Works Published in 2018

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Displaying works 61 - 80 of 232 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

The evolution of tail weaponization in amniotes

Proceedings of the Royal Society B: Biological Sciences, 285(1871), 20172299.

author keywords: correlated evolution; weapons; dinosauria; cingulata
MeSH headings : Adaptation, Biological; Animals; Biological Evolution; Mammals / anatomy & histology; Mammals / physiology; Phylogeny; Reptiles / anatomy & histology; Reptiles / physiology; Tail / anatomy & histology; Tail / physiology; Weapons
TL;DR: It is suggested that the evolution of tail weaponry is rare because large, armoured herbivores are uncommon in extant terrestrial faunas, as they have been throughout evolutionary history. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 28, 2019

2018 article

Fitness Benefits of Loss of Heterozygosity in Saccharomyces Hybrids

Lancaster, S. M., Payen, C., Heil, C. S., & Dunham, M. J. (2018, October 25). (Vol. 10). Vol. 10.

By: S. Lancaster*, C. Payen*, C. Heil* & M. Dunham*

UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: ORCID
Added: September 12, 2019

2018 article

Temperature preference biases parental genome retention during hybrid evolution

Heil, C. S., Large, C. R. L., Patterson, K., & Dunham, M. J. (2018, September 27). (Vol. 9). Vol. 9.

TL;DR: This work investigates how the environment, and more specifically temperature, interacts with hybrid genomes to alter parental genome representation over time, and shows that a large contribution to this directionality is due to temperature sensitivity at a single locus, the high affinity phosphate transporter PHO84. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: ORCID
Added: September 12, 2019

2018 journal article

Disparate Growth Strategies within Aetosauria: Novel Histologic Data from the Aetosaur Coahomasuchus chathamensis.

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology, 302(9), 1504–1515.

author keywords: histology; osteoderms; paleobiology; pseudosuchia; archosaurs
MeSH headings : Animals; Bone and Bones / anatomy & histology; Bone and Bones / physiology; Fossils / anatomy & histology; Reptiles / anatomy & histology; Reptiles / growth & development
TL;DR: A histological examination of Coahomasuchus chathamensis is undertaken to address its ontogenetic trajectory and characterize its histology, revealing the presence of disparate growth strategies within Aetosauria. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: NC State University Libraries, Web Of Science
Added: September 12, 2019

2018 journal article

A new iguanodontian (Dinosauria: Ornithopoda) from the Early Cretaceous of Mongolia

PeerJ, 6, e5300.

author keywords: Dinosaur; Ornithopod; Evolution; Asia; Anatomy; Biodiversity; Phylogeny; Histology; Ontogeny; Paleontology
TL;DR: Differences in morphology and results of the phylogenetic analyses support their distinction although more specimens of both species will allow better refinement of their uniqueness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 12, 2019

2018 journal article

Nucleus accumbens core medium spiny neuron electrophysiological properties and partner preference behavior in the adult male prairie vole, Microtus ochrogaster

Journal of Neurophysiology, 119(4), 1576–1588.

By: J. Willett n, A. Johnson n, A. Vogel n, H. Patisaul n, L. McGraw n & J. Meitzen n

author keywords: electrophysiology; medium spiny neuron; nucleus accumbens; rat; vole
MeSH headings : Action Potentials / physiology; Animals; Arvicolinae / physiology; Excitatory Postsynaptic Potentials / physiology; Male; Mating Preference, Animal / physiology; Neurons / physiology; Nucleus Accumbens / physiology; Patch-Clamp Techniques; Social Behavior
TL;DR: It is found that decreases in miniature excitatory postsynaptic current amplitude and the slope of the evoked action potential firing rate to depolarizing current injection weakly associated with increased preference for the partnered female, suggests that exciteatory synaptic strength and neuronal excitability may be decreased in MSNs in males exhibiting stronger preference for a partnered female. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 17, 2019

2018 journal article

Individual Variation in Social Behaviours of Male Lab-reared Prairie voles (Microtus ochrogaster) is Non-heritable and Weakly Associated with V1aR Density

Scientific Reports, 8(1).

By: A. Vogel, H. Patisaul*, S. Arambula, F. Tiezzi & L. McGraw*

MeSH headings : Animals; Arvicolinae / physiology; Basal Forebrain / metabolism; Female; Male; Mating Preference, Animal; Pair Bond; Receptors, Vasopressin / metabolism; Social Behavior
TL;DR: Heritability estimates of variation in partner preference were low, yet heritability estimates for V1aR expression were high, indicating that the extensive variation in Partner preference observed within this population is due largely to environmental plasticity. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 17, 2019

2018 journal article

Environmental Mechanisms of Neurodevelopmental Toxicity

Current Environmental Health Reports, 5(1), 145–157.

