Works Published in 2020
Displaying works 61 - 80 of 249 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
A CRISPR/Cas guide RNA design in silico activity
CourseSource, 7.
crispor.tefor.net (publisher PDF)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2020 journal article
Facilitating Long-Term Mentoring To Effectively Implement Active Learning Instruction: Formation of the Promoting Active Learning and Mentoring (PALM) Network †
Journal of Microbiology & Biology Education, 21(3).
TL;DR:
The foundation on which PALM was built is described and how a successful mentorship program can pave the way for educators to adapt and implement evidence-based practices like active learning in a college classroom is explained.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2020 journal article
Catalyzing rapid discovery of gold-precipitating bacterial lineages with university students
PeerJ, 8, e8925.
author keywords: Citizen science; Delftia; Microbiology; Bacterial lineages; Sequencing; Microbiology education; Undergraduate education; Public science; Metagenomics; Public engagement
TL;DR:
An interdisciplinary program to engage students from different courses in the sampling, identification and analysis of the DNA sequences of a unique yet common microbe, Delftia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2020 journal article
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
GENOME MEDICINE, 12(1).
author keywords: Body mass index; Childhood obesity; DNA methylation; Epigenetics
MeSH headings : Adolescent; Body Mass Index; Child; Child, Preschool; CpG Islands; Cross-Sectional Studies; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Fetal Blood; Humans; Male; Obesity / genetics; Parturition; Pediatric Obesity / genetics; Pregnancy
TL;DR:
The strength of the associations of DNA methylation at the 187 CpGs previously identified to be associated with adult BMI, increased with advancing age across childhood and adolescence in the authors' analyses, compatible with the hypothesis thatDNA methylation differences are mostly a consequence rather than a cause of obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis
TRANSLATIONAL PSYCHIATRY, 10(1).
MeSH headings : Adolescent; Attention Deficit Disorder with Hyperactivity / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Pregnancy; Prospective Studies; Schools
TL;DR:
Evidence is found that DNA methylation at birth is associated with ADHD, and future studies are needed to confirm the utility of methylation variation as biomarker and its involvement in causal pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method
PARTICLE AND FIBRE TOXICOLOGY, 17(1).
author keywords: Carbon nanotubes; Purification; Functionalization; Lung injury; Fibrosis
MeSH headings : Administration, Inhalation; Air Pollutants / toxicity; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cytokines / metabolism; Inhalation Exposure; Lung / drug effects; Lung Injury; Mice; Mice, Inbred C57BL; Nanotubes, Carbon / toxicity; Transforming Growth Factor beta1 / metabolism
TL;DR:
The purification method is an important determinant of lung toxicity induced by carboxyl- and amine-functionalized MWCNTs, as indicated by Raman spectroscopy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Ground-Dwelling Invertebrate Abundance Positively Related to Volume of Logging Residues in the Southern Appalachians, USA
FORESTS, 11(11).
author keywords: ants; arachnids; bioenergy; downed wood; invertebrates; insects; logging residue; woody biomass
TL;DR:
Woody debris in harvested sites is important for the conservation of a majority of the taxa studied, which is likely because of the unique microclimate offered near/under woody debris.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: December 14, 2020
2020 journal article
Energetics as a lens to understanding aquatic insect's responses to changing temperature, dissolved oxygen and salinity regimes
CURRENT OPINION IN INSECT SCIENCE, 41, 46–53.
MeSH headings : Animals; Aquatic Organisms / physiology; Insecta / physiology; Oxygen / analysis; Salinity; Stress, Physiological; Temperature; Water / chemistry
TL;DR:
Recent developments in understanding of how high temperatures, elevated salinities and low oxygen levels affect physiological processes, responses at the organismal level, and impacts on species interaction and community assembly are highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: December 14, 2020
2020 journal article
Effects of Prenatal Exposure to a Mixture of Organophosphhate Flame Ritardants on Placental Gene Expression and Serotonergic Innervaion in the Fetal Rat Brain
TOXICOLOGICAL SCIENCES, 176(1), 203–223.
