Works Published in 2020

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Displaying works 41 - 60 of 73 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

Crystal Structure of 1,9-Dibromo-5-phenyldipyrrin, Tetrapyrrole Synthesis Derivative and Free Base Ligand of BODIPY Building Blocks

X-RAY STRUCTURE ANALYSIS ONLINE, 36, 21–22.

Sources: Web Of Science, ORCID
Added: August 3, 2020

2020 journal article

Infection by cyst nematodes induces rapid remodelling of developing xylem vessels in wheat roots

SCIENTIFIC REPORTS, 10(1).

MeSH headings : Animals; Cell Wall / metabolism; Cysts / metabolism; Gene Expression Regulation, Plant / genetics; Giant Cells / cytology; Infections; Microscopy, Confocal / methods; Nematoda / metabolism; Nematode Infections / metabolism; Nematode Infections / physiopathology; Plant Diseases / parasitology; Plant Roots / metabolism; Plant Roots / parasitology; Triticum / metabolism; Triticum / parasitology; Tylenchoidea / parasitology; Tylenchoidea / physiology; Xylem / cytology
TL;DR: By interfering with a developmental program that normally leads to programmed cell death, H. avenae may permit xylem vessel elements to remain alive for later exploitation by the parasite. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 20, 2020

2020 journal article

Imaging analysis of Bartonella species in the skin using single‐photon and multi‐photon (second harmonic generation) laser scanning microscopy

Clinical Case Reports.

By: A. Maluki*, E. Breitschwerdt n, L. Bemis*, R. Greenberg*, B. Mozayeni, J. Dencklau*, M. Ericson*

author keywords: Bartonella; confocal microscopy; psychiatric disorders; second harmonic generation; striae distensae
TL;DR: It is demonstrated Bartonella spp are abundant in skin lesions resembling striae distensae, coincidental with sudden onset of neuropsychiatric symptoms, indicate testing for suspected Bartonelli spp. (via Semantic Scholar)
Source: ORCID
Added: July 20, 2020

2020 journal article

Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 54(12), 7409–7419.

MeSH headings : Animals; Biomarkers; Dogs; Environmental Monitoring; Humans; Organophosphates; Silicones
TL;DR: Exposures among pet dogs and their owners using silicone dog tags and wristbands were evaluated to determine if contaminant levels were correlated with validated biomarkers and the value of using silicone bands with dogs to investigate health impacts on humans from shared exposures is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: July 13, 2020

2020 journal article

Arabidopsis DNA Replication Initiates in Intergenic, AT-Rich Open Chromatin(1)([OPEN])

PLANT PHYSIOLOGY, 183(1), 206–220.

By: E. Wheeler n, A. Brooks n, L. Concia n, D. Vera*, E. Wear n, C. LeBlanc*, U. Ramu*, M. Vaughn ...

MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Chromatin / metabolism; DNA Replication / genetics; DNA Replication / physiology; DNA, Plant / metabolism; DNA, Plant / physiology; Replication Origin / genetics; Replication Origin / physiology
TL;DR: A new functional assay to label and map very early replicating loci that must, by definition, include at least a subset of replication origins, and indicates that IRs are associated with accessible chromatin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 15, 2020

2020 journal article

Equiprobable discrete models of site-specific substitution rates underestimate the extent of rate variability

PLOS ONE, 15(3).

By: F. Mannino n, S. Wisotsky n, S. Pond* & S. Muse n

MeSH headings : Algorithms; Amino Acid Substitution; Evolution, Molecular; Likelihood Functions; Models, Genetic; Mutation Rate; Phylogeny; Sequence Alignment; Sequence Analysis, DNA / methods
TL;DR: It is demonstrated that the variance of this discretized distribution has an upper bound determined solely by the choice of K and the mean of the distribution, which can introduce biases into statistical inference when estimating parameters governing site-to-site variability of substitution rates. (via Semantic Scholar)
Source: Web Of Science
Added: June 15, 2020

2020 review

Riley Oxidation of Heterocyclic Intermediates on Paths to Hydroporphyrins-A Review

[Review of ]. MOLECULES, 25(8).

By: P. Wang n & J. Lindsey n

author keywords: aldehyde; bacteriochlorin; chlorin; dihydrodipyrrin; dipyrromethane; selenium dioxide; selenium reagent; tetrahydrodipyrrin
MeSH headings : Heterocyclic Compounds / chemistry; Molecular Structure; Oxidation-Reduction; Porphyrins / chemistry
TL;DR: In general, Riley oxidation of dihydrodipyrrins has a broad scope toward substituents, but proceeds in only modest yield, and new reaction conditions or approaches will be required to achieve high yields for this critical transformation in the synthesis of hydroporphyrins. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 15, 2020

2020 journal article

Engineering Cercospora disease resistance via expression of Cercospora nicotianae cercosporin-resistance genes and silencing of cercosporin production in tobacco

PLOS ONE, 15(3).

