2018 journal article

Direct nanodrug delivery for tumor targeting subject to shear-augmented diffusion in blood flow

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 56(11), 1949–1958.

By: Z. Xu n & C. Kleinstreuer n

author keywords: Nanodrug delivery; Red blood cell interaction; Liver tumor targeting; Shear-induced diffusion; Computer simulations
MeSH headings : Computer Simulation; Diffusion; Drug Delivery Systems / methods; Humans; Hydrodynamics; Nanoparticles / administration & dosage; Neoplasms / drug therapy; Particle Size; Pharmaceutical Preparations / administration & dosage; Regional Blood Flow / physiology
TL;DR: Results from computer simulations under physiologically realistic conditions indicate that shear-induced diffusion has a significant effect on nanoparticle transport, even in large arteries, and direct nanodrug delivery to tumor-feeding hepatic artery branches is feasible. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 5, 2018

2016 journal article

Solid Tumor Embolotherapy in Hepatic Arteries with an Anti-reflux Catheter System

ANNALS OF BIOMEDICAL ENGINEERING, 44(4), 1036–1046.

By: Z. Xu n, S. Jernigan n, C. Kleinstreuer n & G. Buckner n

author keywords: Liver cancer; Transient particle-hemodynamics; Embolization; Particle-reflux; Infusion-stop point; Excessive particle capture
MeSH headings : Blood Pressure; Carcinoma, Hepatocellular / therapy; Catheters; Embolization, Therapeutic; Hemodynamics; Hepatic Artery / physiology; Humans; Liver Neoplasms / therapy; Microspheres; Models, Biological
TL;DR: The results show that the present procedure for embolization of downstream vessels which feed a tumor is quite arbitrary, Nevertheless, a method to recycle aberrant particles captured by the deployed tip was proposed to minimize side-effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Fabrication of three-dimensional hierarchical nanostructures using template-directed colloidal assembly

NANOSCALE, 7(10), 4406–4410.

By: J. Elek n, X. Zhang n, B. Dai n, Z. Xu n & C. Chang n

TL;DR: Optical effects in template-directed colloidal assembly are explored to fabricate microscale patterns with integrated three-dimensional (3D) nanostructures to enable low-cost fabrication of hierarchical devices. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Concentration photovoltaic-thermal energy co-generation system using nanofluids for cooling and heating

ENERGY CONVERSION AND MANAGEMENT, 87, 504–512.

By: Z. Xu n & C. Kleinstreuer n

author keywords: Co-generation; Concentration photovoltaic-thermal (CPV/T) system; Nanofluid thermal conductivity; System efficiencies
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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