Works Published in 2018
Displaying works 101 - 120 of 232 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Local Auxin Biosynthesis Is a Key Regulator of Plant Development
DEVELOPMENTAL CELL, 47(3), 306-+.
MeSH headings : Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; Biological Transport; Ethylenes / metabolism; Flowers / metabolism; Gene Expression Regulation, Plant / genetics; Indoleacetic Acids / metabolism; Meristem / embryology; Meristem / metabolism; Morphogenesis; Oxygenases; Plant Development / genetics; Plant Growth Regulators / genetics; Plant Growth Regulators / metabolism; Plant Roots / embryology; Plant Roots / genetics; Plant Roots / metabolism; Spatio-Temporal Analysis
TL;DR:
This study systematically addressed the role of local auxin biosynthesis in plant development and responses to the stress phytohormone ethylene by manipulating spatiotemporal patterns of WEI8 and revealed that local auxIn biosynthesis and transport act synergistically and are individually dispensable for root meristem maintenance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: November 26, 2018
2018 journal article
The ligamentum teres femoris in orangutans
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, 167(3), 684–690.
author keywords: fovea capitis; ligament of the femoral head; Pongo; round ligament of the femur
MeSH headings : Animals; Anthropology, Physical; Female; Femur / anatomy & histology; Femur / physiology; Hip Joint / anatomy & histology; Hip Joint / physiology; Male; Pongo / anatomy & histology; Pongo / physiology; Range of Motion, Articular / physiology; Round Ligament of Femur / anatomy & histology; Round Ligament of Femur / physiology
TL;DR:
It is suggested that the LTF maintains a role in blood supply to the femoral head early in life and may explain why the L TF may be lost as an orangutan ages and gains locomotor independence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 19, 2018
2018 journal article
Machine Learning Reveals Protein Signatures in CSF and Plasma Fluids of Clinical Value for ALS
SCIENTIFIC REPORTS, 8.
MeSH headings : Amyotrophic Lateral Sclerosis / blood; Amyotrophic Lateral Sclerosis / cerebrospinal fluid; Amyotrophic Lateral Sclerosis / metabolism; Humans; Machine Learning; Multivariate Analysis; Proteomics
TL;DR:
The potential of a panel of targeted proteins for objective measurements of clinical value in ALS is demonstrated, and three proteins composed a prognostic model that explained 49% of the variation in the ALS-FRS scores.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Source: Web Of Science
Added: November 19, 2018
2018 journal article
Taxon cycle predictions supported by model-based inference in Indo-Pacific trap-jaw ants (Hymenoptera: Formicidae: Odontomachus)
MOLECULAR ECOLOGY, 27(20), 4090–4107.
author keywords: biogeography; diversification; Formicidae; insect; Melanesia; taxon cycle
MeSH headings : Animals; Ants / classification; Ants / genetics; Ecosystem; Phylogeny; Phylogeography
TL;DR:
There is strong evidence that habitat shifts from forest interior to open and disturbed habitats increased macroevolutionary dispersal rate and the phylogenetic predictions outlined in this study can be used in future work to evaluate the relative weights of neutral and non‐neutral processes in historical biogeography and community ecology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: November 12, 2018
2018 journal article
The influence of Neanderthal alleles on cytotoxic response
PEERJ, 6.
author keywords: Neanderthal alleles; Cytotoxic response; Pharmacogenomics; Toxicogenomics; Dose responses; Neanderthal ancestry; Lymphoblastoid cell lines; Anti-cancer drugs; Environmental chemicals; Single nucleotide polymorphisms
TL;DR:
The results demonstrate the influence of Neanderthal ancestry-informative markers on cytotoxic response and could be important in identifying biomarkers for personalized medicine or in dissecting the underlying etiology of dose response traits.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 5, 2018
2018 journal article
Estrous cycle-induced sex differences in medium spiny neuron excitatory synaptic transmission and intrinsic excitability in adult rat nucleus accumbens core
JOURNAL OF NEUROPHYSIOLOGY, 120(3), 1356–1373.