By: E. Thomas n, S. Herrero n, H. Eng n, N. Gomaa n, J. Gillikin n, R. Noar n, A. Beseli n, M. Daub n

MeSH headings : Ascomycota / drug effects; Ascomycota / genetics; Disease Resistance / drug effects; Disease Resistance / genetics; Drug Resistance, Fungal / drug effects; Drug Resistance, Fungal / genetics; Gene Expression Regulation, Fungal / drug effects; Gene Silencing / drug effects; Genes, Fungal; Genetic Engineering; Perylene / analogs & derivatives; Perylene / pharmacology; Plants, Genetically Modified; Tobacco / microbiology; Transformation, Genetic; Transgenes
TL;DR: It is concluded that expression of fungal cercosporin autoresistance genes as well as silencing of the cercsporin pathway are both effective strategies for engineering resistance to Cercospora diseases where cercOSporin plays a critical role. (via Semantic Scholar)
Source: Web Of Science
Added: June 8, 2020

2020 journal article

Use of standardized bioinformatics for the analysis of fungal DNA signatures applied to sample provenance

FORENSIC SCIENCE INTERNATIONAL, 310.

author keywords: Forensic microbiology; Bioinformatics; Metabarcoding; Sample provenance
MeSH headings : DNA Barcoding, Taxonomic; DNA, Fungal / chemistry; Demography; Forensic Sciences; Fungi; Humans; Reference Values; Soil
TL;DR: Investigating a small-scale approach as an adaptation of a larger metabarcoding study to develop a model for global sample provenance using fungal DNA signatures collected from dust swabs to facilitate a standardized method for consistent, reproducible sample treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 26, 2020

2020 journal article

Cotton leaf curl Multan virus beta C1 Protein Induces Autophagy by Disrupting the Interaction of Autophagy-Related Protein 3 with Glyceraldehyde-3-Phosphate Dehydrogenases([OPEN])

PLANT CELL, 32(4), 1124–1135.

By: A. Ismayil*, M. Yang*, Y. Haxim*, Y. Wang*, J. Li*, L. Han*, Y. Wang*, X. Zheng* ...

MeSH headings : Autophagy; Autophagy-Related Proteins / metabolism; Begomovirus / metabolism; Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism; Plant Proteins / metabolism; Protein Binding; Tobacco / metabolism; Tobacco / ultrastructure; Tobacco / virology; Vacuoles / metabolism; Vacuoles / ultrastructure; Viral Proteins / metabolism
TL;DR: It is reported that the βC1 protein of Cotton leaf curl Multan betasatellite (CLCuMuB) interacts with cytosolic glyceraldehyde-3-phosphate dehydrogenase (GAPC), a negative autophagic regulator, to induce autophagy in Nicotiana benthamiana. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: May 18, 2020

2020 journal article

Genetic and Agronomic Analysis of Tobacco Genotypes Exhibiting Reduced Nicotine Accumulation Due to Induced Mutations in Berberine Bridge Like (BBL) Genes

FRONTIERS IN PLANT SCIENCE, 11.

By: R. Lewis n, K. Drake-Stowe n, C. Heim n, T. Steede n, W. Smith n & R. Dewey n

author keywords: tobacco; Nicotiana tabacum; nicotine; alkaloids; gene editing; regulation
TL;DR: Genetic methodologies for reducing nicotine accumulation in the tobacco plant (Nicotiana tabacum L.) are of interest because of potential future regulations that could mandate lowering of this alkaloid in conventional cigarettes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: May 18, 2020

2020 article

My Mother's Story: Tick Borne Ehrlichiosis and a Life Well-Lived

Breitschwerdt, E. B., & Maggi, R. G. (2020, May 1). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 20, pp. 319–324.

By: E. Breitschwerdt n & R. Maggi n

author keywords: Ehrlichia; Bartonella; dementia; one health; non-Hodgkin's lymphoma
MeSH headings : Aged, 80 and over; Animals; Anti-Bacterial Agents / therapeutic use; Doxycycline / therapeutic use; Ehrlichia; Ehrlichiosis / diagnosis; Ehrlichiosis / drug therapy; Ehrlichiosis / epidemiology; Ehrlichiosis / pathology; Female; Humans; Maryland / epidemiology; Tick Bites; Ticks
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 18, 2020

2020 journal article

Bartonella rochalimae, a newly recognized pathogen in dogs

Journal of Veterinary Internal Medicine.

author keywords: emerging; endocarditis; infection; polymerase chain reaction; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / veterinary; Female; Lameness, Animal; Male; Polymerase Chain Reaction / veterinary; Retrospective Studies; Seizures / veterinary; United States
TL;DR: A spectrum of clinical presentations accompanied by mild hematological abnormalities in B rochalimae‐infected dogs from the United States is documented to provide support for an association between B rochardimae and IE and provides documentation of dogs infected with B ro Chalimae with other clinical diagnoses. (via Semantic Scholar)
Source: ORCID
Added: May 17, 2020

2020 journal article

Genetic Basis of Increased Lifespan and Postponed Senescence in Drosophila melanogaster

G3-GENES GENOMES GENETICS, 10(3), 1087–1098.

