Works Published in 2015
Displaying works 61 - 80 of 92 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes
CELL DEATH & DISEASE, 6.
MeSH headings : Animals; Apoptosis / genetics; Apoptosis / radiation effects; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cell Line; Cell Proliferation / genetics; Cell Proliferation / radiation effects; DNA Damage / genetics; DNA Damage / radiation effects; Gene Expression Regulation / radiation effects; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; Keratinocytes / radiation effects; Mice; RNA, Long Noncoding / biosynthesis; RNA, Long Noncoding / genetics; Skin / metabolism; Skin / pathology; Skin / radiation effects; Skin Neoplasms / genetics; Skin Neoplasms / pathology; Tumor Suppressor Protein p53 / genetics; Ultraviolet Rays
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster
SCIENTIFIC REPORTS, 5.
MeSH headings : Acclimatization / genetics; Animals; Cell Plasticity / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Ecosystem; Gene-Environment Interaction; Genetic Fitness / genetics; Quantitative Trait Loci / genetics
TL;DR:
This work quantified genetic variation for micro-environmental plasticity for three quantitative traits in the inbred, sequenced lines of the Drosophila melanogaster Genetic Reference Panel and identified several candidate genes associated with micro-Environmental plasticity of startle response, including Drosophile Hsp90.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Extending the Short and Long Wavelength Limits of Bacteriochlorin Near-Infrared Absorption via Dioxo- and Bisimide-Functionalization
JOURNAL OF PHYSICAL CHEMISTRY B, 119(12), 4382–4395.
MeSH headings : Carbon-13 Magnetic Resonance Spectroscopy; Molecular Structure; Photochemical Processes; Porphyrins / chemical synthesis; Porphyrins / chemistry; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Near-Infrared / methods
TL;DR:
Six new bacteriochlorins expanding the range of the strong near-infrared absorption (Qy band) to both shorter and longer wavelengths (∼690 to ∼900 nm) have been synthesized and characterized and have excited-state lifetimes that are sufficiently long for use in molecular-based systems for photochemical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 review
De Novo Synthesis of Gem-Dialkyl Chlorophyll Analogues for Probing and Emulating Our Green World
[Review of ]. CHEMICAL REVIEWS, 115(13), 6534–6620.
MeSH headings : Chlorophyll / chemical synthesis; Chlorophyll / chemistry; Molecular Structure; Porphyrins / chemical synthesis; Porphyrins / chemistry
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Synthetic bacteriochlorins bearing polar motifs (carboxylate, phosphonate, ammonium and a short PEG). Water-solubilization, bioconjugation, and photophysical properties
NEW JOURNAL OF CHEMISTRY, 39(7), 5694–5714.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Serological and molecular analysis of feline vector-borne anaplasmosis and ehrlichiosis using species-specific peptides and PCR
Parasites & Vectors, 8(1), 320.
author keywords: Anaplasma; Borrelia; Ehrlichia; Cats; Vector-borne pathogens
MeSH headings : Anaplasma / genetics; Anaplasma / immunology; Anaplasma / isolation & purification; Anaplasmosis / blood; Anaplasmosis / diagnosis; Anaplasmosis / microbiology; Animals; Antibodies, Bacterial / blood; Cat Diseases / blood; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cats; Ehrlichia / genetics; Ehrlichia / immunology; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Male; Peptides / genetics; Polymerase Chain Reaction; Prospective Studies; Species Specificity
TL;DR:
This study provides the first evidence for E.chaffeensis and E.ewingii infection in naturally-exposed cats in North America and supports the need for regional, serological and molecular FVBP prevalence studies, and the need to further optimize serodiagnostic and PCR testing for cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2015 journal article
Phosphorylation is an on/off switch for 5-hydroxyconiferaldehyde O-methyltransferase activity in poplar monolignol biosynthesis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8481–8486.
author keywords: AldOMT; COMT; lignin; phosphoproteomics; phosphoregulation
MeSH headings : Acrolein / analogs & derivatives; Acrolein / metabolism; Amino Acid Sequence; Binding Sites / genetics; Biocatalysis; Catechols / metabolism; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Isoenzymes / genetics; Isoenzymes / metabolism; Lignin / biosynthesis; Methyltransferases / genetics; Methyltransferases / metabolism; Microscopy, Confocal; Molecular Sequence Data; Mutation; Phosphoproteins / metabolism; Phosphorylation; Plant Proteins / genetics; Plant Proteins / metabolism; Populus / enzymology; Populus / genetics; Populus / metabolism; Proteomics / methods; Protoplasts / enzymology; Protoplasts / metabolism; Sequence Homology, Amino Acid; Tandem Mass Spectrometry
TL;DR:
It is shown that reversible monophosphorylation at Ser123 or Ser125 acts as an on/off switch for the activity of 5-hydroxyconiferaldehyde O-methyltransferase 2 (PtrAldOMT2), an enzyme central to monolignol biosynthesis for lignification in stem-differentiating xylem of Populus trichocarpa.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Near-infrared tunable bacteriochlorins equipped for bioorthogonal labeling
NEW JOURNAL OF CHEMISTRY, 39(6), 4534–4550.
TL;DR:
Nine lipophilic, wavelength-tunable bacteriochlorins (seven free base; two zinc chelates) have been prepared that bear a single bioconjugatable group, fulfilling two key molecular design criteria for use of NIR-active chromophores in a variety of photochemical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Modeling Climate Change Effects on the Height Growth of Loblolly Pine
FOREST SCIENCE, 61(4), 703–715.
author keywords: Pinus taeda; provenance test; statistical model; universal response function; climate change
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Comparison of Suspended Branch and Direct Infestation Techniques for Artificially Infesting Hemlock Seedlings with the Hemlock Woolly Adelgid for Resistance Screening
FORESTS, 6(6), 2066–2081.
author keywords: adelges tsugae; tsuga canadensis; tsuga caroliniana; tsuga heterophylla; artificial infestation
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
BRAF Mutations in Canine Cancers
PLOS ONE, 10(6).
MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Dogs; Exons / genetics; Female; Genetic Predisposition to Disease; Humans; Male; Molecular Sequence Data; Mutation / genetics; Neoplasms / genetics; Neoplasms / veterinary; Proto-Oncogene Proteins B-raf / chemistry; Proto-Oncogene Proteins B-raf / genetics; Sequence Analysis, DNA
TL;DR:
The evolutional conservation of the BRAF V600E mutation highlights the importance of MAPK pathway activation in neoplasia and may offer opportunity for molecular diagnostics and targeted therapeutics for dogs bearing BRAF-mutated cancers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 review
The Top 10 oomycete pathogens in molecular plant pathology
[Review of ]. Molecular Plant Pathology, 16(4), 413–434.
Source: NC State University Libraries
Added: August 6, 2018
2015 article
Peto's paradox and the promise of comparative oncology
Nunney, L., Maley, C. C., Breen, M., Hochberg, M. E., & Schiffman, J. D. (2015, July 19). PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol. 370.
author keywords: Peto's paradox; comparative oncology; evolution; life-history theory; cancer; modelling
MeSH headings : Animals; Biological Evolution; Body Size; Cocarcinogenesis; Female; Humans; Longevity; Male; Mammals; Models, Biological; Neoplasms / etiology
TL;DR:
The history of the field is reviewed and how the contributions use empirical, comparative and theoretical approaches to address the processes and patterns associated with ‘Peto's paradox’, the lack of a statistical relationship of cancer incidence with body size and longevity is outlined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Hydrophilic bioconjugatable trans-AB-porphyrins and peptide conjugates
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 19(5), 663–678.
author keywords: water-soluble; manganese; dipyrromethane; molecular design; facial encumbrance
TL;DR:
Porphyrins bearing a single bioconjugatable group and a single water-solubilization motif in a trans-AB-architecture provide a compact design of value for studies in diverse disciplines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Concurrent Bartonella henselae infection in a dog with panniculitis and owner with ulcerated nodular skin lesions
VETERINARY DERMATOLOGY, 26(1), 60-+.
MeSH headings : Aged; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / transmission; Angiomatosis, Bacillary / veterinary; Animals; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / transmission; Dogs; Female; Humans; Male; Skin / pathology; Skin Ulcer / microbiology; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / pathology
TL;DR:
B Bartonella henselae is an emerging zoonotic pathogen that induces granulomatous inflammatory lesions in various tissues of animals, including humans, and is concluded that this bacterium had a contributory or causative role in the development of the dermatological lesions in the dog and owner.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 review
Comparative oncology: what dogs and other species can teach us about humans with cancer
author keywords: comparative oncology; genomics; genetics; cancer; canine; human
MeSH headings : Animals; Breeding; Disease Models, Animal; Dog Diseases / etiology; Dogs; Female; Genome-Wide Association Study / veterinary; Genomics; Germ-Line Mutation; Humans; Male; Neoplasms / etiology; Neoplasms / veterinary; Risk Factors; Species Specificity; Translational Research, Biomedical
TL;DR:
This review begins with the genetic origins of canines and their advantage in cancer research, and next focuses on recent findings in comparative oncology related to inherited, or genetic, risk for tumour development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Bartonella clarridgeiae Bacteremia Detected in an Asymptomatic Blood Donor
JOURNAL OF CLINICAL MICROBIOLOGY, 53(1), 352–356.
MeSH headings : Adult; Bacteriological Techniques / methods; Bartonella / genetics; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Blood Donors; Humans; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR:
It is reported for the first time an asymptomatic human blood donor infected with B. clarridgeiae, as documented by enrichment blood culture, PCR, and DNA sequencing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
An autophosphorylation site database for leucine-rich repeat receptor-like kinases in Arabidopsis thaliana
PLANT JOURNAL, 82(6), 1042–1060.
author keywords: receptor kinase; phosphorylation; Arabidopsis thaliana; mass spectrometry; motif analysis
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Cytoplasm / metabolism; Databases, Factual; Escherichia coli / genetics; Molecular Sequence Data; Phosphorylation; Protein Kinases / genetics; Protein Kinases / metabolism; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Protein Structure, Tertiary
TL;DR:
This study employed high-throughput cloning and a variety of mass spectrometry approaches to generate an autophosphorylation site database representative of more than 30% of the approximately 223 LRR RLKs in Arabidopsis thaliana, and used this database to analyze trends in the localization of phosphorylation sites across cytoplasmic kinase subdomains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
A fast EM algorithm for fitting joint models of a binary response and multiple longitudinal covariates subject to detection limits
COMPUTATIONAL STATISTICS & DATA ANALYSIS, 85, 37–53.
author keywords: Detection limit; EM algorithm; Joint model; Logistic regression; Multiple longitudinal covariates; Normal approximation
TL;DR:
A fast, approximate EM algorithm is developed that reduces the dimension of integration in the E-step of the algorithm to one, regardless of the number of random effects in the joint model, and is applied to analyze the GenIMS data set.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Polarity-tunable and wavelength-tunable bacteriochlorins bearing a single carboxylic acid or NHS ester. Use in a protein bioconjugation model system
NEW JOURNAL OF CHEMISTRY, 39(1), 403–419.
TL;DR:
The results show facile access to a collection of useful bacteriochlorins for NIR spectroscopic studies, along with a pigment–protein system that serves the dual purposes of a convenient testbed for evaluating protein bioconjugation processes as well as a nanosized architecture for use in photochemical studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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