2007 article

A binary matrix for background suppression in MALDI-MS of small molecules

Guo, Z., & He, L. (2007, March). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 387, pp. 1939–1944.

By: Z. Guo n & L. He n

author keywords: MALDI-MS; binary matrix; matrix background suppression; small molecule detection
TL;DR: An approach in which a mixture of two conventional MALDI matrices with different proton affinity was used to suppress the formation of matrix clusters and fragments yields cleaner MS spectra of fewer background peaks in both positive and negative-mode detection of small molecules. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Mass spectrometry imaging of small molecules using desorption/ionization on silicon

ANALYTICAL CHEMISTRY, 79(10), 3535–3541.

By: Q. Liu n, Z. Guo n & L. He n

MeSH headings : Animals; Cell Line; Cytological Techniques; Diagnostic Imaging / methods; Humans; Lasers; Liver / cytology; Liver / ultrastructure; Mass Spectrometry / methods; Mice; Phosphatidylcholines; Propidium; Silicon
TL;DR: The use of a matrix-free mass spectrometric imaging method, i.e., desorption/ionization on silicon (DIOS), for biological surface analysis, and a good correlation of the spatial distribution of cells confirmed the validity of this DIOS imaging approach. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 review

Nanomaterials in mass spectrometry ionization and prospects for biological application

[Review of ]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 384(3), 584–592.

By: Z. Guo n, A. Ganawi n, Q. Liu n & L. He n

author keywords: nanomaterials; mass spectrometry; bioanalysis
MeSH headings : Biology; Mass Spectrometry / methods; Nanostructures / analysis; Nanostructures / chemistry; Nanostructures / ultrastructure; Sensitivity and Specificity
TL;DR: A brief review summarizes recent developments in the field with the focus on the use of nanomaterials as alternative media to facilitate analyte ionization in laser-desorption ionization–mass spectrometry (LDI–MS) and secondary ion mass spectrometer (SIMS). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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