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Works Published in 2020

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Displaying all 9 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 article

Synthetic biology, combinatorial biosynthesis, and chemo-enzymatic synthesis of isoprenoids (September, 10.1007/s10295-020-02306-3, 2020)

Malico, A. A., Calzini, M. A., Gayen, A. K., & Williams, G. J. (2020, December). JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, Vol. 47, pp. 1181–1181.

By: A. Malico n, M. Calzini n, A. Gayen n & G. Williams n

TL;DR: The article title was published incorrectly in the HTML version (online version only) of the online published article. (via Semantic Scholar)
Source: Web Of Science
Added: November 30, 2020

2020 journal article

Recycled eggshells as precursors for iron-impregnated calcium oxide catalysts for partial oxidation of methane

BIORESOURCES AND BIOPROCESSING, 7(1).

By: G. Karoshi n, P. Kolar n, S. Shah n & G. Gilleskie n

author keywords: Eggshell; Iron; Methane; Catalyst; Partial oxidation
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: September 7, 2020

2020 journal article

Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities

JOURNAL OF CHROMATOGRAPHY A, 1625.

By: H. Reese n, X. Xiao n, C. Shanahan n, G. Driessche n, D. Fourches n, R. Carbonell n, C. Hall n, S. Menegatti n

author keywords: Peptide affinity ligands; Protein A; mAb purification; Affinity chromatography; Peptide design
MeSH headings : Amino Acid Sequence; Animals; Antibodies, Monoclonal / isolation & purification; Antibodies, Monoclonal / metabolism; CHO Cells; Chromatography, Affinity / methods; Cricetinae; Cricetulus; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Ligands; Peptides / chemical synthesis; Peptides / chemistry; Peptides / metabolism; Protein Binding; Staphylococcal Protein A / chemistry; Staphylococcal Protein A / metabolism
TL;DR: WQRHGI-WorkBeads resin was finally characterized by purification of a monoclonal antibody from a Chinese Hamster Ovary cell culture harvest, affording a remarkable HCP LRV of 2.7, and consistent product yield and purity over 100 chromatographic cycles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 10, 2020

2020 journal article

A falling film bioreactor (FFBR) for generating effective gas-to-liquid mass transfer using wavy laminar flow for continuous microbial gas processing

CHEMICAL ENGINEERING SCIENCE, 219.

By: R. Barton n, K. VanTreeck n, C. Duran n, M. Schulte n & M. Flickinger n

author keywords: Falling film bioreactor; Biocomposite biocatalyst; Cell immobilization; Process intensification; Gas-liquid mass transfer; Gas-to-liquid chemicals
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: May 26, 2020

2020 journal article

Preservatives accelerate the horizontal transfer of plasmid-mediated antimicrobial resistance genes via differential mechanisms

ENVIRONMENT INTERNATIONAL, 138.

By: T. Cen*, X. Zhang n, S. Xie* & D. Li*

author keywords: Antimicrobial resistance genes (ARGs); Preservatives; Conjugative transfer; RpoS regulon; SOS response
MeSH headings : Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial / genetics; Gene Transfer, Horizontal; Genes, Bacterial; Plasmids
TL;DR: The results demonstrated that these preservatives (sodium nitrite, sodium benzoate, and triclocarbon), under daily-use concentrations, led to concentration-dependent increases in conjugative transfer, subsequently promoting horizontal transfer of antimicrobial resistance genes (ARGs). (via Semantic Scholar)
Source: Web Of Science
Added: April 20, 2020

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh n, D. Paudel n, H. Brochu n, K. Popowski n, M. Gracieux n, J. Cores n, K. Huang n, M. Hensley n ...

MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
TL;DR: It is shown that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells. (via Semantic Scholar)
Source: Web Of Science
Added: March 23, 2020

2020 journal article

A direct comparison between membrane adsorber and packed column chromatography performance

JOURNAL OF CHROMATOGRAPHY A, 1612.

By: C. Boi, A. Malavasi n, R. Carbonell n & G. Gilleskie n

author keywords: Chromatography; Membrane adsorber; Packed column; Binding capacity; Productivity
MeSH headings : Adsorption; Anion Exchange Resins; Chromatography, Ion Exchange / methods; Proteins / isolation & purification; Serum Albumin, Bovine / isolation & purification
TL;DR: The comparison was performed using anion exchange media with the same ligand immobilized on the adsorbing surface, namely the strong Q quaternary ammonium group, R-CH2-N+-(CH3)3, and bovine serum albumin as a model protein to confirm the better performance of membrane chromatography at high flow rates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: March 10, 2020

2020 journal article

Valorization of Eggshell Waste into Supported Copper Catalysts for Partial Oxidation of Methane

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH, 14(1), 61–70.

By: G. Karoshi n, P. Kolar n, S. Shah n & G. Gilleskie n

author keywords: Eggshell; Copper; Catalyst; Methane; Partial oxidation
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: December 9, 2019

2020 journal article

Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis

BIOTECHNOLOGY AND BIOENGINEERING, 117(2), 438–452.

By: R. Lavoie n, A. Fazio n, T. Williams n, R. Carbonell n & S. Menegatti n

author keywords: host cell proteins; monoclonal antibodies; polishing; peptide ligands; protein purification
MeSH headings : Animals; Antibodies, Monoclonal / isolation & purification; CHO Cells; Cricetinae; Cricetulus; Ligands; Peptides / chemistry; Peptides / metabolism; Protein Binding; Proteins / analysis; Proteins / chemistry; Proteins / isolation & purification; Proteins / metabolism; Proteomics / methods; Recombinant Proteins / isolation & purification
TL;DR: A family of synthetic peptides that target HCPs and exhibit low binding to IgG product are developed and found that these peptide ligands exhibit superior HCP binding capability compared to those of the benchmark commercial resins commonly used in mAb purification. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 2, 2019

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