author keywords: Neurodevelopment; Neurotoxicity; Xenobiotic; Neuroendocrine; Neuroimmune
MeSH headings : Brain / drug effects; Brain / growth & development; Environmental Exposure / adverse effects; Humans; Immune System / drug effects; Neurodevelopmental Disorders / chemically induced; Neurosecretory Systems / drug effects; Oxidative Stress / drug effects
TL;DR: Recent findings regarding novel mechanisms of developmental neurotoxicity are reported on and emerging areas of interest include neuroendocrine and immune disruption, as well as indirect toxicity via actions on other organs such as the gut and placenta are highlighted. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems

Basic & Clinical Pharmacology & Toxicology, 10.

author keywords: Bisphenol A; CLARITY-BPA; endocrine disruptor; endocrine-disrupting chemical; oestrogen
MeSH headings : Animals; Benzhydryl Compounds / toxicity; Congresses as Topic; Disease Models, Animal; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / toxicity; Environmental Exposure / adverse effects; Environmental Pollutants / toxicity; Female; Fetal Development / drug effects; Guidelines as Topic; Humans; National Institute of Environmental Health Sciences (U.S.) / standards; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / prevention & control; Rats, Sprague-Dawley; Risk Assessment / methods; Risk Assessment / standards; Toxicity Tests / methods; Toxicity Tests / standards; United States; United States Food and Drug Administration / standards
TL;DR: The findings highlighted herein corroborate a significant body of evidence that documents adverse effects of BPA at doses relevant to human exposures and emphasizes the need for updated risk assessment analysis. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy

BMC Research Notes, 11(1).

By: L. Stetzik*, A. Sullivan n, H. Patisaul n & B. Cushing*

MeSH headings : Animals; Arginine Vasopressin / genetics; Arginine Vasopressin / metabolism; Arvicolinae / physiology; Arvicolinae / psychology; Behavior, Animal / physiology; Cooperative Behavior; Dopaminergic Neurons / cytology; Dopaminergic Neurons / metabolism; Empathy / physiology; Female; Gene Expression; Humans; Hypothalamus / cytology; Hypothalamus / metabolism; Male; Models, Animal; Oxytocin / genetics; Oxytocin / metabolism; Paraventricular Hypothalamic Nucleus / cytology; Paraventricular Hypothalamic Nucleus / metabolism; Tyrosine 3-Monooxygenase / genetics; Tyrosine 3-Monooxygenase / metabolism
TL;DR: The consistency between neuroanatomical mechanisms linked to empathy, and the durations of time spent engaging in empathic contact, support the prediction that the empathy contact in this test is a distinct prosocial behavior, lacking prior behavioral training or the naturally occurring ethological relevance of other prosocial behaviors, and is a measure of empathy. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

Heavy Metal Exposure and Metabolic Syndrome: Evidence from Human and Model System Studies

Current Environmental Health Reports, 5(1), 110–124.

author keywords: Metabolic syndrome; Diabetes; Heavy metals; Cadmium; Pb; Mercury
MeSH headings : Animals; Cadmium / adverse effects; Disease Models, Animal; Humans; Lead / adverse effects; Mercury / adverse effects; Metabolic Syndrome / chemically induced; Metals, Heavy / adverse effects
TL;DR: Assessment of potential causal links between heavy metal exposure and metabolic syndrome remains challenging as epidemiological data are largely cross-sectional; and variation in study design, including samples used for heavy metal measurements, age of subjects at which MS outcomes are measured, and the population demographics vary widely. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 7, 2019

2018 journal article

Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study

International Journal of Obesity, 42(7), 1285–1295.

MeSH headings : Adipogenesis / drug effects; Animals; Cadmium / adverse effects; Cadmium / analysis; Cadmium / blood; Disease Models, Animal; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Humans; Infant, Newborn; Male; Maternal Exposure / adverse effects; Metals, Heavy / adverse effects; Metals, Heavy / analysis; Pediatric Obesity / blood; Pediatric Obesity / chemically induced; Pediatric Obesity / epidemiology; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / epidemiology; Prospective Studies; Socioeconomic Factors; United States / epidemiology; Zebrafish / metabolism
TL;DR: The findings identify Cd as a potential human obesogen, suggesting that the underlying mechanisms may be evolutionarily conserved, and that zebrafish may be a valuable model for uncovering pathways leading to Cd-mediated obesity in human populations. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: August 7, 2019

2018 journal article

Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure.

Environmental Health Perspectives, 6(6).

By: M. Balik-Meisner n, L. Truong*, E. Scholl n, D. La, R. Tanguay* & D. Reif n

Contributors: M. Balik-Meisner n, L. Truong*, E. Scholl n, J. La Du, R. Tanguay* & D. Reif n

MeSH headings : Animals; Embryo, Nonmammalian / drug effects; Embryonic Development / drug effects; Female; Gene-Environment Interaction; Genetic Variation; Genome-Wide Association Study; High-Throughput Screening Assays / methods; Ivermectin / analogs & derivatives; Ivermectin / toxicity; Male; Phenotype; Zebrafish / embryology; Zebrafish / genetics
TL;DR: The results for Abamectin in zebrafish demonstrate that GxE associated with naturally occurring, population genetic variation play a significant role in mediating individual response to chemical exposure. (via Semantic Scholar)
Source: ORCID
Added: May 14, 2019

2018 article

EPIGENOMICS AND HUMAN OBESITY

EPIGENETICS IN HUMAN DISEASE, 2ND EDITION, Vol. 6, pp. 409–426.

