Works Published in 2014

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Displaying works 21 - 40 of 101 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 conference paper

Sparse multivariate function recovery with a high error rate in the evaluations

Proceedings of the 39th International Symposium on Symbolic and Algebraic Computation - ISSAC '14. Presented at the the 39th International Symposium.

Event: the 39th International Symposium

TL;DR: A different algorithm is presented that can interpolate a sparse multivariate rational function from evaluations where the error rate is 1/q for any q > 2, which the ISSAC 2013 algorithm could not handle. (via Semantic Scholar)
Source: Crossref
Added: July 21, 2019

2014 journal article

Comparison of serological and molecular panels for diagnosis of vector-borne diseases in dogs

Parasites & Vectors, 7(1), 127.

By: R. Maggi n, A. Birkenheuer n, B. Hegarty n, J. Bradley n, M. Levy n & E. Breitschwerdt n

author keywords: Canine vector-borne diseases; Serology; Molecular testing; Diagnostic panel
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / diagnosis; Bacterial Infections / microbiology; Bacterial Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / parasitology; Serologic Tests / veterinary
TL;DR: Serological and PCR assays should be used in parallel to maximize CVBD diagnosis, and a panel combining serological and molecular assays run in parallel resulted in a 4-58% increase in the recognition of exposure to or infection with CVBD. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019

2014 conference paper

Determining optimal current intensity and duration for electrically activated silver-based prophylactic hip implant prototype design

Proceedings of the ASME Summer Bioengineering Conference - 2013, pt B.

By: Z. Tan n, R. Shirwaiker n & P. Orndoff n

TL;DR: Preliminary in vitro and in vivo results have demonstrated the potency of silver-based OI as an effective local antibacterial therapy in osteomyelitis treatment with advantages over various antibiotics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 7.

By: A. Tommasi*, D. Otranto*, T. Furlanello*, S. Tasca*, C. Cantacessi*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres* ...

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2014 journal article

Modeling genetic effects on growth of diverse provenances and families of loblolly pine across optimum and deficient nutrient regimes

CANADIAN JOURNAL OF FOREST RESEARCH, 44(11), 1453–1461.

By: B. Smith n, B. Bullock n, F. Isik n & S. McKeand n

author keywords: loblolly pine; Chapman-Richards function; genotype x environment interaction; growth and yield; fertilization
TL;DR: This study tests if the relative growth performance of provenances and families is the same at the individual-tree and stand levels for family block plantings and determines what type of adjustment may be required to account for genetic differences when modeling growth and yield. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

C/EBP alpha regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G(1)/S checkpoint

CELL CYCLE, 13(22), 3602–3610.

author keywords: C/EBP alpha; CRL4(Cdt2); G(1)/S DNA damage checkpoint; keratinocytes; p21
MeSH headings : Animals; CCAAT-Enhancer-Binding Protein-alpha / genetics; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cyclin-Dependent Kinase Inhibitor p21 / metabolism; DNA Damage / genetics; DNA Damage / radiation effects; G1 Phase Cell Cycle Checkpoints / genetics; Keratinocytes / metabolism; Keratinocytes / radiation effects; Mice; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Proteolysis; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism; Ultraviolet Rays; p21-Activated Kinases / genetics; p21-Activated Kinases / metabolism
TL;DR: Findings reveal C/EBPα regulates G1/S cell cycle arrest in response to DNA damage via the control of CRL4Cdt2 mediated degradation of p21. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Modifying Caspase-3 Activity by Altering Allosteric Networks

BIOCHEMISTRY, 53(48), 7582–7595.

MeSH headings : Allosteric Site / genetics; Amino Acid Substitution; Caspase 3 / chemistry; Caspase 3 / genetics; Caspase 3 / metabolism; Crystallography, X-Ray; Humans; Kinetics; Models, Molecular; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Conformation; Protein Multimerization; Protein Structure, Quaternary; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism
TL;DR: The data show that the caspase-3 native ensemble includes the canonical active state as well as an inactive conformation characterized by an intact substrate-binding pocket, but with an altered helix 3, which reflects the relative population of each species in the native ensemble. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Definition of the Cattle Killer Cell Ig-like Receptor Gene Family: Comparison with Aurochs and Human Counterparts

JOURNAL OF IMMUNOLOGY, 193(12), 6016–6030.

By: N. Sanderson*, P. Norman*, L. Guethlein*, S. Ellis*, C. Williams n, M. Breen n, S. Park*, D. Magee* ...

MeSH headings : Animals; Cattle; Chromosome Mapping; Chromosomes, Mammalian; Cloning, Molecular; Evolution, Molecular; Gene Library; Genetic Loci; Genome; Haplotypes; Humans; Immunoglobulins / genetics; Molecular Sequence Data; Multigene Family; Phenotype; Phylogeny; Receptors, IgG / metabolism; Receptors, KIR / classification; Receptors, KIR / genetics; Receptors, KIR / metabolism; Receptors, Natural Killer Cell / metabolism; Sequence Analysis, DNA; Signal Transduction; Telomere
Source: Web Of Science
Added: August 6, 2018

2014 journal article

An Ephemeral Sexual Population of Phytophthora infestans in the Northeastern United States and Canada

PLOS ONE, 9(12).

