Works Published in 2011
Displaying works 41 - 60 of 124 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes
CHROMOSOME RESEARCH, 19(6), 685–708.
author keywords: B chromosomes; fragile breakage model; breakpoint reuse theory; fluorescence in situ hybridization; phylogenetic; Canidae
MeSH headings : Animals; Biological Evolution; Canidae / genetics; Chromosome Mapping; Chromosome Painting; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian / genetics; Cytogenetics; Dogs / genetics; Foxes / genetics; Genome; In Situ Hybridization, Fluorescence; Raccoon Dogs / genetics
TL;DR:
This work suggests that the complex karyotype rearrangements associated with speciation of the Canidae reflect unstable chromosome regions described by the fragile breakage model and provides evidence that these breakpoints are also recurrently associated with spontaneous canine cancers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Virtual Libraries of Tetrapyrrole Macrocycles. Combinatorics, Isomers, Product Distributions, and Data Mining
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 51(9), 2233–2247.
TL;DR:
A software program has been developed to enumerate the type and relative amounts of substituted tetrapyrrole macrocycles in a virtual library formed by one of four different classes of reactions, and Pólya's theorem (for enumeration of cyclic entities) has been implemented and provides validation for reaction classes 3 and 4.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Typical and Atypical Manifestations of Anaplasma phagocytophilum Infection in Dogs
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 47(6), E86–E94.
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasma phagocytophilum / immunology; Anaplasma phagocytophilum / isolation & purification; Animals; Antibodies, Bacterial / immunology; DNA, Bacterial / analysis; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Male; Minnesota / epidemiology; Polymerase Chain Reaction / veterinary; Retrospective Studies
TL;DR:
Treatment with doxycycline resulted in rapid resolution of clinical signs in all dogs, and fever, arthropathy, neurologic dysfunction, and epistaxis are clinical syndromes that can be associated with A phagocytophilum infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Two novel techniques to screen Abies seedlings for resistance to the balsam woolly adelgid, Adelges piceae
Journal of Insect Science (Tucson, AZ), 11.
Source: NC State University Libraries
Added: August 6, 2018
2011 article
The Potato Late Blight pathogen in Ireland, 1846: reconnecting Irish specimens with the Moore-Berkeley correspondence
Nelson, E. C., & Ristaino, J. B. (2011, October). ARCHIVES OF NATURAL HISTORY, Vol. 38, pp. 356–359.
Contributors: E. Nelson n & J. Ristaino n
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
Mastermind mutations generate a unique constellation of midline cells within the drosophila CNS
PLoS One, 6(10).
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
In Vitro Properties of a Listeria monocytogenes Bacteriophage-Resistant Mutant Predict Its Efficacy as a Live Oral Vaccine Strain
INFECTION AND IMMUNITY, 79(12), 5001–5009.
MeSH headings : Administration, Oral; Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / immunology; Bacterial Vaccines / standards; Bacteriophages / physiology; Cells, Cultured; Enterocytes / microbiology; Female; Listeria monocytogenes / genetics; Listeria monocytogenes / virology; Listeriosis / microbiology; Listeriosis / prevention & control; Mice; Mice, Inbred BALB C; Mutagenesis, Insertional; Mutation; Time Factors; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / standards
TL;DR:
The results indicate that oral administration of a profoundly attenuated listeria monocytogenes glcV mutant can safely elicit solid protective immunity.
(via Semantic Scholar)
iai.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Host immune responses that promote initial HIV spread
JOURNAL OF THEORETICAL BIOLOGY, 289, 17–35.
author keywords: HIV; Innate inflammatory response pathway; Regulatory response pathway; Mathematical model
MeSH headings : CD4-Positive T-Lymphocytes / immunology; Dendritic Cells / immunology; HIV / physiology; HIV Infections / immunology; HIV Infections / transmission; HIV Infections / virology; Humans; Inflammation / immunology; Inflammation / virology; Lymphocyte Activation / immunology; Models, Immunological; T-Lymphocytes, Regulatory / immunology; Virus Replication / immunology
TL;DR:
A model of the host inflammatory response to virus as well as inherent nTreg-mediated regulation of Th1 recruitment and activation is created to identify mechanisms of the natural inflammatory response that are best targeted to inhibit viral spread without compromising initial antiviral activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Ecological Diversity ofBartonellaSpecies Infection Among Dogs and Their Owner in Virginia
Vector-Borne and Zoonotic Diseases, 11(11), 1425–1432.
