Works Published in 2005
Displaying works 21 - 40 of 133 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Lack of functional estrogen receptor β influences anxiety behavior and serotonin content in female mice
Physiology & Behavior, 84(1), 157–163.
author keywords: SSRI; menopause; estrogen receptor; depression; anxiety; serotonin
MeSH headings : Analysis of Variance; Animals; Anxiety / genetics; Anxiety / metabolism; Anxiety / physiopathology; Behavior, Animal; Biogenic Monoamines / metabolism; Brain Chemistry / drug effects; Brain Chemistry / genetics; Chromatography, High Pressure Liquid / methods; Estradiol / pharmacology; Estrogen Receptor beta / deficiency; Estrogen Receptor beta / genetics; Exploratory Behavior / drug effects; Female; Genotype; Maze Learning / drug effects; Mice; Mice, Knockout; Ovariectomy / methods; Serotonin / metabolism; Time Factors
TL;DR:
It is hypothesized that ERbeta is required during development to modulate the effects of estrogen on anxiety and catecholamine concentrations in female mouse brains in the absence of functional ERbeta.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Dopamine D5 receptor modulates male and female sexual behavior in mice
Psychopharmacology, 180(2), 206–214.
author keywords: sexual behavior; dopamine; conditioned place preference; drugs; motivation; knockout mice; reward; attention deficit hyperactivity disorder
MeSH headings : Animals; Apomorphine / pharmacology; Conditioning, Psychological; Estradiol / pharmacology; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Progesterone / pharmacology; Reward; Sexual Behavior, Animal
TL;DR:
The work suggests that the D5 receptor mediates dopamine’s action on sexual behavior in both sexes, perhaps via a reward pathway.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Pain predicts non-adherence to pap smear screening among middle-aged African American women
Preventive Medicine, 41(2), 439–445.
author keywords: cervix neoplasms; screening; pap tests; African Americans; middle-aged; barriers; pain
MeSH headings : Black or African American / statistics & numerical data; Aged; Cross-Sectional Studies; Female; Focus Groups; Humans; Logistic Models; Middle Aged; Pain / etiology; Papanicolaou Test; Patient Acceptance of Health Care; United States; Uterine Cervical Neoplasms / prevention & control; Vaginal Smears / adverse effects; Vaginal Smears / statistics & numerical data
TL;DR:
Data suggest that, among middle-aged African American women, future interventions addressing pain during a Pap test will likely increase acceptability of and adherence to cervical cancer screening.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Anthropometric Measurements and Epithelial Ovarian Cancer Risk in African–American and White women
Cancer Causes & Control, 16(8), 955–963.
author keywords: body height; body mass index; etiology; ovarian neoplasms
MeSH headings : Adult; Black or African American / classification; Aged; Anthropometry; Body Height; Body Mass Index; Case-Control Studies; Confounding Factors, Epidemiologic; Female; Humans; Middle Aged; North Carolina / ethnology; Odds Ratio; Ovarian Neoplasms / ethnology; Risk Factors; White People / classification
TL;DR:
The hypothesis that obesity is an important risk factor of ovarian cancer among African–Americans and Whites is supported and height may be a risk factor specific to African–American women is suggested.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion
Proceedings of the National Academy of Sciences, 102(9), 3342–3347.
Contributors: J. Schimenti *, J. Reynolds * & A. Planchart*
MeSH headings : Animals; Base Sequence; Chromosomes, Artificial, Bacterial; DNA; Haplotypes; Infertility, Male / genetics; Male; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins / genetics; Phosphoric Monoester Hydrolases / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
Results uncouple the proximal t haplotype sterility locus, S1, from TRD, demonstrating that S1 and the proximate distorter loci, D1, are not the same gene.
(via Semantic Scholar)
www.pnas.org (publisher PDF)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2005 journal article
Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?
Marine Pollution Bulletin, 51(8-12), 635–648.
