Works Published in 2016
Displaying works 41 - 60 of 79 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Single-Site Glycoprotein Mutants Inhibit a Late Event in Sindbis Virus Assembly
JOURNAL OF VIROLOGY, 90(18), 8372–8380.
MeSH headings : Animals; Cells, Cultured; Cricetinae; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Microscopy, Electron; Mutant Proteins / genetics; Mutant Proteins / metabolism; Mutation, Missense; Point Mutation; Sequence Deletion; Sindbis Virus / genetics; Sindbis Virus / physiology; Sindbis Virus / ultrastructure; Suppression, Genetic; Temperature; Viral Envelope Proteins / genetics; Viral Envelope Proteins / metabolism; Viral Load; Virion / ultrastructure; Virus Assembly; Virus Cultivation; Virus Release
TL;DR:
It is concluded that H230 is essential for the assembly of complete infectious Sindbis virus virions and that the presence of an amino acid at E2 position 209 is required for complete budding of Sind Bis virus particles although several different amino acids can be at this location without affecting the titer.
(via Semantic Scholar)
jvi.asm.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Quantitative trait loci influencing forking defects in an outbred pedigree of loblolly pine
BMC GENETICS, 17.
author keywords: QTL; Stem forking; Outbred; Pinus taeda; MAS; Tree breeding; Wood quality
MeSH headings : Algorithms; Breeding; Chromosome Mapping; Genetic Association Studies; Genetic Linkage; Genetic Markers; Genotype; Models, Statistical; Pedigree; Phenotype; Pinus taeda / genetics; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Quantitative Trait, Heritable
TL;DR:
The hypothesis that marker-assisted selection can be used to decrease the rate of stem defects in breeding populations of loblolly pine is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Photophysical comparisons of PEGylated porphyrins, chlorins and bacteriochlorins in water
NEW JOURNAL OF CHEMISTRY, 40(11), 9648–9656.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny
PLOS ONE, 11(11).
Contributors: M. Schreeg n, H. Marr n, J. Tarigo n, L. Cohn*, D. Bird n , E. Scholl n, M. Levy n, B. Wiegmann n , A. Birkenheuer n
MeSH headings : DNA, Protozoan / genetics; Genome, Mitochondrial; Humans; Phylogeny; Piroplasmida / classification; Piroplasmida / genetics; Protozoan Infections / parasitology
TL;DR:
Phylogenetic analysis of concatenated mitochondrial and 18S sequences as well as cox1 amino acid sequence identified five distinct Piroplasmida groups, each of which possesses a unique mitochondrial genome structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Infective endocarditis in 13 cats
Journal of Veterinary Cardiology, 18(3), 213–225.
author keywords: BAPGM; Bartonella; Duke criteria; Vegetative lesion
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / physiopathology; Endocarditis, Bacterial / veterinary; Female; Male; Prognosis; Retrospective Studies; Treatment Outcome
TL;DR:
In contrast to dogs, cats with IE typically present with clinical signs consistent with cardiac decompensation and locomotor abnormalities suggestive of either thromboembolic disease or inflammatory arthritis, and prognosis is grave.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
First Report of Gummosis Caused by Phytophthora frigida on Black Wattle in Brazil
Plant Disease, 100(11), 2336–2336.
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Complexity in structure-directed prebiotic chemistry. Unexpected compositional richness from competing reactants in tetrapyrrole formation
NEW JOURNAL OF CHEMISTRY, 40(7), 6421–6433.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Complexity in structure-directed prebiotic chemistry. Reaction bifurcation from a beta-diketone in tetrapyrrole formation
NEW JOURNAL OF CHEMISTRY, 40(7), 6434–6440.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 review
Use of bacteriophage to target bacterial surface structures required for virulence: a systematic search for antibiotic alternatives
[Review of ]. CURRENT GENETICS, 62(4), 753–757.
author keywords: Bacteriophage; Phage; Receptor; Attenuation; Therapy; Antibiotic; Alternative; Antivirulence factor
MeSH headings : Animals; Anti-Bacterial Agents / biosynthesis; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Bacteria / pathogenicity; Bacteria / virology; Bacterial Infections / microbiology; Bacterial Physiological Phenomena; Bacteriophages / physiology; Cell Membrane / metabolism; Drug Discovery; Humans; Receptors, Virus / metabolism; Virulence
TL;DR:
Examples of how mutations that confer phage resistance produce attenuation are covered, and how this coincidental relationship can be exploited in the search for the next generation of therapeutic agents for bacterial diseases are covered.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Transcriptome sequencing of Mycosphaerella fijiensis during association with Musa acuminata reveals candidate pathogenicity genes
BMC GENOMICS, 17.
