Works Published in 2015
Displaying works 81 - 100 of 255 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Exudativory in the Asian Loris, Nycticebus: Evolutionary Divergence in the Toothcomb and M-3
American Journal of Physical Anthropology, 158(4), 663–672.
Contributors: A. Burrows *, A. Hartstone-Rose* & L. Nash*
author keywords: loris; slow loris; slender loris; gums; feeding; teeth
MeSH headings : Animals; Biological Evolution; Feeding Behavior; Female; Gingiva / physiology; Lorisidae / anatomy & histology; Lorisidae / physiology; Male; Plant Exudates; Tooth / anatomy & histology; Tooth / physiology
TL;DR:
The present study indicates that the toothcomb is the likely candidate for the dental tool used in gouging in slow lorises, and the size reduction of the lower last molar in Nycticebus may indicate that there is reduced selective pressure in a diet where little mastication would be needed to mechanically process exudates.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2015 journal article
Craniomandibular Signals of Diet in Adapids
American Journal of Physical Anthropology, 158(4), 646–662.
Contributors: J. Perry, E. St Clair & A. Hartstone-Rose*
author keywords: Adapis; bite force; chewing muscles; food; gape
MeSH headings : Animals; Anthropology, Physical; Bite Force; Feeding Behavior / physiology; Mandible / anatomy & histology; Mandible / physiology; Muscle, Skeletal / physiology; Skull / anatomy & histology; Skull / physiology; Strepsirhini / anatomy & histology; Strepsirhini / physiology
TL;DR:
Estimates of jaw adductor muscle mass, physiological cross-sectional area (PCSA), and fiber length in adapid primates from the Eocene of Europe support the inference that Adapis and Leptadapis were primarily folivorous, perhaps also consuming small to medium-sized tough fruits, nuts, and seeds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: September 12, 2019
2015 journal article
Complete description of the skull and mandible of the giant mustelid Eomellivora piveteaui Ozansoy, 1965 (Mammalia, Carnivora, Mustelidae), from Batallones (MN10), late Miocene (Madrid, Spain)
Journal of Vertebrate Paleontology, 35(4).
Contributors: A. Valenciano *, J. Abella *, O. Sanisidro *, A. Hartstone-Rose* , M. Angeles Alvarez-Sierra * & J. Morales *
TL;DR:
Cranial, mandibular, and dental remains of five individuals of the giant mustelid Eomellivora piveteaui Ozansoy, 1965 are described from the late Miocene site of Cerro de los Batallones (Madrid, Spain)—the first complete cranial remains recorded for this species and the most complete remains of the genus.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2015 journal article
Comparing apples and oranges-the influence of food mechanical properties on ingestive bite sizes in lemurs
American Journal of Physical Anthropology, 157(3), 513–518.
Contributors: A. Hartstone-Rose* , J. Parkinson*, T. Criste* & J. Perry*
author keywords: strepsirrhine; allometry; toughness; Young's modulus; gape; bite force
MeSH headings : Animals; Anthropology, Physical; Bite Force; Elastic Modulus; Feeding Behavior / physiology; Fruit / physiology; Lemur / physiology; Mastication / physiology; Vegetables / physiology
TL;DR:
This study quantified Vb in five species of lemurs at the DLC representing large and small frugivores and folivores using ten types of food that vary widely in stiffness and toughness to determine how these properties relate to bite sizes.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2015 journal article
Chinese Herbal Compounds for the Prevention and Treatment of Atherosclerosis: Experimental Evidence and Mechanisms
Evidence-Based Complementary and Alternative Medicine.
TL;DR:
The research that has been performed in recent years regarding the effectiveness and mechanisms of antiatherogenic Chinese herbal compounds in an attempt to build a bridge between traditional Chinese medicine and cellular and molecular cardiovascular medicine is summarized.
(via Semantic Scholar)
downloads.hindawi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 12, 2019
2015 journal article
Characterizing felid tooth marking and gross bone damage patterns using GIS image analysis: An experimental feeding study with large felids
Journal of Human Evolution, 80, 114–134.
Contributors: J. Parkinson*, T. Plummer * & A. Hartstone-Rose*
author keywords: Sabertooth; Taphonomy; Scavenging; Flesh availability; FLK Zinj
MeSH headings : Animals; Bone and Bones / injuries; Carnivory; Geographic Information Systems; Image Processing, Computer-Assisted; Lions; Tigers
TL;DR:
A typical pattern of bone damage resulting from large felid carcass modification, which can be distinguished from bone damage patterns produced by hyaenids and canids is identified, which consists of tooth marking largely restricted to limb bone ends and minimal bone fragmentation.