By: G. Parker n, N. Kohn, A. Spirina, A. McMillen, W. Huang* & T. Mackay n

author keywords: Laboratory evolution; candidate genes; RNAi
MeSH headings : Aging / genetics; Animals; Drosophila melanogaster / genetics; Female; Gene Expression; Genes, Insect; Longevity / genetics; Male; Ovary / metabolism; RNA Interference; Reproduction / genetics
TL;DR: Identifying evolutionarily conserved genes affecting increased lifespan and delayed reproductive senescence is the first step toward understanding the evolutionary forces that maintain segregating variation at these loci in nature and may provide potential targets for therapeutic intervention to delay senescences while increasing lifespan. (via Semantic Scholar)
Source: Web Of Science
Added: May 8, 2020

2020 journal article

Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs

JOURNAL OF CLINICAL MICROBIOLOGY, 58(4).

By: P. Neupane n, S. Sevala n, N. Balakrishnan*, H. Marr n, J. Wilson n, R. Maggi n, A. Birkenheuer n, M. Lappin*, B. Chomel*, E. Breitschwerdt n

author keywords: serology; zoonosis; vector borne; Western blotting; antigen; Bartonella henselae
MeSH headings : Animals; Antibodies, Bacterial; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae; Blotting, Western; Dog Diseases / diagnosis; Dogs; Serologic Tests
TL;DR: This study characterized WB immunodominant proteins that could be used to confirm a serodiagnosis of canine bartonelloses using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell proteins, and found a strong but variable recognition of these proteins among 81% of group II dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2020 journal article

Context-dependent genetic architecture of Drosophila life span

PLOS BIOLOGY, 18(3).

By: W. Huang n, T. Campbell n, M. Carbone n, W. Jones n, D. Unselt n, R. Anholt n, T. Mackay n

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Gene-Environment Interaction; Genetic Variation; Genome-Wide Association Study; Longevity / genetics; Male; RNA Interference; Temperature
TL;DR: The results implicate novel candidate genes affecting life span and suggest that variation for life span may be maintained by variable allelic effects in heterogeneous environments. (via Semantic Scholar)
Source: Web Of Science
Added: April 20, 2020

2020 journal article

Gene expression networks in the Drosophila Genetic Reference Panel

GENOME RESEARCH, 30(3), 485–496.

By: L. Everett n, W. Huang n, S. Zhou n, M. Carbone n, R. Lyman n, G. Arya n, M. Geisz n, J. Ma* ...

MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Drosophila melanogaster / microbiology; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Variation; High-Throughput Nucleotide Sequencing; Male; Microbiota / genetics; Quantitative Trait Loci; Sequence Analysis, RNA
TL;DR: This study performed deep RNA sequencing of 200 Drosophila Genetic Reference Panel inbred lines with complete genome sequences and mapped expression quantitative trait loci for annotated genes, novel transcribed regions, transposable elements and microbial species, providing new insights regarding the role of natural genetic variation in regulating gene expression. (via Semantic Scholar)
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Systems genetics of the Drosophila metabolome

GENOME RESEARCH, 30(3), 392–405.

By: S. Zhou n, F. Morgante n, M. Geisz n, J. Ma*, R. Anholt n & T. Mackay n

MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Female; Genetic Association Studies; Genetic Variation; Male; Metabolome / genetics; Phenotype; Quantitative Trait Loci
TL;DR: This work identified sex-specific modules of genetically correlated metabolites and constructed networks that integrate DNA sequence variation and variation in gene expression with variation in metabolites and organismal traits, including starvation stress resistance and male aggression. (via Semantic Scholar)
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Modeling buffer capacity and pH in acid and acidified foods

JOURNAL OF FOOD SCIENCE, 85(4), 918–925.

By: R. Price*, M. Longtin n, S. Conley-Payton*, J. Osborne n, S. Johanningsmeier*, D. Bitzer n, F. Breidt*

author keywords: acid; base; acid foods; acidified foods; buffer capacity; buffer model; pH
MeSH headings : Acids / analysis; Algorithms; Buffers; Chromatography, High Pressure Liquid; Food Analysis; Food Safety; Hydrogen-Ion Concentration; Models, Biological; Salts / analysis
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Detection of Phytophthora infestans by Loop-Mediated Isothermal Amplification, Real-Time LAMP, and Droplet Digital PCR

PLANT DISEASE, 104(3), 708–716.

By: J. Ristaino n, A. Saville n, R. Paul n, D. Cooper* & Q. Wei n

author keywords: oomycetes; pathogen detection; Phytophthora infestans; vegetables
MeSH headings : Solanum lycopersicum; Nucleic Acid Amplification Techniques; Phytophthora infestans; Polymerase Chain Reaction; Solanum tuberosum
TL;DR: The loop-mediated isothermal amplification (LAMP) assay was specific for P. infestans on potato and tomato and did not amplify other potato- or tomato-infecting Phytophthora species or other fungal and bacterial pathogens that infect potato and Tomato. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 6, 2020

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