Works Published in 2017
Displaying works 61 - 80 of 248 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Loss of Heterozygosity Drives Adaptation in Hybrid Yeast
Molecular Biology and Evolution, 34(7), 1596–1612.
author keywords: hybrid; adaptation; loss of heterozygosity; experimental evolution; Saccharomyces uvarum; Saccharomyces cerevisiae
MeSH headings : Adaptation, Physiological / genetics; Biological Evolution; Genome / genetics; Hybridization, Genetic / genetics; Loss of Heterozygosity / genetics; Saccharomyces / genetics; Saccharomyces cerevisiae / genetics
TL;DR:
This is an example where hybrid genome resolution is driven by positive selection on existing heterozygosity and demonstrates that even infrequent outcrossing may have lasting impacts on adaptation.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 12, 2019
2017 article
Identification of a novel interspecific hybrid yeast from a metagenomic spontaneously inoculated beer sample using Hi-C
Heil, C. S., Burton, J. N., Liachko, I., Friedrich, A., Hanson, N. A., Morris, C. L., … Dunham, M. J. (2017, June). (Vol. 6). Vol. 6.
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 12, 2019
2017 journal article
Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast
Genetics, 206(2), 1153–1167.
author keywords: flocculation; experimental evolution; yeast; chemostat; FLO1
MeSH headings : Cell Aggregation / genetics; DNA Transposable Elements / genetics; Directed Molecular Evolution; Flocculation; Genetics, Population; Mannose-Binding Lectins / genetics; Nuclear Proteins / genetics; Phenotype; Promoter Regions, Genetic; Repressor Proteins / genetics; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae Proteins / genetics; Sequence Deletion
TL;DR:
Evolving a flo1 deletion strain revealed that this single deletion reduces flocculation occurrences to 3%, and demonstrated the efficacy of using experimental evolution as a tool to identify and eliminate the primary adaptive routes for undesirable traits.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2017 article
A genetic basis for molecular asymmetry at vertebrate electrical synapses
Miller, A. C., Whitebirch, A. C., Shah, A. N., Marsden, K. C., Granato, M., O'Brien, J., & Moens, C. B. (2017, January). (Vol. 1). Vol. 1.
Source: ORCID
Added: September 12, 2019
2017 journal article
Endocrine Disruption of Vasopressin Systems and Related Behaviors
Frontiers in Endocrinology, 8.
author keywords: bisphenol; oxytocin; sex differences; EDC; genistein; soy; social; anxiety; estrogens
TL;DR:
Endocrine disrupting chemicals shown to alter pathways and behaviors coordinated by AVP and/or OT include the plastics component bisphenol A (BPA), the soy phytoestrogen genistein (GEN), and various flame retardants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Crossref, ORCID
Added: August 17, 2019
2017 journal article
Chemical Contributions to Neurodevelopmental Disorders
Policy Insights from the Behavioral and Brain Sciences, 4(2), 123–130.
Ed(s): S. Fiske
Sources: Crossref, ORCID
Added: August 17, 2019
2017 article
Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish
The Rights and Wrongs of Zebrafish: Behavioral Phenotyping of Zebrafish, pp. 259–272.
Contributors: G. Zhang n, L. Truong *, R. Tanguay * & D. Reif n
TL;DR:
It is concluded that appropriate design and analysis of integrated morphological and behavioral studies using zebrafish can elucidate new chemical bioactivity pathways, identify compounds eliciting a broad range of effects, and paint a more comprehensive picture of development than either class of phenotype alone.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2017 journal article
An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines
Frontiers in Pharmacology, 8(APR).
Contributors: K. Roell n, D. Reif n & A. Motsinger-Reif n
author keywords: synergy; mixtures; non-additive; interactions; drug combinations
TL;DR:
The various terminology surrounding the idea of synergy is discussed, providing a comprehensive list of terms defined across numerous disciplines, including the two most prominent reference models for describing additive interactions: Loewe Additivity and Bliss Independence.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2017 journal article
A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades
Toxicology and Applied Pharmacology, 314, 109–117.
