Works Published in 2008

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Displaying works 141 - 158 of 158 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 journal article

Detection ofBartonella henselaein the Blood of 2 Adult Horses

Journal of Veterinary Internal Medicine, 22(2), 495–498.

By: S. Jones n, R. Maggi n, J. Shuler n, A. Alward n & E. Breitschwerdt n

author keywords: arthropathy; bartonellosis; purpura hemorrhagica; vasculitis
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteremia / drug therapy; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella Infections / blood; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Culture Media; DNA, Bacterial / blood; Female; Horse Diseases / blood; Horse Diseases / drug therapy; Horse Diseases / microbiology; Horses; Joint Diseases / drug therapy; Joint Diseases / microbiology; Joint Diseases / veterinary; Male; Polymerase Chain Reaction / veterinary; Vasculitis / drug therapy; Vasculitis / microbiology; Vasculitis / veterinary
TL;DR: The presence of Bartonella sp. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Protein folding: Are we there yet?

Archives of Biochemistry and Biophysics, 469(1), 1–3.

By: A. Clark

Source: NC State University Libraries
Added: August 6, 2018

2008 review

Minimizing frustration by folding in an aqueous environment

[Review of ]. Archives of Biochemistry and Biophysics, 469(1), 118–131.

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Effect of prior tillage and soil fertility amendments on dispersal of Phytophthora capsici and infection of pepper

EUROPEAN JOURNAL OF PLANT PATHOLOGY, 120(3), 273–287.

By: B. Liu n, M. Gumpertz n, S. Hu n & J. Ristaino n

Contributors: B. Liu n, M. Gumpertz n, S. Hu n & J. Ristaino n

author keywords: Phytophthora capsici; epidemiology; organic amendment; physical; chemical and biological parameters; disease spread
TL;DR: Both the previous tillage and fertility amendments affected the incidence of disease and dispersal of the pathogen and soil water content, soil porosity, humic matter content, and net mineralizable levels nitrogen were positively correlated and bulk density was negatively correlated with final incidence of Disease. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish

MECHANISMS OF DEVELOPMENT, 125(1-2), 167–181.

By: J. Lee*, R. Anholt n & G. Cole*

author keywords: olfactomedin-2; Pax6.1; zebrafish; islet-1; branchiomotor neurons; cranial neural crest; crestin
MeSH headings : Animals; Body Patterning; Central Nervous System / embryology; Extracellular Matrix Proteins / genetics; Extracellular Matrix Proteins / physiology; Eye Proteins / genetics; Gene Expression Regulation, Developmental; Glycoproteins / genetics; Glycoproteins / physiology; Homeodomain Proteins / genetics; PAX6 Transcription Factor; Paired Box Transcription Factors / genetics; RNA, Messenger / genetics; Repressor Proteins / genetics; Zebrafish / embryology
TL;DR: It is shown in zebrafish that olfactomedin-2 (OM2) is a developmentally regulated gene, and that knockdown of protein expression by morpholino antisense oligonucleotides leads to perturbations of nervous system development. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Detection of two Bartonella tamiae-like sequences in Amblyomma americanum (Acari : Ixodidae) using 16S-23S intergenic spacer region-specific primers

JOURNAL OF MEDICAL ENTOMOLOGY, 45(1), 176–179.

By: S. Billeter*, M. Miller, E. Breitschwerdt* & M. Levy*

author keywords: Bartonella; Amblyomma americanum; PCR
TL;DR: Based upon PCR and sequencing, an adult male and adult female tick harbored DNA sequences closely related to Bartonella tamiae (DQ395180) and potential transmission of Bart onella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

A compact water-soluble porphyrin bearing an iodoacetamido bioconjugatable site

ORGANIC & BIOMOLECULAR CHEMISTRY, 6(1), 187–194.

By: K. Borbas n, H. Kee*, D. Holten* & J. Lindsey n

MeSH headings : Amines / chemistry; Carboxylic Acids / chemistry; Magnetic Resonance Spectroscopy; Porphyrins / chemistry; Solubility; Spectrometry, Fluorescence; Water / chemistry
TL;DR: The synthesis of three new water-soluble trans-AB-porphyrins is reported, where each porphyrin bears a diphosphonate-terminated swallowtail group and an amino, acetamido, or iodoacetamido group, and the amine affords considerable versatility for functionalization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Independent origins of self-compatibility in Arabidopsis thaliana

MOLECULAR ECOLOGY, 17(2), 704–714.

author keywords: Arabidopsis thaliana; evolutionary genomics; molecular adaptation; reproductive strategies; self-incompatibility; S locus
MeSH headings : Amino Acid Sequence; Arabidopsis / classification; Arabidopsis / genetics; Arabidopsis Proteins / genetics; DNA, Plant / chemistry; DNA, Plant / genetics; Evolution, Molecular; Fertility / genetics; Genes, Plant; Genetics, Population; Genome, Plant; Genotype; Haplotypes; Molecular Sequence Data; Phylogeny; Pseudogenes; Sequence Analysis, DNA; Sequence Homology, Amino Acid
TL;DR: The results suggest that self‐compatibility, which appears to be fixed in this species, arose multiple times with different genetic bases, and indicates that a species‐specific trait is associated with parallel evolution at the molecular level. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Identification of motifs that are conserved in 12 Drosophila species and regulate midline glia vs. neuron expression

GENETICS, 178(2), 787–799.