By: G. Danies*, K. Myers*, M. Mideros*, S. Restrepo*, F. Martin*, D. Cooke*, C. Smart*, J. Ristaino n ...

MeSH headings : Canada; DNA, Mitochondrial / chemistry; Genetic Markers; Genotype; Haplotypes; Microsatellite Repeats; Phytophthora infestans / genetics; Phytophthora infestans / physiology; Population Density; Reproduction; United States
TL;DR: It is concluded that US-22 could be a parent of some, but not all, of the new genotypes found in 2010 and 2011 that were detected in a region that centered around central New York State. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Zoonotic Bartonella Species in Cardiac Valves of Healthy Coyotes, California, USA

Emerging Infectious Diseases, 20(12), 2133–2136.

MeSH headings : Animal Diseases / epidemiology; Animal Diseases / microbiology; Animals; Bartonella / classification; Bartonella / genetics; Bartonella Infections / veterinary; California / epidemiology; Coyotes / microbiology; DNA, Bacterial; Endocarditis, Bacterial / veterinary; Female; Genotype; Geography, Medical; Heart Valve Diseases / veterinary; Male; Zoonoses / epidemiology; Zoonoses / microbiology
TL;DR: Bartonella infection apparently leads to cardiac valve tropism, which could cause endocarditis, an often lethal complication in mammals, including humans. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Stable synthetic mono-substituted cationic bacteriochlorins mediate selective broad-spectrum photoinactivation of drug-resistant pathogens at nanomolar concentrations

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 141, 119–127.

MeSH headings : Apoptosis / drug effects; Apoptosis / radiation effects; Candida albicans / drug effects; Candida albicans / radiation effects; Cations / chemistry; Cryptococcus neoformans / drug effects; Cryptococcus neoformans / radiation effects; Drug Resistance, Bacterial / drug effects; Drug Resistance, Bacterial / radiation effects; Drug Resistance, Fungal / drug effects; Drug Resistance, Fungal / radiation effects; Fluorescent Dyes / chemistry; Gram-Negative Bacteria / drug effects; Gram-Negative Bacteria / radiation effects; Gram-Positive Bacteria / drug effects; Gram-Positive Bacteria / radiation effects; HeLa Cells; Humans; Light; Photosensitizing Agents / chemical synthesis; Photosensitizing Agents / chemistry; Photosensitizing Agents / pharmacology; Porphyrins / chemical synthesis; Porphyrins / chemistry; Porphyrins / pharmacology; Singlet Oxygen / chemistry; Singlet Oxygen / pharmacology
TL;DR: The highly active photodynamic inactivation of microbial cells may stem from the amphiphilic and cationic features of the bacteriochlorins, which were tested against a panel of pathogenic microorganisms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Performance of a commercially available in-clinic ELISA for detection of antibodies against Anaplasma phagocytophilum, Anaplasma platys, Borrelia burgdorferi, Ehrlichia canis, and Ehrlichia ewingii and Dirofilaria immiti santigen in dogs

Journal of the American Veterinary Medical Association, 245(1), 80–86.

By: B. Stillman n, M. Monn n, J. Liu n, B. Thatcher n, P. Foster n, B. Andrews n, S. Little n, M. Eberts n ...

MeSH headings : Anaplasma / immunology; Anaplasmosis / blood; Anaplasmosis / diagnosis; Animals; Antibodies, Bacterial / blood; Antibodies, Helminth / blood; Borrelia burgdorferi / immunology; Dirofilaria immitis / immunology; Dirofilariasis / blood; Dirofilariasis / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Lyme Disease / blood; Lyme Disease / diagnosis; Lyme Disease / veterinary; Sensitivity and Specificity
TL;DR: Results of field evaluations confirmed that the in-clinic ELISA could be reliably used under typical clinical conditions to identify dogs exposed to the pathogens of interest. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Case Report: Molecular Evidence of Anaplasma platys Infection in Two Women from Venezuela

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 91(6), 1161–1165.

By: C. Arraga-Alvarado, B. Qurollo*, O. Parra, M. Berrueta, B. Hegarty* & E. Breitschwerdt*

MeSH headings : Adult; Anaplasma / genetics; Anaplasmosis / diagnosis; Base Sequence; DNA Primers; DNA, Bacterial / genetics; Female; Humans; Middle Aged; Polymerase Chain Reaction; Venezuela
TL;DR: Two case reports of Anaplasma platys detection in two women from Venezuela are presented, providing further support for A. platys as a zoonotic tick-borne pathogen, most likely of low pathogenicity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Bilateral mandibular pyogranulomatous lymphadenitis and pulmonary nodules in a dog with Bartonella henselae bacteremia

Canadian Veterinary Journal, 55(10), 970–974.

