Zhuo Tan

Works (5)

Updated: August 23rd, 2023 21:15

2017 article

Antibacterial efficacy and cytotoxicity of low intensity direct current activated silver–titanium implant system prototype

Tan, Z., Havell, E. A., Orndorff, P. E., & Shirwaiker, R. A. (2017, January 16). BioMetals, Vol. 30, pp. 113–125.

By: Z. Tan n, E. Havell n, P. Orndorff n & R. Shirwaiker n 

Contributors: Z. Tan n, E. Havell n, P. Orndorff n & R. Shirwaiker n 

author keywords: Low intensity direct current; Silver-titanium implant; Orthopaedic application; Antimicrobial efficacy; Cytotoxicity
MeSH headings : Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Cell Proliferation / drug effects; Ions / chemistry; Methicillin-Resistant Staphylococcus aureus / drug effects; Methicillin-Resistant Staphylococcus aureus / pathogenicity; Silver / chemistry; Silver / pharmacology; Staphylococcal Infections / drug therapy; Staphylococcal Infections / microbiology; Titanium / chemistry; Titanium / pharmacology
topics (OpenAlex): Nanoparticles: synthesis and applications; Bone Tissue Engineering Materials; Graphene and Nanomaterials Applications
TL;DR: The in vitro antibacterial efficacy and cytotoxicity of a low intensity direct current (LIDC)-activated silver–titanium implant system prototype designed for localized generation and delivery of silver ions at the implantation site showed high antimicrobial efficacy against MRSA, but was also toxic to human cells immediately surrounding the electrodes. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 article

Effects of Electrically Activated Silver–Titanium Implant System Design Parameters on Time-Kill Curves Against Staphylococcus aureus

Tan, Z., Xu, G., Orndorff, P. E., & Shirwaiker, R. A. (2016, June 1). Journal of Medical and Biological Engineering, Vol. 36, pp. 325–333.

By: Z. Tan n, G. Xu n, P. Orndorff n & R. Shirwaiker n 

Contributors: Z. Tan n, G. Xu n, P. Orndorff n & R. Shirwaiker n 

author keywords: Antimicrobial efficacy; Orthopaedic implants; Ionic silver; Post-operative infections; Design parameters
topics (OpenAlex): Nanoparticles: synthesis and applications; Bone Tissue Engineering Materials; Neuroscience and Neural Engineering
TL;DR: The in vitro antimicrobial efficacy of a silver-based prophylactic system for orthopaedic implant applications is characterized and provides a reference of design parameters for future product engineering. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 article

Evaluation of silver‐titanium implants activated by low intensity direct current for orthopedic infection control: An in vitro and in vivo study

Cavanaugh, D. L., Tan, Z., Norris, J. P., Hardee, A., Weinhold, P. S., Dahners, L. E., … Shirwaiker, R. A. (2015, May 21). Journal of Biomedical Materials Research Part B Applied Biomaterials, Vol. 104, pp. 1023–1031.

By: D. Cavanaugh *, Z. Tan n, J. Norris *, A. Hardee n, P. Weinhold n, L. Dahners*, P. Orndorff n, R. Shirwaiker n 

Contributors: D. Cavanaugh *, Z. Tan n, J. Norris *, A. Hardee n, P. Weinhold n, L. Dahners*, P. Orndorff n, R. Shirwaiker n 

author keywords: prosthetic infection; oligodynamic silver; antimicrobial implant; electrical activation
MeSH headings : Animals; Female; Femur / microbiology; Femur / surgery; Implants, Experimental; Rats; Rats, Sprague-Dawley; Silver / chemistry; Silver / pharmacology; Staphylococcal Infections / prevention & control; Staphylococcus aureus / growth & development; Titanium / chemistry; Titanium / pharmacology
topics (OpenAlex): Bone Tissue Engineering Materials; Orthopaedic implants and arthroplasty; Nanoparticles: synthesis and applications
TL;DR: In vivo, none of the four groups were able to prevent wound infection, but the experimental group resulted in reduced colonization, and the antimicrobial potential of LIDC-activated Ag-Ti implants is demonstrated. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 article

Determining Optimal Current Intensity and Duration for Electrically Activated Silver-Based Prophylactic Hip Implant Prototype Design

Tan, Z., Shirwaiker, R. A., & Orndoff, P. E. (2013, June 26). Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions.

By: Z. Tan n, R. Shirwaiker n  & P. Orndoff n

Contributors: Z. Tan n, R. Shirwaiker n  & P. Orndoff n

topics (OpenAlex): Orthopedic Infections and Treatments; Orthopaedic implants and arthroplasty; Bacterial biofilms and quorum sensing
TL;DR: Preliminary in vitro and in vivo results have demonstrated the potency of silver-based OI as an effective local antibacterial therapy in osteomyelitis treatment with advantages over various antibiotics. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2012 article

Biocompatibility analysis of an electrically-activated silver-based antibacterial surface system for medical device applications

Samberg, M. E., Tan, Z., Monteiro-Riviere, N. A., Orndorff, P. E., & Shirwaiker, R. A. (2012, December 15). Journal of Materials Science Materials in Medicine, Vol. 24, pp. 755–760.

By: M. Samberg n, Z. Tan*, N. Monteiro-Riviere n , P. Orndorff n & R. Shirwaiker n 

Contributors: M. Samberg n, Z. Tan*, N. Monteiro-Riviere n , P. Orndorff n & R. Shirwaiker n 

MeSH headings : Anti-Bacterial Agents; Biocompatible Materials; Equipment and Supplies; Escherichia coli / drug effects; Microbial Sensitivity Tests; Silver; Staphylococcus aureus / drug effects; Surface Properties
topics (OpenAlex): Bone Tissue Engineering Materials; Graphene and Nanomaterials Applications; Nanoparticles: synthesis and applications
TL;DR: The study concluded that the technological applications of the surface system for medical devices and surgical tools, which contact human tissues for less than 1.5 h, are expected to be self-sterilizing without causing toxicity in vivo. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

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