Zhen Gu
Works (195)
Updated: August 28th, 2023 21:15
2022 journal article
Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy
NATIONAL SCIENCE REVIEW, 9(3).
author keywords: drug delivery; CAR T therapy; microneedle patch; solid tumor treatment; cell delivery
academic.oup.com (publisher PDF)
Source: Web Of Science
Added: March 28, 2022
2021 article
Bioorthogonal catalytic patch
Chen, Z., Li, H., Bian, Y., Wang, Z., Chen, G., Zhang, X., … Gu, Z. (2021, May 10). NATURE NANOTECHNOLOGY.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacokinetics; Antineoplastic Agents / pharmacology; Catalysis; Drug Delivery Systems; Hep G2 Cells; Humans; Melanoma, Experimental; Metal Nanoparticles / chemistry; Metal Nanoparticles / therapeutic use; Mice; Palladium / chemistry; Palladium / pharmacokinetics; Palladium / pharmacology; Prodrugs / chemistry; Prodrugs / pharmacokinetics; Prodrugs / pharmacology; Titanium / chemistry; Titanium / pharmacokinetics; Titanium / pharmacology
Source: Web Of Science
Added: June 10, 2021
2021 article
Inhibition of post-surgery tumour recurrence via a hydrogel releasing CAR-T cells and anti-PDL1-conjugated platelets
Hu, Q., Li, H., Archibong, E., Chen, Q., Ruan, H., Ahn, S., … Gu, Z. (2021, April 26). NATURE BIOMEDICAL ENGINEERING.
MeSH headings : Animals; Antibodies, Monoclonal, Humanized; Blood Platelets; Cell-Derived Microparticles; Hydrogels; Immunotherapy, Adoptive; Mice; Neoplasm Recurrence, Local / prevention & control; T-Lymphocytes; Tumor Microenvironment
Source: Web Of Science
Added: June 10, 2021
2021 journal article
Integrated microneedle-smartphone nucleic acid amplification platform for in-field diagnosis of plant diseases
BIOSENSORS & BIOELECTRONICS, 187.
author keywords: Plant disease diagnostics; Nucleic acid extraction; Microneedle; Isothermal amplification; Smartphone
MeSH headings : Biosensing Techniques; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Plant Diseases; Smartphone
Sources: Web Of Science, ORCID
Added: June 14, 2021
2020 journal article
CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation
SCIENCE ADVANCES, 6(21).
MeSH headings : CRISPR-Cas Systems; Cholesterol; DNA / genetics; DNA / metabolism; Gene Editing; Polymers / metabolism; Proprotein Convertase 9 / genetics; Proprotein Convertase 9 / metabolism; RNA / genetics; Ribonucleoproteins / genetics
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Engineered PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes
ADVANCED MATERIALS, 32(26).
author keywords: drug delivery; immune tolerance; platelets; programmed death-ligand 1 (PD-L1); type 1 diabetes (T1D)
MeSH headings : Animals; B7-H1 Antigen / genetics; B7-H1 Antigen / metabolism; Blood Glucose / analysis; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Diabetes Mellitus, Type 1 / pathology; Diabetes Mellitus, Type 1 / therapy; Diabetes Mellitus, Type 1 / veterinary; Genetic Engineering; Immune Tolerance; Insulin / blood; Insulin-Secreting Cells / cytology; Insulin-Secreting Cells / immunology; Insulin-Secreting Cells / metabolism; Megakaryocyte Progenitor Cells / cytology; Megakaryocyte Progenitor Cells / metabolism; Megakaryocyte Progenitor Cells / transplantation; Mice; Mice, Inbred NOD; T-Lymphocytes, Regulatory / cytology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism
Source: Web Of Science
Added: June 8, 2020
2020 journal article
Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs
NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.
MeSH headings : Animals; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Disease Models, Animal; Drug Delivery Systems; Humans; Insulin / pharmacology; Insulin Secretion / drug effects; Male; Mice, Inbred C57BL; Needles; Swine; Swine, Miniature; Transdermal Patch
Source: Web Of Science
Added: February 17, 2020
2020 review
Non-transdermal microneedles for advanced drug delivery
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 165-166, 41–59.
author keywords: Microneedle; Implant; Drug delivery; Non-transdermal; Biocompatibility; Biodegradability
MeSH headings : Administration, Topical; Biological Transport; Drug Delivery Systems / methods; Equipment Design; Humans; Microinjections / instrumentation; Microinjections / methods; Microtechnology / methods; Polymers; Prostheses and Implants
Source: Web Of Science
Added: January 11, 2021
2020 journal article
Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis
ACS NANO, 14(6), 6878–6886.
author keywords: drug delivery; nanomedicine; Notch inhibitor; nonalcoholic steatohepatitis; obesity; liver fibrosis
MeSH headings : Animals; Diabetes Mellitus, Type 2 / pathology; Disease Models, Animal; Glucose Intolerance / drug therapy; Glucose Intolerance / pathology; Liver / pathology; Liver Cirrhosis / drug therapy; Liver Cirrhosis / pathology; Mice; Obesity / drug therapy
Source: Web Of Science
Added: July 20, 2020
2019 journal article
A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade
ADVANCED MATERIALS, 31(17).
author keywords: bioresponsive materials; drug delivery; epigenetic modulation; immune checkpoint blockade; immunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Antibodies, Monoclonal, Humanized; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Calcium Carbonate / chemistry; Cell Line, Tumor; Cytidine / analogs & derivatives; Cytidine / pharmacology; Drug Delivery Systems / methods; Drug Liberation; Drug Therapy, Combination / methods; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents / chemistry; Immunosuppressive Agents / pharmacology; Immunotherapy / methods; Melanoma / drug therapy; Nanoparticles / chemistry; Programmed Cell Death 1 Receptor / metabolism; Reactive Oxygen Species / metabolism; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: May 13, 2019
2019 journal article
A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
ACS NANO, 13(4), 4354–4360.
author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
MeSH headings : Animals; Cell Line; Delayed-Action Preparations / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Hair / chemistry; Hair / drug effects; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / growth & development; Humans; Injections, Subcutaneous; Keratins / chemistry; Mice, Inbred C57BL; Transdermal Patch
Source: Web Of Science
Added: June 4, 2019
2019 journal article
A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery
BIOMATERIALS SCIENCE, 7(11), 4508–4513.
MeSH headings : Animals; Colforsin / administration & dosage; Colforsin / pharmacology; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Delivery Systems; Glucose / metabolism; Glucose Tolerance Test; Glucose Transport Proteins, Facilitative / antagonists & inhibitors; Glucose Transport Proteins, Facilitative / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / pharmacology; Injections, Subcutaneous; Insulin / administration & dosage; Insulin / metabolism; Insulin / pharmacology; Mice
Source: Web Of Science
Added: December 16, 2019
2019 journal article
Adipocytes as Anticancer Drug Delivery Depot
MATTER, 1(5), 1203–1214.
Source: Web Of Science
Added: April 6, 2020
2019 journal article
Advances in drug delivery for post-surgical cancer treatment
Biomaterials, 219, 119182.
author keywords: Drug delivery; Surgery; Local delivery; Cancer treatment; Immunotherapy
MeSH headings : Drug Delivery Systems / trends; Humans; Hydrogels / chemistry; Immunotherapy; Nanotechnology; Neoplasms / drug therapy; Neoplasms / surgery
Source: Crossref
Added: January 19, 2020
2019 review
Advances in transdermal insulin delivery
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70.
author keywords: Drug delivery; Transdermal delivery; Insulin; Diabetes; Iontophoresis; Electroporation; Ultrasound; Jet injection; Microneedle
MeSH headings : Administration, Cutaneous; Animals; Electroporation; Humans; Hypoglycemic Agents / administration & dosage; Insulin / administration & dosage; Iontophoresis; Microinjections; Needles; Ultrasonic Waves
Source: Web Of Science
Added: September 9, 2019
2019 journal article
Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy
NANO LETTERS, 19(8), 4879–4889.
author keywords: Drug delivery; immunotherapy; immune checkpoint blockade; bioresponsive; nanomedicine
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antineoplastic Agents, Immunological / immunology; Antineoplastic Agents, Immunological / therapeutic use; CD47 Antigen / immunology; Female; Immunotherapy; Melanoma / immunology; Melanoma / therapy; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / immunology; Reactive Oxygen Species / immunology; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: September 3, 2019
2019 journal article
Cancer Stem Cell-Platelet Hybrid Membrane-Coated Magnetic Nanoparticles for Enhanced Photothermal Therapy of Head and Neck Squamous Cell Carcinoma
Advanced Functional Materials, 29(10), 1807733.
author keywords: cancer stem cell; hybrid mimic membrane; magnetic resonance imaging; photothermal therapy; platelet
Source: Crossref
Added: January 19, 2020
2019 journal article
Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs
SCIENCE ADVANCES, 5(7).