(via Semantic Scholar)
Source: ORCID
Added: September 12, 2019
2015 conference paper
Integrating literature-based curated data to predict mechanisms of toxicity
Presented at the OpenTox USA 2015, Baltimore, MD.
Event: OpenTox USA 2015 at Baltimore, MD on February 10-12, 2015
Source: NC State University Libraries
Added: August 10, 2019
2015 journal article
Food for Thought...: Toxicity testing in the 21st century beyond environmental chemicals
Altex, 32(3), 171–181.
Contributors: C. Rovida*, S. Asakura*, M. Daneshian*, H. Hofman-Huether*, M. Leist *, L. Meunier *, D. Reif n , A. Rossi*
author keywords: food ingredients; drugs; Tox21c; safety assessment
MeSH headings : Animal Testing Alternatives / methods; Animals; Drug Approval; Drug Evaluation / methods; Drug Industry; Humans; In Vitro Techniques; Risk Assessment; Safety / standards; Toxicity Tests / methods; United States; United States Environmental Protection Agency
TL;DR:
The question is whether the latest paradigm shift proposed by the Tox21c report for chemicals may provide a useful tool to improve the risk assessment approach also for drugs and food ingredients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: ORCID
Added: May 14, 2019
2015 book
Embracing complexity: Searching for gene-gene and gene environment interactions in genetic epidemiology
In Genomics and Proteomics: Principles, Technologies, and Applications (pp. 19–58).
Contributors: A. Motsinger & D. Reif
TL;DR:
Mango (Mangifera indica L.) is an important tropical fruit crop that is thought to be an allotetraploid species with an estimated genome size of 439 mega base pairs.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2015 journal article
Data-driven asthma endotypes defined from blood biomarker and gene expression data
PLoS ONE, 10(2).
Contributors: B. George *, D. Reif* , J. Gallagher*, C. Williams-DeVane *, B. Heidenfelder*, E. Hudgens*, W. Jones *, L. Neas *, E. Cohen Hubal *, S. Edwards*
MeSH headings : Adaptive Immunity; Anti-Asthmatic Agents / therapeutic use; Asthma / blood; Asthma / classification; Asthma / genetics; Asthma / immunology; Biomarkers / blood; Decision Trees; Eosinophilia / complications; Humans; Immunity, Innate; Medical Informatics / methods; Metabolic Syndrome / complications; Transcriptome
TL;DR:
This study describes four distinct asthma endotypes identified via a purely data-driven method, specifically designed to integrate blood gene expression and clinical biomarkers in a way that provides new mechanistic insights regarding the different asthma endotype.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2015 book
Computational Methods Used in Systems Biology
In Systems Biology in Toxicology and Environmental Health (pp. 85–115).
Contributors: M. Meisner & D. Reif*
TL;DR:
Progress in computational methods research has resulted in a trend toward standardization, where coalescence of statistical methods into powerful software packages handle early stages of analysis in a generally accepted manner.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2015 journal article
Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing
Reproductive Toxicology, 55, 3–10.
Contributors: N. Ducharme*, D. Reif n , J. Gustafsson* & M. Bondesson *
author keywords: Meta-analysis; Toxicity; Teratogen; Zebrafish; Human exposure
MeSH headings : Animal Testing Alternatives; Animals; Embryo, Nonmammalian / drug effects; Larva / drug effects; Lethal Dose 50; Mice; Rabbits; Rats; Toxicity Tests / methods; Zebrafish / embryology
TL;DR:
Ranking of the chemicals based on toxicity and teratogenicity in zebrafish, as well as human exposure levels, revealed that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), benzo(a)pyrene, and chlorpyrifos are considered high priority chemicals for testing in higher vertebrates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2019
2015 journal article
Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid.
The Lancet. Oncology, 8.
TL;DR:
This poster presents a poster presenting a poster presented at the 2015 European Congress of Oncology on how to select patients suitable for radiotherapy with a history of prior cancer treatment.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2015 journal article
Neurotranscriptome profiles of multiple zebrafish strains
GENOMICS DATA, 5, 206–209.
author keywords: RNA-sequencing; Brain; Gene expression; Sex; Zebrafish
TL;DR:
High throughput sequencing is utilized to characterize the neurotranscriptome profiles in both males and females across four strains of zebrafish (Danio rerio), varied by previously documented differences in stress and anxiety-like behavioral responses, and generations removed from wild-caught individuals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Estimated survival of subadult and adult Atlantic sturgeon in four river basins in the Southeastern United States
Marine and Coastal Fisheries (Online), 7(1), 514–522.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Inoculum optimization of Clostridium beijerinckii for reproducible growth
FEMS MICROBIOLOGY LETTERS, 362(19).
