Works Published in 2020
Displaying works 201 - 220 of 249 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice
NEUROTOXICOLOGY AND TERATOLOGY, 78.
Contributors: T. Jackson n, G. Bendfeldt n, K. Beam n, K. Rock n & S. Belcher n
author keywords: Cerebellum; Cortex; Holoprosencephaly; Hyperactivity; Medial prefrontal cortex; Medulloblastoma; Sex differences
MeSH headings : Animals; Cerebellum / anatomy & histology; Cerebellum / physiology; Cerebral Cortex / anatomy & histology; Cerebral Cortex / physiology; Female; Heterozygote; Hippocampus / anatomy & histology; Hippocampus / physiology; Mice, Knockout; Mutation; Patched-1 Receptor / genetics; Patched-1 Receptor / physiology; Sex Characteristics; Signal Transduction; Social Behavior
doi.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: April 14, 2020
2020 article
Gender differences in respiratory health outcomes among farming cohorts around the globe: findings from the AGRICOH consortium
JOURNAL OF AGROMEDICINE.
author keywords: Farmers; Respiratory Health; Gender; Farmworkers; Occupational Exposure
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agriculture; Female; Humans; Male; Occupational Exposure; Outcome Assessment, Health Care; Prevalence; Prospective Studies; Risk Factors; Sex Factors
TL;DR:
Assessment of respiratory disease prevalence among adults in 18 cohorts representing over 200,000 farmers, farm workers, and their spouses from six continents indicates that respiratory outcomes are common among farmers around the world despite differences in agricultural production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 7, 2020
2020 article
A three year study of metal levels in skin biopsies of whales in the Gulf of Mexico after the Deepwater Horizon oil crisis (vol 205, pg 15, 2018)
Wise, J. P., Jr., Wise, J. T. F., Wise, C. F., Wise, S. S., Gianios, C., Jr., Xie, H., … Wise, J. P., Sr. (2020, April). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, Vol. 230.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Timing of complementary feeding is associated with gut microbiota diversity and composition and short chain fatty acid concentrations over the first year of life
BMC MICROBIOLOGY, 20(1).
author keywords: Microbiome; Pediatrics; Weaning; Complementary feeding; Butyrate; Metabolites
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; DNA, Bacterial / genetics; DNA, Ribosomal / genetics; Fatty Acids, Volatile / analysis; Feces / chemistry; Feces / microbiology; Female; Gastrointestinal Microbiome; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Mothers; Phylogeny; Prospective Studies; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA / methods; Time Factors
TL;DR:
The findings are consistent with the hypothesis that early (vs. later) introduction to complementary foods is associated with altered gut microbiota composition and butyric acid concentrations measured in stool until at least 1 year of age.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 review
Mini-review: Epigenetic mechanisms that promote transgenerational actions of endocrine disrupting chemicals: Applications to behavioral neuroendocrinology
[Review of ]. HORMONES AND BEHAVIOR, 119.
author keywords: Chromatin; Transcription factors; CTCF; Transgenerational; Endocrine disrupting chemicals; Methylation; Bisphenol; PCB; Vinclozolin; Phthalates; Estrogen; Androgen
MeSH headings : Animals; Behavior / drug effects; Behavioral Research / methods; Behavioral Research / trends; Cohort Effect; DNA Methylation / drug effects; Endocrine Disruptors / pharmacology; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Epigenesis, Genetic / drug effects; Epigenesis, Genetic / physiology; Female; Humans; Male; Nervous System / drug effects; Nervous System / embryology; Nervous System / growth & development; Neuroendocrinology / methods; Neuroendocrinology / trends; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prenatal Exposure Delayed Effects / physiopathology; Reproduction / drug effects; Sex Differentiation / drug effects
TL;DR:
The literature on transgenerational actions of endocrine disrupting chemicals (EDCs) on brain and behavior and their underlying epigenetic mechanisms including: DNA methylation, histone modifications, and non-coding RNAs are examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Total Eclipse of the Zoo: Animal Behavior during a Total Solar Eclipse
Animals, 10(4), 587.
author keywords: weather; zoo; anxiety; light; captive
TL;DR:
These observations provide novel insight into the observed responses of a diverse vertebrate sample during a unique meteorological stimulus, insights that supplement the rare observations of behavior during this phenomenon for contextualizing future studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: April 2, 2020
2020 review
Beyond the looking glass: recent advances in understanding the impact of environmental exposures on neuropsychiatric disease
[Review of ]. NEUROPSYCHOPHARMACOLOGY, 45(7), 1086–1096.
