Works Published in 2014
Displaying works 41 - 60 of 101 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma
CHROMOSOME RESEARCH, 22(3), 305–319.
author keywords: canine; chromosome; hemangiosarcoma; comparative genomic hybridization (CGH)
MeSH headings : Animals; Breeding; Comparative Genomic Hybridization; DNA Copy Number Variations / genetics; Dog Diseases / genetics; Dogs; Gene Amplification; Gene Expression Profiling; Genetic Heterogeneity; Genome; Hemangiosarcoma / genetics; Hemangiosarcoma / veterinary; Penetrance; Vascular Endothelial Growth Factor A / genetics
TL;DR:
Analysis of genome-wide microarray-based somatic DNA copy number profiling of 75 primary intra-abdominal hemangiosarcomas from five popular dog breeds supports prior transcriptional studies suggesting that the clinical heterogeneity of this cancer may reflect the existence of multiple, molecularly distinct subtypes of canine hemangiusarcoma.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Establishing ion ratio thresholds based on absolute peak area for absolute protein quantification using protein cleavage isotope dilution mass spectrometry
ANALYST, 139(21), 5439–5450.
MeSH headings : Chromatography, Liquid; Isotopes / chemistry; Proteins / analysis; Tandem Mass Spectrometry / methods
TL;DR:
It is suggested that evaluation of the absolute ion abundance for any given transition is necessary in order to effectively implement RA thresholds, and these RA values should be assessed as close as possible to the time at which data is collected for quantification.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Enhanced Light-Harvesting Capacity by Micellar Assembly of Free Accessory Chromophores and LH1-like Antennas
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 90(6), 1264–1276.
MeSH headings : Energy Transfer; Light-Harvesting Protein Complexes / chemistry; Micelles; Spectroscopy, Fourier Transform Infrared
TL;DR:
The use of free accessory chromophores affords a simple design to enhance the overall light‐harvesting capacity of biohybrid LH1‐like architectures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Detection of Bartonella Species in the Blood of Veterinarians and Veterinary Technicians: A Newly Recognized Occupational Hazard?
Vector-Borne and Zoonotic Diseases, 14(8), 563–570.
author keywords: Bartonella; Diagnostic test; Veterinarian; Zoonosis; Bacteremia
TL;DR:
This study supports an emerging body of evidence that cryptic Bartonella bloodstream infection may be more frequent in humans than previously recognized and may induce symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Bartonella henselae Infections In An Owner and Two Papillon Dogs Exposed to Tropical Rat Mites (Ornithonyssus bacoti)
Vector-Borne and Zoonotic Diseases, 14(10), 703–709.
author keywords: Neuropsychiatric symptoms; Mites; Vector; Pruritis; Edema
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Doxycycline / therapeutic use; Female; Humans; Male; Mite Infestations / parasitology; Mites / microbiology; Polymerase Chain Reaction; Pruritus / drug therapy; Pruritus / microbiology; Pruritus / veterinary; Rats; Sequence Analysis, DNA; Zoonoses
TL;DR:
Clinicians and vector biologists should consider the possibility that rat mites may play a role in Bartonella spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae
Journal of Clinical Microbiology, 52(9), 3447–3452.
Ed(s): E. Munson
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Diarrhea / microbiology; Diarrhea / pathology; Diarrhea / veterinary; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Flea Infestations / complications; Flea Infestations / veterinary; Male; Prostatitis / diagnosis; Prostatitis / microbiology; Prostatitis / pathology; Steatitis / microbiology; Steatitis / pathology
TL;DR:
A dog developed an unusual clinical presentation for canine bartonellosis following an acute flea infestation, and comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
Co-infection with Anaplasma platys, Bartonella henselae, Bartonella koehlerae and ‘Candidatus Mycoplasma haemominutum’ in a cat diagnosed with splenic plasmacytosis and multiple myeloma
Journal of Feline Medicine and Surgery, 16(8), 713–720.
MeSH headings : Animals; Bartonella Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cats; Coinfection; Doxycycline / therapeutic use; Multiple Myeloma / diagnosis; Multiple Myeloma / drug therapy; Multiple Myeloma / veterinary; Mycoplasma Infections / drug therapy; Mycoplasma Infections / veterinary; Polymerase Chain Reaction / veterinary
TL;DR:
Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
SnRK1 Phosphorylation of AL2 Delays Cabbage Leaf Curl Virus Infection in Arabidopsis
JOURNAL OF VIROLOGY, 88(18), 10598–10612.