author keywords: estrous cycle; excitability; medium spiny neurons; nucleus accumbens; sex steroid hormones
MeSH headings : Action Potentials; Animals; Castration; Estrous Cycle; Excitatory Postsynaptic Potentials; Female; Male; Neurons / physiology; Nucleus Accumbens / physiology; Rats, Sprague-Dawley; Sex Characteristics
TL;DR:
It is the first demonstration that medium spiny neuron electrophysiological properties change across adult female hormone cycle phases in any striatal region and indicates that adultFemale hormone cycles are an important factor for neurophysiology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: November 5, 2018
2018 journal article
Palmitoylation of caveolin-1 is regulated by the same DHHC acyltransferases that modify steroid hormone receptors
JOURNAL OF BIOLOGICAL CHEMISTRY, 293(41), 15901–15911.
author keywords: estrogen receptor; post-translational modification (PTM); protein palmitoylation; caveolin; membrane protein; DHHC
MeSH headings : Acetyltransferases; Acyltransferases / genetics; Acyltransferases / metabolism; Animals; Caveolin 1 / metabolism; Cyclic AMP Response Element-Binding Protein / metabolism; Female; Gene Knockdown Techniques; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins / genetics; Intracellular Signaling Peptides and Proteins / metabolism; Lipoylation; Protein Processing, Post-Translational; Rats, Sprague-Dawley
TL;DR:
Findings provide additional information about the overall influence of palmitoylation on the membrane-initiated estrogen signaling pathway and highlight the importance of considering the influence ofPalmitoylated proteins on other CAV1-dependent processes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 29, 2018
2018 journal article
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event
Cell Death & Disease, 9(11).
MeSH headings : 9,10-Dimethyl-1,2-benzanthracene / administration & dosage; Animals; Apoptosis / drug effects; Apoptosis / genetics; CCAAT-Enhancer-Binding Protein-beta / deficiency; CCAAT-Enhancer-Binding Protein-beta / genetics; Cell Differentiation; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Mice; Mice, Knockout; Receptors, Death Domain / genetics; Receptors, Death Domain / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Neoplasms / chemically induced; Skin Neoplasms / genetics; Skin Neoplasms / metabolism; Skin Neoplasms / pathology; Tetradecanoylphorbol Acetate / administration & dosage; Tetradecanoylphorbol Acetate / analogs & derivatives; Tumor Suppressor Protein p53 / genetics; Tumor Suppressor Protein p53 / metabolism; ras Proteins / genetics; ras Proteins / metabolism
TL;DR:
The results show that oncogenic Ras tumors display a significant DNA damage/replicative stress phenotype and these tumors have acquired a dependence on C/EBPβ for their survival, making it a promising target for future potential anticancer therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: October 29, 2018
2018 review
Enhancing and Extending Biological Performance and Resilience
[Review of ]. DOSE-RESPONSE, 16(3).
author keywords: preconditioning; conditioning; adaptation; hormesis; stress; tolerance; biphasic; dose-response; U-shaped; J-shaped; fitness; endurance; epigenetics; dietary restriction; caloric restriction
TL;DR:
A path forward is proposed for researchers hoping to optimize protocols that support human health and longevity, whether in civilians, soldiers, athletes, or the elderly patients, by recommending approaches to control and exploit endogenous defense mechanisms to enhance the structure and function of biological tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Thermal regime drives a latitudinal gradient in morphology and life history in a livebearing fish
BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY, 125(1), 126–141.
author keywords: body size; Bergmann's rule; Gambusia holbrooki; population density; productivity; temperature gradient
TL;DR:
This work aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the dynamic response of the immune system to infectious disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Relationship Between Sequence Homology, Genome Architecture, and Meiotic Behavior of the Sex Chromosomes in North American Voles
GENETICS, 210(1), 83–97.
author keywords: pseudoautosomal region; Microtus heterochromatin; telomeric repeats; meiotic synapsis
MeSH headings : Animals; Arvicolinae / genetics; Chromosome Segregation / genetics; Genomics / methods; Meiosis / genetics; North America; Pseudoautosomal Regions / genetics; Sequence Analysis, DNA / methods; Sequence Homology, Nucleic Acid; Sex Chromosomes / genetics; Telomere / genetics; Telomere-Binding Proteins / genetics; X Chromosome / genetics; Y Chromosome / genetics
TL;DR:
Key conditions required to sustain the standard program of X/Y synapsis at meiosis are suggested and an intriguing connection between heterochromatic repeat architecture and noncanonical, asynaptic mechanisms of sex chromosome segregation in voles is revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: October 19, 2018
2018 article
Challenges of implementing Mark-recapture studies on poorly marked gregarious delphinids (vol 13, e0198167, 2018)
Hupman, K., Stockin, K. A., Pollock, K., Pawley, M. D. M., Dwyer, S. L., Lea, C., & Tezanos-Pinto, G. (2018, August 28). PLOS ONE, Vol. 13.