By: P. Estes n, E. Fulkerson n & Y. Zhang n

MeSH headings : Animals; Conserved Sequence; DNA Primers; Drosophila / classification; Drosophila / genetics; Gene Expression Regulation; Genes, Reporter; Genetic Variation; Germ-Line Mutation; Nervous System Physiological Phenomena; Neuroglia / physiology; Neurons / physiology; Rats; Species Specificity
TL;DR: The results suggest short, highly conserved genomic sequences flanking Drosophila midline genes are indicative of functional regulatory regions and that small changes within these sequences can alter the expression pattern of a gene. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans - man and his best friend share more than companionship

CHROMOSOME RESEARCH, 16(1), 145–154.

author keywords: chromosome; comparative; dog; evolution; leukemia; lymphoma
MeSH headings : Animals; Chromosome Aberrations; Conserved Sequence; Cytogenetics; Dogs; Evolution, Molecular; Hematologic Neoplasms / genetics; Humans; Male; Synteny / genetics; Translocation, Genetic
TL;DR: It is suggested that humans and dogs share an ancestrally retained pathogenetic basis for cancer and that cytogenetic evaluation of canine tumors may provide greater insight into the biology of tumorigenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Characterization of a new family of protein kinases from Arabidopsis containing phosphoinositide 3/4-kinase and ubiquitin-like domains

BIOCHEMICAL JOURNAL, 409, 117–127.

author keywords: phosphoinositide kinase (PIK); phosphorylation; proteasome regulatory particle non-ATPase 10 subunit (proteasome RPN10 subunit); protein kinase; ubiquitin fusion degradation (UFD); ubiquitin-like domain (UBL domain)
MeSH headings : Adaptor Proteins, Signal Transducing / chemistry; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / metabolism; Catalysis; Class Ia Phosphatidylinositol 3-Kinase; Cloning, Molecular; DNA, Complementary / metabolism; Genetic Vectors; Humans; Phosphatidylinositol 3-Kinases / chemistry; Phosphatidylinositol 3-Kinases / metabolism; Phosphorylation; Phylogeny; Protein Kinases / chemistry; Protein Kinases / classification; Protein Structure, Tertiary; Recombinant Proteins / chemistry; Ubiquitin / chemistry; Ubiquitin / metabolism
TL;DR: In vitro analysis of AtPI4Kgamma4 indicates that it interacts directly with, and phosphorylates, two proteins involved in the ubiquitin-proteasome system, namely UFD1 (ubiquitin fusion degradation 1) and RPN10 (regulatory particle non-ATPase 10). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Prevalence of Ehrlichia canis, Anaplasma platys, Babesia canis vogeli, Hepatozoon canis, Bartonella vinsonii berkhoffii, and Rickettsia spp. in dogs from Grenada

VETERINARY PARASITOLOGY, 151(2-4), 279–285.

By: M. Yabsley*, J. McKibben*, C. Macpherson*, P. Cattan*, N. Cherry n, B. Hegarty n, E. Breitschwerdt n, T. O'Connor* ...

author keywords: Anaplasma; Babesia; Bartonella; dog; Ehrlichia; Hepatozoon; Rickettsia; Rhipicephalus sanguineus
MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / veterinary; Coccidia / isolation & purification; Coccidiosis / epidemiology; Coccidiosis / veterinary; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacterial Infections / diagnosis; Gram-Negative Bacterial Infections / epidemiology; Gram-Negative Bacterial Infections / veterinary; Grenada / epidemiology; Male; Polymorphism, Single Nucleotide; Prevalence; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 18S / genetics; Rhipicephalus sanguineus / microbiology; Rhipicephalus sanguineus / parasitology; Tick-Borne Diseases / diagnosis; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary
TL;DR: Results of this study indicate that dogs from Grenada are infected with multipletick-borne pathogens; therefore, tick-borne diseases should be included as differentials for dogs exhibiting thrombocytopenia, leukopenia, fever, or lethargy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Infusion of dye molecules into Red clover necrotic mosaic virus

CHEMICAL COMMUNICATIONS, (1), 88–90.

