Works (43)

Updated: August 26th, 2023 05:02

2023 article

Investigating Uncertainties in Single-Molecule Localization Microscopy Using Experimentally Informed Monte Carlo Simulation

Yeo, W.-H., Zhang, Y., Neely, A. E., Bao, X., Sun, C., & Zhang, H. F. (2023, July 18). NANO LETTERS, Vol. 7.

By: W. Yeo*, Y. Zhang n, A. Neely*, X. Bao*, C. Sun* & H. Zhang*

author keywords: Single-molecule localization microscopy; Monte Carlosimulation; nuclear pore complex; image processing
Sources: Web Of Science, ORCID
Added: August 7, 2023

2023 review

Photoactivatable BODIPYs for Live-Cell PALM

[Review of ]. MOLECULES, 28(6).

author keywords: borondipyrromethenes (BODIPYs); fluorescence imaging; photoactivatable fluorophores (PAFs); photoactivated localization microscopy (PALM); single-molecule localization microscopy (SMLM)
MeSH headings : Microscopy, Fluorescence / methods; Boron Compounds / chemistry; Fluorescent Dyes / chemistry
Sources: Web Of Science, ORCID
Added: April 17, 2023

2023 article

Photoactivatable fluorophores for bioimaging applications

COLLOIDAL NANOPARTICLES FOR BIOMEDICAL APPLICATIONS XVIII, Vol. 12395.

By: Y. Zhang n, Y. Zheng*, A. Tomassini*, C. Hayter* & F. Raymo*

author keywords: BODIPYs; fluorescence imaging; PALM; photoactivatable fluorophores; photocages; SMLM; singlemolecule; tracking; super-resolution imaging
Sources: Web Of Science, ORCID
Added: August 21, 2023

2023 article

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

Chen, J., Tang, X., Wang, Z., Perez, A., Yao, B., Huang, K., … King, M. W. W. (2023, June 26). BIOENGINEERING & TRANSLATIONAL MEDICINE, Vol. 6.

By: J. Chen n, X. Tang n, Z. Wang n, A. Perez*, B. Yao*, K. Huang n, Y. Zhang n, M. King n

author keywords: abdominal adhesion; adhesion prevention; anti-adhesion strategy; anti-inflammatory; fibrinolytic agent; physical barrier; postsurgical adhesion
Sources: Web Of Science, ORCID
Added: July 24, 2023

2022 article

Experimental Parameters-Based Monte-Carlo Simulation of Single-Molecule Localization Microscopy of Nuclear Pore Complex to Evaluate Clustering Algorithms

Yeo, W.-H., Zhang, Y., Neely, A. E., Bao, X., Sun, C., & Zhang, H. F. (2022, September 22).

By: W. Yeo*, Y. Zhang n, A. Neely*, X. Bao*, C. Sun* & H. Zhang*

Source: ORCID
Added: March 13, 2023

2022 journal article

Minimizing Molecular Misidentification in Imaging Low-Abundance Protein Interactions Using Spectroscopic Single-Molecule Localization Microscopy

Analytical Chemistry.

By: Y. Zhang*, G. Wang*, P. Huang*, E. Sun*, J. Kweon*, Q. Li*, J. Zhe*, L. Ying*, H. Zhang*

MeSH headings : Biological Phenomena; Fluorescent Dyes / chemistry; Microscopy, Fluorescence / methods; Single Molecule Imaging / methods; Staurosporine / pharmacology
Source: ORCID
Added: March 13, 2023

2021 journal article

Investigating Single-Molecule Fluorescence Spectral Heterogeneity of Rhodamines Using High-Throughput Single-Molecule Spectroscopy

The Journal of Physical Chemistry Letters, 12(16), 3914–3921.

MeSH headings : Fluorescence; Fluorescent Dyes / chemistry; Molecular Conformation; Rhodamines / chemistry; Rotation; Single Molecule Imaging / methods
Source: ORCID
Added: March 13, 2023

2020 journal article

Accelerating multicolor spectroscopic single-molecule localization microscopy using deep learning

Biomedical Optics Express.

By: S. Gaire, Y. Zhang*, H. Li, R. Yu, H. Zhang & L. Ying

Source: ORCID
Added: March 13, 2023

2020 journal article

Compact, “Clickable” Quantum Dots Photoligated with Multifunctional Zwitterionic Polymers for Immunofluorescence and In Vivo Imaging

Bioconjugate Chemistry, 31(5), 1497–1509.

