Yanxia Zhang

Works (5)

Updated: July 5th, 2023 15:44

2015 journal article

Dynamics of Cyclodimerization and Viscoelasticity of Photo-Crosslinkable PVA

JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 53(5), 345–355.

By: H. Bai *, J. Xu *, Y. Zhang n, X. Liu * & O. Rojas n

author keywords: films; photo-crosslinking reaction; PVA-SbQ; QCM-D; viscoelastic properties; protein release
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Source: Web Of Science
Added: August 6, 2018

2015 journal article

Single-Molecule Resolution of Protein Dynamics on Polymeric Membrane Surfaces: The Roles of Spatial and Population Heterogeneity

ACS APPLIED MATERIALS & INTERFACES, 7(6), 3607–3617.

By: B. Langdon *, R. Mirhossaini *, J. Mabry *, I. Sriram*, A. Lajmi*, Y. Zhang n, O. Rojas n, D. Schwartz *

author keywords: protein adsorption; ultrafiltration; membrane fouling; single-molecule; total internal reflection fluorescence microscopy (TIRFM)
MeSH headings : Adsorption; Animals; Cattle; Humans; Immunoglobulin G / chemistry; Membranes, Artificial; Polymers / chemical synthesis; Polymers / chemistry; Serum Albumin, Bovine / chemistry; Surface Properties
TL;DR: It is proposed that strong surface sites may nucleate protein aggregation, initiated preferentially by protein oligomers, and accelerate ultrafiltration membrane fouling, and demonstrates that strong binding sites can be modified by changing solution conditions. (via Semantic Scholar)
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Added: August 6, 2018

2013 journal article

Bioactive Cellulose Nanofibrils for Specific Human IgG Binding

BIOMACROMOLECULES, 14(12), 4161–4168.

By: Y. Zhang n, R. Carbonell* & O. Rojas*

MeSH headings : Adsorption; Biosensing Techniques; Cellulose / chemistry; Cellulose / ultrastructure; Chromatography, Affinity; Humans; Immobilized Proteins; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Kinetics; Microscopy, Atomic Force; Nanofibers / chemistry; Nanofibers / ultrastructure; Peptide Fragments / chemistry; Polymerization; Polymethacrylic Acids / chemistry; Protein Binding; Quartz Crystal Microbalance Techniques; Signal-To-Noise Ratio; Surface Properties
TL;DR: The effects of initiator concentration and thickness of poly(AMA-co-HEMA) layer on hIgG adsorption were investigated in the developed systems, which exhibited high signal-to-noise response. (via Semantic Scholar)
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2013 journal article

Specific Binding of Immunoglobulin G with Bioactive Short Peptides Supported on Antifouling Copolymer Layers for Detection in Quartz Crystal Microgravimetry and Surface Plasmon Resonance

ANALYTICAL CHEMISTRY, 85(2), 1106–1113.

By: Y. Zhang n, N. Islam n, R. Carbonell n & O. Rojas n

MeSH headings : Binding Sites; Biofouling / prevention & control; Humans; Immunoglobulin G / chemistry; Particle Size; Peptides / chemical synthesis; Peptides / chemistry; Polymers / chemistry; Quartz Crystal Microbalance Techniques; Surface Plasmon Resonance; Surface Properties
TL;DR: The effect of copolymer molecular composition and analyte concentration was elucidated in order to design systems based on immobilized peptides for high signal-to-noise response and detection limits that meet the requirements for IgG biosensing in fluid matrixes. (via Semantic Scholar)
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2013 journal article

Specificity and Regenerability of Short Peptide Ligands Supported on Polymer Layers for Immunoglobulin G Binding and Detection

ACS APPLIED MATERIALS & INTERFACES, 5(16), 8030–8037.

By: Y. Zhang n, N. Islam n, R. Carbonell n & O. Rojas n

author keywords: short peptide ligands; immunoglobulin G detection; surface plasmon resonance; quartz crystal microgravimetry; regenerability; storage stability
MeSH headings : Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Ligands; Methacrylates / chemistry; Peptides / chemistry; Polyhydroxyethyl Methacrylate / chemistry; Polymers / chemistry; Protein Binding; Surface Plasmon Resonance
TL;DR: Results from sodium dodecyl sulfate polyacrylamide gel electrophoresis and fluorescence microscopy indicate that the bioactive system is highly specific to IgG and resistant to nonspecific interactions when tested in mixed protein solutions. (via Semantic Scholar)
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Added: August 6, 2018

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