Genomic Sciences

Works Published in 2001

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Displaying works 121 - 140 of 155 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2001 journal article

The role of cell differentiation state and HMG-I/Y in the expression of transgenes flanked by matrix attachment regions

TRANSGENIC RESEARCH, 10(5), 465–470.

By: R. Ascenzi n, J. Ingram  n, M. Massel n, W. Thompson n , S. Spiker n & A. Weissinger n

author keywords: cell differentiation and proliferation; chromatin; matrix; scaffold attachment region (MAR/SAR); plant high mobility group-I/Y protein (HMG-I/Y); transgene expression; tobacco
MeSH headings : Cell Differentiation; Cells, Cultured; Gene Expression; HMGA1a Protein / genetics; HMGA1a Protein / metabolism; Plants, Genetically Modified; Tobacco / cytology; Tobacco / genetics
TL;DR: It appears that tobacco nuclear matrix attachment region function is not enhanced simply because cells in culture divide rapidly and are not differentiated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2001 journal article

Synthesis and excited-state photodynamics of perylene-porphyrindyads. Part 3, Effects of perylene, linker, and connectivity on ultrafast energy transfer

Journal of Materials Chemistry, 11(10), 2420–2430.

By: S. Yang*, R. Lammi*, S. Prathapan n, M. Miller n, J. Seth*, J. Diers *, D. Bocian *, J. Lindsey n , D. Holten *

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 patent

Method of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart  & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Linear mixed models with flexible distributions of random effects for longitudinal data

BIOMETRICS, 57(3), 795–802.

By: D. Zhang n & M. Davidian n 

author keywords: longitudinal data; multimodality; random effects; seminonparametric density; semiparametric mixed effects model; skewness
MeSH headings : Biometry; Cholesterol / blood; Data Interpretation, Statistical; Humans; Likelihood Functions; Linear Models; Longitudinal Studies
TL;DR: It is demonstrated that standard information criteria may be used to choose the tuning parameter and detect departures from normality, and the approach is illustrated via simulation and using longitudinal data from the Framingham study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Infection of Fetal Feline Brain Cells in Culture with Bartonella henselae

Infection and Immunity, 69(1), 564–569.

By: K. Munana n , S. Vitek n, B. Hegarty n, D. Kordick n & E. Breitschwerdt n 

MeSH headings : Animals; Astrocytes / microbiology; Bartonella henselae / physiology; Brain / cytology; Brain / microbiology; Brain Diseases / etiology; Cats; Cells, Cultured; DNA, Bacterial / analysis; Female; Fetus / microbiology; Microglia / microbiology; Microscopy, Electron; Pregnancy
TL;DR: A role for microglia in the pathogenesis of B. henselae-associated neurological disease is suggested, and evidence of infection was seen in Bartonella-inoculated astrocyte cultures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2001 patent

High-density non-volatile memory devices incorporating sandwich coordination compounds

Washington, DC: U.S. Patent and Trademark Office.

By: J. Lindsey 

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Generation of Intron-Containing, ER-Localized, Soluble-Modified Green Fluorescent Protein Genes for use in Plant Transformation

Plant Molecular Biology Reporter, 19(1), 13–26.

By: S. Mankin n & W. Thompson n 

TL;DR: Transient expression of theerGFPINTanderGFP genes is comparable in tobacco and maize suspension culture protoplasts, indicating that the PIV2 intron is spliced effectively in both monocotyledonous and dicotylingonous plant species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 journal article

Formation of antibiotic, biodegradable polymers by processing with Irgasan DP300R (Triclosan) and its inclusion compound with beta-cyclodextrin

Journal of Applied Polymer Science, 82(2), 300–309.

By: J. Lu n, M. Hill n, M. Hood n, D. Greeson n, J. Horton n, P. Orndorff n, A. Herndon n, A. Tonelli n

UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Calpain inhibition protects against virus-induced apoptotic myocardial injury

JOURNAL OF VIROLOGY, 75(1), 351–361.

By: R. DeBiasi *, C. Edelstein *, B. Sherry n & K. Tyler  n

MeSH headings : Animals; Apoptosis; Calpain / antagonists & inhibitors; Calpain / biosynthesis; Caspase Inhibitors; Creatine Kinase / blood; Cysteine Proteinase Inhibitors / therapeutic use; Dipeptides / therapeutic use; Mice; Myocarditis / prevention & control; Reoviridae Infections / complications; Reoviridae Infections / drug therapy; Reoviridae Infections / enzymology
TL;DR: It is demonstrated that myocardial injury results from apoptosis, the first evidence for the importance of a calpain-associated pathway of apoptotic cell death in viral disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Overwintering of Frankliniella fusca (Thysanoptera : Thripidae) on winter annual weeds infected with Tomato spotted wilt virus and patterns of virus movement between susceptible weed hosts

PHYTOPATHOLOGY, 91(9), 891–899.