By: W. Wang*, E. Niekerk*, Y. Zhang*, L. Du*, X. Ji*, S. Wang*, J. Baker*, K. Groeniger*, F. Raymo*, H. Mattoussi*

MeSH headings : Animals; Azides / chemistry; Cell Line; Click Chemistry; Drosophila melanogaster / embryology; Fluorescent Antibody Technique; Fluorescent Dyes / chemistry; Imidazoles / chemistry; Ligands; Neurons / cytology; Optical Imaging / methods; Particle Size; Polymers / chemistry; Quantum Dots / chemistry; Signal Transduction; Sulfhydryl Compounds / chemistry
Source: ORCID
Added: March 13, 2023

2020 journal article

Live-Cell Imaging at the Nanoscale with Bioconjugatable and Photoactivatable Fluorophores

Bioconjugate Chemistry, 31(4), 1052–1062.

By: Y. Zhang* & F. Raymo*

MeSH headings : Cell Line; Cell Survival; Fluorescent Dyes / chemistry; Fluorescent Dyes / metabolism; Humans; Intracellular Space / metabolism; Light; Molecular Imaging / methods; Nanotechnology / methods
Source: ORCID
Added: March 13, 2023

2020 journal article

Photoactivatable fluorophores for single-molecule localization microscopy of live cells

Methods and Applications in Fluorescence, 8(3), 032002.

By: Y. Zhang* & F. Raymo*

MeSH headings : Humans; Microscopy, Fluorescence / methods; Single Molecule Imaging / methods
Source: ORCID
Added: March 13, 2023

2020 journal article

Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction

Langmuir, 36(9), 2291–2299.

MeSH headings : Cluster Analysis; Fluorescent Dyes / chemistry; Liposomes / chemistry; Nanoparticles / chemistry; Oxazines / chemistry; Polymers / chemistry; Single Molecule Imaging / methods; Single Molecule Imaging / statistics & numerical data
Source: ORCID
Added: March 13, 2023

2019 journal article

High-Throughput Single-Molecule Spectroscopy Resolves the Conformational Isomers of BODIPY Chromophores

The Journal of Physical Chemistry Letters, 10(21), 6807–6812.

Source: ORCID
Added: March 13, 2023

2019 journal article

Machine-learning based spectral classification for spectroscopic single-molecule localization microscopy

Optics Letters.

Source: ORCID
Added: March 13, 2023

2019 journal article

Multicolor super-resolution imaging using spectroscopic single-molecule localization microscopy with optimal spectral dispersion

Applied Optics.

By: Y. Zhang*, K. Song*, B. Dong*, J. Davis*, G. Shao*, C. Sun*, H. Zhang*

Source: ORCID
Added: March 13, 2023

2019 journal article

Three-dimensional biplane spectroscopic single-molecule localization microscopy

Optica.

Source: ORCID
Added: March 13, 2023

2019 journal article

Three-dimensional biplane spectroscopic single-molecule localization microscopy: erratum

Optica.

By: K. Song, Y. Zhang*, G. Wang*, C. Sun & H. Zhang

Source: ORCID
Added: March 13, 2023

2018 journal article

A Photoactivatable Far-Red/Near-Infrared BODIPY To Monitor Cellular Dynamics in Vivo

ACS Sensors, 3(7), 1347–1353.

MeSH headings : Animals; Boron Compounds / chemistry; Drosophila melanogaster / embryology; Fluorescent Dyes / chemistry; Infrared Rays; Models, Molecular; Optical Imaging / methods; Oxazines / chemistry; Photolysis; Pyrroles / chemistry
Source: ORCID
Added: March 13, 2023

2018 journal article

Far-Red Photoactivatable BODIPYs for the Super-Resolution Imaging of Live Cells

Journal of the American Chemical Society, 140(40), 12741–12745.

By: Y. Zhang*, K. Song*, S. Tang*, L. Ravelo*, J. Cusido*, C. Sun*, H. Zhang*, F. Raymo*

MeSH headings : Animals; Boron Compounds / analysis; COS Cells; Chlorocebus aethiops; Fluorescence; Fluorescent Dyes / analysis; Lysosomes / chemistry; Lysosomes / ultrastructure; Microscopy, Fluorescence / methods; Optical Imaging / methods; Photochemical Processes; Single Molecule Imaging / methods
Source: ORCID
Added: March 13, 2023

2018 journal article

Fluorescence activation with switchable oxazines

Chemical Communications.

Source: ORCID
Added: March 13, 2023

2018 journal article

Photochemical Barcodes

Journal of the American Chemical Society, 140(13), 4485–4488.