Contributors: G. Zhang n, K. Roell n, L. Truong *, R. Tanguay * & D. Reif n
author keywords: Zebrafish; High-dimensional; Bayesian; Developmental cascade; ToxRefDB; Risk assessment; Multiple endpoints; Multivariate; Scoring
MeSH headings : Animals; Models, Theoretical; Multivariate Analysis; Phenotype; Zebrafish / embryology
TL;DR:
The results suggest that developmental cascade effects triggered by chemical exposure can be recapitulated by analyzing the relationships among endpoints, and wAggE offers a powerful approach for analysis of multivariate phenotypes that can reveal underlying etiological processes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2019
2017 journal article
A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish
PLOS ONE, 12(1).
Contributors: G. Zhang n, L. Truong *, R. Tanguay * & D. Reif n
Ed(s): S. Neuhauss
MeSH headings : Animals; Biometry / methods; High-Throughput Screening Assays / methods; Models, Statistical; Zebrafish
TL;DR:
A novel, robust statistical approach to characterize chemical-elicited effects in behavioral data from high-throughput screening of all 1,060 Toxicity Forecaster chemicals across 5 concentrations at 120 hours post-fertilization (hpf) achieves a significant reduction in coefficient of variation compared to many traditional statistical modeling methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2019
2017 chapter
Uncertainty Quantification and Propagation for Projections of Extremes in Monthly Area Burned Under Climate Change: A Case Study in the Coastal Plain of Georgia, USA
In NATURAL HAZARD UNCERTAINTY ASSESSMENT: MODELING AND DECISION SUPPORT (Vol. 223, pp. 245–256).
UN Sustainable Development Goal Categories
13. Climate Action
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: December 31, 2018
2017 journal article
Sociality in wasps
Comparative Social Evolution, 84–123.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Socially controlled sex change in fishes
Hormones, Brain and Behavior, Vol 2: Non-Mammalian Hormone-Behavior Systems, 3rd Edition, 31–46.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Effect of intra-articular administration of superparamagnetic iron oxide nanoparticles (SPIONs) for MRI assessment of the cartilage barrier in a large animal model
PLOS ONE, 12(12).
MeSH headings : Animals; Biomarkers / metabolism; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / metabolism; Chemotaxis, Leukocyte; Coculture Techniques; Drug Administration Routes; Female; Fluorescent Dyes; Horses; Joints; Magnetic Resonance Imaging / methods; Magnetite Nanoparticles / administration & dosage; Male; Microscopy, Confocal; Models, Animal; Neutrophils / cytology; Swine
TL;DR:
Results demonstrate an increase in MRI signal following conditioning of porcine joints which suggests that nanoparticle dependent compositional cartilage imaging is feasible, and could potentially lead to a new diagnostic technique for early detection of cartilage disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Cradles and museums of Antarctic teleost biodiversity
NATURE ECOLOGY & EVOLUTION, 1(9), 1379–1384.
MeSH headings : Animals; Antarctic Regions; Biodiversity; Biological Evolution; Climate Change; DNA, Mitochondrial / genetics; Exons / genetics; Fishes / classification; Fishes / physiology; Introns / genetics; Phylogeny; Sequence Analysis, DNA
TL;DR:
Phylogenetic and biogeographic modelling show that high-latitude Antarctic nearshore habitats have been an evolutionary sink for species diversity of notothenioids, which dominate teleost fish diversity in the Southern Ocean.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 conference paper
Effects of evolutionary pressure on histone modifications
2017 ieee international conference on bioinformatics and biomedicine (bibm), 2267–2267.
TL;DR:
This simulation indicates that evolutionary selection pressure of an orthologous pair (Ka/Ks ratio) is more strongly correlated with its histone modification than any other similarity measure.
(via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2017 journal article
Development of selected reaction monitoring methods to systematically quantify kinase abundance and phosphorylation stoichiometry in human samples
Kinase Signaling Networks, 1636, 353–369.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Characterizing Sources of Uncertainty from Global Climate Models and Downscaling Techniques
JOURNAL OF APPLIED METEOROLOGY AND CLIMATOLOGY, 56(12), 3245–3262.
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
13. Climate Action
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Environmental endocrine disruption of brain and behavior
Hormones, Brain and Behavior, Vol 5: Development of Hormone-Behavior Relationships, 3rd Edition, 63–88.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Wildlife species preferences differ among children in continental and island locations
ENVIRONMENTAL CONSERVATION, 44(4), 389–396.
author keywords: wildlife preferences; cross-cultural; human dimensions; children; environmental education; conservation
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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