By: M. Tucker, R. Sellon, R. Tucker, T. Wills, A. Simonsen, R. Maggi, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Transcriptional and epigenetic responses to mating and aging in Drosophila melanogaster

BMC GENOMICS, 15.

By: S. Zhou n, T. Mackay n & R. Anholt n

author keywords: microRNA; Histone modification; ChipSeq; Environmental plasticity; Systems genetics
MeSH headings : Aging / genetics; Animals; Behavior, Animal; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Regulatory Networks; Histones / metabolism; Male; MicroRNAs / genetics; Oviposition / genetics; Phenotype; Reproduction / genetics; Transcription, Genetic / physiology
TL;DR: The results implicate microRNAs as mediators of phenotypic plasticity associated with mating and provide a comprehensive documentation of the genomic and epigenomic changes that accompany mating- and aging-induced physiological changes in female D. melanogaster. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Regional Seroreactivity and Vector-Borne Disease Co-Exposures in Dogs in the United States from 2004–2010: Utility of Canine Surveillance

Vector-Borne and Zoonotic Diseases, 14(10), 724–732.

author keywords: Dirofilaria; Rickettsia; Babesia; Ehrlichia; United States; Anaplasma; Borrelia; Bartonella; Surveillance
MeSH headings : Anaplasma / immunology; Anaplasmosis / epidemiology; Animals; Arachnid Vectors / microbiology; Arachnid Vectors / parasitology; Babesia / immunology; Babesiosis / epidemiology; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Borrelia burgdorferi / immunology; Coinfection / veterinary; Dirofilaria immitis / immunology; Dirofilariasis / epidemiology; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Ehrlichia / immunology; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Lyme Disease / epidemiology; Retrospective Studies; Rickettsia / immunology; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary; Ticks / microbiology; Ticks / parasitology; United States / epidemiology
TL;DR: Notable annual and regional seroreactivity variation was observed with certain pathogens over 7 years of study, suggesting canine surveillance studies may have value in contributing to future VBD knowledge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Panchromatic absorbers for solar light-harvesting

CHEMICAL COMMUNICATIONS, 50(93), 14512–14515.

TL;DR: A set of panchromatic absorbers exhibiting long excited-state lifetimes in both polar and nonpolar media has been prepared and should find utility in molecular solar-conversion systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Loading and Release Mechanism of Red Clover Necrotic Mosaic Virus Derived Plant Viral Nanoparticles for Drug Delivery of Doxorubicin

SMALL, 10(24), 5126–5136.

By: J. Cao n, R. Guenther n, T. Sit n, C. Opperman n, S. Lommel n & J. Willoughby n

MeSH headings : Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / pharmacokinetics; Capsid; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Carriers; Hydrogen-Ion Concentration; Nanoparticles; Tombusviridae / chemistry
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Intraoperative Bleeding in Dogs from Grenada Seroreactive to Anaplasma platys and Ehrlichia canis

Journal of Veterinary Internal Medicine, 28(6), 1702–1707.

By: M. Lanza-Perea*, U. Zieger*, B. Qurollo n, B. Hegarty n, E. Pultorak n, S. Kumthekar*, R. Bruhl-Day*, E. Breitschwerdt n

author keywords: Hemostasis; Infection; Rickettsia; Ticks
MeSH headings : Anaplasma; Anaplasmosis / blood; Anaplasmosis / complications; Anaplasmosis / epidemiology; Animals; Blood Loss, Surgical / veterinary; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / microbiology; Dogs; Ehrlichia canis; Ehrlichiosis / blood; Ehrlichiosis / complications; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Female; Grenada / epidemiology; Male; Partial Thromboplastin Time / veterinary; Platelet Count / veterinary; Prothrombin Time / veterinary
TL;DR: Bleeding scores in dogs coseroreactive for A. platys and E. canis may have increased intraoperative bleeding tendencies despite normal hemostatic parameters, and improved tick control is needed for dogs in Grenada. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Hyperinsulinemic Hypoglycemia Syndrome in 2 Dogs with Bartonellosis

Journal of Veterinary Internal Medicine, 28(4), 1331–1335.

By: E. Breitschwerdt n, C. Goldkamp*, W. Castleman*, J. Cullen n, P. Mascarelli n, L. Thalhem n, M. Schaer*

author keywords: Dog; Hyperinsulinemia; Hypoglycemia; Monocytosis; Seizures
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dog Diseases / physiopathology; Dogs; Hyperinsulinism / etiology; Hyperinsulinism / veterinary; Hypoglycemia / etiology; Hypoglycemia / veterinary; Male; Syndrome
TL;DR: A 6-month-old male castrated, 21-kg Weimaraner developed seizures after surgical castration and umbilical hernia repair and was referred to NCSU-CVM-VTH for further evaluation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

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