MeSH headings : Environmental Exposure / adverse effects; Humans; Mental Disorders / etiology
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: March 30, 2020
2020 journal article
Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function
ARCHIVES OF TOXICOLOGY, 94(2), 469–484.
author keywords: Neurotoxicity; Screening; ToxCast
MeSH headings : Animals; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Databases, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical / methods; Machine Learning; Microelectrodes; Nerve Net / drug effects; Neural Networks, Computer; Neurons / drug effects; Neurotoxicity Syndromes / pathology; Rats, Long-Evans; Toxicity Tests / methods
TL;DR:
It is demonstrated that multivariate MEA activity patterns can efficiently screen for diverse chemical activities relevant to neurotoxicity, and that response patterns may have predictive value related to chemical structural features.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID
Added: March 30, 2020
2020 journal article
Involvement of glutamate and serotonin transmitter systems in male sex determination in Daphnia pulex
JOURNAL OF INSECT PHYSIOLOGY, 121.
author keywords: Environmental sex determination; Endocrine cascade; Juvenile hormones; Zooplankton; Abiotic stimuli; N-methyl-D-aspartate receptor
MeSH headings : Animals; Daphnia / genetics; Daphnia / metabolism; Daphnia / physiology; Environment; Gene Expression; Glutamic Acid / genetics; Glutamic Acid / metabolism; Male; Neurotransmitter Agents / genetics; Neurotransmitter Agents / metabolism; Receptors, N-Methyl-D-Aspartate / agonists; Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors; Receptors, N-Methyl-D-Aspartate / metabolism; Seasons; Serotonin / genetics; Serotonin / metabolism; Sex Determination Processes / genetics; Sex Determination Processes / physiology; Signal Transduction
TL;DR:
Evidence is provided that glutamatergic and serotonergic systems function upstream of the endocrine regulation of male sex determination in early life stage daphnids.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID
Added: March 30, 2020
2020 journal article
Associations between attention deficit hyperactivity disorder symptoms and eating behaviors in early childhood
PEDIATRIC OBESITY, 15(7).
author keywords: ADHD; childhood; eating behaviors; latent change score; self-regulation
MeSH headings : Adolescent; Adult; Attention Deficit Disorder with Hyperactivity / psychology; Child; Child, Preschool; Cross-Sectional Studies; Feeding Behavior / psychology; Female; Humans; Hyperphagia / psychology; Male; Pediatric Obesity / etiology; Pediatric Obesity / prevention & control; Prospective Studies; Young Adult
TL;DR:
Attention‐deficit/hyperactivity disorder symptoms have been linked with eating behaviors and obesity adolescence and young adulthood, but little is known about whether these associations occur during early childhood and few studies have examined these associations prospectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 23, 2020
2020 journal article
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury
ELIFE, 9.
MeSH headings : Animals; Cells, Cultured; Humans; Inflammation / immunology; Inflammation / metabolism; Lung / immunology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Macrophages / immunology; Macrophages / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88 / genetics; Myeloid Differentiation Factor 88 / metabolism; Polymorphism, Single Nucleotide / genetics; Signal Transduction / genetics; Signal Transduction / immunology; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Toll-Like Receptor 5 / genetics; Toll-Like Receptor 5 / metabolism
TL;DR:
It is demonstrated that immune cells of human carriers of a dominant negative TLR5 allele have decreased inflammatory response to O3 exposure ex vivo and LPS exposure in vitro, and suggests an updated paradigm for TLR4/TLR5 signaling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 16, 2020
2020 journal article
Fungal and Bacterial Communities Exhibit Consistent Responses to Reversal of Soil Acidification and Phosphorus Limitation over Time
MICROORGANISMS, 8(1).
author keywords: bacteria; fungi; pH; community structure; 454 sequencing
TL;DR:
This study examined microbial communities in an ecosystem level manipulative experiment where pH and/or P availability were elevated in three separate forests in Northeastern Ohio and found significant effects of pH treatment and time on fungal and bacterial communities in soil, but found no interaction and only a weak interaction between pH elevation and time for bacterial communities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 16, 2020
2020 journal article
Aerobic biodegradation in freshwater and marine environments of textile microfibers generated in clothes laundering: Effects of cellulose and polyester-based microfibers on the microbiome
Marine Pollution Bulletin, 151, 110826.
author keywords: Biodegradability; Aquatic biodegradation; Cotton; Polyester; Rayon; Bacterial communities
MeSH headings : Biodegradation, Environmental; Cellulose; Clothing; Laundering; Microbiota; Polyesters; Textiles; Water Pollutants / analysis
TL;DR:
The bacterial diversity analyses in the different biodegradation inoculums show that there are distinct bacterial communities related to the assimilation and mineralization of complex carbohydrates that were promoted with the cellulosic MCC, cotton, and rayon samples different than the polyester sample.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: March 16, 2020
2020 journal article
Metal contamination of river otters in North Carolina
ENVIRONMENTAL MONITORING AND ASSESSMENT, 192(2).
