Yuqi Zhang
Works (27)
Updated: August 7th, 2023 06:30
2020 journal article
Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs
NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.
MeSH headings : Animals; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Disease Models, Animal; Drug Delivery Systems; Humans; Insulin / pharmacology; Insulin Secretion / drug effects; Male; Mice, Inbred C57BL; Needles; Swine; Swine, Miniature; Transdermal Patch
Source: Web Of Science
Added: February 17, 2020
2020 journal article
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis
ACS NANO, 14(6), 6878–6886.
author keywords: drug delivery; nanomedicine; Notch inhibitor; nonalcoholic steatohepatitis; obesity; liver fibrosis
MeSH headings : Animals; Diabetes Mellitus, Type 2 / pathology; Disease Models, Animal; Glucose Intolerance / drug therapy; Glucose Intolerance / pathology; Liver / pathology; Liver Cirrhosis / drug therapy; Liver Cirrhosis / pathology; Mice; Obesity / drug therapy
Source: Web Of Science
Added: July 20, 2020
2019 journal article
A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
ACS NANO, 13(4), 4354–4360.
author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
MeSH headings : Animals; Cell Line; Delayed-Action Preparations / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Hair / chemistry; Hair / drug effects; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / growth & development; Humans; Injections, Subcutaneous; Keratins / chemistry; Mice, Inbred C57BL; Transdermal Patch
Source: Web Of Science
Added: June 4, 2019
2019 journal article
A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery
BIOMATERIALS SCIENCE, 7(11), 4508–4513.
MeSH headings : Animals; Colforsin / administration & dosage; Colforsin / pharmacology; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Delivery Systems; Glucose / metabolism; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative / antagonists & inhibitors; Glucose Transport Proteins, Facilitative / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / pharmacology; Injections, Subcutaneous; Insulin / administration & dosage; Insulin / metabolism; Insulin / pharmacology; Mice
Source: Web Of Science
Added: December 16, 2019
2019 journal article
Adipocytes as Anticancer Drug Delivery Depot
MATTER, 1(5), 1203–1214.
www.cell.com (publisher PDF)
Source: Web Of Science
Added: April 6, 2020
2019 review
Advances in transdermal insulin delivery
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70.
author keywords: Drug delivery; Transdermal delivery; Insulin; Diabetes; Iontophoresis; Electroporation; Ultrasound; Jet injection; Microneedle
MeSH headings : Administration, Cutaneous; Animals; Electroporation; Humans; Hypoglycemic Agents / administration & dosage; Insulin / administration & dosage; Iontophoresis; Microinjections; Needles; Ultrasonic Waves
Source: Web Of Science
Added: September 9, 2019
2019 journal article
Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs
SCIENCE ADVANCES, 5(7).
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
Source: Web Of Science
Added: August 19, 2019
2019 journal article
Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748.
author keywords: drug delivery; diabetes; glucose-responsive; insulin; insulin analog
MeSH headings : Animals; Blood Glucose / analysis; Blood Glucose / drug effects; Diabetes Mellitus, Experimental; Drug Delivery Systems / methods; Glucose Transport Proteins, Facilitative / antagonists & inhibitors; Hyperglycemia / drug therapy; Hypoglycemia / prevention & control; Hypoglycemic Agents / chemistry; Hypoglycemic Agents / pharmacology; Insulin / analogs & derivatives; Insulin / chemistry; Insulin / pharmacology; Mice
Source: Web Of Science
Added: June 17, 2019
2019 journal article
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
NATURE NANOTECHNOLOGY, 14(1), 89-+.
MeSH headings : Animals; Biocompatible Materials / chemistry; Calcium Carbonate / chemistry; Female; Fibrin / chemistry; Gels / chemistry; Humans; Immunity; Immunotherapy / methods; Luminescent Measurements; Melanoma, Experimental / pathology; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Phagocytosis
Source: Web Of Science
Added: January 21, 2019
2019 journal article
Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy
NANO RESEARCH, 12(6), 1313–1320.
author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019
2018 journal article
Advances in bioresponsive closed-loop drug delivery systems
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 544(2), 350–357.
author keywords: Closed-loop; Drug delivery; Bioresponsive; Glucose-responsive; Enzyme-responsive
MeSH headings : Anticoagulants / administration & dosage; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / methods; Feedback, Physiological / drug effects; Homeostasis / drug effects; Humans; Hypoglycemic Agents / administration & dosage; Thrombosis / blood; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery
SMALL, 14(14).
author keywords: diabetes; drug delivery; insulin; microneedles; stimuli-responsive
MeSH headings : Animals; Drug Delivery Systems / methods; Humans; Hydrogen Peroxide / chemistry; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Mice; Oxidation-Reduction
Source: Web Of Science
Added: August 6, 2018
2018 article
The potential of a microneedle patch for reducing obesity
EXPERT OPINION ON DRUG DELIVERY, Vol. 15, pp. 431–433.
author keywords: Obesity; browning; microneedle; intradermal delivery
Source: Web Of Science
Added: August 6, 2018
2017 journal article
A melanin-mediated cancer immunotherapy patch
SCIENCE IMMUNOLOGY, 2(17).
