Amanda Yi-Hui Zhou

Characterizing PFAS hazards and risks: a human population-based in vitro cardiotoxicity assessment strategy

HUMAN GENOMICS, 18(1).

Control of false discoveries in grouped hypothesis testing for eQTL data

BMC BIOINFORMATICS, 25(1).

Control of false discoveries in grouped hypothesis testing for eQTL data

Springer Nature.

Genetic variation in severe cystic fibrosis liver disease is associated with novel mechanisms for disease pathogenesis

Stonebraker, J., Pace, R., Gallins, P., Dang, H., Aksit, M., Faino, A., … Knowles, M. (2024, March 27). HEPATOLOGY, Vol. 3.

Hazard and risk characterization of 56 structurally diverse PFAS using a targeted battery of broad coverage assays using six human cell types

TOXICOLOGY, 503.

Liver eQTL meta-analysis illuminates potential molecular mechanisms of cardiometabolic traits

AMERICAN JOURNAL OF HUMAN GENETICS, 111(9).

Predicting Microbiome Growth Dynamics under Environmental Perturbations

Applied Microbiology.

AI in healthcare: navigating opportunities and challenges in digital communication

[Review of ]. FRONTIERS IN DIGITAL HEALTH, 5.

Association of Pseudomonas aeruginosa infection stage with lung function trajectory in children with cystic fibrosis

JOURNAL OF CYSTIC FIBROSIS, 22(5), 857–863.

Genetic Modifiers of Cystic Fibrosis Lung Disease Severity

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(10), 1324–1333.

Integrative Chemical-Biological Grouping of Complex High Production Volume Substances from Lower Olefin Manufacturing Streams

TOXICS, 11(7).

Leveraging Scheme for Cross-Study Microbiome Machine Learning Prediction and Feature Evaluations

BIOENGINEERING-BASEL, 10(2).

Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage composite likelihood

Ting, B. W. W., Wright, F. A., & Zhou, Y.-H. (2023, May 22). BIOMETRICAL JOURNAL.

A Double Penalty Model for Ensemble Learning

MATHEMATICS, 10(23).

A Machine Learning Pipeline for Mortality Prediction in the ICU

International Journal of Digital Health, 2(1).

A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures

TOXICS, 10(8).

A resource for integrated genomic analysis of the human liver

SCIENTIFIC REPORTS, 12(1).

Accounting for population structure in genetic studies of cystic fibrosis

HUMAN GENETICS AND GENOMICS ADVANCES, 3(3).

C3NA: correlation and consensus-based cross-taxonomy network analysis for compositional microbial data

BMC BIOINFORMATICS, 23(1).

Fast Multivariate Probit Estimation via a Two-Stage Composite Likelihood

Ting, B., Wright, F., & Zhou, Y.-H. (2022, February 15). STATISTICS IN BIOSCIENCES, Vol. 2.

Improve the Colorectal Cancer Diagnosis Using Gut Microbiome Data

FRONTIERS IN MOLECULAR BIOSCIENCES, 9.

Leveraging TOPMed imputation server and constructing a cohort-specific imputation reference panel to enhance genotype imputation among cystic fibrosis patients

HUMAN GENETICS AND GENOMICS ADVANCES, 3(2).

MagicalRsq: Machine-learning-based genotype imputation quality calibration

AMERICAN JOURNAL OF HUMAN GENETICS, 109(11), 1986–1997.

Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis

AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1894–1908.

Comparing encounter-based and annualized chronic pseudomonas infection definitions in cystic fibrosis

JOURNAL OF CYSTIC FIBROSIS, 21(1), 40–44.

Complete CFTR gene sequencing in 5,058 individuals with cystic fibrosis informs variant-specific treatment

JOURNAL OF CYSTIC FIBROSIS, 21(1), 463–470.

Eigenvector-based sparse canonical correlation analysis: Fast computation for estimation of multiple canonical vectors

JOURNAL OF MULTIVARIATE ANALYSIS, 185.

ImputEHR: A Visualization Tool of Imputation for the Prediction of Biomedical Data

FRONTIERS IN GENETICS, 12.

Potential Human Health Hazard of Post-Hurricane Harvey Sediments in Galveston Bay and Houston Ship Channel: A Case Study of Using In Vitro Bioactivity Data to Inform Risk Management Decisions

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(24).

Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes

FOOD AND CHEMICAL TOXICOLOGY, 149.

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning

Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).

Exploring the Limits of Combined Image/'omics Analysis for Non-cancer Histological Phenotypes

FRONTIERS IN GENETICS, 11.

Systematic Comparisons for Composition Profiles, Taxonomic Levels, and Machine Learning Methods for Microbiome-Based Disease Prediction

FRONTIERS IN MOLECULAR BIOSCIENCES, 7.

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes

CLINICAL PHARMACOLOGY & THERAPEUTICS, 107(6), 1383–1393.

A Review and Tutorial of Machine Learning Methods for Microbiome Host Trait Prediction

[Review of ]. FRONTIERS IN GENETICS, 10.

A note on cyclic shift permutation testing for large eigenvalues

Stat, 8(1).

Marker-Trait Complete Analysis

Zhou, Y.-H., Gallins, P., & Wright, F. (2019, November 9). (Vol. 11). Vol. 11.

Set‐based differential covariance testing for genomics

Stat, 8(1).

A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Cell Reports, 23(2), 327–336.

A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Cell Reports, 23(2), 327–336.

A survey of high dimension low sample size asymptotics

AUSTRALIAN & NEW ZEALAND JOURNAL OF STATISTICS, 60(1), 4–19.

