Works (27)

2020 journal article

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.

Source: Web Of Science
Added: February 17, 2020

2020 journal article

Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis

ACS NANO, 14(6), 6878–6886.

By: L. Richter, Q. Wan, D. Wen, Y. Zhang, J. Yu, J. Kang, C. Zhu*, E. McKinnon* ...

author keywords: drug delivery; nanomedicine; Notch inhibitor; nonalcoholic steatohepatitis; obesity; liver fibrosis
Source: Web Of Science
Added: July 20, 2020

2019 journal article

A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

ACS NANO, 13(4), 4354–4360.

By: G. Yang*, Q. Chen, D. Wen, Z. Chen, J. Wang, G. Chen, Z. Wang*, X. Zhang ...

author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
Source: Web Of Science
Added: June 4, 2019

2019 journal article

A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery

BIOMATERIALS SCIENCE, 7(11), 4508–4513.

Source: Web Of Science
Added: December 16, 2019

2019 journal article

Adipocytes as Anticancer Drug Delivery Depot

MATTER, 1(5), 1203–1214.

By: D. Wen, J. Wang, G. Van Den Driessche, Q. Chen*, Y. Zhang, G. Chen, H. Li*, J. Soto* ...

Source: Web Of Science
Added: April 6, 2020

2019 review

Advances in transdermal insulin delivery

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70.

author keywords: Drug delivery; Transdermal delivery; Insulin; Diabetes; Iontophoresis; Electroporation; Ultrasound; Jet injection; Microneedle
Source: Web Of Science
Added: September 9, 2019

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang, J. Yu, Y. Zhang, X. Zhang, A. Kahkoska*, G. Chen, Z. Wang*, W. Sun ...

Source: Web Of Science
Added: August 19, 2019

2019 journal article

Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748.

author keywords: drug delivery; diabetes; glucose-responsive; insulin; insulin analog
Source: Web Of Science
Added: June 17, 2019

2019 journal article

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

NATURE NANOTECHNOLOGY, 14(1), 89-+.

By: Q. Chen, C. Wang n, X. Zhang, G. Chen, Q. Hu, H. Li*, J. Wang, D. Wen ...

Source: Web Of Science
Added: January 21, 2019

2019 journal article

Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy

NANO RESEARCH, 12(6), 1313–1320.

By: J. Yan n, X. Zhang, Y. Liu, Y. Ye, J. Yu, Q. Chen, J. Wang, Y. Zhang ...

author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019

2018 journal article

Advances in bioresponsive closed-loop drug delivery systems

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 544(2), 350–357.

By: J. Yu*, Y. Zhang, J. Yan*, A. Kahkoska* & Z. Gu

author keywords: Closed-loop; Drug delivery; Bioresponsive; Glucose-responsive; Enzyme-responsive
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery

SMALL, 14(14).

author keywords: diabetes; drug delivery; insulin; microneedles; stimuli-responsive
Source: Web Of Science
Added: August 6, 2018

2018 article

The potential of a microneedle patch for reducing obesity

EXPERT OPINION ON DRUG DELIVERY, Vol. 15, pp. 431–433.

By: Y. Zhang, J. Yu, D. Wen, G. Chen & Z. Gu

author keywords: Obesity; browning; microneedle; intradermal delivery
Source: Web Of Science
Added: August 6, 2018

2017 journal article

A melanin-mediated cancer immunotherapy patch

SCIENCE IMMUNOLOGY, 2(17).

By: Y. Ye n, C. Wang n, X. Zhang, Q. Hu, Y. Zhang, Q. Liu n, D. Wen, J. Milligan n ...

Source: Web Of Science
Added: August 6, 2018

2017 review

Bioresponsive transcutaneous patches

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 48, 28–32.

By: J. Yu, Y. Zhang, A. Kahkoska* & Z. Gu

Source: Web Of Science
Added: August 6, 2018

2017 journal article

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

NANO LETTERS, 17(2), 733–739.

By: J. Yu, C. Qian, Y. Zhang, Z. Cui, Y. Zhu, Q. Shen, F. Ligler, J. Buse*, Z. Gu

author keywords: Drug delivery; diabetes; insulin; glucose-responsive; hypoxia-sensitive; H2O2-sensitive
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Insulin-responsive glucagon delivery for prevention of hypoglycemia

Small (Weinheim An Der Bergstrasse, Germany), 13(19).

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment

ACS NANO, 11(9), 9223–9230.

By: Y. Zhang, Q. Liu*, J. Yu, S. Yu n, J. Wang, L. Qiang*, Z. Gu

author keywords: drug delivery; microneedle patch; obesity; browning agent; adipose tissue
Source: Web Of Science
Added: August 6, 2018

2017 review

Photoacoustic Drug Delivery

[Review of ]. SENSORS, 17(6).

By: Y. Zhang, J. Yu, A. Kahkoska* & Z. Gu

author keywords: photoacoustic imaging; drug delivery; chemotherapy; photothermal therapy
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Smart materials and systems as artificial pancreas for diabetes treatment

Smart Materials for Tissue Engineering: Applications, 25, 358–381.

By: Y. Zhang, M. Wang, J. Yu & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation

Advanced Materials, 29(4).

By: Y. Zhang, J. Yu, J. Wang*, N. Hanne n, Z. Cui, C. Qian n, C. Wang, H. Xin ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 article

Elastic drug delivery: could treatments be triggered by patient movement?

NANOMEDICINE, Vol. 11, pp. 323–325.

By: Y. Zhang, J. Yu, Y. Zhu & Z. Gu

author keywords: drug delivery; mechanical-responsive; nanoparticle; wearable devices
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Hypoxia-Sensitive Materials for Biomedical Applications

ANNALS OF BIOMEDICAL ENGINEERING, 44(6), 1931–1945.

By: J. Yu, Y. Zhang, X. Hu*, G. Wright* & Z. Gu

author keywords: Hypoxia-responsive; Drug delivery; Bioimaging; Hypoxia inducible factor-1; Bioreductive molecule
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Internalized compartments encapsulated nanogels for targeted drug delivery

NANOSCALE, 8(17), 9178–9184.

Source: Web Of Science
Added: August 6, 2018

2016 review

Mechanical Force-Triggered Drug Delivery

[Review of ]. CHEMICAL REVIEWS, 116(19), 12536–12563.

By: Y. Zhang, J. Yu, H. Bomba, Y. Zhu & Z. Gu

Source: Web Of Science
Added: August 6, 2018

2015 review

Glucose-responsive synthetic closed-loop insulin delivery systems

[Review of ]. Progress in Chemistry, 27(1), 11–26.

By: Y. Zhang, J. Yu, Q. Shen & Z. Gu

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.

author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
Source: Web Of Science
Added: August 6, 2018