MeSH headings : Animals; Animals, Genetically Modified / metabolism; Carcinogenicity Tests / methods; Ecology / methods; Endocrine Disruptors / metabolism; Environmental Pollutants / metabolism; Models, Animal; Oligonucleotide Array Sequence Analysis / methods; Toxicology / methods; Toxicology / trends
TL;DR:
Studies resolving mechanisms of toxicity are reviewed and ways to address biocomplexity, mixtures of contaminants, and the need to relate individual level responses to populations and communities are discussed.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Functional characterization of medaka CYP3A38 and CYP3A40: Kinetics and catalysis by expression in a recombinant baculovirus system
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 141(4), 338–348.
author keywords: medaka; CYP3A; baculovirus; cytochrome P450; kinetics; testosterone; BFC; metabolism
MeSH headings : Amino Acid Sequence; Animals; Baculoviridae / genetics; Catalysis; Cytochrome P-450 CYP3A / chemistry; Cytochrome P-450 CYP3A / metabolism; Kinetics; Molecular Sequence Data; Oryzias / metabolism; Oxazines / metabolism; Recombinant Proteins / metabolism; Testosterone / metabolism
TL;DR:
Describing the catalytic and kinetic activities of two medaka CYP3A paralogs with benzyloxyresorufin (BFC), a fluorescent 3A-selective substrate, and testosterone suggests that differences in kinetics and catalytic activities are a result of amino acid substitutions in SRS regions 1, 3 and 5 within the CYP1A38 and CYP2A40 protein sequence.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Differences in Dissolved Cadmium and Zinc Uptake among Stream Insects: Mechanistic Explanations
Environmental Science & Technology, 39(2), 498–504.
MeSH headings : Animals; Biological Availability; Cadmium / pharmacokinetics; Insecta; Kinetics; Solubility; Tissue Distribution; Water Pollutants / pharmacokinetics; Zinc / pharmacokinetics
TL;DR:
Comparing dissolved Cd and Zn uptake rates in several aquatic insect species demonstrated that species vary widely in these processes, suggesting that these metals are transported by similar mechanisms.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Susceptibility of Signal Transducer and Activator of Transcription-1-Deficient Mice to Pulmonary Fibrogenesis
The American Journal of Pathology, 167(5), 1221–1229.
MeSH headings : Animals; Bleomycin / toxicity; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen / analysis; Disease Models, Animal; Epidermal Growth Factor / pharmacology; Fibroblasts / pathology; Growth Inhibitors / pharmacology; Hydroxyproline / analysis; Interferon-gamma / pharmacology; Lung / drug effects; Lung / pathology; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3 / metabolism; Phosphorylation; Platelet-Derived Growth Factor / pharmacology; Pulmonary Fibrosis / genetics; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / physiopathology; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / physiology; STAT3 Transcription Factor / metabolism; Thymidine / metabolism
TL;DR:
The findings indicate that Stat1-/- mice are more susceptible to bleomycin-induced lung fibrosis than wild-type mice due to 1) enhanced fibroblast proliferation in response to growth factors (EGF and PDGF), 2) stimulation of fibro Blast growth by a Stat 1-independent IFN-gamma signaling pathway, and 3) increased activation of Stat3.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Male genital size reflects a tradeoff between attracting mates and avoiding predators in two live-bearing fish species
Proceedings of the National Academy of Sciences, 102(21), 7618–7623.
author keywords: fitness tradeoff; genital evolution; mate choice; natural selection; sexual selection
MeSH headings : Analysis of Variance; Animals; Bahamas; Body Weights and Measures; Cyprinodontiformes / anatomy & histology; Cyprinodontiformes / physiology; Food Chain; Genitalia, Male / anatomy & histology; Male; Selection, Genetic; Sex Factors; Sexual Behavior, Animal; Swimming / physiology; Texas
TL;DR:
Although postmating sexual selection is widely presumed to be the most important mechanism driving genital diversification, these findings suggest that alternative mechanisms, particularly for organisms that cannot retract their genitalia, may also prove important.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Crossref
Added: June 6, 2020
2005 journal article
A comparative study on androgen metabolism in three invertebrate species
General and Comparative Endocrinology, 143(3), 211–221.