A zero-inflated beta-binomial model for microbiome data analysis

STAT, 7(1).

Airway mucosal host defense is key to genomic regulation of cystic fibrosis lung disease severity

American Journal of Respiratory and Critical Care Medicine, 197(1), 79–93.

Airway mucosal host defense is key to genomic regulation of cystic fibrosis lung disease severity

American Journal of Respiratory and Critical Care Medicine, 197(1), 79–93.

A Pipeline for High-Throughput Concentration Response Modeling of Gene Expression for Toxicogenomics

Frontiers in Genetics, 8, 168.

A Two-Stage Hidden Markov Model Design for Biomarker Detection, with Application to Microbiome Research

Statistics in Biosciences, 10(1), 41–58.

A procedure to detect general association based on concentration of ranks

Stat, 6(1), 88–101.

Changes in vaginal community state types reflect major shifts in the microbiome

Microbial Ecology in Health and Disease, 28(1), 1303265.

Changes in vaginal community state types reflect major shifts in the microbiome

Microbial Ecology in Health and Disease, 28(1), 1303265.

Computation of ancestry scores with mixed families and unrelated individuals

BIOMETRICS, 74(1), 155–164.

Dynamic landscape and regulation of RNA editing in mammals

Nature, 550(7675), 249–254.

Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse

TOXICOLOGICAL SCIENCES, 160(1), 95–110.

Eigenvalue Significance Testing for Genetic Association

Biometrics.

Estimation of cis-eQTL effect sizes using a log of linear model

BIOMETRICS, 74(2), 616–625.

Genetic effects on gene expression across human tissues

Nature, 550(7675), 204–213.

The impact of rare variation on gene expression across tissues

Nature, 550(7675), 239–243.

Estimation of interpretable eQTL effect sizes using a log of linear model

ArXiv Preprint ArXiv:1605.08799.

Genomic characterization of metformin hepatic response

PLoS Genetics, 12(11), e1006449.

Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium

PLoS One, 11(12).

Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium

PloS One, 11(12), e0167503.

Poster: risk-based attack surface approximation

Symposium and Bootcamp on the Science of Security, 121–123.

The projack: a resampling approach to correct for ranking bias in high-throughput studies

Biostatistics (Oxford, England), 17(1), 54–64.

Visualization of robust L1PCA

Stat, 5(1), 173–184.

Effect of predicted protein-truncating genetic variants on the human transcriptome

Science, 348(6235), 666–669.

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Human Molecular Genetics, 24(15), 4464–4479.

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

Human Molecular Genetics, 24(15), 4464–4479.

Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes

The American Journal of Human Genetics, 96(2), 318–328.

Gene expression in transformed lymphocytes reveals variation in endomembrane and HLA pathways modifying cystic fibrosis pulmonary phenotypes

The American Journal of Human Genetics, 96(2), 318–328.

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6(1).

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6.

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6, 8382.

High dimension low sample size asymptotics of robust PCA

ELECTRONIC JOURNAL OF STATISTICS, 9(1), 204–218.

High dimension low sample size asymptotics of robust PCA

Electronic Journal of Statistics, 9(1), 204–218.

Hypothesis testing at the extremes: fast and robust association for high-throughput data

BIOSTATISTICS, 16(3), 611–625.

Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

Metabolomic evaluation of neutrophilic airway inflammation in cystic fibrosis

Chest, 148(2), 507–515.

Pathway Analysis for RNA-Seq Data Using a Score-Based Approach

BIOMETRICS, 72(1), 165–174.

PathwaySeq: Pathway analysis for RNA-Seq data using a score-based approach

Dim (Data. Test), 1(1000), 448.

Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

ENVIRONMENTAL HEALTH PERSPECTIVES, 123(5), 458–466.

Population-based in vitro hazard and concentration--response assessment of chemicals: the 1000 genomes high-throughput screening study

Environmental Health Perspectives, 123(5), 458.

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

Science, 348(6235), 648–660.

The projack: a resampling approach to correct for ranking bias in high-throughput studies

Biostatistics, 17(1), 54–64.

Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs

Epigenetics, 9(2), 212–221.

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430.

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

ENVIRONMENTAL HEALTH PERSPECTIVES, 122(5), 456–463.

Physiologically based pharmacokinetic (PBPK) modeling of interstrain variability in trichloroethylene metabolism in the mouse

Environmental Health Perspectives, 122(5), 456.

RNA-Seq pathway analysis

Empirical pathway analysis, without permutation

Biostatistics, (doi:10.1093/biostatistics/kxt004), 1–13.

Metabolomic Evaluation Of Cystic Fibrosis Airways Disease

In A26. PEDIATRIC CYSTIC FIBROSIS (pp. A1165–A1165). American Thoracic Society.

Skill-assessments of statistical and Ensemble Kalman Filter data assimilative analyses using surface and deep observations in the Gulf of Mexico

Frontiers of Earth Science, 7(3), 271–281.

Space-time clustering and the permutation moments of quadratic forms

Stat, 2(1), 292–302.

Stochastic comparisons in a price-quantity setting firm with uncertain demand and emergency procurement

Journal of Systems Science and Systems Engineering, 22(4), 401–420.

Stochastic comparisons in a price-quantity setting firm with uncertain demand and emergency procurement

Journal of Systems Science and Systems Engineering, 22(4), 401–420.

Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model

Toxicological Sciences.

Simple and accurate trend tests using a permutation approximation

Single Nucleotide Polymorphism (SNP) Detection and Genotype Calling from Massively Parallel Sequencing (MPS) Data

Statistics in Biosciences, 5(1), 3–25.