Works (27)

2020 article

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

NATURE BIOMEDICAL ENGINEERING.

By: J. Yu, J. Wang, Y. Zhang, G. Chen, W. Mao, Y. Ye, A. Kahkoska, J. Buse, R. Langer, Z. Gu

Source: Web Of Science
Added: February 17, 2020

2020 journal article

Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis

ACS NANO, 14(6), 6878–6886.

By: L. Richter, Q. Wan, D. Wen, Y. Zhang, J. Yu, J. Kang, C. Zhu, E. McKinnon ...

Source: Web Of Science
Added: July 20, 2020

2019 journal article

A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

ACS NANO, 13(4), 4354–4360.

By: G. Yang, Q. Chen, D. Wen, Z. Chen, J. Wang, G. Chen, Z. Wang, X. Zhang ...

Source: Web Of Science
Added: June 4, 2019

2019 journal article

A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery

BIOMATERIALS SCIENCE, 7(11), 4508–4513.

By: J. Wang, Z. Wang, J. Yu, Y. Zhang, Y. Zeng & Z. Gu

Source: Web Of Science
Added: December 16, 2019

2019 journal article

Adipocytes as Anticancer Drug Delivery Depot

MATTER, 1(5), 1203–1214.

By: D. Wen, J. Wang, G. Van Den Driessche, Q. Chen, Y. Zhang, G. Chen, H. Li, J. Soto ...

Source: Web Of Science
Added: April 6, 2020

2019 review

Advances in transdermal insulin delivery

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70.

By: Y. Zhang, J. Yu, A. Kahkoska, J. Wang, J. Buse & Z. Gu

Source: Web Of Science
Added: September 9, 2019

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang, J. Yu, Y. Zhang, X. Zhang, A. Kahkoska, G. Chen, Z. Wang, W. Sun ...

Source: Web Of Science
Added: August 19, 2019

2019 journal article

Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748.

By: J. Wang, J. Yu, Y. Zhang, A. Kahkoska, Z. Wang, J. Fang, J. Whitelegge, S. Li, J. Buse, Z. Gu

Source: Web Of Science
Added: June 17, 2019

2019 journal article

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

NATURE NANOTECHNOLOGY, 14(1), 89-.

By: Q. Chen, C. Wang, X. Zhang, G. Chen, Q. Hu, H. Li, J. Wang, D. Wen ...

Source: NC State University Libraries
Added: January 21, 2019

2019 journal article

Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy

NANO RESEARCH, 12(6), 1313–1320.

By: J. Yan, X. Zhang, Y. Liu, Y. Ye, J. Yu, Q. Chen, J. Wang, Y. Zhang ...

Source: Web Of Science
Added: June 17, 2019

2018 journal article

Advances in bioresponsive closed-loop drug delivery systems

International Journal of Pharmaceutics, 544(2), 350–357.

By: J. Yu, Y. Zhang, J. Yan, A. Kahkoska & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Bioresponsive microneedles with a sheath structure for H2O2 and pH cascade-triggered insulin delivery

Small (Weinheim An Der Bergstrasse, Germany), 14(14).

By: Y. Zhang, J. Wang, J. Yu, D. Wen, A. Kahkoska, Y. Lu, X. Zhang, J. Buse, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

The potential of a microneedle patch for reducing obesity

Expert Opinion on Drug Delivery, 15(5), 431–433.

By: Y. Zhang, J. Yu, D. Wen, G. Chen & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

A melanin-mediated cancer immunotherapy patch

Science Immunology, 2(17).

By: Y. Ye, C. Wang, X. Zhang, Q. Hu, Y. Zhang, Q. Liu, D. Wen, J. Milligan ...

Source: NC State University Libraries
Added: August 6, 2018

2017 review

Bioresponsive transcutaneous patches

[Review of ]. Current Opinion in Biotechnology, 48, 28–32.

By: J. Yu, Y. Zhang, A. Kahkoska & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Hypoxia and H2O2 dual-sensitive vesicles for enhanced glucose-responsive insulin delivery

Nano Letters, 17(2), 733–739.

By: J. Yu, C. Qian, Y. Zhang, Z. Cui, Y. Zhu, Q. Shen, F. Ligler, J. Buse, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Insulin-responsive glucagon delivery for prevention of hypoglycemia

Small (Weinheim An Der Bergstrasse, Germany), 13(19).

By: J. Yu, Y. Zhang, W. Sun, A. Kahkoska, J. Wang, J. Buse, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Locally induced adipose tissue browning by microneedle patch for obesity treatment

ACS Nano, 11(9), 9223–9230.

By: Y. Zhang, Q. Liu, J. Yu, S. Yu, J. Wang, L. Qiang, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 review

Photoacoustic drug delivery

[Review of ]. Sensors (Basel, Switzerland), 17(6).

By: Y. Zhang, J. Yu, A. Kahkoska & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Smart materials and systems as artificial pancreas for diabetes treatment

Smart Materials for Tissue Engineering: Applications, 25, 358–381.

By: Y. Zhang, M. Wang, J. Yu & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation

Advanced Materials, 29(4).

By: Y. Zhang, J. Yu, J. Wang, N. Hanne, Z. Cui, C. Qian, C. Wang, H. Xin ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Elastic drug delivery: could treatments be triggered by patient movement?

Nanomedicine, 11(4), 323–325.

By: Y. Zhang, J. Yu, Y. Zhu & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Hypoxia-sensitive materials for biomedical applications

Annals of Biomedical Engineering, 44(6), 1931–1945.

By: J. Yu, Y. Zhang, X. Hu, G. Wright & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Internalized compartments encapsulated nanogels for targeted drug delivery

Nanoscale, 8(17), 9178–9184.

By: J. Yu, Y. Zhang, W. Sun, C. Wang, D. Ranson, Y. Ye, Y. Weng, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2016 review

Mechanical force-triggered drug delivery

[Review of ]. Chemical Reviews, 116(19), 12536–12563.

By: Y. Zhang, J. Yu, H. Bomba, Y. Zhu & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2015 review

Glucose-responsive synthetic closed-loop insulin delivery systems

[Review of ]. Progress in Chemistry, 27(1), 11–26.

By: Y. Zhang, J. Yu, Q. Shen & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8260–8265.

By: J. Yu, Y. Zhang, Y. Ye, R. DiSanto, W. Sun, D. Ranson, F. Ligler, J. Buse, Z. Gu

Source: NC State University Libraries
Added: August 6, 2018