By: S. Tang*, Y. Zhang*, P. Dhakal*, L. Ravelo*, C. Anderson*, K. Collins*, F. Raymo*

MeSH headings : Boron Compounds / chemistry; DNA Barcoding, Taxonomic; Light; Oxyquinoline / chemistry
Source: ORCID
Added: March 13, 2023

2017 journal article

A photoactivatable light tracer

Journal of Materials Chemistry C.

By: X. Liu*, Y. Zhang*, J. Baker* & F. Raymo*

Source: ORCID
Added: March 13, 2023

2017 journal article

Bioimaging with Macromolecular Probes Incorporating Multiple BODIPY Fluorophores

Bioconjugate Chemistry, 28(5), 1519–1528.

MeSH headings : Animals; Boron Compounds / chemistry; Caenorhabditis elegans / cytology; Caenorhabditis elegans / metabolism; Diagnostic Imaging / methods; Fluorescent Dyes / chemistry; HeLa Cells; Humans; Macromolecular Substances / chemistry; Nanoparticles / chemistry; Polymers / chemistry
Source: ORCID
Added: March 13, 2023

2017 journal article

Detection of nitroaromatic explosives by a 3D hyperbranched σ–π conjugated polymer based on a POSS scaffold

J. Mater. Chem. A.

By: X. Ma*, F. Tao*, Y. Zhang*, T. Li*, F. Raymo* & Y. Cui*

Source: ORCID
Added: March 13, 2023

2017 journal article

Facile fabrication of AIE/AIEE-active fluorescent nanoparticles based on barbituric for cell imaging applications

RSC Adv., 7(48), 30229–30241.

By: K. Li*, Y. Zhang*, B. Qiao*, F. Tao*, T. Li*, Y. Ding*, F. Raymo*, Y. Cui*

Source: ORCID
Added: March 13, 2023

2017 journal article

Fluorescence patterning with mild illumination in polymer films of photocleavable oxazines

J. Mater. Chem. C, 5(5), 1179–1183.

By: E. Thapaliya*, Y. Zhang* & F. Raymo*

Source: ORCID
Added: March 13, 2023

2017 conference paper

Highlighting cancer cells with macromolecular probes

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

Ed(s): M. Osiński, W. Parak & X. Liang

Source: ORCID
Added: March 13, 2023

2017 conference paper

Probing the intracellular fate of supramolecular nanocarriers and their cargo with FRET schemes

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

By: E. Thapaliya*, C. Fowley*, B. Callan*, S. Tang*, Y. Zhang*, J. Callan*, F. Raymo*

Ed(s): M. Osiński, W. Parak & X. Liang

Source: ORCID
Added: March 13, 2023

2017 conference paper

Supramolecular delivery of photoactivatable fluorophores in developing embryos

In M. Osiński, W. J. Parak, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XII.

Ed(s): M. Osiński, W. Parak & X. Liang

Source: ORCID
Added: March 13, 2023

2016 journal article

A Photoswitchable Fluorophore for the Real-Time Monitoring of Dynamic Events in Living Organisms

Chemistry - A European Journal, 22(42), 15027–15034.

MeSH headings : Animals; Drosophila melanogaster; Fluorescent Dyes / chemistry; Photochemical Processes
Source: ORCID
Added: March 13, 2023

2016 journal article

A fluorescent and halochromic indolizine switch

J. Mater. Chem. C, 4(14), 2744–2747.

Source: ORCID
Added: March 13, 2023

2016 journal article

A pH-Gated Photocage

Advanced Optical Materials, 5.

By: Y. Zhang*, B. Captain* & F. Raymo*

Source: ORCID
Added: March 13, 2023

2016 journal article

Highlighting Cancer Cells with Halochromic Switches

ACS Sensors, 2(1), 92–101.

Source: ORCID
Added: March 13, 2023

2016 article

Self-Assembling Nanoparticles of Amphiphilic Polymers for In Vitro and In Vivo FRET Imaging

Light-Responsive Nanostructured Systems for Applications in Nanomedicine, pp. 29–59.

MeSH headings : Fluorescence Resonance Energy Transfer; Humans; In Vitro Techniques; Nanoparticles / chemistry; Polymers / chemistry
Source: ORCID
Added: March 13, 2023

2016 article

Semiconductor Quantum Dots with Photoresponsive Ligands

Sansalone, L., Tang, S., Zhang, Y., Thapaliya, E. R., Raymo, F. M., & Garcia-Amorós, J. (2016, October). Photoactive Semiconductor Nanocrystal Quantum Dots, pp. 31–60.