MeSH headings : Animals; Cancer Vaccines / immunology; Cancer Vaccines / metabolism; Cell Line, Tumor; Dendritic Cells / immunology; Dendritic Cells / metabolism; Female; Immunotherapy / instrumentation; Immunotherapy / methods; Infrared Rays; Kaplan-Meier Estimate; Melanins / immunology; Melanins / metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Needles; Neoplasms, Experimental / immunology; Neoplasms, Experimental / pathology; Neoplasms, Experimental / therapy; Transdermal Patch; Tumor Burden / immunology
Source: Web Of Science
Added: August 6, 2018
2017 review
Bioresponsive transcutaneous patches
[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 48, 28–32.
MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / methods; Drug Monitoring / methods; Humans; Needles; Skin; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery
NANO LETTERS, 17(2), 733–739.
author keywords: Drug delivery; diabetes; insulin; glucose-responsive; hypoxia-sensitive; H2O2-sensitive
MeSH headings : Animals; Blood Glucose / metabolism; Cell Hypoxia; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Carriers / chemistry; Drug Liberation; Glucose / metabolism; Glucose Oxidase / metabolism; HeLa Cells; Humans; Hydrogen Peroxide / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Insulin / administration & dosage; Insulin / chemistry; Male; Mice, Inbred C57BL; Nitroimidazoles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Insulin-responsive glucagon delivery for prevention of hypoglycemia
Small (Weinheim An Der Bergstrasse, Germany), 13(19).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment
ACS NANO, 11(9), 9223–9230.
author keywords: drug delivery; microneedle patch; obesity; browning agent; adipose tissue
MeSH headings : Adipocytes, White / drug effects; Adipose Tissue, White / drug effects; Animals; Anti-Obesity Agents / administration & dosage; Anti-Obesity Agents / therapeutic use; Drug Delivery Systems / instrumentation; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / therapeutic use; Male; Mice, Inbred C57BL; Obesity / drug therapy; Rosiglitazone / administration & dosage; Rosiglitazone / therapeutic use; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018
2017 review
Photoacoustic Drug Delivery
[Review of ]. SENSORS, 17(6).
author keywords: photoacoustic imaging; drug delivery; chemotherapy; photothermal therapy
MeSH headings : Drug Delivery Systems; Humans; Optical Imaging; Photoacoustic Techniques; Spectrum Analysis; Theranostic Nanomedicine
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Smart materials and systems as artificial pancreas for diabetes treatment
Smart Materials for Tissue Engineering: Applications, 25, 358–381.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation
Advanced Materials, 29(4).
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2016 article
Elastic drug delivery: could treatments be triggered by patient movement?
NANOMEDICINE, Vol. 11, pp. 323–325.
author keywords: drug delivery; mechanical-responsive; nanoparticle; wearable devices
MeSH headings : Drug Delivery Systems; Elasticity; Humans; Movement; Patients
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Hypoxia-Sensitive Materials for Biomedical Applications
ANNALS OF BIOMEDICAL ENGINEERING, 44(6), 1931–1945.
author keywords: Hypoxia-responsive; Drug delivery; Bioimaging; Hypoxia inducible factor-1; Bioreductive molecule
MeSH headings : Animals; Cell Hypoxia; Humans; Hypoxia-Inducible Factor 1 / metabolism; Tissue Scaffolds / chemistry
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Internalized compartments encapsulated nanogels for targeted drug delivery
NANOSCALE, 8(17), 9178–9184.
MeSH headings : Doxorubicin / administration & dosage; Drug Delivery Systems; Ferrous Compounds; Hyaluronic Acid; Nanoparticles; Silicon Dioxide
Source: Web Of Science
Added: August 6, 2018
2016 review
Mechanical Force-Triggered Drug Delivery
[Review of ]. CHEMICAL REVIEWS, 116(19), 12536–12563.
MeSH headings : Animals; Drug Carriers / chemistry; Drug Carriers / pharmacology; Drug Delivery Systems / methods; Liposomes / chemistry; Liposomes / pharmacology; Magnetic Phenomena; Mechanical Phenomena; Microbubbles; Nanoparticles / chemistry; Ultrasonic Waves
Source: Web Of Science
Added: August 6, 2018
2015 review
Glucose-responsive synthetic closed-loop insulin delivery systems
[Review of ]. Progress in Chemistry, 27(1), 11–26.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.
author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
MeSH headings : Animals; Blood Glucose / analysis; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Hypoxia / metabolism; Insulin / administration & dosage; Insulin / chemistry; Insulin / metabolism; Male; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidation-Reduction; Reproducibility of Results
Source: Web Of Science
Added: August 6, 2018