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
Source: Web Of Science
Added: August 19, 2019
2019 review
Cysteine-rich Proteins for Drug Delivery and Diagnosis
[Review of ]. CURRENT MEDICINAL CHEMISTRY, 26(8), 1377–1388.
author keywords: Cysteine-rich protein; drug delivery; cancer diagnostics; protein-based nanoparticle; hydrogel; biomedical material
MeSH headings : Animals; Biocompatible Materials / chemistry; Cysteine / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / methods; Gold / chemistry; Humans; Hydrogels / chemistry; Nanocomposites / chemistry; Nanoparticles / chemistry; Nanotechnology / methods; Neoplasms / diagnosis; Neoplasms / drug therapy; Proteins / chemistry
Source: Web Of Science
Added: June 17, 2019
2019 journal article
Drug Delivery: A Dual‐Bioresponsive Drug‐Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade (Adv. Mater. 17/2019)
Advanced Materials, 31(17), 1970120.
Source: Crossref
Added: January 19, 2020
2019 journal article
Engineering Protein Delivery Depots for Cancer Immunotherapy
Bioconjugate Chemistry, 30(3), 515–524.
MeSH headings : Animals; Antibodies / administration & dosage; Antibodies / therapeutic use; Antigens / administration & dosage; Antigens / therapeutic use; Cancer Vaccines / administration & dosage; Cancer Vaccines / therapeutic use; Cytokines / administration & dosage; Cytokines / therapeutic use; Humans; Immunotherapy / methods; Neoplasms / therapy; Proteins / administration & dosage; Proteins / therapeutic use
Source: Crossref
Added: January 19, 2020
2019 journal article
Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot
BIOMATERIALS SCIENCE, 7(3), 860–866.
MeSH headings : Animals; Cell Line, Tumor; Cell Survival / drug effects; Cisplatin / chemistry; Cisplatin / metabolism; Cisplatin / therapeutic use; Cisplatin / toxicity; Colonic Neoplasms / drug therapy; Colonic Neoplasms / pathology; Drug Liberation; Female; Humans; Hydrogels / chemical synthesis; Hydrogels / chemistry; Mice, Inbred BALB C; Peptides / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Stilbenes / chemistry; Stilbenes / metabolism; Stilbenes / therapeutic use; Stilbenes / toxicity; Transplantation, Heterologous; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases
ACS Nano, 13(6), 6540–6549.
author keywords: plant disease; DNA extraction; microneedle patch; Phytophthora infestans; nucleic acid amplification; point-of-care diagnostics
MeSH headings : DNA Barcoding, Taxonomic / instrumentation; DNA Barcoding, Taxonomic / methods; DNA, Fungal / chemistry; DNA, Fungal / genetics; Solanum lycopersicum / microbiology; Metagenomics / instrumentation; Metagenomics / methods; Needles; Phytophthora / genetics; Phytophthora / pathogenicity; Plant Diseases / microbiology; Plant Leaves / chemistry; Plant Leaves / microbiology
Sources: Web Of Science, ORCID, Crossref
Added: July 15, 2019
2019 journal article
Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748.
author keywords: drug delivery; diabetes; glucose-responsive; insulin; insulin analog
MeSH headings : Animals; Blood Glucose / analysis; Blood Glucose / drug effects; Diabetes Mellitus, Experimental; Drug Delivery Systems / methods; Glucose Transport Proteins, Facilitative / antagonists & inhibitors; Hyperglycemia / drug therapy; Hypoglycemia / prevention & control; Hypoglycemic Agents / chemistry; Hypoglycemic Agents / pharmacology; Insulin / analogs & derivatives; Insulin / chemistry; Insulin / pharmacology; Mice
Source: Web Of Science
Added: June 17, 2019
2019 journal article
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
NATURE NANOTECHNOLOGY, 14(1), 89-+.
MeSH headings : Animals; Biocompatible Materials / chemistry; Calcium Carbonate / chemistry; Female; Fibrin / chemistry; Gels / chemistry; Humans; Immunity; Immunotherapy / methods; Luminescent Measurements; Melanoma, Experimental / pathology; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Phagocytosis
Source: Web Of Science
Added: January 21, 2019
2019 journal article
Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells
ADVANCED MATERIALS, 31(23).
author keywords: CAR T cells; cell therapy; drug delivery; immunotherapy; photothermal therapy
MeSH headings : Animals; Antigens / metabolism; Cell Line, Tumor; Chondroitin Sulfate Proteoglycans / metabolism; Combined Modality Therapy; Female; Heterografts; Humans; Hyperthermia, Induced; Immunotherapy, Adoptive / methods; Indocyanine Green / chemistry; Melanoma / pathology; Melanoma / therapy; Membrane Proteins / metabolism; Mice, SCID; Nanoparticles / chemistry; Photosensitizing Agents / chemistry; Phototherapy / methods; Polylactic Acid-Polyglycolic Acid Copolymer / chemistry; Proteoglycans / metabolism; Skin Neoplasms / pathology; Skin Neoplasms / therapy; T-Lymphocytes / metabolism; T-Lymphocytes / transplantation; Tumor Microenvironment
Source: Web Of Science
Added: July 22, 2019
2019 journal article
Platelet for drug delivery
Current Opinion in Biotechnology, 58, 81–91.
MeSH headings : Blood Platelets; Drug Delivery Systems; Hemostasis; Humans; Inflammation; Neoplasms
Source: Crossref
Added: January 19, 2020
2019 journal article
Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy
NANO RESEARCH, 12(6), 1313–1320.
author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019
2019 article
Topical and Transdermal Nanomedicines for Cancer Therapy
NANOTHERANOSTICS FOR CANCER APPLICATIONS, Vol. 5, pp. 231–251.
Source: Web Of Science
Added: October 26, 2020
2019 journal article
Topography‐Induced Cell Self‐Organization from Simple to Complex Aggregates
Small, 15(15), 1900030.
author keywords: cellular aggregate; intermolecular interaction; self-organization; topographic interaction
MeSH headings : Cell Aggregation / drug effects; Cell Line; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Cell Shape / drug effects; Cell Survival / drug effects; Cells / drug effects; Cells / metabolism; Humans; Hydrogels / pharmacology; Microscopy, Fluorescence
Source: Crossref
Added: January 19, 2020
2018 journal article
Advances in bioresponsive closed-loop drug delivery systems
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 544(2), 350–357.
author keywords: Closed-loop; Drug delivery; Bioresponsive; Glucose-responsive; Enzyme-responsive
MeSH headings : Anticoagulants / administration & dosage; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / methods; Feedback, Physiological / drug effects; Homeostasis / drug effects; Humans; Hypoglycemic Agents / administration & dosage; Thrombosis / blood; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018
2018 review
Advances in glycosylation-mediated cancer-targeted drug delivery
[Review of ]. DRUG DISCOVERY TODAY, 23(5), 1126–1138.
MeSH headings : Animals; Drug Delivery Systems; Glycosylation; Humans; Neoplasms / drug therapy
Source: Web Of Science
Added: August 6, 2018
2018 review
Advances in liquid metals for biomedical applications
[Review of ]. CHEMICAL SOCIETY REVIEWS, 47(8), 2518–2533.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Biocompatible Materials / chemistry; Biocompatible Materials / toxicity; Biosensing Techniques / methods; Drug Carriers / chemistry; Drug Carriers / toxicity; Gallium / chemistry; Humans; Metals / chemistry; Microfluidics / instrumentation; Microfluidics / methods; Nanostructures / chemistry; Neoplasms / diagnosis; Neoplasms / drug therapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / therapeutic use
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Advances in transformable drug delivery systems
BIOMATERIALS, 178, 546–558.
author keywords: Drug delivery; Stimuli-responsive; Cancer therapy; Transformable formulation
MeSH headings : Animals; Drug Delivery Systems / methods; Extracellular Space / chemistry; Humans; Intracellular Space / chemistry; Microbubbles; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasms / diagnosis; Neoplasms / pathology
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy
ACS NANO, 12(6), 5995–6005.
author keywords: salmonella; polydopamine; hypoxia targeting; photothermal therapy; malignant melanoma
MeSH headings : Animals; Antineoplastic Agents / adverse effects; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Cell Survival / drug effects; Hypoxia / metabolism; Indoles / adverse effects; Indoles / metabolism; Indoles / pharmacology; Lasers; Melanoma, Experimental / metabolism; Melanoma, Experimental / pathology; Melanoma, Experimental / therapy; Mice; Phototherapy; Polymers / adverse effects; Polymers / metabolism; Polymers / pharmacology; Salmonella / growth & development; Salmonella / metabolism; Tissue Distribution; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Biodegradable Gelatin Methacryloyl Microneedles for Transdermal Drug Delivery
Advanced Healthcare Materials, 8(3), 1801054.