By: L. Sansalone, S. Tang, Y. Zhang*, E. Thapaliya, F. Raymo & J. Garcia-Amorós

Source: ORCID
Added: March 13, 2023

2016 journal article

Supramolecular delivery of fluorescent probes in developing embryos

RSC Adv., 6(76), 72756–72760.

Source: ORCID
Added: March 13, 2023

2016 conference paper

Supramolecular nanocarriers with photoresponsive cargo

In W. J. Parak, M. Osinski, & X.-J. Liang (Eds.), Colloidal Nanoparticles for Biomedical Applications XI.

Ed(s): W. Parak, M. Osinski & X. Liang

Source: ORCID
Added: March 13, 2023

2016 journal article

Synthesis in living cells with the assistance of supramolecular nanocarriers

RSC Adv., 6(39), 32441–32445.

Source: ORCID
Added: March 13, 2023

2015 journal article

Energy-Transfer Schemes To Probe Fluorescent Nanocarriers and Their Emissive Cargo

Langmuir, 31(35), 9557–9565.

By: E. Thapaliya*, C. Fowley*, B. Callan*, S. Tang*, Y. Zhang*, J. Callan*, F. Raymo*

MeSH headings : Drug Carriers / chemistry; Energy Transfer; Fluorescence; HeLa Cells; Humans; Molecular Structure; Nanoparticles / chemistry
Source: ORCID
Added: March 13, 2023

2015 journal article

Optical writing and reading with a photoactivatable carbazole

Phys. Chem. Chem. Phys., 17(17), 11140–11143.

By: J. Garcia-Amorós*, S. Swaminathan*, Y. Zhang*, S. Nonell* & F. Raymo*

Source: ORCID
Added: March 13, 2023

2015 journal article

Photoactivatable BODIPYs Designed To Monitor the Dynamics of Supramolecular Nanocarriers

J. Am. Chem. Soc., 137(14), 4709–4719.

By: Y. Zhang*, S. Swaminathan, S. Tang, J. Garcia-Amorós, M. Boulina*, B. Captain, J. Baker, F. Raymo

MeSH headings : Animals; Boron Compounds / chemistry; Drosophila melanogaster / embryology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Design; Fluorescent Dyes / chemistry; Indoles / chemistry; Nanoparticles / chemistry; Optical Imaging; Oxazines / chemistry; Photochemical Processes
Source: ORCID
Added: March 13, 2023

2013 journal article

Two-Photon Absorption Properties of s-Triazine Derivatives With Near Octupolar Symmetry

AMR, 652-654, 542–545.

By: Y. Cui*, Y. Zhang*, L. Zhou* & F. Yu*

Source: ORCID
Added: March 13, 2023

2011 journal article

Optical Properties of Chromophores with Different Six-Membered N-Heterocyclic Aromatic Ring

AMR, 236-238, 1598–1602.

By: H. Peng*, Y. Cui*, T. Zhang*, Y. Zhang* & H. Guan*

Source: ORCID
Added: March 13, 2023

Employment

Updated: March 13th, 2023 20:44

2022 - present

North Carolina State University Raleigh, North Carolina, US
Assistant Professor Textile Engineering, Chemistry

2019 - 2022

Northwestern University Evanston, IL, US
Research Assistant Professor Biomedical Engineering

2017 - 2019

Northwestern University Evanston, IL, US
Postdoc Biomedical Engineering

2012 - 2017

University of Miami Coral Gables, FL, US
Graduate assistant Department of Chemistry

Education

Updated: May 16th, 2020 21:16

2017 - 2019

Northwestern University Evanston, IL, US
Postdoc Biomedical Engineering

2012 - 2017

University of Miami Coral Gables, FL, US
Doctorate Chemistry

2008 - 2012

Qilu University of Technology Jinan, Shandong, CN
Bachelor of Science Chemistry

Funding History

Funding history based on the linked ORCID record. Updated: March 13th, 2023 20:46

grant May 1, 2022 - February 28, 2026
Photoactivatable Fluorophores for High-Throughput Multiplexed Tracking of Single-Molecules in Live Cells
National Institute of General Medical Sciences
grant July 1, 2021 - June 30, 2023
Bright and switchable fluorophores for highly multiplexed super-resolution microscopy towards molecular interaction imaging
National Institute of General Medical Sciences
award May 1 - August 1, 2016
Photoresponsive Nanocarriers For Lipophilic Anticancer Drug Delivery With Orthogonal Control
University of Miami, Department of Chemistry