MeSH headings : Amino Acid Sequence; Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis / virology; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Begomovirus / chemistry; Begomovirus / classification; Begomovirus / genetics; Begomovirus / metabolism; Host-Pathogen Interactions; Molecular Sequence Data; Phylogeny; Plant Diseases / virology; Protein Binding; Protein Kinases / genetics; Protein Kinases / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Viral Proteins / chemistry; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
It is shown that the host protein kinase SnRK1, a central regulator of energy balance and nutrient metabolism in plants, phosphorylates serine-109 in AL2 proteins of three subgroups of New World begomoviruses, resulting in a delay in viral DNA accumulation and symptom appearance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 personal communication
Response to letter from J Mottet "Comments on the ISCAID Guidelines on the use of antimicrobial therapies in canine superficial bacterial folliculitis"
Lloyd, D. H., Weese, J. S., Blondeau, J. M., Boothe, D., Breitschwerdt, E., Guardabassi, L., … al. (2014, December).
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / diagnosis; Folliculitis / veterinary; Skin Diseases, Bacterial / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Pathway-Guided Identification of Gene-Gene Interactions
ANNALS OF HUMAN GENETICS, 78(6), 478–491.
author keywords: Pathway analysis; gene-gene interactions; bio-knowledge-guided
MeSH headings : Computer Simulation; Epistasis, Genetic; Genotype; Humans; Linear Models; Models, Genetic; Polymorphism, Single Nucleotide; Principal Component Analysis; Regression Analysis
TL;DR:
A regression model with pathway‐guided regularization for detecting interactions among genes using the principal components to summarize the SNP‐SNP interactions between a gene pair, and an L1 penalty that incorporates adaptive weights based on biological guidance and trait supervision to identify important main and interaction effects is proposed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Mapping epistatic quantitative trait loci
BMC GENETICS, 15.
author keywords: Quantitative trait loci; Epistasis; Model selection; Sequential search
MeSH headings : Algorithms; Chromosome Mapping / methods; Epistasis, Genetic; Lod Score; Models, Genetic; Quantitative Trait Loci
TL;DR:
This paper developed a three-stage search strategy that provides an effective and powerful solution to map multiple QTL with complex epistatic pattern and has been implemented in the user-friendly computer software Windows QTL Cartographer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Development and Validation of a Sensitive and Specific sodB-Based Quantitative PCR Assay for Molecular Detection of Ehrlichia Species
JOURNAL OF CLINICAL MICROBIOLOGY, 52(11), 4030–4032.
MeSH headings : Animals; Bacterial Proteins / genetics; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dogs; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Humans; Molecular Sequence Data; RNA, Ribosomal, 16S / genetics; Real-Time Polymerase Chain Reaction / methods; Sensitivity and Specificity; Sequence Analysis, DNA; Superoxide Dismutase / genetics
TL;DR:
A sensitive and specific sodB-based quantitative PCR assay to detect Ehrlichia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Canine Prostate Cancer Cell Line (Probasco) Produces Osteoblastic Metastases In Vivo
PROSTATE, 74(13), 1251–1265.
author keywords: prostate cancer; osteoblastic metastases; canine; dog
MeSH headings : Animals; Biomarkers, Tumor / genetics; Biomarkers, Tumor / metabolism; Bone Neoplasms / genetics; Bone Neoplasms / metabolism; Bone Neoplasms / secondary; Carcinoma / genetics; Carcinoma / metabolism; Carcinoma / secondary; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dogs; Male; Mice; Mice, Nude; Neoplasm Transplantation; Osteoblasts / metabolism; Osteoblasts / pathology; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology
TL;DR:
This study established and characterized a novel canine prostate cancer cell line that will contribute to the understanding of prostate cancer pathogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Amphiphilic, hydrophilic, or hydrophobic synthetic bacteriochlorins in biohybrid light-harvesting architectures: consideration of molecular designs
PHOTOSYNTHESIS RESEARCH, 122(2), 187–202.
author keywords: Light harvesting; Photosynthetic antenna; Energy transfer; Bacteriochlorin; Bacteriochlorophyll; Bioconjugate; Dyad; Self-assembly
MeSH headings : Bioelectric Energy Sources; Light; Light-Harvesting Protein Complexes / chemistry; Models, Molecular; Porphyrins / chemistry; Protein Conformation
TL;DR:
In terms of handling, assembly and energy-transfer efficiency taken together, the amphiphilic design examined herein is more attractive than the prior hydrophilic or hydrophobic designs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Versatile design of biohybrid light-harvesting architectures to tune location, density, and spectral coverage of attached synthetic chromophores for enhanced energy capture
PHOTOSYNTHESIS RESEARCH, 121(1), 35–48.