author keywords: gelatin methacryloyl; microneedle; sustained release; transdermal drug delivery
MeSH headings : Administration, Cutaneous; Animals; Biocompatible Materials / chemistry; Biocompatible Materials / pharmacology; Doxorubicin / chemistry; Doxorubicin / pharmacology; Gelatin / chemistry; Gelatin / pharmacology; Hydrogels / chemistry; Hydrogels / pharmacology; Melanoma, Experimental / drug therapy; Melanoma, Experimental / metabolism; Melanoma, Experimental / pathology; Mice; Needles; Skin Neoplasms / drug therapy; Skin Neoplasms / metabolism; Skin Neoplasms / pathology
Source: Crossref
Added: January 19, 2020
2018 journal article
Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery
SMALL, 14(14).
author keywords: diabetes; drug delivery; insulin; microneedles; stimuli-responsive
MeSH headings : Animals; Drug Delivery Systems / methods; Humans; Hydrogen Peroxide / chemistry; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Mice; Oxidation-Reduction
Source: Web Of Science
Added: August 6, 2018
2018 review
Blood sampling using microneedles as a minimally invasive platform for biomedical diagnostics
[Review of ]. APPLIED MATERIALS TODAY, 13, 144–157.
author keywords: Blood sampling; Microneedle; Minimally invasive; Hemotological analysis; Point-of-care test
Source: Web Of Science
Added: December 31, 2018
2018 journal article
Cancer Immunotherapy: PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy (Adv. Mater. 22/2018)
Advanced Materials, 30(22), 1870152.
Source: Crossref
Added: December 19, 2020
2018 journal article
Cardiac cell-integrated microneedle patch for treating myocardial infarction
SCIENCE ADVANCES, 4(11).
MeSH headings : Animals; Cells, Cultured; Microtechnology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Needles; Rats; Rats, Inbred WKY; Regeneration; Stromal Cells / cytology; Stromal Cells / transplantation; Swine; Tissue Engineering / instrumentation
Sources: Web Of Science, ORCID
Added: December 31, 2018
2018 journal article
Cationic lipid-assisted nanoparticles for delivery of mRNA cancer vaccine
Biomaterials Science, 6(11), 3009–3018.
MeSH headings : Animals; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; Cancer Vaccines / chemistry; Cancer Vaccines / genetics; Cancer Vaccines / immunology; Cell Line; Dendritic Cells / cytology; Dendritic Cells / immunology; Drug Carriers / chemistry; Lipids / chemistry; Lymphoma / pathology; Lymphoma / prevention & control; Mice; Mice, Inbred C57BL; Nanoparticles / chemistry; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Messenger / immunology
Source: Crossref
Added: January 19, 2020
2018 review
Cellular Bioparticulates with Therapeutics for Cancer Immunotherapy
[Review of ]. BIOCONJUGATE CHEMISTRY, 29(3), 702–708.
MeSH headings : Animals; Antigen-Presenting Cells / cytology; Antigen-Presenting Cells / immunology; Blood Platelets / cytology; Blood Platelets / immunology; Cell Engineering / methods; Drug Delivery Systems / methods; Erythrocytes / cytology; Erythrocytes / immunology; Humans; Immunologic Factors / administration & dosage; Immunologic Factors / immunology; Immunologic Factors / therapeutic use; Immunotherapy / methods; Microbiota; Neoplasms / immunology; Neoplasms / microbiology; Neoplasms / therapy; T-Lymphocytes / cytology; T-Lymphocytes / immunology
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018
2018 journal article
Core–Shell Microneedle Gel for Self-Regulated Insulin Delivery
ACS Nano, 12(3), 2466–2473.
MeSH headings : Animals; Blood Glucose / analysis; Blood Glucose / metabolism; Delayed-Action Preparations / metabolism; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Delivery Systems / instrumentation; Enzymes, Immobilized / metabolism; Equipment Design; Humans; Hydrogels / metabolism; Hydrogen Peroxide / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / therapeutic use; Insulin / administration & dosage; Insulin / therapeutic use; Male; Mice; Mice, Inbred C57BL; Needles; Transdermal Patch
Source: Crossref
Added: January 19, 2020
2018 journal article
Delivery Strategies for Immune Checkpoint Blockade
ADVANCED HEALTHCARE MATERIALS, 7(20).
author keywords: biomaterials; cancer therapy; drug delivery; immune checkpoint blockade; immunotherapy
MeSH headings : Autoimmune Diseases / immunology; Autoimmune Diseases / therapy; Humans; Immunotherapy / methods; Neoplasms / immunology; Neoplasms / therapy
Source: Web Of Science
Added: November 19, 2018
2018 journal article
Drug-Bearing Supramolecular MMP Inhibitor Nanofibers for Inhibition of Metastasis and Growth of Liver Cancer
Advanced Science, 5(8), 1700867.
author keywords: doxorubicin; liver cancer; metastasis; matrix metalloproteinase (MMP) inhibitor; peptide drug conjugates
Source: Crossref
Added: December 19, 2020
2018 journal article
Engineering PD-1-Presenting Platelets for Cancer Immunotherapy
NANO LETTERS, 18(9), 5716–5725.
author keywords: Drug delivery; platelet; immune checkpoint blockade; immunotherapy; nanomedicine
Source: Web Of Science
Added: October 16, 2018
2018 article
Glucose-responsive insulin by molecular and physical design (vol 9, pg 937, 2017)
Bakh, N. A., Cortinas, A. B., Weiss, M. A., Langer, R. S., Anderson, D. G., Gu, Z., … Strano, M. S. (2018, January). NATURE CHEMISTRY, Vol. 10, pp. 109–109.
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Glucose-responsive oral insulin delivery for postprandial glycemic regulation
Nano Research, 12(7), 1539–1545.
author keywords: diabetes; drug delivery; glucose-responsive; insulin; nanomedicine
Source: Crossref
Added: January 19, 2020
2018 journal article
Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment
NANO LETTERS, 18(4), 2294–2303.
author keywords: Drug delivery; protein therapy; radical polymerization; cancer stem-like cells; combination cancer therapy
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Breast Neoplasms / drug therapy; Breast Neoplasms / pathology; Cell Line, Tumor; Cell Survival / drug effects; Delayed-Action Preparations / chemistry; Doxycycline / administration & dosage; Doxycycline / pharmacokinetics; Doxycycline / pharmacology; Doxycycline / therapeutic use; Drug Delivery Systems; Female; Humans; Mice; Nanostructures / chemistry; Neoplastic Stem Cells / drug effects; Ribonuclease, Pancreatic / administration & dosage; Ribonuclease, Pancreatic / pharmacokinetics; Ribonuclease, Pancreatic / pharmacology; Ribonuclease, Pancreatic / therapeutic use
Source: Web Of Science
Added: August 6, 2018
2018 journal article
In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy
SCIENCE TRANSLATIONAL MEDICINE, 10(429).
MeSH headings : Animals; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine / analogs & derivatives; Deoxycytidine / therapeutic use; Female; Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry; Immunotherapy / methods; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / metabolism; Gemcitabine
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade
Advanced Materials, 30(28), 1801527.
author keywords: checkpoint blockade; drug delivery; hydrogel; immunotherapy; stimuli responsive
MeSH headings : Gels; Humans; Immunotherapy; Melanoma; Tumor Microenvironment
Source: Crossref
Added: December 19, 2020
2018 journal article
Leverage physiology for precision medications
Nanomedicine: Nanotechnology, Biology and Medicine, 14(5), 1883–1884.
Source: Crossref
Added: January 19, 2020
2018 review
Leveraging Engineering of Cells for Drug Delivery
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 51(3), 668–677.
MeSH headings : Animals; Cell Engineering; Drug Delivery Systems; Humans
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Local generation of hydrogen for enhanced photothermal therapy
Nature Communications, 9(1).
