Works Published in 2013
Displaying all 12 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 magazine article
Biopharmaceutical Microbial Contamination Control
Pharmaceutical Processing.
Contributors: L. Clontz, G. Gilleskie & N. Hentz
Source: ORCID
Added: October 16, 2022
2013 journal article
Bioactive Cellulose Nanofibrils for Specific Human IgG Binding
BIOMACROMOLECULES, 14(12), 4161–4168.
MeSH headings : Adsorption; Biosensing Techniques; Cellulose / chemistry; Cellulose / ultrastructure; Chromatography, Affinity; Humans; Immobilized Proteins; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Kinetics; Microscopy, Atomic Force; Nanofibers / chemistry; Nanofibers / ultrastructure; Peptide Fragments / chemistry; Polymerization; Polymethacrylic Acids / chemistry; Protein Binding; Quartz Crystal Microbalance Techniques; Signal-To-Noise Ratio; Surface Properties
TL;DR:
The effects of initiator concentration and thickness of poly(AMA-co-HEMA) layer on hIgG adsorption were investigated in the developed systems, which exhibited high signal-to-noise response.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Reversible cyclic peptide libraries for the discovery of affinity ligands
Analytical Chemistry, 85(19), 9229–9237.
MeSH headings : Ligands; Molecular Structure; Peptide Library; Peptides, Cyclic / analysis; Tandem Mass Spectrometry
TL;DR:
A method is shown for synthesis of the irreversible cyclic peptide corresponding to the proposed depsipeptide structure, to make the ligand stable to the aqueous acid and alkaline conditions encountered in affinity chromatographic applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Specificity and Regenerability of Short Peptide Ligands Supported on Polymer Layers for Immunoglobulin G Binding and Detection
ACS APPLIED MATERIALS & INTERFACES, 5(16), 8030–8037.
author keywords: short peptide ligands; immunoglobulin G detection; surface plasmon resonance; quartz crystal microgravimetry; regenerability; storage stability
MeSH headings : Electrophoresis, Polyacrylamide Gel; Humans; Immunoglobulin G / chemistry; Immunoglobulin G / isolation & purification; Ligands; Methacrylates / chemistry; Peptides / chemistry; Polyhydroxyethyl Methacrylate / chemistry; Polymers / chemistry; Protein Binding; Surface Plasmon Resonance
TL;DR:
Results from sodium dodecyl sulfate polyacrylamide gel electrophoresis and fluorescence microscopy indicate that the bioactive system is highly specific to IgG and resistant to nonspecific interactions when tested in mixed protein solutions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Peptide-based affinity adsorbents with high binding capacity for the purification of monoclonal antibodies
Industrial & Engineering Chemistry Research, 52(26), 8800–8811.
TL;DR:
The development of affinity resins based on hexapeptide ligand HWRGWV for recovering monoclonal antibodies from cell culture fluids and the reaction conditions of peptide coupling were optimized to maximize the binding capacity of the resulting adsorbents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Conservation and Distribution of the Benzalkonium Chloride Resistance Cassette bcrABC in Listeria monocytogenes
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(19), 6067–6074.
MeSH headings : Benzalkonium Compounds / pharmacology; Chromosomes, Bacterial; Conserved Sequence; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Disinfectants / pharmacology; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Listeria monocytogenes / drug effects; Listeria monocytogenes / genetics; Molecular Sequence Data; Multigene Family; Plasmids; Sequence Analysis, DNA; Transcription, Genetic
TL;DR:
Analysis of a panel of 116 Listeria monocytogenes strains of diverse serotypes and sources revealed that all but one of the 71 benzalkonium chloride-resistant (BCr) isolates harbored bcrABC, previously identified on a large plasmid of the 1998-1999 hot dog outbreak strain H7858.
(via Semantic Scholar)
aem.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Affinity chromatographic purification of human immunoglobulin a from chinese hamster ovary cell culture supernatant
BIOTECHNOLOGY PROGRESS, 29(1), 91–98.
author keywords: affinity chromatography; hexamer peptide; CHO; human immunoglobulin; secretory IgA
MeSH headings : Adsorption; Animals; CHO Cells; Cells, Cultured; Chromatography, Affinity; Cricetinae; Cricetulus; Humans; Immunoglobulin A / isolation & purification; Oligopeptides / chemical synthesis; Oligopeptides / chemistry; Surface Properties
TL;DR:
The peptide ligand resins exhibit great potential for large‐scale purification of both human IgA and secretory IgA, respectively, and the DBC value of HWRGWV for IgA is much greater than current commercially available affinity ligands.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Specific Binding of Immunoglobulin G with Bioactive Short Peptides Supported on Antifouling Copolymer Layers for Detection in Quartz Crystal Microgravimetry and Surface Plasmon Resonance
ANALYTICAL CHEMISTRY, 85(2), 1106–1113.
MeSH headings : Binding Sites; Biofouling / prevention & control; Humans; Immunoglobulin G / chemistry; Particle Size; Peptides / chemical synthesis; Peptides / chemistry; Polymers / chemistry; Quartz Crystal Microbalance Techniques; Surface Plasmon Resonance; Surface Properties
TL;DR:
The effect of copolymer molecular composition and analyte concentration was elucidated in order to design systems based on immobilized peptides for high signal-to-noise response and detection limits that meet the requirements for IgG biosensing in fluid matrixes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Affinity chromatographic purification of human immunoglobulin M from human B lymphocyte cell culture supernatant
BIOCHEMICAL ENGINEERING JOURNAL, 70, 63–70.
author keywords: Affinity chromatography; Hexamer peptide; Human immunoglobulin; IgM; Dynamic binding capacity; Elution additive
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
A new strategy for ultralow biofouling membranes: Uniform and ultrathin hydrophilic coatings using liquid carbon dioxide
JOURNAL OF MEMBRANE SCIENCE, 440, 88–97.
author keywords: Hydrophilization; Liquid carbon dioxide; Coating; Biofouling
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands
Biotechnology and Bioengineering, 110(3), 857–870.
author keywords: cyclic peptide; mRNA display; Fc binding; affinity ligand; library
MeSH headings : Humans; Immunoglobulin Fc Fragments / metabolism; Peptide Library; Peptides, Cyclic / chemistry; Peptides, Cyclic / genetics; Peptides, Cyclic / isolation & purification; Peptides, Cyclic / metabolism; Protein Binding; Protein Engineering / methods; RNA, Messenger / genetics; Solid-Phase Synthesis Techniques / methods
TL;DR:
The discovery, synthesis and characterization of novel cyclic peptide affinity ligands that bind the Fc portion of human Immunoglobulin G (IgG; hFc) are described and the approach can be extended to efficiently generate and evaluatecyclic peptides for other targets of interest.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2013 journal article
Affinity membrane development from PBT nonwoven by photo-induced graft polymerization, hydrophilization and ligand attachment
JOURNAL OF MEMBRANE SCIENCE, 428, 562–575.
author keywords: Affinity membrane; Functional nonwoven fabrics; Surface modification; Protein purification; Nonspecific protein adsorption
TL;DR:
The DEG modified membrane was further developed by attachment of a specific proprietary ligand that binds to the prion protein, the agent responsible for transmissible spongiform encephalopathies, and showed good selectivity for the capture of prionprotein from hamster brain homogenate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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