Zach Hetzler

College of Engineering

Works (7)

Updated: June 29th, 2024 05:00

2024 article

Adeno-associated virus genome quantification with amplification-free CRISPR-Cas12a

Hetzler, Z., Marinakos, S. M., Lott, N., Mohammad, N., Lass-Napiorkowska, A., Kolbe, J., … Wei, Q. (2024, March 25). GENE THERAPY, Vol. 3.

By: Z. Hetzler n, S. Marinakos, N. Lott n, N. Mohammad n , A. Lass-Napiorkowska *, J. Kolbe n, L. Turrentine n, D. Fields n ...

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Sources: Web Of Science, NC State University Libraries
Added: April 15, 2024

2024 article

Liquid Metal-Based Biosensors: Fundamentals and Applications

Jamalzadegan, S., Kim, S., Mohammad, N., Koduri, H., Hetzler, Z., Lee, G., … Wei, Q. (2024, January 23). ADVANCED FUNCTIONAL MATERIALS, Vol. 1.

By: S. Jamalzadegan n, S. Kim n , N. Mohammad n , H. Koduri n, Z. Hetzler n, G. Lee n, M. Dickey n , Q. Wei n 

author keywords: biosensors; liquid metals; wearable sensors; soft materials; precision health; point-of-care
TL;DR: The recent progress of LM‐based biosensors for personalized healthcare and disease monitoring via both physical and biochemical signaling is survey and the challenges and future directions of LM‐integrated biosensor platforms is discussed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 12, 2024

2024 journal article

Ratiometric nonfluorescent CRISPR assay utilizing Cas12a-induced plasmid supercoil relaxation

COMMUNICATIONS CHEMISTRY, 7(1).

By: N. Mohammad n , L. Talton n, S. Dalgan n, Z. Hetzler n, A. Steksova n & Q. Wei n 

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Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 24, 2024

2023 journal article

Low-rate smartphone videoscopy for microsecond luminescence lifetime imaging with machine learning

PNAS NEXUS, 2(10).

By: Y. Wang  n, S. Sadeghi n, A. Velayati n, R. Paul  n, Z. Hetzler n, E. Danilov n , F. Ligler*, Q. Wei n 

Ed(s): R. Reis

author keywords: smartphone videoscopy; V-chopper; time-resolved; lifetime imaging; machine learning
TL;DR: A cost-effective and miniaturized smartphone lifetime imaging system integrated with a pulsed ultraviolet (UV) light-emitting diode (LED) for 2D luminescence lifetime imaging using a videoscopy-based virtual chopper (V-chopper) mechanism combined with machine learning. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 6, 2023

2023 journal article

Single-use biosensors for biomanufacturing: Perspective on the state-of-the-art

CURRENT OPINION IN BIOMEDICAL ENGINEERING, 28.

By: Z. Hetzler n, N. Lott n, A. Poonam n, S. Dalgan n & Q. Wei n 

author keywords: Biomanufacturing; Gene therapy; Process monitoring; Process analytical technology (PAT); Single-use sensors
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 2, 2024

2023 article

Unidirectional trans-cleaving behavior of CRISPR-Cas12a unlocks for an ultrasensitive assay using hybrid DNA reporters containing a 3' toehold

Mohammad, N., Talton, L., Hetzler, Z., Gongireddy, M., & Wei, Q. (2023, August 31). NUCLEIC ACIDS RESEARCH, Vol. 8.

By: N. Mohammad n , L. Talton n, Z. Hetzler n, M. Gongireddy n & Q. Wei n 

TL;DR: This study not only unfolded new insight into the trans-cleavage behavior of Cas12a but also demonstrated a sensitive CRISPR-Cas12a assay by using a hybrid dsDNA reporter molecule. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 18, 2023

2022 journal article

Flexible sensor patch for continuous carbon dioxide monitoring

FRONTIERS IN CHEMISTRY, 10.

By: Z. Hetzler n, Y. Wang n, D. Krafft n, S. Jamalzadegan n, L. Overton n, M. Kudenov n, F. Ligler*, Q. Wei n 

author keywords: CO2; in-line sensor; flexible sensor; process analytical technology; cell culture; biomanufacturing
Sources: Web Of Science, NC State University Libraries
Added: March 6, 2023

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