MeSH headings : Animals; Environmental Monitoring; Mercury / analysis; Metals; North Carolina; Otters
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 16, 2020
2020 journal article
Gridlock and beltways: the genetic context of urban invasions
Oecologia.
author keywords: Synthesis; Population genetics; Landscape genetics; Invasive species; Urban ecosystems
MeSH headings : Biological Evolution; Cities; Ecology; Ecosystem; Genetic Variation; Introduced Species
TL;DR:
It is concluded that urban areas are not only points of entry for many invasive species, they also facilitate population establishment, are pools for genetic diversity, and provide corridors for further spread both within and out of cities.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: March 13, 2020
2020 journal article
Improving Cancer Drug Discovery by Studying Cancer across the Tree of Life
MOLECULAR BIOLOGY AND EVOLUTION, 37(1), 11–17.
author keywords: veterinary oncology; cross-species studies; cancer drug discovery; evolutionary biology
MeSH headings : Animals; Drug Discovery; Humans; Neoplasms / drug therapy; Neoplasms / veterinary
TL;DR:
Clinical trials in veterinary patients with cancer provide an opportunity to evaluate a novel therapeutic in a setting that recapitulates many of the key features of human cancers, including key genomic aberrations that underly tumor development, response and resistance to treatment, and the presence of comorbidities that can affect outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 10, 2020
2020 journal article
Elevated levels of per- and polyfluoroalkyl substances in Cape Fear River Striped Bass (Morone saxatilis) are associated with biomarkers of altered immune and liver function
ENVIRONMENT INTERNATIONAL, 136.
Contributors: T. Guillette n, J. McCord*, M. Guillette n, M. Polera n, K. Rachels*, C. Morgeson*, N. Kotlarz n , D. Knappe n
MeSH headings : Animals; Bass; Biomarkers; Fluorocarbons / toxicity; Liver; Rivers; Water Pollutants, Chemical / toxicity
TL;DR:
The elevated PFAS concentrations found in the Cape Fear River Striped Bass were associated with biomarkers of alterations in the liver and immune system, and correlations betweenPFAS concentrations and health-related serum biomarkers were evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 2, 2020
2020 journal article
Exploratory behaviour is associated with microhabitat and evolutionary radiation in Lake Malawi cichlids
ANIMAL BEHAVIOUR, 160, 121–134.
author keywords: behavioural integration; behavioural modularity; habitat preference; light-dark; novel stimuli; novel tank; open field; scototaxis; stress response; thigmotaxis
TL;DR:
This study investigates behavioural responses to novel environments, or exploratory behaviours, in a previously untested vertebrate system, Lake Malawi cichlid fishes, which comprises hundreds of phenotypically diverse species that have diverged in the past one million years.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 27, 2020
2020 journal article
The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis
JOURNAL OF MOLECULAR BIOLOGY, 432(2), 343–357.
author keywords: Biofilms; Bacillus subtilis; Transcriptional regulation; NMR solution structure
MeSH headings : Amino Acid Sequence / genetics; Bacillus subtilis / genetics; Bacillus subtilis / ultrastructure; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / ultrastructure; Biofilms / growth & development; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / genetics; DNA-Binding Proteins / ultrastructure; Gene Expression Regulation, Bacterial / genetics; Molecular Docking Simulation; Mutation / genetics; Protein Binding / genetics; Protein Conformation
TL;DR:
This work presents the first full-length structural model of tetrameric SinR using a hybrid approach combining high-resolution solution NMR, chemical crosslinking, mass spectrometry, and molecular docking, and provides an evidence-based mechanism that confirms how disruption of the SinR tetramer by SinI regulates gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 27, 2020
2020 review
Achieving CLARITY on bisphenol A, brain and behaviour
[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 32(1).
author keywords: amygdala; anxiety; EDC; endocrine disrupting chemical; hypothalamus; oxytocin
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Brain / drug effects; Endocrine Disruptors / toxicity; Female; Humans; Male; Neurons / drug effects; Phenols / toxicity; Pregnancy; Sex Differentiation / drug effects; United States; United States Food and Drug Administration
TL;DR:
Evidence of altered neuroendocrine development, including age‐ and sex‐specific expression of oestrogen receptor (ER)α and ERβ, and the abrogation of brain and behavioural sexual dimorphisms, supports the conclusion that developmental BPA exposure, even at doses below what regulatory agencies regard as “safe” for humans, contribute to brain and behaviour change.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: February 17, 2020
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