MeSH headings : Catalysis; Hydrogen / chemistry; Nanoparticles / chemistry; Nanostructures / chemistry; Photoacoustic Techniques; Phototherapy / methods; Spectroscopy, Near-Infrared
Source: Crossref
Added: January 19, 2020
2018 journal article
Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-Assisted Polymeric Nanoparticles
ACS NANO, 12(2), 994–1005.
author keywords: CRISPR/Cas9; specific gene editing; nanomedicine; specific promoter; type 2 diabetes
MeSH headings : Animals; CRISPR-Cas Systems / genetics; Cations / chemistry; Cells, Cultured; Diabetes Mellitus, Experimental / chemically induced; Diabetes Mellitus, Experimental / genetics; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 2 / chemically induced; Diabetes Mellitus, Type 2 / genetics; Diabetes Mellitus, Type 2 / metabolism; Diet, High-Fat; Gene Editing; HEK293 Cells; Humans; Lipids / chemistry; Macrophages / chemistry; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Nanoparticles / chemistry; Netrin-1 / genetics; Netrin-1 / metabolism; Polymers / chemistry; RAW 264.7 Cells
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Nanomedicine for obesity treatment
Science China Life Sciences, 61(4), 373–379.
author keywords: drug delivery; nanomedicine; obesity; browning; fat absorption; energy expenditure
MeSH headings : Anti-Obesity Agents / pharmacology; Anti-Obesity Agents / therapeutic use; Drug Delivery Systems / trends; Energy Metabolism / drug effects; Humans; Models, Biological; Nanomedicine; Obesity / drug therapy; Obesity / metabolism
Source: Crossref
Added: January 19, 2020
2018 journal article
PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy
ADVANCED MATERIALS, 30(22).
author keywords: cancer immunotherapy; cell therapy; drug delivery; immune checkpoint blockade; nanomedicine
MeSH headings : Humans; Immunotherapy; Lymphocytes, Tumor-Infiltrating; Neoplasms / therapy; Programmed Cell Death 1 Receptor; T-Lymphocytes; Tumor Microenvironment
Source: Web Of Science
Added: August 6, 2018
2018 journal article
PDT-Driven Highly Efficient Intracellular Delivery and Controlled Release of CO in Combination with Sufficient Singlet Oxygen Production for Synergistic Anticancer Therapy
Advanced Functional Materials, 28(41), 1804324.
author keywords: carbon monoxide; combination therapy; nanogels; peptide dendrimers; photodynamic therapy
Source: Crossref
Added: January 19, 2020
2018 review
Polymeric microneedles for transdermal protein delivery
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 127, 106–118.
author keywords: Drug delivery; Transdermal; Microneedle; Protein delivery; Vaccine
MeSH headings : Administration, Cutaneous; Drug Delivery Systems; Humans; Microinjections; Needles; Polymers / chemistry; Proteins / administration & dosage; Proteins / metabolism; Proteins / pharmacokinetics; Skin / metabolism
Source: Web Of Science
Added: August 6, 2018
2018 journal article
ROS-Responsive Microneedle Patch for Acne Vulgaris Treatment
Advanced Therapeutics, 1(3), 1800035.
author keywords: acne vulgaris; drug delivery; microneedle patch; stimuli responsive
Source: Crossref
Added: December 19, 2020
2018 journal article
ROS-Responsive Microneedle Patch for Acne Vulgaris Treatment (Adv. Therap. 3/2018)
Advanced Therapeutics, 1(3), 1870006.
Source: Crossref
Added: December 19, 2020
2018 journal article
Strategies of Combination Drug Delivery for Immune Checkpoint Blockades
Advanced Healthcare Materials, 1801099.
author keywords: cancer immunity circles; cancer immunotherapy; combination delivery; drug delivery; immune checkpoint blockades
MeSH headings : Animals; Antigens, Neoplasm / immunology; Antigens, Neoplasm / therapeutic use; Drug Delivery Systems; Humans; Immunotherapy; Lymphocyte Activation / drug effects; Neoplasms / immunology; Neoplasms / pathology; Neoplasms / therapy; T-Lymphocytes, Cytotoxic / immunology; T-Lymphocytes, Cytotoxic / pathology
Source: Crossref
Added: January 19, 2020
2018 journal article
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases
Nature Communications, 9(1).
MeSH headings : Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins / metabolism; CRISPR-Cas Systems; Calcium-Binding Proteins / metabolism; Caspase Activation and Recruitment Domain; Female; Gene Editing; Genetic Therapy; Inflammasomes / genetics; Inflammation / therapy; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Peritonitis / immunology; Protein Conformation
Source: Crossref
Added: January 19, 2020
2018 article
The potential of a microneedle patch for reducing obesity
EXPERT OPINION ON DRUG DELIVERY, Vol. 15, pp. 431–433.
author keywords: Obesity; browning; microneedle; intradermal delivery
Source: Web Of Science
Added: August 6, 2018
2018 article
Towards Enhancing Skin Drug Delivery
Gu, Z., & Chen, X. (2018, March 1). ADVANCED DRUG DELIVERY REVIEWS, Vol. 127, pp. 1–2.
MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems; Humans; Skin / metabolism
Source: Web Of Science
Added: August 6, 2018
2017 journal article
A melanin-mediated cancer immunotherapy patch
SCIENCE IMMUNOLOGY, 2(17).
MeSH headings : Animals; Cancer Vaccines / immunology; Cancer Vaccines / metabolism; Cell Line, Tumor; Dendritic Cells / immunology; Dendritic Cells / metabolism; Female; Immunotherapy / instrumentation; Immunotherapy / methods; Infrared Rays; Kaplan-Meier Estimate; Melanins / immunology; Melanins / metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Needles; Neoplasms, Experimental / immunology; Neoplasms, Experimental / pathology; Neoplasms, Experimental / therapy; Transdermal Patch; Tumor Burden / immunology
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Anaerobe-Inspired Anticancer Nanovesicles
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(10), 2588–2593.
author keywords: drug delivery; nanomedicines; photodynamic therapy
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Death / drug effects; Cell Proliferation / drug effects; Clostridium / chemistry; Clostridium / metabolism; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Hypoxia / metabolism; Imidazoles / chemistry; Imidazoles / pharmacology; Nanoparticles / chemistry; Prodrugs / chemistry; Prodrugs / pharmacology; Salmonella / chemistry; Salmonella / metabolism; Tirapazamine / chemistry; Tirapazamine / pharmacology
Source: Web Of Science
Added: August 6, 2018
2017 review
Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
[Review of ]. THERANOSTICS, 7(14), 3504–3516.
author keywords: artificial immune cells; lymphoid organs
MeSH headings : Animals; Antigen-Presenting Cells / immunology; Artificial Cells / chemistry; Artificial Cells / immunology; Biomimetic Materials / chemistry; Humans; Lymphoid Tissue / cytology; Lymphoid Tissue / immunology
Source: Web Of Science
Added: August 6, 2018
2017 review
Bioresponsive materials
[Review of ]. NATURE REVIEWS MATERIALS, 2(1).
Source: Web Of Science
Added: August 6, 2018
2017 review
Bioresponsive transcutaneous patches
[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 48, 28–32.
MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / methods; Drug Monitoring / methods; Humans; Needles; Skin; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018
2017 review
Conjugated polymer nanomaterials for theranostics
[Review of ]. ACTA PHARMACOLOGICA SINICA, 38(6), 764–781.
author keywords: conjugated polymer; theranostics; biomedical imaging; photodynamic therapy; photothermal therapy; stimuli; responsive drug delivery
MeSH headings : Drug Delivery Systems; Nanostructures / chemistry; Photochemotherapy; Polymers / chemistry; Theranostic Nanomedicine
Source: Web Of Science
Added: August 6, 2018
2017 review
Engineering platelet-mimicking drug delivery vehicles
[Review of ]. FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING, 11(4), 624–632.
author keywords: drug delivery; platelets; nanomedicine; bio-inspired; biomimetic
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species
NANO LETTERS, 17(2), 928–937.
author keywords: Drug delivery; cisplatin; iron oxide; Fenton's reaction; reactive oxygen species
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Line, Tumor; Cell Survival; Cisplatin / chemistry; Cisplatin / pharmacology; Cisplatin / therapeutic use; Drug Carriers; Drug Liberation; Electromagnetic Fields; Ferric Compounds / chemistry; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Metal Nanoparticles / chemistry; Mice, Inbred BALB C; Oxidation-Reduction; Particle Size; Reactive Oxygen Species / metabolism; Surface Properties; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Enhanced Endosomal Escape by Light-Fueled Liquid-Metal Transformer
NANO LETTERS, 17(4), 2138–2145.
author keywords: Drug delivery; liquid metal; stimuli-responsive; morphological transformation; endosomal escape
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Glucose-responsive insulin by molecular and physical design
NATURE CHEMISTRY, 9(10), 937–943.