author keywords: Bacteria; Disease; Ecology; Vector
MeSH headings : Animal Husbandry; Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / transmission; Breeding; Databases, Nucleic Acid; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ecology; Female; Genotype; Humans; Polymerase Chain Reaction; Virginia
TL;DR:
Serology, serology, polymerase chain reaction, and enrichment blood culture were used to assess the prevalence of Bartonella sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
De novo synthesis and properties of analogues of the self-assembling chlorosomal bacteriochlorophylls
New Journal of Chemistry, 35(11), 2671.
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2011 journal article
Characterization of Canine Osteosarcoma by Array Comparative Genomic Hybridization and RT-qPCR: Signatures of Genomic Imbalance in Canine Osteosarcoma Parallel the Human Counterpart
GENES CHROMOSOMES & CANCER, 50(11), 859–874.
MeSH headings : Animals; Bone Neoplasms / genetics; Bone Neoplasms / veterinary; Comparative Genomic Hybridization; Core Binding Factor Alpha 1 Subunit / genetics; DNA Copy Number Variations; Dog Diseases / genetics; Dogs; Female; Gene Dosage; Genomic Instability; Humans; In Situ Hybridization, Fluorescence; Male; Membrane Proteins / genetics; Osteosarcoma / genetics; Osteosarcoma / veterinary; PTEN Phosphohydrolase / genetics; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tumor Suppressor Proteins / genetics
TL;DR:
Large scale screening of genomic imbalance in canine OS further validates the use of the dog as a suitable model for human cancers, supporting the idea that dysregulation discovered in canine cancers will provide an avenue for complementary study in human counterparts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Assessment of Lactobacillus gasseri as a Candidate Oral Vaccine Vector
CLINICAL AND VACCINE IMMUNOLOGY, 18(11), 1834–1844.
MeSH headings : Adjuvants, Immunologic / genetics; Administration, Oral; Animals; B-Lymphocytes / immunology; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / genetics; Bacterial Vaccines / immunology; Blood / immunology; Colon / immunology; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / microbiology; Drug Carriers / administration & dosage; Female; Flagellin / genetics; Genetic Vectors; Humans; Intestinal Mucosa / immunology; Lactobacillus / genetics; Lactobacillus / immunology; Mice; Mice, Inbred BALB C; Plasmids; Toll-Like Receptor 5 / immunology
TL;DR:
In vivo studies established that treatment with L. gasseri led to a diversification of B-cell populations in the lamina propria of the murine colon and a significant decrease in the percentage of FoxP3+ colonic lymphocytes, and in vivo data clarify the interaction of L. Gasseri with the host immune system and support further investigation of the in vivo immunogenicity of the vector.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
A trans-AB-Bacteriochlorin Building Block
JOURNAL OF ORGANIC CHEMISTRY, 76(22), 9478–9487.
MeSH headings : Acetals / chemical synthesis; Acetals / chemistry; Catalysis; Halogenation; Molecular Structure; Photochemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Pyrroles / chemistry
TL;DR:
Four new results are reported concerning the synthesis of substituted bacteriochlorins, including a new, scalable route to 1,1-dimethoxy-4-methylpent-3-en-2-one, which afford deeper understanding of the scope and limitations of the de novo route and also advance the capabilities for tailoring synthetic bacterio chlorins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Photophysical Properties and Electronic Structure of Stable, Tunable Synthetic Bacteriochlorins: Extending the Features of Native Photosynthetic Pigments
JOURNAL OF PHYSICAL CHEMISTRY B, 115(37), 10801–10816.