By: L. Loo n, R. Guenther n, S. Lommel n & S. Franzen n

MeSH headings : Capsid Proteins / chemistry; Capsid Proteins / metabolism; Coloring Agents / analysis; Coloring Agents / metabolism; Doxorubicin / metabolism; Microscopy, Electron, Transmission; Tombusviridae / chemistry; Tombusviridae / metabolism; Tombusviridae / ultrastructure
TL;DR: The Red clover necrotic mosaic virus capsid is utilized to package and release molecules through reversible depletion and re-addition of divalent cations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

In vivo depletion of CD4(+)CD25(+) regulatory T cells in cats

JOURNAL OF IMMUNOLOGICAL METHODS, 329(1-2), 81–91.

author keywords: regulatory T cell; FOXP3; feline immunodeficiency virus; monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal; Antibody Formation; CD4-Positive T-Lymphocytes / drug effects; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / drug effects; CD8-Positive T-Lymphocytes / immunology; Cats; Cell Proliferation; Cells, Cultured; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Gene Products, gag / pharmacology; Immunoglobulin G / blood; Immunologic Memory; Interleukin-2 Receptor alpha Subunit / immunology; Interleukin-2 Receptor alpha Subunit / metabolism; Lymphocyte Activation; Lymphocyte Depletion / methods; RNA, Messenger / metabolism; Recombinant Proteins / pharmacology; T-Lymphocytes, Regulatory / drug effects; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; Time Factors
TL;DR: It is concluded that despite alterations in CD25+ cell levels during depletion, the feline immune system remains functional and a model for the study of disease pathogenesis in the context of reduced numbers of immunosuppressive CD4+CD25+ Tregs throughout the f cat system is demonstrated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Expression of the bacteriophage T4 lysozyme gene in tall fescue confers resistance to gray leaf spot and brown patch diseases

TRANSGENIC RESEARCH, 17(1), 47–57.

author keywords: fungal resistance; Magnaporthe grisea; Rhizoctonia solani; T4 lysozyme; tall fescue
MeSH headings : Bacteriophage T4 / enzymology; Bacteriophage T4 / genetics; Cloning, Molecular; Festuca / enzymology; Festuca / genetics; Festuca / microbiology; Gene Expression; Genes, Viral; Genetic Vectors; Magnaporthe / pathogenicity; Muramidase / genetics; Plant Diseases / genetics; Plant Diseases / microbiology; Plants, Genetically Modified; Rhizobium / genetics; Rhizoctonia / pathogenicity
TL;DR: It is demonstrated that the bacteriophage T4 lysozyme gene confers resistance to both gray leaf spot and brown patch diseases in transgenic tall fescue plants, which may have wide applications in engineered fungal disease resistance in various crops. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Concurrent Hepatic Copper Toxicosis and Fanconi's Syndrome in a Dog

Journal of Veterinary Internal Medicine, 22(1), 219–222.

MeSH headings : Animals; Chelation Therapy / veterinary; Chemical and Drug Induced Liver Injury; Copper / metabolism; Dog Diseases / chemically induced; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Fanconi Syndrome / diagnosis; Fanconi Syndrome / therapy; Fanconi Syndrome / veterinary; Kidney / pathology; Liver / pathology; Liver Diseases / diagnosis; Liver Diseases / veterinary; Male; Metal Metabolism, Inborn Errors / diagnosis; Metal Metabolism, Inborn Errors / therapy; Metal Metabolism, Inborn Errors / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by a senescence-specific signaling pathway

PLANT MOLECULAR BIOLOGY, 66(4), 415–427.

By: M. Chakrabarti*, S. Bowen n, N. Coleman*, K. Meekins*, R. Dewey n & B. Siminszky*

author keywords: alkaloid; cytochrome P450; SAG; senescence-associated gene; stress; transcriptional regulation
MeSH headings : Aging / genetics; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Ethylenes / pharmacology; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucuronidase / genetics; Glucuronidase / metabolism; Plant Leaves / enzymology; Plant Leaves / growth & development; Plant Proteins / genetics; Plant Proteins / metabolism; Plants, Genetically Modified / enzymology; Promoter Regions, Genetic; Signal Transduction; Tobacco / drug effects; Tobacco / enzymology; Tobacco / genetics; Tobacco / growth & development
TL;DR: The results suggest that the expression of CYP 82E4 is senescence-specific in the leaves and the use of the CYP82E4 promoter could provide a valuable tool for regulating gene expression in the senescing leaves. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Bartonella DNA in the Blood and Lymph Nodes of Golden Retrievers with Lymphoma and in Healthy Controls

Journal of Veterinary Internal Medicine, 22(1), 89–95.

By: A. Duncan n, H. Marr n, A. Birkenheuer n, R. Maggi n, L. Williams n, M. Correa n, E. Breitschwerdt n

author keywords: bacteria; cancer; dog; tick; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / veterinary; Case-Control Studies; DNA, Bacterial / analysis; DNA, Bacterial / blood; Disease Vectors; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Female; Lymph Nodes / microbiology; Lymphoma / microbiology; Lymphoma / veterinary; Male; Models, Statistical; Polymerase Chain Reaction / veterinary; Risk Factors; Surveys and Questionnaires
TL;DR: Bartonella DNA can be detected in blood and lymph nodes; importantly, in this report, Bartonella was detected in the same proportion of clinically healthy dogs and dogs with lymphoma. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

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