MeSH headings : Diabetes Mellitus / drug therapy; Diabetes Mellitus / metabolism; Glucose / metabolism; Humans; Insulin / metabolism; Insulin / therapeutic use; Models, Biological
Source: Web Of Science
Added: August 6, 2018
2017 journal article
H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery
ACS NANO, 11(1), 613–620.
author keywords: drug delivery; vesicles; polymersome; glucose-responsive; insulin; diabetes
MeSH headings : Animals; Diabetes Mellitus, Experimental / chemically induced; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems / methods; Glucose / analysis; Glucose / metabolism; Glucose Oxidase / metabolism; Hydrogen Peroxide / chemistry; Hypoglycemia / drug therapy; Insulin / administration & dosage; Insulin / chemistry; Insulin / pharmacology; Kinetics; Male; Mice; Mice, Inbred C57BL; Polymers / chemical synthesis; Polymers / chemistry; Streptozocin; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery
NANO LETTERS, 17(2), 733–739.
author keywords: Drug delivery; diabetes; insulin; glucose-responsive; hypoxia-sensitive; H2O2-sensitive
MeSH headings : Animals; Blood Glucose / metabolism; Cell Hypoxia; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Carriers / chemistry; Drug Liberation; Glucose / metabolism; Glucose Oxidase / metabolism; HeLa Cells; Humans; Hydrogen Peroxide / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Insulin / administration & dosage; Insulin / chemistry; Male; Mice, Inbred C57BL; Nitroimidazoles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
Source: Web Of Science
Added: August 6, 2018
2017 journal article
In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy
Nature Biomedical Engineering, 1(2).
Source: Crossref
Added: December 19, 2020
2017 journal article
Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody
Advanced Materials, 29(15).
Source: Crossref
Added: December 19, 2020
2017 journal article
Injectable Thermosensitive Polypeptide-Based CDDP-Complexed Hydrogel for Improving Localized Antitumor Efficacy
Biomacromolecules, 18(12), 4341–4348.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Biocompatible Materials / chemistry; Biodegradable Plastics / chemistry; Cell Line, Tumor; Cisplatin / chemistry; Cisplatin / pharmacology; Drug Carriers / chemistry; Female; Glutamic Acid / chemistry; HeLa Cells; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry; Injections / methods; MCF-7 Cells; Mice; Mice, Inbred BALB C; Peptides / chemistry; Polyethylene Glycols / chemistry; Rats; Rats, Sprague-Dawley
Source: Crossref
Added: December 19, 2020
2017 journal article
Inside Cover: Anaerobe-Inspired Anticancer Nanovesicles (Angew. Chem. Int. Ed. 10/2017)
Angewandte Chemie International Edition, 56(10), 2516–2516.
Source: Crossref
Added: December 19, 2020
2017 journal article
Insulin-Responsive Glucagon Delivery for Prevention of Hypoglycemia
Small, 13(19), 1603028.
MeSH headings : Animals; Blood Glucose / metabolism; Glucagon / metabolism; Humans; Hypoglycemia / metabolism; Insulin / therapeutic use; Mice
Source: Crossref
Added: December 19, 2020
2017 journal article
Insulin-responsive glucagon delivery for prevention of hypoglycemia
Small (Weinheim An Der Bergstrasse, Germany), 13(19).
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Investigation and intervention of autophagy to guide cancer treatment with nanogels
NANOSCALE, 9(1), 150–163.
MeSH headings : Animals; Autophagy; Chloroquine / administration & dosage; Doxorubicin / administration & dosage; Drug Delivery Systems; Endocytosis; Endosomes; Exocytosis; Female; Gels; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms, Experimental / drug therapy; Rhodamines; Xenograft Model Antitumor Assays; rab GTP-Binding Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018
2017 article
KIDNEY PHYSIOLOGYA size bandpass filter
Lu, Y., & Gu, Z. (2017, November). NATURE NANOTECHNOLOGY, Vol. 12, pp. 1023–1025.
MeSH headings : Animals; Glomerular Filtration Rate; Humans; Kidney Glomerulus / metabolism; Nanoparticles; Particle Size
Source: Web Of Science
Added: August 6, 2018
2017 journal article
KO of 5-InsP(7) kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(45), 11968–11973.
author keywords: bioenergetics; signaling; inositol pyrophosphates
MeSH headings : Adenosine Triphosphate / metabolism; CRISPR-Cas Systems; Cell Line, Tumor; Colonic Neoplasms / metabolism; Cyclin-Dependent Kinase Inhibitor p21 / biosynthesis; G1 Phase Cell Cycle Checkpoints / genetics; Gene Knockout Techniques; Glycolysis / genetics; Glycolysis / physiology; HCT116 Cells; HEK293 Cells; Humans; Inositol Phosphates / metabolism; Mitochondria / metabolism; Phosphotransferases (Phosphate Group Acceptor) / genetics; Phosphotransferases (Phosphate Group Acceptor) / metabolism; Signal Transduction; Tumor Suppressor Protein p53 / biosynthesis
Source: Web Of Science
Added: August 6, 2018
2017 review
LEVERAGING PHYSIOLOGY FOR PRECISION DRUG DELIVERY
[Review of ]. PHYSIOLOGICAL REVIEWS, 97(1), 189–225.
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Leveraging H2O2Levels for Biomedical Applications
Advanced Biosystems, 1(9), 1700084.
author keywords: diagnosis; drug delivery; H2O2-responsive; oxidation-responsive; polymers
Source: Crossref
Added: November 30, 2020
2017 journal article
Local delivery of checkpoints antibodies
HUMAN VACCINES & IMMUNOTHERAPEUTICS, 13(1), 245–248.
author keywords: biomaterials; cancer immunotherapy; drug delivery; immune checkpoint inhibitors; microneedle
MeSH headings : Antibodies / administration & dosage; Biomedical Research / trends; Humans; Immunologic Factors / administration & dosage; Immunotherapy / methods; Molecular Targeted Therapy / methods; Neoplasms / immunology; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment
ACS NANO, 11(9), 9223–9230.
author keywords: drug delivery; microneedle patch; obesity; browning agent; adipose tissue
MeSH headings : Adipocytes, White / drug effects; Adipose Tissue, White / drug effects; Animals; Anti-Obesity Agents / administration & dosage; Anti-Obesity Agents / therapeutic use; Drug Delivery Systems / instrumentation; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / therapeutic use; Male; Mice, Inbred C57BL; Obesity / drug therapy; Rosiglitazone / administration & dosage; Rosiglitazone / therapeutic use; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018
2017 review
Photoacoustic Drug Delivery
[Review of ]. SENSORS, 17(6).
author keywords: photoacoustic imaging; drug delivery; chemotherapy; photothermal therapy
MeSH headings : Drug Delivery Systems; Humans; Optical Imaging; Photoacoustic Techniques; Spectrum Analysis; Theranostic Nanomedicine
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Red Blood Cells for Drug Delivery
Small Methods, 1(12), 1700270.
author keywords: interface engineering; layer-by-layer assembly; multilayer thin films; optoelectronic devices
Source: Crossref
Added: December 19, 2020
2017 journal article
Red Blood Cells for Glucose-Responsive Insulin Delivery
ADVANCED MATERIALS, 29(18).
MeSH headings : Erythrocytes; Glucose; Insulin
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy
ADVANCED MATERIALS, 29(13).
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Biomimetic Materials / chemistry; Blood Vessels / drug effects; Blood Vessels / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cells, Cultured; Dextrans / chemistry; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice, Nude; Microtubules / enzymology; Microtubules / metabolism; Nanostructures / chemistry; Neoplasm Transplantation; Neoplasms / blood supply; Neoplasms / drug therapy; Neoplasms / metabolism; Oligopeptides / chemistry; Paclitaxel / administration & dosage; Paclitaxel / pharmacokinetics; Tumor Necrosis Factor-alpha / chemistry; Tumor Necrosis Factor-alpha / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Smart materials and systems as artificial pancreas for diabetes treatment
Smart Materials for Tissue Engineering: Applications, 25, 358–381.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Stimuli-Responsive Polymersomes for Biomedical Applications
BIOMACROMOLECULES, 18(3), 649–673.
MeSH headings : Biomimetic Materials / chemistry; Diagnostic Imaging; Drug Carriers / chemistry; Drug Delivery Systems; Hydrogen-Ion Concentration; Membranes, Artificial; Nanoparticles / chemistry; Polymers / chemistry; Reactive Oxygen Species / metabolism
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Synthetic beta cells for fusion-mediated dynamic insulin secretion
Nature Chemical Biology, 14(1), 86–93.