author keywords: Mycosphaerella fijiensis; Black Sigatoka; Transcriptome; Effectors; Secondary metabolism; Non-ribosomal peptide synthase; Fusicoccane; Domain of Unknown Function 3328; Salicylate hydroxylase; Dispensable chromosome
MeSH headings : Ascomycota / genetics; Ascomycota / pathogenicity; Fungal Proteins / biosynthesis; Fungal Proteins / genetics; High-Throughput Nucleotide Sequencing; Molecular Sequence Annotation; Musa / genetics; Musa / microbiology; Plant Diseases / genetics; Plant Diseases / microbiology; Plant Leaves / genetics; Plant Leaves / microbiology; Transcriptome / genetics; Virulence / genetics
TL;DR:
Major changes are revealed in the transcriptome of Mycosphaerella fijiensis, when associating with its host compared to during saprophytic growth in medium, and this analysis identified putative pathogenicity genes and also provides support for the existence of dispensable chromosomes in this fungus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Artificial selection on chill-coma recovery time in Drosophila melanogaster: Direct and correlated responses to selection
JOURNAL OF THERMAL BIOLOGY, 59, 77–85.
author keywords: Cross-tolerance; Chill-coma recovery; Drosophila melanogaster; Artificial selection
MeSH headings : Acclimatization; Animal Nutritional Physiological Phenomena; Animals; Breeding; Cold Temperature; Cold-Shock Response; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Male; Phenotype; Selection, Genetic; Stress, Physiological
TL;DR:
The results suggest that although artificial selection has dramatically altered chill-coma recovery time, the correlated response to selection on other stress response phenotypes has been negligible, and the lack of a correlated response suggests that chill- COMA recovery time in these selection lines is likely genetically independent from measures of cold survivorship tested here.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(34), E5014–E5023.
author keywords: comparative genomics; proteasome and TAP evolution; major histocompatibility; MHC class I pathway; CG2 clonal zebrafish
MeSH headings : Animals; Antigen Presentation; Biological Evolution; Cloning, Organism; Cysteine Endopeptidases / classification; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / immunology; Genome; Haplotypes; High-Throughput Nucleotide Sequencing; Histocompatibility Antigens Class I / classification; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Phylogeny; Proteasome Endopeptidase Complex / genetics; Proteasome Endopeptidase Complex / immunology; Protein Isoforms / classification; Protein Isoforms / genetics; Protein Isoforms / immunology; Transcriptome; Zebrafish / classification; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / classification; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
Comparison analysis shows that antigen processing gene diversity is far more extensive than previously realized, implying distinct immune functions and conserved roles in shaping MHC pathway evolution throughout vertebrates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Vertical transmission of Anaplasma platys and Leishmania infantum in dogs during the first half of gestation
Parasites & Vectors, 9(1).
author keywords: Vertical transmission; Leishmania infantum; Anaplasma platys; Dog; Real-time PCR
MeSH headings : Anaplasma / genetics; Anaplasma / isolation & purification; Anaplasma / physiology; Anaplasmosis / parasitology; Anaplasmosis / transmission; Animals; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Female; Infectious Disease Transmission, Vertical / veterinary; Italy; Leishmania infantum / genetics; Leishmania infantum / immunology; Leishmania infantum / isolation & purification; Leishmania infantum / physiology; Leishmaniasis, Visceral / parasitology; Leishmaniasis, Visceral / transmission; Leishmaniasis, Visceral / veterinary; Ovary / microbiology; Ovary / parasitology; Pregnancy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / parasitology; Pregnancy Complications, Infectious / veterinary; Uterus / microbiology; Uterus / parasitology
TL;DR:
Results from this study suggest that, in contrast to L. infantum, A. platys can be transmitted from pregnant dogs to their offspring during the first half of gestation, and this hypothesis remains to be verified, for instance via direct observation of parasites in postpartum foetal tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Vasculitis, cerebral infarction and persistent Bartonella henselae infection in a child
Parasites & Vectors, 9(1).
author keywords: Neurobartonellosis; Bartonella henselae San Antonio 2 vasculitis
MeSH headings : Bacteremia; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Brain / microbiology; Brain / pathology; Canada; Cerebral Infarction / diagnosis; Cerebral Infarction / etiology; Child; Female; Humans; Sequence Analysis, DNA; Vasculitis / complications; Vasculitis / diagnosis; Vasculitis / microbiology
TL;DR:
B. henselae bacteremia, potentially spanning a 12-year time frame, in conjunction with the therapeutic administration of immunosuppressive drugs may have resulted in a progression and potentiation of the neurological disease that was partially reversible following antibiotic administration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy
AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(7), 693–699.
