Zuzana Drobna

Sen, D., Drobna, Z., & Keung, A. J. (2021). Evaluation of UBE3A antibodies in mice and human cerebral organoids. SCIENTIFIC REPORTS, 11(1). https://doi.org/10.1038/s41598-021-85923-x

Drobna, Z. (2020). Activation of Lrrk2 and alpha-Synuclein in substantia nigra, striatum, and cerebellum after chronic exposure to arsenite. TOXICOLOGY AND APPLIED PHARMACOLOGY, 408. https://doi.org/10.1016/j.taap.2020.115278

Sen, D., Voulgaropoulos, A., Drobna, Z., & Keung, A. J. (2020). Human Cerebral Organoids Reveal Early Spatiotemporal Dynamics and Pharmacological Responses of UBE3A. STEM CELL REPORTS, 15(4), 845–854. https://doi.org/10.1016/j.stemcr.2020.08.006

Drobna, Z., Talarovicova, A., Schrader, H. E., Fennell, T. R., Snyder, R. W., & Rissman, E. F. (2019). Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with Bisphenol A and S. TOXICOLOGY, 420, 66–72. https://doi.org/10.1016/j.tox.2019.03.016

Wolstenholme, J. T., Drobna, Z., Henriksen, A. D., Goldsby, J. A., Stevenson, R., Irvin, J. W., … Rissman, E. F. (2019). Transgenerational Bisphenol A Causes Deficits in Social Recognition and Alters Postsynaptic Density Genes in Mice. ENDOCRINOLOGY, 160(8), 1854–1867. https://doi.org/10.1210/en.2019-00196

Drobna, Z., Henriksen, A. D., Wolstenholme, J. T., Montiel, C., Lambeth, P. S., Shang, S., … Rissman, E. F. (2018). Transgenerational Effects of Bisphenol A on Gene Expression and DNA Methylation of Imprinted Genes in Brain. ENDOCRINOLOGY, 159(1), 132–144. https://doi.org/10.1210/en.2017-00730

Huang, M. C., Douillet, C., Su, M., Zhou, K., Wu, T., Chen, W., … Stýblo, M. (2017). Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Archives of Toxicology, 91(1), 189–202. https://doi.org/10.1007/S00204-016-1676-0

Laine, J. E., Bailey, K. A., Olshan, A. F., Smeester, L., Drobna, Z., Styblo, M., … Fry, R. C. (2017). Neonatal Metabolomic Profiles Related to Prenatal Arsenic Exposure. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 51(1), 625–633. https://doi.org/10.1021/acs.est.6b04374

Grau-Perez, M., Kuo, C.-C., Spratlen, M., Thayer, K. A., Mendez, M. A., Hamman, R. F., … Navas-Acien, A. (2017). The Association of Arsenic Exposure and Metabolism With Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study. DIABETES CARE, 40(1), 46–53. https://doi.org/10.2337/dc16-0810

Drobna, Z., Martin, E., Kim, K. S., Smeester, L., Bommarito, P., Rubio-Andrade, M., … Fry, R. C. (2016). Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis. REPRODUCTIVE TOXICOLOGY, 61, 28–38. https://doi.org/10.1016/j.reprotox.2016.02.017

Mendez, M. A., González-Horta, C., Sánchez-Ramírez, B., Ballinas-Casarrubias, L., Cerón, R. H., Morales, D. V., … Stýblo, M. (2016). Arsenic exposure and cardiometabolic risk in Chihuahua, Mexico. Toxicology Letters, 259, S32–S33. https://doi.org/10.1016/J.TOXLET.2016.07.653

Xu, X., Drobna, Z., Voruganti, V. S., Barron, K., Gonzalez-Horta, C., Sanchez-Ramirez, B., … Mendez, M. A. (2016). Association Between Variants in Arsenic (+3 Oxidation State) Methyltranserase (AS3MT) and Urinary Metabolites of Inorganic Arsenic: Role of Exposure Level. TOXICOLOGICAL SCIENCES, 153(1), 112–123. https://doi.org/10.1093/toxsci/kfw112