MeSH headings : Animals; Artificial Cells; Biomimetic Materials / chemistry; Blood Glucose / analysis; Cell Engineering / methods; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Hydrogen-Ion Concentration; Insulin / blood; Insulin / metabolism; Insulin Secretion; Insulin-Secreting Cells / metabolism; Male; Membrane Fusion; Mice, Inbred C57BL
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook
ADVANCED MATERIALS, 29(29).
author keywords: biomaterials; cancer immunotherapy; cell therapy; drug delivery
MeSH headings : Animals; Antigen-Presenting Cells / cytology; Antigen-Presenting Cells / metabolism; Antigens / genetics; Antigens / immunology; Antigens / metabolism; Biocompatible Materials / chemistry; Cell- and Tissue-Based Therapy; Humans; Immunologic Factors / metabolism; Immunologic Factors / therapeutic use; Immunotherapy; Nanostructures / chemistry; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018
2017 review
Tailoring non-viral delivery vehicles for transporting genome-editing tools
[Review of ]. Science China-Materials, 60(6), 511–515.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Thrombin-responsive transcutaneous patch for auto-anticoagulant regulation
Advanced Materials, 29(4).
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Ultrasound-triggered noninvasive regulation of blood glucose levels using microgels integrated with insulin nanocapsules
Nano Research, 10(4), 1393–1402.
author keywords: controlled drug delivery; focused ultrasound; diabetes; nanocapsule; microgel
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 article
ATP-Responsive Drug Delivery Systems
Sun, W., & Gu, Z. (2016, March 3). EXPERT OPINION ON DRUG DELIVERY, Vol. 13, pp. 311–314.
MeSH headings : Adenosine Triphosphate / metabolism; Drug Carriers / chemistry; Drug Delivery Systems; Humans
Source: Web Of Science
Added: August 6, 2018
2016 journal article
ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging
THERANOSTICS, 6(7), 1053–1064.
author keywords: drug delivery; nanomedicine; stimuli-responsive; ATP-responsive; theranostics; conjugated polymers
MeSH headings : Adenosine Triphosphate / metabolism; Antineoplastic Agents / administration & dosage; Boronic Acids / metabolism; Doxorubicin / administration & dosage; Drug Carriers / administration & dosage; Hep G2 Cells; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Nanoparticles / administration & dosage; Optical Imaging / methods; Theranostic Nanomedicine / methods
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Anticancer Therapy: Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy (Adv. Mater. 17/2016)
Advanced Materials, 28(17), 3226–3226.
Source: Crossref
Added: April 3, 2022
2016 conference paper
Cell membrane-mediated anticancer drug delivery
Nanotechnology: delivering on the promise, vol 2, 1224, 197–211.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Drug Delivery: Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery (Adv. Mater. 16/2016)
Advanced Materials, 28(16), 3223–3223.
Source: Crossref
Added: December 17, 2020
2016 journal article
Dual targeted nanocarrier for brain ischemic stroke treatment
JOURNAL OF CONTROLLED RELEASE, 233, 64–71.
author keywords: Stroke; Stroke homing peptide; Dual-targeting liposomes; ZL006; Neuroprotection
Source: Web Of Science
Added: August 6, 2018
2016 article
Elastic drug delivery: could treatments be triggered by patient movement?
NANOMEDICINE, Vol. 11, pp. 323–325.
author keywords: drug delivery; mechanical-responsive; nanoparticle; wearable devices
MeSH headings : Drug Delivery Systems; Elasticity; Humans; Movement; Patients
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus
ADVANCED MATERIALS, 28(43), 9573-+.
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Enhanced Antiglioblastoma Efficacy of Neovasculature and Glioma Cells Dual Targeted Nanoparticles
MOLECULAR PHARMACEUTICS, 13(10), 3506–3517.
author keywords: glioma; antineovasculature; dual-targeted nanoparticle; drug delivery; paclitaxel
MeSH headings : Animals; Antineoplastic Agents, Phytogenic / chemistry; Antineoplastic Agents, Phytogenic / therapeutic use; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma / drug therapy; Glioma / drug therapy; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles / chemistry; Paclitaxel / chemistry; Paclitaxel / therapeutic use; Polyesters / chemistry; Polyethylene Glycols / chemistry; Rats
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody
NANO LETTERS, 16(4), 2334–2340.
author keywords: Anti-PD-1; cancer immunotherapy; microneedle patch; melanoma; drug delivery
MeSH headings : Animals; Antibodies, Neoplasm / immunology; Antibodies, Neoplasm / pharmacology; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Immunotherapy / instrumentation; Immunotherapy / methods; Mice; Needles; Programmed Cell Death 1 Receptor / immunology; Skin Neoplasms / immunology; Skin Neoplasms / pathology; Skin Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Hypoxia-Sensitive Materials for Biomedical Applications
ANNALS OF BIOMEDICAL ENGINEERING, 44(6), 1931–1945.
author keywords: Hypoxia-responsive; Drug delivery; Bioimaging; Hypoxia inducible factor-1; Bioreductive molecule
MeSH headings : Animals; Cell Hypoxia; Humans; Hypoxia-Inducible Factor 1 / metabolism; Tissue Scaffolds / chemistry
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody
ADVANCED MATERIALS, 28(40), 8912–8920.
MeSH headings : Adjuvants, Immunologic; Animals; Antibodies; CpG Islands; Immunotherapy; Inflammation; Mice; Neoplasms / therapy; Programmed Cell Death 1 Receptor / immunology
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Internalized compartments encapsulated nanogels for targeted drug delivery
NANOSCALE, 8(17), 9178–9184.
MeSH headings : Doxorubicin / administration & dosage; Drug Delivery Systems; Ferrous Compounds; Hyaluronic Acid; Nanoparticles; Silicon Dioxide
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Introduction to special issue on “Responsive Materials and Systems: Toward Smart and Precision Medications”
Introduction to special issue on “Responsive Materials and Systems: Toward Smart and Precision Medications.” Bioengineering & Translational Medicine, 1(3), 235–236.
Source: Crossref
Added: August 16, 2021
2016 journal article
Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy
ADVANCED MATERIALS, 28(17), 3313–3320.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Hypoxia; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Doxorubicin / therapeutic use; Drug Carriers / chemistry; HeLa Cells; Humans; Hydrogen-Ion Concentration; Light; Mice; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles / chemistry; Neoplasms / diagnostic imaging; Neoplasms / drug therapy; Neoplasms / pathology; Optical Imaging; Polyvinyl Alcohol / chemistry; Singlet Oxygen / chemistry; Singlet Oxygen / metabolism; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018
2016 review
Mechanical Force-Triggered Drug Delivery
[Review of ]. CHEMICAL REVIEWS, 116(19), 12536–12563.
MeSH headings : Animals; Drug Carriers / chemistry; Drug Carriers / pharmacology; Drug Delivery Systems / methods; Liposomes / chemistry; Liposomes / pharmacology; Magnetic Phenomena; Mechanical Phenomena; Microbubbles; Nanoparticles / chemistry; Ultrasonic Waves
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery
Advanced Materials, 28(16), 3115–3121.
MeSH headings : Animals; Blood Glucose / analysis; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Experimental / pathology; Insulin / metabolism; Insulin Secretion; Islets of Langerhans / metabolism; Mice; Needles; Time Factors
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Photo-Cross-Linked Scaffold with Kartogenin-Encapsulated Nanoparticles for Cartilage Regeneration
ACS NANO, 10(1), 1292–1299.
author keywords: drug delivery; tissue engineering; hydrogel; regenerative medicine; nanoparticles
Source: Web Of Science
Added: August 6, 2018
2016 review
Recent advances of cocktail chemotherapy by combination drug delivery systems
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 98, 19–34.
author keywords: Chemotherapy; Combination; Cancer; Nanocarriers; Drug delivery
MeSH headings : Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Drug Delivery Systems; Humans; Nanoparticles / administration & dosage; Nanoparticles / therapeutic use; Neoplasms / drug therapy
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Stimuli-responsive delivery of therapeutics for diabetes treatment
Bioengineering & Translational Medicine, 1(3), 323–337.
Source: Crossref
Added: August 16, 2021
2016 journal article
Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors
ACS NANO, 10(9), 8956–8963.
author keywords: drug delivery; immunotherapy; anti-PD1; IDO; microneedle
MeSH headings : Animals; Cell Cycle Checkpoints / drug effects; Drug Delivery Systems; Immunosuppression Therapy; Immunotherapy / methods; Indoleamine-Pyrrole 2,3,-Dioxygenase / therapeutic use; Melanoma / therapy; Programmed Cell Death 1 Receptor / therapeutic use; Skin Neoplasms / therapy; Tumor Microenvironment
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation
Advanced Materials, 29(4), 1604043.