author keywords: testosterone; androstenedione; metabolism; mollusc; Crustacean; echinoderm
MeSH headings : Amphipoda / physiology; Androstenedione / metabolism; Animals; Biotransformation; Echinodermata / physiology; Female; Male; Sex Characteristics; Snails / physiology; Testosterone / metabolism
TL;DR:
Results demonstrate the ubiquity of some androgen biotransformation processes in invertebrates and reveals interphyla differences in androgen metabolic pathways, and different sensitivity of these pathways to some xenobiotics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 8, 2020
2005 journal article
West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment
Virology, 342(1), 77–87.
author keywords: West Nile virus; interferon; TLR3; IRF3; innate immunity; double-stranded RNA
MeSH headings : Active Transport, Cell Nucleus; Cell Line; Dimerization; HeLa Cells; Humans; Immunity, Innate; Interferon Regulatory Factor-3 / chemistry; Interferon Regulatory Factor-3 / metabolism; Interferon-beta / biosynthesis; Interferon-beta / genetics; Poly I-C / pharmacology; RNA, Viral / genetics; Replicon; STAT1 Transcription Factor / metabolism; Signal Transduction; Transcription, Genetic / drug effects; Virus Replication; West Nile virus / genetics; West Nile virus / immunology; West Nile virus / pathogenicity; West Nile virus / physiology
TL;DR:
It is demonstrated that WNV replication in cultured cells interferes with both the response to IFN and synthesis of IFN-beta in response to dsRNA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 24, 2020
2005 journal article
Electrophysiological Properties of Neurons in the Basal Ganglia of the Domestic Chick: Conservation and Divergence in the Evolution of the Avian Basal Ganglia
Journal of Neurophysiology, 94(1), 454–467.
MeSH headings : Age Factors; Animals; Animals, Newborn; Basal Ganglia / cytology; Basal Ganglia / growth & development; Chickens; Choline O-Acetyltransferase / metabolism; Dose-Response Relationship, Radiation; Electric Stimulation / methods; Electrophysiology; Immunohistochemistry / methods; In Vitro Techniques; Lysine / analogs & derivatives; Lysine / metabolism; Membrane Potentials / drug effects; Membrane Potentials / physiology; Membrane Potentials / radiation effects; Neurons / classification; Neurons / physiology; Patch-Clamp Techniques / methods
TL;DR:
It is discovered that spiny neurons, the most common cell type in the striatum of all amniotes, possess a diverse set of physiological properties in chicks that distinguish them from both mammals and songbirds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2005 journal article
Seasonal-like plasticity of spontaneous firing rate in a songbird pre-motor nucleus
Journal of Neurobiology, 64(2), 181–191.
author keywords: androgen; estrogen; testosterone; electrophysiology; birdsong
MeSH headings : Action Potentials / drug effects; Action Potentials / physiology; Analysis of Variance; Animals; Brain / cytology; Brain / drug effects; Brain / physiology; Dihydrotestosterone / blood; Dihydrotestosterone / pharmacology; Drug Interactions; Estradiol / blood; Estradiol / pharmacology; In Vitro Techniques; Male; Neural Pathways / drug effects; Neural Pathways / physiology; Neuronal Plasticity / drug effects; Neuronal Plasticity / physiology; Neurons / drug effects; Neurons / physiology; Photoperiod; Seasons; Songbirds; Statistics as Topic; Testosterone / blood; Testosterone / pharmacology; Time Factors; Vocalization, Animal / drug effects; Vocalization, Animal / physiology
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2005 journal article
Differing Roles of Inhibition in Hierarchical Processing of Species-Specific Calls in Auditory Brainstem Nuclei
Journal of Neurophysiology, 94(6), 4019–4037.