author keywords: Clostridium; inoculum; specific growth rate; quality curve; Clostridium beijerinckii; adaptation
MeSH headings : Butanols; Clostridium beijerinckii / growth & development; Culture Media; Ethanol; Fermentation; Industrial Microbiology / methods; Kinetics; Reproducibility of Results
TL;DR:
Evaluating the influence of inoculum age (harvest time) on the subsequent population's maximum specific growth rate, as a signal of population homogeneity, allowed us to understand the transient nature of seed cultures of C. beijerinckii NCIMB 8052 and SA-1, while enabling reproducibility and consistent culture performance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
A Geometric Morphometric Study of Regional Craniofacial Variation in Mexico
INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, 25(6), 795–804.
author keywords: geometric morphometrics; craniofacial variation; craniometrics
TL;DR:
The results from this analysis demonstrate that all groups are significantly different from one another supporting other findings that have shown that the indigenous populations of the New World are heterogeneous and that this variation may also contribute to the heterogeneity of contemporary populations.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Toxicological responses of environmental mixtures: Environmental metal mixtures display synergistic induction of metal-responsive and oxidative stress genes in placental cells
TOXICOLOGY AND APPLIED PHARMACOLOGY, 289(3), 534–541.
Contributors: O. Adebambo n, P. Ray*, D. Shea n & R. Fry *
author keywords: Toxicogenomics; Biomarkers; Real-world mixtures; Gene expression; Synergism; mRNA
MeSH headings : Arsenic / toxicity; Cadmium / toxicity; Cell Line, Tumor; China; Dose-Response Relationship, Drug; Female; Heavy Metal Poisoning; Humans; Metallothionein / metabolism; Metals, Heavy / toxicity; Oxidative Stress / drug effects; Oxidative Stress / genetics; Placenta / drug effects; Placenta / metabolism; Poisoning; Pregnancy; Water Pollutants, Chemical / toxicity
TL;DR:
It is demonstrated that metal mixtures increase the expression of gene biomarkers in placental JEG-3 cells in a synergistic manner, suggesting that toxic metals that co-occur may induce detrimental health effects that are currently underestimated when analyzed as single metals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Study on the performance of different craniofacial superimposition approaches (I)
FORENSIC SCIENCE INTERNATIONAL, 257, 496–503.
author keywords: Forensic anthropology; Craniofacial superimposition; MEPROCS; Craniofacial identification
MeSH headings : Datasets as Topic; Decision Making; Face / anatomy & histology; Female; Forensic Anthropology / methods; Humans; Imaging, Three-Dimensional; Male; Photography; Reproducibility of Results; Skull / anatomy & histology; Software
TL;DR:
This study aims to analyse the performance of a diverse set of CFS methodologies and the corresponding technical approaches when dealing with a common dataset of real-world cases to better understand the most convenient characteristics of every method included in this study.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Role of Signal Transducer and Activator of Transcription 1 in Murine Allergen-Induced Airway Remodeling and Exacerbation by Carbon Nanotubes
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 53(5), 625–636.
author keywords: asthma; allergen; nanomaterials; carbon nanotubes; airway remodeling
MeSH headings : Allergens / pharmacology; Animals; Bronchoalveolar Lavage Fluid / chemistry; Eosinophils / drug effects; Eosinophils / immunology; Eosinophils / pathology; Epithelial Cells / drug effects; Epithelial Cells / immunology; Epithelial Cells / pathology; Gene Expression Regulation; Goblet Cells / drug effects; Goblet Cells / immunology; Goblet Cells / pathology; Interleukin-10 / genetics; Interleukin-10 / immunology; Interleukin-13 / genetics; Interleukin-13 / immunology; Male; Mice; Mice, Knockout; Nanotubes / adverse effects; Neutrophils / drug effects; Neutrophils / immunology; Neutrophils / pathology; Osteopontin / genetics; Osteopontin / immunology; Ovalbumin / immunology; Respiratory Hypersensitivity / etiology; Respiratory Hypersensitivity / genetics; Respiratory Hypersensitivity / immunology; Respiratory Hypersensitivity / pathology; STAT1 Transcription Factor / deficiency; STAT1 Transcription Factor / genetics; STAT1 Transcription Factor / immunology; Signal Transduction; T-Lymphocytes, Helper-Inducer / drug effects; T-Lymphocytes, Helper-Inducer / immunology; T-Lymphocytes, Helper-Inducer / pathology; Transforming Growth Factor beta1 / genetics; Transforming Growth Factor beta1 / immunology; Transforming Growth Factor beta1 / pharmacology; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / immunology
TL;DR:
A protective role for STAT1 is supported in chronic AAI and exacerbation of remodeling caused by MWCNTs and fibroblasts isolated from the lungs of Stat1(-/-) mice produced significantly more collagen mRNA and protein in response to transforming growth factor-β1 compared with WT lung fibro Blasts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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