MeSH headings : Anticoagulants; Blood Coagulation; Heparin; Skin; Thrombin / administration & dosage
Sources: Crossref, ORCID
Added: January 19, 2020
2016 journal article
Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine
BIOMATERIALS, 96, 1–10.
author keywords: Cancer; Protein delivery; DNA structures; Cytokine; Nanomedicine
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Tumor Microenvironment-Mediated Construction and Deconstruction of Extracellular Drug-Delivery Depots
NANO LETTERS, 16(2), 1118–1126.
author keywords: Drug delivery; stimuli-responsive; tumor microenvironment; apoptosis; antiangiogenesis
MeSH headings : Angiogenesis Inhibitors / administration & dosage; Angiogenesis Inhibitors / chemistry; Animals; Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Cell Line, Tumor; Cell Membrane Permeability / drug effects; Drug Delivery Systems; Endosomes / drug effects; Gene Transfer Techniques; Humans; Hyaluronoglucosaminidase / biosynthesis; Hyaluronoglucosaminidase / chemistry; Mice; Snake Venoms / administration & dosage; Snake Venoms / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; Tumor Microenvironment / drug effects; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery
MATERIALS TODAY, 19(5), 274–283.
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Versatile Protein Nanogels Prepared by In Situ Polymerization
MACROMOLECULAR CHEMISTRY AND PHYSICS, 217(3), 333–343.
author keywords: drug delivery; in situ polymerization; nanogels; protein; stimuli-responsive
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment
NANOSCALE, 7(28), 12096–12103.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Drug Screening Assays, Antitumor; Gold / chemistry; Gold / pharmacology; HeLa Cells; Humans; Infrared Rays; Nanotubes / chemistry; Neoplasms / drug therapy; Photochemotherapy
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
A temperature microsensor for measuring laser-induced heating in gold nanorods
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(3), 719–725.
author keywords: Microsensor; Gold nanorods; Temperature; Nanoparticles; Microfluidics
MeSH headings : Chemistry Techniques, Analytical / instrumentation; Chemistry Techniques, Analytical / methods; Equipment Design; Gold; Heating; Hot Temperature; Lasers; Microtechnology; Nanotubes / analysis
Source: Web Of Science
Added: August 6, 2018
2015 journal article
ATP-responsive DNA-graphene hybrid nanoaggregates for anticancer drug delivery
BIOMATERIALS, 50, 67–74.
author keywords: ATP responsive; Graphene oxide; DNA; Drug delivery; Nanomedicine
MeSH headings : Adenosine Triphosphate / pharmacology; Antineoplastic Agents / pharmacology; Cell Death / drug effects; DNA, Single-Stranded / chemistry; Doxorubicin / pharmacology; Drug Delivery Systems; Endocytosis / drug effects; Graphite / chemistry; HeLa Cells; Humans; Intracellular Space / metabolism; Nanoparticles / chemistry; Particle Size; Spectrometry, Fluorescence
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Accelerating the Translation of Nanomaterials in Biomedicine
ACS NANO, 9(7), 6644–6654.
MeSH headings : Nanomedicine / methods; Nanomedicine / trends; Translational Research, Biomedical
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Anticancer Platelet-Mimicking Nanovehicles
ADVANCED MATERIALS, 27(44), 7043-+.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Biomimetic Materials / chemistry; Blood Platelets / cytology; Cell Line, Tumor; Cell Membrane / chemistry; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Humans; Intracellular Space / metabolism; Mice; Nanomedicine / methods; Nanostructures / chemistry; TNF-Related Apoptosis-Inducing Ligand / chemistry; TNF-Related Apoptosis-Inducing Ligand / metabolism
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Characterization of a novel N-acetylneuraminic acid lyase favoring N-acetylneuraminic acid synthesis
SCIENTIFIC REPORTS, 5.
MeSH headings : Amino Acid Sequence; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Biocatalysis; Cloning, Molecular; Corynebacterium glutamicum / chemistry; Corynebacterium glutamicum / classification; Corynebacterium glutamicum / enzymology; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression; Hexosamines / metabolism; Hydro-Lyases / chemistry; Hydro-Lyases / classification; Hydro-Lyases / genetics; Hydro-Lyases / metabolism; Kinetics; Molecular Sequence Data; N-Acetylneuraminic Acid / biosynthesis; Oxo-Acid-Lyases / chemistry; Oxo-Acid-Lyases / genetics; Oxo-Acid-Lyases / metabolism; Phylogeny; Pyruvic Acid / metabolism; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Sequence Alignment; Substrate Specificity
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Confinement-induced nanocrystal alignment of conjugated polymer by the soft-stamped nanoimprint lithography
CHINESE PHYSICS B, 24(10).
author keywords: conjugated polymer; soft lithography; nanocrystalline material; x-ray technique
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Cover Picture: Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing (Angew. Chem. Int. Ed. 41/2015)
Angewandte Chemie International Edition, 54(41), 11877–11877.
Source: Crossref
Added: February 24, 2020
2015 journal article
Drug Delivery: Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene (Adv. Mater. 6/2015)
Advanced Materials, 27(6), 958–958.
Sources: Crossref, ORCID
Added: March 26, 2021
2015 review
Engineering DNA scaffolds for delivery of anticancer therapeutics
[Review of ]. BIOMATERIALS SCIENCE, 3(7), 1018–1024.
MeSH headings : DNA / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / methods; Engineering; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / therapeutic use; Nanostructures / chemistry; Nanostructures / therapeutic use; Nanotechnology / methods; Neoplasms / chemistry; Neoplasms / drug therapy; Nucleic Acids / chemistry
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Engineering Synthetic Insulin-Secreting Cells Using Hyaluronic Acid Microgels Integrated with Glucose-Responsive Nanoparticles
CELLULAR AND MOLECULAR BIOENGINEERING, 8(3), 445–454.
author keywords: Insulin delivery; Diabetes; Glucose responsive; Bio-inspired; Hyaluronic acid; Dextran
Source: Web Of Science
Added: August 6, 2018
2015 review
Glucose-responsive synthetic closed-loop insulin delivery systems
[Review of ]. Progress in Chemistry, 27(1), 11–26.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Hybrid Fe3O4-Poly(acrylic acid) Nanogels for Theranostic Cancer Treatment
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 11(5), 771–779.
author keywords: Hybrid Magnetic Nanogels; In Situ Co-Precipitation; MRI Imaging; High Drug Loading Capacity; Tumor Target
MeSH headings : Acrylic Resins / chemistry; Acrylic Resins / therapeutic use; Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Delivery Systems; Ferric Compounds / chemistry; Ferric Compounds / therapeutic use; Humans; Magnetic Resonance Imaging; Materials Testing; Mice; Mice, Inbred ICR; Nanogels; Nanoparticles / chemistry; Nanoparticles / therapeutic use; Neoplasms / drug therapy; Neoplasms / metabolism; Neoplasms / pathology; Polyethylene Glycols / chemical synthesis; Polyethylene Glycols / chemistry; Polyethylene Glycols / therapeutic use; Polyethyleneimine / chemical synthesis; Polyethyleneimine / chemistry; Polyethyleneimine / therapeutic use; Tumor Cells, Cultured
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.
author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
MeSH headings : Animals; Blood Glucose / analysis; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Hypoxia / metabolism; Insulin / administration & dosage; Insulin / chemistry; Insulin / metabolism; Male; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidation-Reduction; Reproducibility of Results
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Nanomedicine: Anticancer Platelet-Mimicking Nanovehicles (Adv. Mater. 44/2015)
Advanced Materials, 27(44), 7014–7014.
Source: Crossref
Added: April 3, 2022
2015 journal article
Polypyrrole-Based Implantable Electroactive Pump for Controlled Drug Microinjection
ACS APPLIED MATERIALS & INTERFACES, 7(27), 14563–14568.
author keywords: polypyrrole; electroactuator; implantable; controlled drug delivery; diabetes
MeSH headings : Electric Conductivity; Electrodes; Equipment Design; Equipment Failure Analysis; Infusion Pumps, Implantable; Micro-Electrical-Mechanical Systems / instrumentation; Microfluidics / instrumentation; Microinjections / instrumentation; Polymers / chemistry; Pyrroles / chemistry
Source: Web Of Science
Added: August 6, 2018
2015 review
Programmable nanomedicine: synergistic and sequential drug delivery systems
[Review of ]. NANOSCALE, 7(8), 3381–3391.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Cell Line, Tumor; DNA / chemistry; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Resistance, Neoplasm; Humans; Microscopy, Electron, Transmission; Nanomedicine / methods; Nanoparticles / chemistry; Neoplasms / drug therapy; Neoplasms / pathology
Source: Web Of Science
Added: August 6, 2018
2015 review
Recent advances in nanotechnology for diabetes treatment
[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 7(4), 548–564.