MeSH headings : Acoustic Stimulation / methods; Action Potentials / drug effects; Action Potentials / physiology; Animals; Auditory Pathways / physiology; Bicuculline / pharmacology; Brain Stem / cytology; Brain Stem / physiology; Cell Count / methods; Chiroptera; Dose-Response Relationship, Radiation; Drug Interactions; Echolocation / drug effects; Echolocation / physiology; Electrodes; Functional Laterality; GABA Antagonists / pharmacology; Glycine Agents / pharmacology; Neural Inhibition / drug effects; Neural Inhibition / physiology; Neurons / classification; Neurons / drug effects; Neurons / physiology; Sound Localization; Species Specificity; Strychnine / pharmacology; gamma-Aminobutyric Acid / pharmacology
TL;DR:
It is shown that inhibition plays only limited roles in the DNLL and INLL but dominates in the IC, where the various patterns of inhibition sculpt a wide variety of emergent response properties from the backdrop of more expansive and far less specific excitatory innervation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2005 chapter
THE MOUSE IN BIOMEDICAL RESEARCH
In The Mouse in Animal Genetics and Breeding Research (pp. 319–340).
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2005 journal article
Masking in Waved‐2 Mice: EGF Receptor Control of Locomotion Questioned
Chronobiology International, 22(6), 963–974.
author keywords: circadian rhythm; epidermal growth factor; locomotion; masking; subparaventricular zone; waved-2; mutants
MeSH headings : Animals; Circadian Rhythm / genetics; DNA Primers; ErbB Receptors / genetics; Lighting; Mice; Mice, Mutant Strains; Motor Activity / physiology; Polymerase Chain Reaction
TL;DR:
Study of the responses to light over a large range in illumination levels, in a variety of tests, with pulses of light and with ultradian light‐dark cycles in Egfrwa2 mutant mice suggested that normal functioning of epidermal growth factor receptors was required, or even involved, in masking.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2005 journal article
A new Oviraptorosaur (Theropoda, Maniraptora) from the Late Cretaceous (Campanian) of Utah
Journal of Vertebrate Paleontology, 25(4), 897–904.
TL;DR:
The discovery of this new specimen from southern Utah greatly expands the known geographic distribution of these theropods, nearly doubling the previously documented range of North American oviraptorosaurs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 17, 2019
2005 journal article
A primitive therizinosauroid dinosaur from the Early Cretaceous of Utah
Nature, 435(7038), 84–87.
MeSH headings : Animals; Dinosaurs / anatomy & histology; Dinosaurs / classification; Fossils; History, Ancient; Phylogeny; Skeleton; Skull / anatomy & histology; Species Specificity; Tooth / anatomy & histology; Utah
TL;DR:
A new, primitive therizinosauroid is described from an extensive paucispecific bonebed at the base of the Cedar Mountain Formation of east-central Utah, indicating that this species documents the earliest known stage in the poorly understood transition from carnivory to herbivory within Therizinosauroidea.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 17, 2019
2005 journal article
RacGap50C Negatively Regulates Wingless Pathway Activity During Drosophila Embryonic Development
Genetics, 169(4), 2075–2086.
MeSH headings : Alleles; Animals; Armadillo Domain Proteins; Axin Protein; Body Patterning; Crosses, Genetic; Drosophila Proteins / biosynthesis; Drosophila Proteins / chemistry; Drosophila Proteins / metabolism; Epidermis / embryology; Epidermis / metabolism; GTPase-Activating Proteins / chemistry; GTPase-Activating Proteins / metabolism; GTPase-Activating Proteins / physiology; Gene Expression Regulation, Developmental; Green Fluorescent Proteins / metabolism; In Situ Hybridization; Mutation; Phenotype; Protein Binding; Proto-Oncogene Proteins / biosynthesis; RNA / metabolism; Repressor Proteins / genetics; Signal Transduction; Trans-Activators / biosynthesis; Transgenes; Wings, Animal / embryology; Wnt1 Protein
TL;DR:
Two mutant lines that modify wg-mediated epidermal patterning represent the first loss-of-function mutations in the RacGap50C gene, which suggests that the mutant embryos suffer from ectopic Wg pathway activation.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 16, 2019
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