MeSH headings : Bacteriochlorophylls / chemistry; Electrons; Pheophytins / chemistry; Photosynthesis; Porphyrins / chemical synthesis; Porphyrins / chemistry; Quantum Theory; Spectroscopy, Near-Infrared
TL;DR:
The studies show how the palette of synthetic bacteriochlorins extends the properties of the native photosynthetic pigments (bacteriochlorophylls) and elucidated design principles for tuning the spectral and photophysical characteristics as required for a wide variety of photochemical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
A bifunctional allosteric site in the dimer interface of procaspase-3
BIOPHYSICAL CHEMISTRY, 159(1), 100–109.
author keywords: Caspase; Apoptosis; Allosteric activator; Drug design; Cancer therapy
MeSH headings : Allosteric Site; Caspase 3 / chemistry; Caspase 3 / metabolism; Enzyme Activation / drug effects; Humans; Models, Molecular; Protein Binding; Protein Multimerization; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
TL;DR:
This work has utilized the allosteric site of caspase-3 to identify a small molecule activator of procaspase and to characterize its binding to the protease, and suggests that an efficient activator must stabilize the active conformer of the zymogen by expelling the intersubunit linker from the interface.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Evolution of the Max and Mlx Networks in Animals
GENOME BIOLOGY AND EVOLUTION, 3, 915–937.
author keywords: protein evolution; basic-helix-loop-helix-leucine zipper (bHLHZ) domain; Myc/Max/Mad network; Mlx and Mondo Network; phylogenetic tree; discriminant analysis
MeSH headings : Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / chemistry; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics; Basic-Leucine Zipper Transcription Factors / classification; Basic-Leucine Zipper Transcription Factors / genetics; Binding Sites; Evolution, Molecular; Gene Expression Regulation; Gene Regulatory Networks / genetics; Humans; Molecular Sequence Data; Multigene Family; Phylogeny; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Synteny / genetics
TL;DR:
These analyses on Max and Mlx network members provide a model for characterizing the evolution of TFs involved in essential networks, and identify clear relationships among protein families with distinct points of radiation and divergence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Bartonella Species Bacteremia in Two Patients with Epithelioid Hemangioendothelioma
Journal of Clinical Microbiology, 49(11), 4006–4012.
MeSH headings : Adult; Bacteremia / diagnosis; Bacteremia / microbiology; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Female; Hemangioendothelioma, Epithelioid / complications; Hemangioendothelioma, Epithelioid / diagnosis; Humans; Male; Middle Aged
TL;DR:
Chronic Bartonella infection could have a role in the development of this vascular neoplasm, considering the biology and clinically variable natural history of epithelioid hemangioendothelioma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2011 journal article
Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression
AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.
MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
TL;DR:
A similarity-based regression method for assessing the main genetic and interaction effects of a group of markers on quantitative traits and is an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium blocks, genes, or pathways in whole-genome analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 review
Molecules for Charge-Based Information Storage
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 44(8), 638–650.
TL;DR:
This Account surveys more than a decade of results from research programs to employ porphyrin molecules as charge-storage elements in hybrid semiconductor-molecular dynamic random access memory, indicating the superior features of selected molecular architectures for molecular electronics applications.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach
BONE, 49(3), 356–367.
author keywords: Osteosarcoma; Gene expression profiling; Cell cycle; DNA damage checkpoint; Tumor microenvironment; Canine
MeSH headings : Animals; Bone Neoplasms / classification; Bone Neoplasms / genetics; Bone Neoplasms / pathology; Cluster Analysis; Cohort Studies; Cyclin B2 / genetics; Cyclin B2 / metabolism; Dogs; Female; Gene Expression Profiling; Humans; Kaplan-Meier Estimate; Male; Oligonucleotide Array Sequence Analysis / methods; Osteosarcoma / classification; Osteosarcoma / genetics; Osteosarcoma / pathology; Prognosis; Vimentin / genetics; Vimentin / metabolism
TL;DR:
The results indicate that the narrower genetic diversity of dogs can be utilized to group complex human osteosarcoma into biologically and clinically relevant molecular subtypes, which in turn may enhance prognosis and prediction, and identify relevant therapeutic targets.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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