By: C. Hoyo n, D. Skaar n, S. Park n & P. Sorrow n

TL;DR: This chapter summarizes human data on CpG methylation, the most studied epigenetic mechanism in humans, in the context of causal inference, in adults and children, and concludes with a call for sex- and ethnic-specific data, together with data demonstrating that obesity-associated DNA methylation marks identified precede obesity. (via Semantic Scholar)
Source: Web Of Science
Added: April 22, 2019

2018 article

Modeling Dependence in Evolutionary Inference for Proteins

RESEARCH IN COMPUTATIONAL MOLECULAR BIOLOGY, RECOMB 2018, Vol. 10812, pp. 122–137.

By: G. Larson*, J. Thorne* & S. Schmidler n

author keywords: Protein structure; Evolution; Dynamic programming; Phylogeny; Diffusion process
TL;DR: It is demonstrated that this extended, site-dependent model (SDM), extended to account for correlated evolutionary drift among neighboring amino acid positions, yields a significant reduction of bias in estimated evolutionary distances and helps further improve phylogenetic tree reconstruction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: March 18, 2019

2018 journal article

Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes

NANOTOXICOLOGY, 12(9), 975–991.

By: K. Duke n, E. Thompson n, M. Ihrie n, A. Taylor-Just n, E. Ash n, K. Shipkowski n, J. Hall n, D. Tokarz n ...

author keywords: Caron nanotubes; immunotoxicology; cancer; granuloma; p53
MeSH headings : Animals; Dose-Response Relationship, Drug; Granuloma, Respiratory Tract / chemically induced; Granuloma, Respiratory Tract / genetics; Granuloma, Respiratory Tract / immunology; Inhalation Exposure; Lung / drug effects; Lung / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanotubes, Carbon / chemistry; Nanotubes, Carbon / toxicity; Surface Properties; Tertiary Lymphoid Structures / chemically induced; Tertiary Lymphoid Structures / genetics; Tertiary Lymphoid Structures / immunology; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / physiology
TL;DR: Findings indicate that a combination of p53 deficiency and physicochemical characteristics including nanotube geometry are factors in susceptibility to MWCNT-induced lymphoid infiltration and granuloma formation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 4, 2019

2018 journal article

Snap-jaw morphology is specialized for high-speed power amplification in the Dracula ant, Mystrium camillae

ROYAL SOCIETY OPEN SCIENCE, 5(12).

author keywords: finite-element analysis; power amplification; ants; microCT; functional morphology
TL;DR: The kinematics and functional morphology of the Dracula ant, Mystrium camillae, who use a snap-jaw mechanism to quickly slide their mandibles across each other similar to a finger snap are examined, extending the understanding of animal speed and demonstrating how small changes in morphology can result in dramatic differences in performance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: February 11, 2019

2018 journal article

Construction of a Compact Low-Cost Radiation Shield for Air-Temperature Sensors in Ecological Field Studies

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (141).

author keywords: Environmental Sciences; Issue 141; Air temperature; climate change; data logger; thermochron; radiation shield; field studies
MeSH headings : Ecosystem; Humans; Radiation Protection / methods; Temperature
TL;DR: A detailed methodology for constructing a compact version of a previously described custom fabricated radiation shield, which is more accurate than other published shielding methods that attempt to minimize shield size or construction costs is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 11, 2019

2018 journal article

Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 6.

TL;DR: In this ethnically diverse cohort, maternal adherence to a Mediterranean diet in early pregnancy was associated with favorable neurobehavioral outcomes in early childhood and with sex-dependent methylation differences of MEG3, IGF2, and SGCE/PEG10 DMRs. (via Semantic Scholar)
Source: NC State University Libraries
Added: January 21, 2019

2018 journal article

Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis

CLINICAL PROTEOMICS, 15.

By: M. Schreeg n, H. Marr n, J. Tarigo n, M. Sherrill*, H. Outi*, E. Scholl n, D. Bird n, A. Vigil* ...

author keywords: Cytauxzoonosis; Cytauxzoon felis; Expression library immunization; Protein microarray; Piroplasmid; Vaccine
TL;DR: Protein microarray facilitated high-throughput identification of novel antigens, substantially increasing the pool of characterized C. felis Antigens and should be considered for development of C.Felis vaccines, diagnostics, and therapeutics. (via Semantic Scholar)
Source: Web Of Science
Added: January 14, 2019

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