author keywords: Light harvesting; Photosynthetic antenna; Energy transfer; Bacteriochlorin; Bacteriochlorophyll; Bioconjugate; Self-assembly; LH1
MeSH headings : Bacteriochlorophylls / chemistry; Bacteriochlorophylls / genetics; Bacteriochlorophylls / metabolism; Light-Harvesting Protein Complexes / chemistry; Light-Harvesting Protein Complexes / genetics; Light-Harvesting Protein Complexes / metabolism; Protein Structure, Secondary; Rhodobacter sphaeroides / chemistry; Rhodobacter sphaeroides / genetics; Rhodobacter sphaeroides / metabolism
TL;DR:
Three new designs, each of which employs analogs of the β-polypeptide from Rhodobacter sphaeroides, have been investigated, and illustrate the great latitude of the biohybrid approach for the design of diverse light-harvesting systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Statistical considerations on the formation of circular photosynthetic light-harvesting complexes from Rhodopseudomonas palustris
PHOTOSYNTHESIS RESEARCH, 121(1), 49–60.
author keywords: Bacterial photosynthesis; Light-harvesting; Heterogeneous; Oligomer; Diversity; Simulation; Self-assembly
MeSH headings : Bacteriochlorophylls / chemistry; Bacteriochlorophylls / metabolism; Light-Harvesting Protein Complexes / chemistry; Light-Harvesting Protein Complexes / metabolism; Photosynthesis / physiology; Rhodopseudomonas / chemistry; Rhodopseudomonas / metabolism
TL;DR:
The software program Cyclaplex, which enables generation and data-mining of virtual libraries of molecular rings formed upon combinatorial reactions, has been used to delineate the possible number and type of distinct nonamers as a function of numbers of distinct protomers.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Experimental infection of cats with Afipia felis and various Bartonella species or subspecies
Veterinary Microbiology, 172(3-4), 505–510.
author keywords: Bartonella; Afipia felis; Cats; Experimental infection; Zoonosis
MeSH headings : Afipia; Animals; Bacteremia / veterinary; Bartonella / classification; Bartonella / genetics; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; Gram-Negative Bacterial Infections / veterinary; Polymerase Chain Reaction
TL;DR:
Most of the cats seroconverted, but only the cats inoculated with B. rochalimae became bacteremic, indicating that cats are not natural hosts of A. felis or the other Bartonella species or subspecies tested in this study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2014 journal article
A simple improved-throughput xylem protoplast system for studying wood formation
NATURE PROTOCOLS, 9(9), 2194–2205.
MeSH headings : Cell Wall / metabolism; Gene Expression Regulation, Plant / genetics; Gene Regulatory Networks / genetics; Green Fluorescent Proteins; Populus / cytology; Populus / growth & development; Protoplasts / metabolism; Transfection / methods; Wood / cytology; Wood / growth & development; Xylem / chemistry
TL;DR:
A protocol for the isolation and transfection of protoplasts from wood-forming tissue, the stem-differentiating xylem (SDX), in the model woody plant Populus trichocarpa is presented.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
A robust chromatin immunoprecipitation protocol for studying transcription factor-DNA interactions and histone modifications in wood-forming tissue
NATURE PROTOCOLS, 9(9), 2180–2193.
MeSH headings : Base Sequence; Chromatin Immunoprecipitation / methods; DNA / metabolism; DNA Fragmentation; Histones / metabolism; Immunoprecipitation; Molecular Sequence Data; Populus / cytology; Populus / metabolism; Sequence Analysis, DNA; Transcription Factors / metabolism; Wood / cytology; Xylem / genetics; Xylem / metabolism
TL;DR:
This protocol is the only working ChIP system for wood-forming tissue and uses stem-differentiating xylem to identify genome-wide specific TF-DNA interactions during wood formation and histone modifications associated with regulation of wood formation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Serological and molecular prevalence of selected canine vector borne pathogens in blood donor candidates, clinically healthy volunteers, and stray dogs in North Carolina
Parasites & Vectors, 7(1), 116.
author keywords: Healthy dogs; CVBDs; Co-infection; Blood donors
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Blood Donors; Dog Diseases / blood; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Insect Vectors; Male; North Carolina / epidemiology; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / epidemiology; Prevalence; Seroepidemiologic Studies; Serologic Tests
TL;DR:
To screen healthy dogs for serological and molecular evidence of regionally important CVBDs, serum and ethylenediamine tetraacetic acid anti-coagulated blood specimens collected from each dog were tested for CVBD pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
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