author keywords: endocrine disruptors; endocrine toxicology; flame retardants; metabolome; neurotoxicity; developmental; neurotoxicology; neurotransmitter; developmental toxicity; prenatal; reproductive and developmental toxicology; developmental/teratology
MeSH headings : Animals; Brain / drug effects; Female; Fetal Development; Fetus; Flame Retardants / toxicity; Gene Expression; Humans; Male; Organophosphates; Organophosphorus Compounds; Placenta / metabolism; Plasticizers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Serotonin / metabolism
TL;DR:
Findings suggest that OPFRs have the potential to impact the 5-HTergic system in the fetal forebrain by disrupting placental Trp metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 14, 2020
2020 journal article
Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease
TOXICOLOGICAL SCIENCES, 177(2), 392–404.
author keywords: environmental health; chemical-induced pathways; air pollution; cardiovascular disease; database
MeSH headings : Air Pollutants / toxicity; Air Pollution; Cardiovascular Diseases / chemically induced; Environmental Exposure; Environmental Health; Humans; Toxicogenetics
TL;DR:
This paper systematically compute the genes, molecular mechanisms, and biological events for the environmental health association linking air pollution toxicants with two cardiovascular diseases as a test case and identifies 19 genes and 96 phenotypes shared between these two air pollutant-induced outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 14, 2020
2020 journal article
Activation of Lrrk2 and alpha-Synuclein in substantia nigra, striatum, and cerebellum after chronic exposure to arsenite
TOXICOLOGY AND APPLIED PHARMACOLOGY, 408.
author keywords: Lrrk2; alpha-Synuclein; Arsenite; Striatum; Substantia nigra; Cerebellum
MeSH headings : Animals; Arsenic Poisoning / genetics; Arsenic Poisoning / metabolism; Arsenic Poisoning / physiopathology; Arsenites / toxicity; Cerebellum / drug effects; Cerebellum / metabolism; Corpus Striatum / drug effects; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / metabolism; Male; Mice, Inbred C57BL; Muscle Strength / drug effects; Phosphorylation / drug effects; Substantia Nigra / drug effects; Substantia Nigra / metabolism; Transcriptome / drug effects; alpha-Synuclein / metabolism
TL;DR:
Chronic arsenite exposure altered transcripts of glutathione redox reactions and serotonin receptor signaling in striatum, axonal guidance signaling, NF-κB and androgen signaling in substantia nigra and mitochondrial dysfunction, oxidative phosphorylation, apoptosis and sirtuin signaling in the cerebellum.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 11, 2020
2020 journal article
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity
REPRODUCTIVE TOXICOLOGY, 96, 359–369.
author keywords: Developmental toxicity; Flame retardants; Benchmark dose; Lowest effect concentration; Neurotoxicity; Classification model
MeSH headings : Animals; Embryo, Nonmammalian; Embryonic Development / drug effects; Flame Retardants / toxicity; Models, Animal; Neurotoxicity Syndromes; Risk Assessment; Structure-Activity Relationship; Teratogens / chemistry; Teratogens / toxicity; Zebrafish
TL;DR:
Developmental zebrafish were sufficiently sensitive at detecting FRC structure-bioactivity impacts that this work illustrates the power of a multi-dimensional in vivo platform to expand the ability to predict the hazard potential of new compounds based on structural relatedness, ultimately leading to reliable toxicity predictions based on chemical structure.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: November 30, 2020
2020 journal article
Genotype by environment interaction for gene expression in Drosophila melanogaster
NATURE COMMUNICATIONS, 11(1).
MeSH headings : Animals; Drosophila melanogaster / genetics; Female; Gene Expression; Gene Expression Regulation; Gene Regulatory Networks; Gene-Environment Interaction; Genes, Insect; Genetic Variation; Genotype; Male; Quantitative Trait Loci; RNA-Seq; Temperature; Transcriptome
TL;DR:
It is shown that developing under different temperatures changes the genetic architecture of regulatory variation in Drosophila melanogaster gene expression yet the co- expression network remains robust, and data suggest that stabilizing selection on gene expression may promote co-expression network robustness.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 30, 2020
2020 journal article
Building the lac Operon: A Guided-Inquiry Activity Using 3D-Printed Models
JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION, 21(1).