Currier, J. M., Douillet, C., Drobná, Z., & Stýblo, M. (2016). Oxidation state specific analysis of arsenic species in tissues of wild-type and arsenic (+ 3 oxidation state) methyltransferase-knockout mice. Journal of Environmental Sciences, 49, 104–112. https://doi.org/10.1016/J.JES.2016.06.018

Rager, J. E., Tilley, S. K., Tulenko, S. E., Smeester, L., Ray, P. D., Yosim, A., … Fry, R. C. (2015). Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer. Chemical Research in Toxicology, 28(6), 1144–1155. https://doi.org/10.1021/TX500393Y

Bailey, K. A., Wu, M. C., Ward, W. O., Smeester, L., Rager, J. E., García-Vargas, G., … Fry, R. C. (2013). Arsenic and the Epigenome: Interindividual Differences in Arsenic Metabolism Related to Distinct Patterns of DNA Methylation. Journal of Biochemical and Molecular Toxicology, 27(2), 106–115. https://doi.org/10.1002/jbt.21462

Rager, J. E., Bailey, K. A., Smeester, L., Miller, S. K., Parker, J. S., Laine, J. E., … Fry, R. C. (2013). Prenatal arsenic exposure and the epigenome: Altered microRNAs associated with innate and adaptive immune signaling in newborn cord blood. Environmental and Molecular Mutagenesis, 55(3), 196–208. https://doi.org/10.1002/EM.21842

Drobná, Z., Del Razo, L. M., García-Vargas, G. G., Sánchez-Peña, L. C., Barrera-Hernández, A., Stýblo, M., & Loomis, D. (2012). Environmental exposure to arsenic, AS3MT polymorphism and prevalence of diabetes in Mexico. Journal of Exposure Science & Environmental Epidemiology, 23(2), 151–155. https://doi.org/10.1038/jes.2012.103

Ding, L., Saunders, R. J., Drobná, Z., Walton, F. S., Xun, P., Thomas, D. J., & Stýblo, M. (2012). Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione. Toxicology and Applied Pharmacology, 264(1), 121–130. https://doi.org/10.1016/j.taap.2012.07.024

Tsang, V., Fry, R. C., Niculescu, M. D., Rager, J. E., Saunders, J., Paul, D. S., … Drobná, Z. (2012). The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic. Toxicology and Applied Pharmacology, 264(3), 439–450. https://doi.org/10.1016/j.taap.2012.08.022

Smeester, L., Rager, J. E., Bailey, K. A., Guan, X., Smith, N., García-Vargas Gonzalo, … Fry, R. C. (2011). Epigenetic Changes in Individuals with Arsenicosis. Chemical Research in Toxicology, 24(2), 165–167. https://doi.org/10.1021/tx1004419

Drobná, Z., Del Razo, L. M., Garcia-Vargas, G., Sánchez-Ramírez, B., González-Horta, C., Ballinas-Casarrubias, L., … Stýblo, M. (2011). Identification of theGST-T1andGST-M1Null Genotypes Using High Resolution Melting Analysis. Chemical Research in Toxicology, 25(1), 216–224. https://doi.org/10.1021/tx200457u

Drobná, Z., Walton, F. S., Harmon, A. W., Thomas, D. J., & Stýblo, M. (2010). Interspecies differences in metabolism of arsenic by cultured primary hepatocytes. Toxicology and Applied Pharmacology, 245(1), 47–56. https://doi.org/10.1016/j.taap.2010.01.015

Valenzuela, O. L., Drobná, Z., Hernández-Castellanos, E., Sánchez-Peña, L. C., García-Vargas, G. G., Borja-Aburto, V. H., … Del Razo, L. M. (2009). Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions. Toxicology and Applied Pharmacology, 239(2), 200–207. https://doi.org/10.1016/j.taap.2009.06.007

Drobna, Z., Naranmandura, H., Kubachka, K. M., Edwards, B. C., Herbin-Davis, K., Styblo, M., … Thomas, D. J. (2009). Disruption of the Arsenic (+3 Oxidation State) Methyltransferase Gene in the Mouse Alters the Phenotype for Methylation of Arsenic and Affects Distribution and Retention of Orally Administered Arsenate. Chemical Research in Toxicology, 22(10), 1713–1720. https://doi.org/10.1021/tx900179r

