Quantum Dots, pp. 31–60.

Source: ORCID
Added: March 13, 2023

2016 journal article

Supramolecular delivery of fluorescent probes in developing embryos

RSC Adv., 6(76), 72756–72760.

TL;DR: Self-assembling nanocarriers of amphiphilic polymers encapsulate hydrophobic fluorophores in their hydrophilic interior and, upon injection in Drosophila melanogaster embryos, release their cargo into the cellular blastoderm. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 conference paper

Supramolecular nanocarriers with photoresponsive cargo

In W. J. Parak, M. Osinski, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XI.

Ed(s): W. Parak, M. Osinski & X. Liang

TL;DR: Operating principles to solubilize and operate photoswitchable fluorophores in aqueous environments with the aid of supramolecular nanocarriers can lead to valuable protocols to image specimens with subdiffraction resolution and to monitor dynamic events noninvasively. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2016 journal article

Synthesis in living cells with the assistance of supramolecular nanocarriers

RSC Adv., 6(39), 32441–32445.

TL;DR: The results demonstrate that supramolecular delivery can be exploited to perform chemical reactions inside target cells and can lead to valuable strategies for the intracellular synthesis of drugs. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2015 journal article

A fluorescent and halochromic indolizine switch

J. Mater. Chem. C, 4(14), 2744–2747.

Source: ORCID
Added: March 13, 2023

2015 journal article

Energy-Transfer Schemes To Probe Fluorescent Nanocarriers and Their Emissive Cargo

Langmuir, 31(35), 9557–9565.

MeSH headings : Drug Carriers / chemistry; Energy Transfer; Fluorescence; HeLa Cells; Humans; Molecular Structure; Nanoparticles / chemistry
TL;DR: Operating principles and choice of supramolecular synthons are particularly valuable to monitor self-assembling nanocarriers and their cargo inside living cells and can facilitate the elucidation of the behavior of these promising delivery vehicles in a diversity of biological specimens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: March 13, 2023

2015 journal article

Optical writing and reading with a photoactivatable carbazole

Phys. Chem. Chem. Phys., 17(17), 11140–11143.

By: J. Garcia-Amorós*, S. Swaminathan*, Y. Zhang*, S. Nonell* & F. Raymo*

TL;DR: The plasmonic effects responsible for such enhancements, together with the photochemical and photophysical properties engineered into this particular photoactivatable fluorophore, permit the optical writing and reading of microscaled patterns at low illumination intensities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: ORCID
Added: March 13, 2023

2015 journal article

Photoactivatable BODIPYs Designed To Monitor the Dynamics of Supramolecular Nanocarriers

J. Am. Chem. Soc., 137(14), 4709–4719.

By: Y. Zhang*, S. Swaminathan*, S. Tang*, J. Garcia-Amorós, M. Boulina*, B. Captain*, J. Baker*, F. Raymo*

MeSH headings : Animals; Boron Compounds / chemistry; Drosophila melanogaster / embryology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Design; Fluorescent Dyes / chemistry; Indoles / chemistry; Nanoparticles / chemistry; Optical Imaging; Oxazines / chemistry; Photochemical Processes
TL;DR: This work designed molecular guests with photoactivatable fluorescence for supramolecular hosts and demonstrated that the activation of the fluorescent cargo, under optical control, permits the tracking of the nanocarrier translocation across hydrogel matrices with the sequential acquisition of fluorescence images. (via Semantic Scholar)
Source: ORCID
Added: March 13, 2023

2015 article

Self-Assembling Nanoparticles of Amphiphilic Polymers for In Vitro and In Vivo FRET Imaging

Light-Responsive Nanostructured Systems for Applications in Nanomedicine, pp. 29–59.

By: J. Garcia-Amorós, S. Tang*, Y. Zhang*, E. Thapaliya* & F. Raymo*

MeSH headings : Fluorescence Resonance Energy Transfer; Humans; In Vitro Techniques; Nanoparticles / chemistry; Polymers / chemistry
TL;DR: Self-assembling nanoparticles of amphiphilic polymers are viable delivery vehicles for transporting hydrophobic molecules across hydrophilic media and energy-transfer schemes are becoming invaluable protocols to elucidate the transport properties of these fascinating supramolecular constructs in a diversity of biological preparations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: March 13, 2023

2013 journal article

Two-Photon Absorption Properties of <i>s</i>-Triazine Derivatives With Near Octupolar Symmetry

AMR, 652-654, 542–545.

By: Y. Cui*, Y. Zhang*, L. Zhou* & F. Yu*

Source: ORCID
Added: March 13, 2023

2011 journal article

Optical Properties of Chromophores with Different Six-Membered N-Heterocyclic Aromatic Ring

AMR, 236-238, 1598–1602.

By: H. Peng*, Y. Cui*, T. Zhang*, Y. Zhang* & H. Guan*

Source: ORCID
Added: March 13, 2023

Employment

Updated: March 13th, 2023 20:44

2022 - present

North Carolina State University Raleigh, North Carolina, US
Assistant Professor Textile Engineering, Chemistry

2019 - 2022

Northwestern University Evanston, IL, US
Research Assistant Professor Biomedical Engineering

2017 - 2019

Northwestern University Evanston, IL, US
Postdoc Biomedical Engineering

2012 - 2017

University of Miami Coral Gables, FL, US
Graduate assistant Department of Chemistry

Education

Updated: May 16th, 2020 21:16

2017 - 2019

Northwestern University Evanston, IL, US
Postdoc Biomedical Engineering

2012 - 2017

University of Miami Coral Gables, FL, US
Doctorate Chemistry

2008 - 2012

Qilu University of Technology Jinan, Shandong, CN
Bachelor of Science Chemistry

Funding History

Funding history based on the linked ORCID record. Updated: March 13th, 2023 20:46

grant May 1, 2022 - February 28, 2026
Photoactivatable Fluorophores for High-Throughput Multiplexed Tracking of Single-Molecules in Live Cells
National Institute of General Medical Sciences
grant July 1, 2021 - June 30, 2023
Bright and switchable fluorophores for highly multiplexed super-resolution microscopy towards molecular interaction imaging
National Institute of General Medical Sciences
award May 1 - August 1, 2016
Photoresponsive Nanocarriers For Lipophilic Anticancer Drug Delivery With Orthogonal Control
University of Miami, Department of Chemistry

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