TL;DR:
Encouraging preliminary data suggest that TTTs with guided-inquiry learning disproportionately benefit disadvantaged student populations and could serve as a tool in leveling the playing field when teaching abstract biological concepts in diverse educational settings.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 30, 2020
2020 journal article
Transcriptomic and life history responses of the mayfly Neocloeon triangulifer to chronic diel thermal challenge
SCIENTIFIC REPORTS, 10(1).
MeSH headings : Animals; Ephemeroptera / genetics; Ephemeroptera / physiology; Gene Expression Regulation; Heat-Shock Response / genetics; Heat-Shock Response / physiology; Temperature; Transcriptome
TL;DR:
The chronically stressed population had reduced expression of transcripts related to ATP synthesis, mitochondrial electron chain functions, gluconeogenesis and glycolytic processes while transcripts associated with cell adhesion, synaptic vesicle transport, regulation of membrane potential and lipid biosynthesis increased.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: November 30, 2020
2020 journal article
STEM BUILD: An Online Community To Decrease Barriers to Implementation of Inclusive Tactile Teaching Tools
JOURNAL OF MICROBIOLOGY & BIOLOGY EDUCATION, 21(1).
TL;DR:
The strengths and weaknesses of common strategies for employing physical models in undergraduate biology courses are outlined and a novel strategy that is developed to pair 3D-printed models with guided inquiry learning to create inclusive and interactive learning experiences are described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 30, 2020
2020 journal article
Assembly of whole-chromosome pseudomolecules for polyploid plant genomes using outbred mapping populations
NATURE GENETICS, 52(11), 1256-+.
MeSH headings : Algorithms; Chromosomes, Plant; Computer Simulation; Genetic Linkage; Genome, Plant; Genotype; Ipomoea / genetics; Plant Breeding; Poaceae / genetics; Polyploidy; Protein Array Analysis; Solanum tuberosum / genetics
TL;DR:
PolyGembler, a method for grouping and ordering contigs into complete pseudomolecules by combining long-read sequencing and genotype information from an outbred mapping population, improves the accuracy for assembly of polyploidy plant genomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: November 24, 2020
2020 journal article
An integrated tagging and catch-curve model reveals high and seasonally-varying natural mortality for a fish population at low stock biomass
FISHERIES RESEARCH, 232.
author keywords: Weakfish; Tagging; Fishing mortality; Natural mortality; Catch-curve; Integrated tag-return and catch-curve model
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science; OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: November 24, 2020
2020 journal article
LEPTOSPIRA, PARVOVIRUS, AND TOXOPLASMA IN THE NORTH AMERICAN RIVER OTTER (LONTRA CANADENSIS) IN NORTH CAROLINA, USA
JOURNAL OF WILDLIFE DISEASES, 56(4), 791–802.
author keywords: Disease; leptospirosis; Lontra canadensis; North Carolina; otter; parvovirus; toxoplasmosis
MeSH headings : Animals; Female; Leptospira / isolation & purification; Leptospirosis / epidemiology; Leptospirosis / microbiology; Leptospirosis / veterinary; Male; North Carolina / epidemiology; Otters / microbiology; Otters / parasitology; Otters / virology; Parvoviridae Infections / epidemiology; Parvoviridae Infections / veterinary; Parvoviridae Infections / virology; Parvovirus / isolation & purification; Toxoplasma / isolation & purification; Toxoplasmosis, Animal / epidemiology; Toxoplasmosis, Animal / parasitology; Zoonoses
TL;DR:
Although the pathogens for parvovirus and toxoplasmosis are relatively common in North Carolina otters, the otter harvest has remained steady and the population appears to be abundant and self-sustaining.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020
2020 journal article
Exploring the Limits of Combined Image/'omics Analysis for Non-cancer Histological Phenotypes
FRONTIERS IN GENETICS, 11.
author keywords: imaging; genomics; pathology; prediction; integration; histology; machine learning; embedding
TL;DR:
This study surveys the evidence for genomic association and prediction of histology, and uses the results to test the limits of prediction accuracy using machine learning methods applied to the imaging data, genomics data, and their combination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020
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