Drobná, Z., Walton, F. S., Paul, D. S., Xing, W., Thomas, D. J., & Stýblo, M. (2009). Metabolism of arsenic in human liver: the role of membrane transporters. Archives of Toxicology, 84(1), 3–16. https://doi.org/10.1007/S00204-009-0499-7

Matoušek, T., Hernández-Zavala, A., Svoboda, M., Langrová, L., Adair, B. M., Drobná, Z., … Dědina, J. (2008). Oxidation state specific generation of arsines from methylated arsenicals based on l-cysteine treatment in buffered media for speciation analysis by hydride generation-automated cryotrapping-gas chromatography-atomic absorption spectrometry with the multiatomizer. Spectrochimica Acta Part B: Atomic Spectroscopy, 63(3), 396–406. https://doi.org/10.1016/j.sab.2007.11.037

Hernández-Zavala, A., Matoušek, T., Drobná, Z., Paul, D. S., Walton, F., Adair, B. M., … Stýblo, M. (2008). Speciation analysis of arsenic in biological matrices by automated hydride generation-cryotrapping-atomic absorption spectrometry with multiple microflame quartz tube atomizer (multiatomizer). J. Anal. At. Spectrom., 23(3), 342–351. https://doi.org/10.1039/b706144g

Drobná, Z., Xing, W., Thomas, D. J., & Stýblo, M. (2006). shRNA Silencing of AS3MT Expression Minimizes Arsenic Methylation Capacity of HepG2 Cells. Chemical Research in Toxicology, 19(7), 894–898. https://doi.org/10.1021/tx060076u

Li, J., Waters, S. B., Drobna, Z., Devesa, V., Styblo, M., & Thomas, D. J. (2005). Arsenic (+3 oxidation state) methyltransferase and the inorganic arsenic methylation phenotype. Toxicology and Applied Pharmacology, 204(2), 164–169. https://doi.org/10.1016/j.taap.2004.12.002

Adair, B. M., Waters, S. B., Devesa, V., Drobna, Z., Styblo, M., & Thomas, D. J. (2005). Commonalities in Metabolism of Arsenicals. Environmental Chemistry, 2(3), 161. https://doi.org/10.1071/EN05054

Drobna, Z., Waters, S., Devesa, V., Harmon, A., Thomas, D., & Styblo, M. (2005). Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase. Toxicology and Applied Pharmacology, 207(2), 147–159. https://doi.org/10.1016/j.taap.2004.12.007

Devesa, V., Maria Del Razo, L., Adair, B., Drobná, Z., Waters, S. B., Hughes, M. F., … Thomas, D. J. (2004). Comprehensive analysis of arsenic metabolites by pH-specific hydride generation atomic absorption spectrometry. J. Anal. At. Spectrom., 19(11), 1460–1467. https://doi.org/10.1039/b407388f

Walton, F., Harmon, A. W., Paul, D. S., Drobna, Z., Patel, Y. M., & Styblo, M. (2004). Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes. Toxicology and Applied Pharmacology, 198(3), 424–433. https://doi.org/10.1016/j.taap.2003.10.026

Drobná, Z., Waters, S. B., Walton, F. S., LeCluyse, E. L., Thomas, D. J., & Stýblo, M. (2004). Interindividual variation in the metabolism of arsenic in cultured primary human hepatocytes. Toxicology and Applied Pharmacology, 201(2), 166–177. https://doi.org/10.1016/j.taap.2004.05.004

Kupsáková, I., Rybár, A., Dočolomanský, P., Drobná, Z., Stein, U., Walther, W., … Breier, A. (2004). Reversal of P-glycoprotein mediated vincristine resistance of L1210/VCR cells by analogues of pentoxifylline. European Journal of Pharmaceutical Sciences, 21(2-3), 283–293. https://doi.org/10.1016/j.ejps.2003.10.019