By: R. Groves*, J. Walgenbach*, J. Moyer* & G. Kennedy* 

author keywords: F. occidentalis
TL;DR: Overwintering of tobacco thrips, Frankliniella fusca, was investigated on common winter annual host plants infected with Tomato spotted wilt virus (TSWV), suggesting that overwintering inoculum levels in an area can increase rapidly during the spring in susceptible weed hosts prior to planting of susceptible crops. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Overcoming host- and pathogen-mediated resistance in tomato and tobacco maps to the M RNA of Tomato spotted wilt virus

MOLECULAR PLANT-MICROBE INTERACTIONS, 14(2), 242–249.

By: K. Hoffmann, W. Qiu & J. Moyer*

MeSH headings : Bunyaviridae / genetics; Bunyaviridae / pathogenicity; Cloning, Molecular; Solanum lycopersicum / genetics; Solanum lycopersicum / virology; Phenotype; Plants, Toxic; RNA, Viral / genetics; Tobacco / genetics; Tobacco / virology
TL;DR: A viral genetic system was used to map the determinants of the ability of Tomato spotted wilt virus (TSWV) to overcome the R gene (Sw-5) in tomato and the resistance conferred by the nucleocapsid gene of TSWV (N gene) in tobacco. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

The drosophila genes disconnected and disco-related are redundant with respect to larval head development and accumulation of mRNAs from deformed target genes

Genetics, 157(1), 225–236.

By: J. Mahaffey, C. Griswold & Q. Cao

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Joint linkage and linkage disequilibrium mapping in natural populations

Genetics, 157(2), 899–909.

By: R. Wu & Z. Zeng

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Exposure to low pH is not required for penetration of mosquito cells by Sindbis virus

JOURNAL OF VIROLOGY, 75(4), 2010–2013.

By: R. Hernandez n, T. Luo  n & D. Brown n

MeSH headings : Aedes / virology; Ammonium Chloride / pharmacology; Animals; Cells, Cultured; Chloroquine / pharmacology; Hydrogen-Ion Concentration; Sindbis Virus / drug effects; Sindbis Virus / physiology; Virus Replication / drug effects
TL;DR: The results suggest that while these two drugs raise the pH of endosomes, they do not block insect cell penetration, and support previous results suggesting that exposure to an acid environment within the cell may not be an obligatory step in the process of infection of cells by alphaviruses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Dual interaction of a geminivirus replication accessory factor with a viral replication protein and a plant cell cycle regulator

VIROLOGY, 279(2), 570–576.

By: S. Settlage n, A. Miller n, W. Gruissem * & L. Hanley-Bowdoin n 

MeSH headings : Cell Cycle; Geminiviridae / physiology; Plant Proteins / metabolism; Protein Binding; Retinoblastoma Protein / metabolism; Viral Proteins / metabolism; Virus Replication
TL;DR: Experiments reported here established that AL3 also interacts with a plant homolog of the mammalian tumor suppressor protein, retinoblastoma (pRb), and analysis of truncated AL3 proteins indicated that pRb and AL1 bind to similar regions of AL3, whereas AL3 oligomerization is dependent on a different region of the protein. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2001 journal article

Immunodiagnosis of Ehrlichia canis Infection with Recombinant Proteins

Journal of Clinical Microbiology, 39(1), 315–322.

By: J. McBride *, R. Corstvet*, E. Breitschwerdt n  & D. Walker *

MeSH headings : Amino Acid Sequence; Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / chemistry; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Base Sequence; Blotting, Southern; Blotting, Western / methods; Cloning, Molecular; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Fluorescent Antibody Technique, Indirect / methods; Molecular Sequence Data; Recombinant Proteins / immunology; Sequence Analysis, DNA
TL;DR: The results of this study demonstrate that the rP43 and rP28 are sensitive and reliable serodiagnostic antigens for E. canis infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2001 journal article

Coinfection with Three Ehrlichia Species in Dogs from Thailand and Venezuela with Emphasis on Consideration of 16S Ribosomal DNA Secondary Structure

Journal of Clinical Microbiology, 39(1), 90–93.

By: J. Suksawat n, C. Pitulle n, C. Arraga-Alvarado*, K. Madrigal*, S. Hancock n & E. Breitschwerdt n 

MeSH headings : Animals; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Dog Diseases / microbiology; Dogs; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Species Specificity; Thailand; Venezuela
TL;DR: These results provide the first molecular documentation for the presence of E. platys 16S ribosomal DNA (rDNA) sequences reported from these two geographically divergent countries, and a phylogenetic analysis of the rRNA, incorporating the consideration of secondary structure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2001 journal article

Canine Rocky Mountain spotted fever: A retrospective study of 30 cases

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 37(1), 41–48.

By: A. Gasser n, A. Birkenheuer*  & E. Breitschwerdt* 

MeSH headings : Animals; Antibodies, Bacterial / blood; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dogs; Female; Male; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Rickettsia rickettsii / immunology; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / veterinary
TL;DR: Dogs with antibody titers of 1:1,024 or greater at the time of presentation had a higher incidence of more severe neurological dysfunction and cutaneous lesions and the survival rate following R. rickettsii infection was 100%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2001 book

Defending animal rights

Urbana, IL: University of Illinois Press.

By: T. Regan

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Semiparametric nonlinear mixed-effects models and their applications - Comment

Journal of the American Statistical Association, 96(456), 1288–1291.

By: X. Lin & D. Zhang

Source: NC State University Libraries
Added: August 6, 2018

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