MeSH headings : Diabetes Mellitus / therapy; Electrochemical Techniques; Glucose / analysis; Humans; Insulin / administration & dosage; Insulin Infusion Systems; Nanotechnology / trends
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
Angewandte Chemie International Edition, 54(41), 12029–12033.
author keywords: CRISPR-Cas9; DNA; drug delivery; genome editing; nanoparticles
MeSH headings : Animals; CRISPR-Associated Proteins / administration & dosage; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / administration & dosage; DNA / chemistry; DNA / genetics; Green Fluorescent Proteins / genetics; Humans; Mice, Nude; Nanoparticles / chemistry; Neoplasms / genetics; Neoplasms / therapy; RNA, Guide, Kinetoplastida / administration & dosage; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; Streptococcus pyogenes / chemistry; Streptococcus pyogenes / genetics
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 article
Spatiotemporal drug delivery using laser-generated-focused ultrasound system
Di, J., Kim, J., Hu, Q., Jiang, X., & Gu, Z. (2015, December 28). JOURNAL OF CONTROLLED RELEASE, Vol. 220, pp. 592–599.
author keywords: Drug delivery; Photoacoustic; Nanoparticles; Microgels; Stimuli responsive
MeSH headings : Alginates / chemistry; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / chemistry; Cell Proliferation / drug effects; Cell Survival / drug effects; Chemistry, Pharmaceutical; Ciprofloxacin / administration & dosage; Ciprofloxacin / chemistry; Delayed-Action Preparations; Dimethylpolysiloxanes / chemistry; Disk Diffusion Antimicrobial Tests; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers; Equipment Design; Escherichia coli / drug effects; Escherichia coli / growth & development; Gels; Glucuronic Acid / chemistry; HeLa Cells; Hexuronic Acids / chemistry; Humans; Kinetics; Lactic Acid / chemistry; Lasers; Nanoparticles; Photoacoustic Techniques; Polyglycolic Acid / chemistry; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Soot / chemistry; Spheroids, Cellular; Technology, Pharmaceutical / instrumentation; Technology, Pharmaceutical / methods; Transducers; Ultrasonic Waves; Ultrasonics / instrumentation; Ultrasonics / methods
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots
ACS NANO, 9(9), 9407–9415.
author keywords: drug delivery; wearable devices; stimuli-responsive; nanoparticles; microdepots
MeSH headings : Animals; Drug Delivery Systems; Drug Liberation; Elastomers / chemistry; Elastomers / pharmacology; Mice; Nanoparticles / chemistry; Polymers / chemistry; Polymers / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Transformable liquid-metal nanomedicine
NATURE COMMUNICATIONS, 6(1).
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Female; Gallium / chemistry; Humans; Indium / chemistry; Metal Nanoparticles / chemistry; Mice; Mice, Inbred BALB C; Nanomedicine / instrumentation; Nanomedicine / methods; Neoplasms / drug therapy
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
ATP-triggered anticancer drug delivery
NATURE COMMUNICATIONS, 5.
MeSH headings : Adenosine Triphosphate / chemistry; Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Apoptosis; Cell Line; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Carriers / chemistry; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles / chemistry; Polymers / chemistry; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Advances in Anticancer Protein Delivery using Micro-/Nanoparticles
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 31(12), 1204–1222.
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Bio-lnspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin
BIOMACROMOLECULES, 15(10), 3495–3502.
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Drug Delivery Systems / methods; Gluconates / chemistry; Glucose / administration & dosage; Glucose / chemistry; Glucose Oxidase / metabolism; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Male; Mice; Mice, Inbred C57BL; Polymers / administration & dosage; Polymers / chemistry
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Clickable Protein Nanocapsules for Targeted Delivery of Recombinant p53 Protein
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(43), 15319–15325.
MeSH headings : Amino Acid Sequence; Azides / chemistry; Cell Survival / drug effects; Click Chemistry; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Carriers / toxicity; Drug Liberation; Gonadotropin-Releasing Hormone / chemistry; HeLa Cells; Humans; Ligands; Nanocapsules / chemistry; Nanocapsules / toxicity; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Polyethylene Glycols / chemistry; Recombinant Proteins / chemistry; Single-Chain Antibodies / chemistry; Single-Chain Antibodies / metabolism; Surface Properties; Tumor Suppressor Protein p53 / chemistry
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(42), 14722–14725.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; DNA / chemistry; DNA / metabolism; Deoxyribonucleases / metabolism; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Liberation; Humans; MCF-7 Cells; Models, Molecular; Molecular Conformation; Nanoparticles / chemistry
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Drug Delivery: Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy (Adv. Funct. Mater. 16/2014)
Advanced Functional Materials, 24(16), 2258–2258.
Source: Crossref
Added: April 3, 2022
2014 journal article
Drug Delivery: Ultrasound-Triggered Regulation of Blood Glucose Levels Using Injectable Nano-Network (Adv. Healthcare Mater. 6/2014)
Advanced Healthcare Materials, 3(6), 789–789.
Source: Crossref
Added: August 28, 2020
2014 review
Emerging micro-and nanotechnology based synthetic approaches for insulin delivery
[Review of ]. CHEMICAL SOCIETY REVIEWS, 43(10), 3595–3629.
MeSH headings : Diabetes Mellitus / drug therapy; Drug Delivery Systems; Equipment Design; Humans; Insulin / administration & dosage; Insulin / therapeutic use; Insulin Infusion Systems; Nanotechnology / instrumentation
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53(23), 5815–5820.
author keywords: ATP; drug delivery; liposomes; nanomedicine; stimuli-responsive materials
MeSH headings : Adenosine Triphosphate / metabolism; Animals; Drug Delivery Systems / methods; Humans; Liposomes / metabolism; MCF-7 Cells; Mice; Nanomedicine / methods
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Enzyme-responsive nanomaterials for controlled drug delivery
NANOSCALE, 6(21), 12273–12286.
MeSH headings : Animals; Apoptosis; Biotechnology; Drug Delivery Systems; Enzymes / chemistry; Humans; Inorganic Chemicals / chemistry; Liposomes / chemistry; Metal Nanoparticles / chemistry; Mice; Nanostructures / chemistry; Nanotechnology; Oxidoreductases / chemistry; Peptide Hydrolases / chemistry; Phospholipases / chemistry
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs
BIOMATERIALS, 35(25), 7194–7203.
author keywords: Graft copolymer; Micelle; Combination therapy; Bio-inspired; Ring open polymerization; Nanomedicine
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Camptothecin / chemistry; Camptothecin / pharmacology; Cell Line, Tumor; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Endocytosis / drug effects; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Nude; Micelles; Nanostructures / chemistry; Polyethylene Glycols / chemistry; Polymers / chemistry; Xenograft Model Antitumor Assays
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene
Advanced Materials, 27(6), 1021–1028.
MeSH headings : Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Cell Line, Tumor; Cytokines / administration & dosage; Cytokines / chemistry; Diffusion; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Furin / metabolism; Graphite / chemistry; Humans; Nanocapsules / administration & dosage; Nanocapsules / chemistry; Nanocapsules / ultrastructure; Neoplasms, Experimental / drug therapy; Neoplasms, Experimental / pathology; Oxides / chemistry; Particle Size; Peptides / pharmacokinetics; Polyethylene Glycols / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; TNF-Related Apoptosis-Inducing Ligand / chemistry; Treatment Outcome
Source: Crossref
Added: March 27, 2021
2014 journal article
Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo
Advanced Healthcare Materials, 3(9), 1392–1397.
MeSH headings : Animals; Gene Expression; Gene Silencing; HeLa Cells; Humans; Lipids / chemistry; Lipids / pharmacokinetics; Mice; Mice, Inbred C57BL; Nanostructures / chemistry; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; Transfection / methods; Triazines / chemistry
Source: Crossref
Added: April 3, 2022
2014 journal article
Molecule Drugs for Enhanced Therapeutic Efficacy
ADVANCED FUNCTIONAL MATERIALS, 24(16), 2295–2304.
author keywords: drug delivery; combination cancer therapy; site-specific delivery; nanomedicine; apoptosis
Source: Web Of Science
Added: August 6, 2018
2014 article
Recent progress in multidrug delivery to cancer cells by liposomes
Mo, R., Jiang, T., & Gu, Z. (2014, June). NANOMEDICINE, Vol. 9, pp. 1117–1120.
author keywords: chemotherapy; co-delivery; combination cancer therapy; drug delivery; gene therapy; liposome; protein therapy
MeSH headings : Antineoplastic Agents / administration & dosage; Drug Delivery Systems; Genetic Therapy; Humans; Liposomes / chemistry; Neoplasms / drug therapy; Neoplasms / therapy
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery
CHEMICAL COMMUNICATIONS, 50(95), 15105–15108.