MeSH headings : Animals; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / metabolism; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Down-Regulation; Female; Gene Expression; Heart Ventricles; Male; Myocardium / metabolism; RNA / genetics; Up-Regulation
TL;DR:
Genes involved in cellular energy metabolism, especially metabolism of carbohydrates and fats, were significantly downregulated in dogs with DCM, and Expression of cardiac structural proteins was also altered in affected dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
The confounding complexity of innate immune receptors within and between teleost species
FISH & SHELLFISH IMMUNOLOGY, 53, 24–34.
author keywords: Gene content haplotype; Novel immune-type receptors; Diverse immunoglobulin domain containing proteins; Polymeric immunoglobulin receptor-like proteins; Novel immunoglobulin-like transcripts
MeSH headings : Animals; Fishes / genetics; Fishes / immunology; Genetic Variation; Genome; Immunity, Innate; Receptors, Immunologic / genetics
TL;DR:
By defining which teleost lineages encode (and do not encode) different IIir families, predictions can be made about the presence (or absence) of specific IIIR families in each teleost lineage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Expression of a constitutively active nitrate reductase variant in tobacco reduces tobacco-specific nitrosamine accumulation in cured leaves and cigarette smoke
PLANT BIOTECHNOLOGY JOURNAL, 14(7), 1500–1510.
author keywords: nitrate reductase; tobacco; tobacco-specific nitrosamines; burley; nitrogen-assimilation pathway; NNN; NNK
MeSH headings : Carcinogens / metabolism; Metabolic Networks and Pathways; Nitrate Reductase / genetics; Nitrates / metabolism; Nitrogen / metabolism; Nitrosamines / metabolism; Plant Leaves / genetics; Plant Leaves / metabolism; Plants, Genetically Modified / metabolism; Tobacco / genetics; Tobacco / metabolism; Tobacco Products
TL;DR:
Investigation of the potential of molecular genetic strategies to lower nitrate levels in burley tobaccos by overexpressing genes encoding key enzymes of the nitrogen‐assimilation pathway found only the expression of a constitutively active nitrate reductase (NR) dramatically decreased free nitrates levels in the leaves.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Evaluation of silver-titanium implants activated by low intensity direct current for orthopedic infection control: An in vitro and in vivo study
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 104(5), 1023–1031.
author keywords: prosthetic infection; oligodynamic silver; antimicrobial implant; electrical activation
MeSH headings : Animals; Female; Femur / microbiology; Femur / surgery; Implants, Experimental; Rats; Rats, Sprague-Dawley; Silver / chemistry; Silver / pharmacology; Staphylococcal Infections / prevention & control; Staphylococcus aureus / growth & development; Titanium / chemistry; Titanium / pharmacology
TL;DR:
In vivo, none of the four groups were able to prevent wound infection, but the experimental group resulted in reduced colonization, and the antimicrobial potential of LIDC-activated Ag-Ti implants is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Detection of Copy Number Imbalance in Canine Urothelial Carcinoma With Droplet Digital Polymerase Chain Reaction
VETERINARY PATHOLOGY, 53(4), 764–772.
author keywords: comparative genomic hybridization; cytogenetics; dogs; molecular diagnostic; transitional cell carcinoma; polymerase chain reaction; urinary bladder; urothelial carcinoma
MeSH headings : Animals; Carcinoma, Transitional Cell / diagnosis; Carcinoma, Transitional Cell / genetics; Carcinoma, Transitional Cell / pathology; Carcinoma, Transitional Cell / veterinary; Comparative Genomic Hybridization / veterinary; DNA Copy Number Variations; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Polymerase Chain Reaction / veterinary; Urinary Bladder / pathology; Urinary Bladder Neoplasms / diagnosis; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / pathology; Urinary Bladder Neoplasms / veterinary; Urologic Neoplasms / diagnosis; Urologic Neoplasms / genetics; Urologic Neoplasms / pathology; Urologic Neoplasms / veterinary
TL;DR:
The findings show that ddPCR is a useful molecular technique to detect CNAs and may be used as a noninvasive molecular diagnostic test for canine UC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Two Novel DNAs That Enhance Symptoms and Overcome CMD2 Resistance to Cassava Mosaic Disease
JOURNAL OF VIROLOGY, 90(8), 4160–4173.
TL;DR:
The discovery of two novel DNA sequences, designated SEGs-1 and SEGS-2 (for sequences enhancing geminivirus symptoms), that enhance symptoms and break resistance to CMD have major implications for the long-term durability of CMD2 resistance and underscore the need for alternative sources of resistance in cassava.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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