TL;DR:
This research presents a novel probabilistic approach to estimating the response of the immune system to laser-spot assisted, 3D image analysis of central nervous system injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Leptin Stimulates Cellular Glycolysis Through a STAT3 Dependent Mechanism in Tilapia
FRONTIERS IN ENDOCRINOLOGY, 9.
author keywords: leptin; prolactin cell; hepatocytes; pituitary; RNAseq; fishes; phosphofructokinase-1
TL;DR:
It is suggested that one of leptin's ancient, highly-conserved functions among vertebrates may be stimulation of glycolysis to facilitate the energetic needs associated with various stressors in a teleost fish.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: October 19, 2018
2018 review
Applications of Augmented Reality in Informal Science Learning Sites: a Review
[Review of ]. JOURNAL OF SCIENCE EDUCATION AND TECHNOLOGY, 27(5), 433–447.
author keywords: Augmented reality; Informal learning sites; AR review; STEM learning
TL;DR:
A review of research on the incorporation of augmented reality at exhibit-based informal science education (ISE) settings in the literature to foster continued development and implementation of AR technology in exhibit- based ISE settings by informing the community of recent findings and promoting additional rigorous research for the future.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018
2018 journal article
Germination Responses of Ryegrass (Annual vs. Perennial) Seed to the Interactive Effects of Temperature and Salt-Alkali Stress
FRONTIERS IN PLANT SCIENCE, 9.
author keywords: annual ryegrass; perennial ryegrass; temperature; salinity-alkalinity; germination recovery
TL;DR:
The results suggest that salinity stress and alkalinity stress are greatly different, and the salt-alkaline tolerance of ryegrass seeds is greatly affected by the interactions of temperature and salinity–alkalinity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: October 19, 2018
2018 journal article
Assessment of growth, survival, and organ tissues of caged mussels (Bivalvia: Unionidae) in a river-scape influenced by coal mining in the southeastern USA
SCIENCE OF THE TOTAL ENVIRONMENT, 645, 1273–1286.
author keywords: Clinch River; Histology; Freshwater mussels; Chemical mixtures; Lipid peroxidation; Kidney lipofuscin
MeSH headings : Animals; Bivalvia / physiology; Coal Mining; Environmental Monitoring / methods; Fresh Water; Rivers; Unionidae; Water Pollutants, Chemical / analysis
TL;DR:
These results suggest that conditions continue to exist in the zone of decline that promote impacts to mussels that are at least partially associated with low concentration coal-related contaminants.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018
2018 article
RUMINANT NUTRITION SYMPOSIUM: Tiny but mighty: the role of the rumen microbes in livestock production (vol 96, pg 752, 2018)
Cammack, K. M., Austin, K. J., Lamberson, W. R., Conant, G. C., & Cunningham, H. C. (2018, October). JOURNAL OF ANIMAL SCIENCE, Vol. 96, pp. 4481–4481.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018
2018 journal article
Estimation of cis-eQTL effect sizes using a log of linear model
BIOMETRICS, 74(2), 616–625.
author keywords: eQTL analyses; EQTL effect size; Multiple testing; Nonlinear regression
MeSH headings : Algorithms; Alleles; Gene Expression; Humans; Linear Models; Quantitative Trait Loci; Statistics as Topic
TL;DR:
A new, log‐of‐linear model for eQTL action is proposed, termed ACME, that captures allelic contributions to cis‐acting eZTLs in an additive fashion, yielding effect size estimates that correspond to a biologically coherent model of cis‐eQTLs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018
2018 journal article
Relation of contaminants to fish intersex in riverine sport fishes
SCIENCE OF THE TOTAL ENVIRONMENT, 643, 73–89.
author keywords: Endocrine active compounds; Endocrine disruption; Bass; Polycyclic aromatic hydrocarbons; Ethinylestradiol; Mercury
MeSH headings : Animals; Disorders of Sex Development / epidemiology; Disorders of Sex Development / veterinary; Environmental Monitoring; Female; Fish Diseases / epidemiology; Fishes / physiology; Male; North Carolina; Rivers / chemistry; South Carolina; Sports; Water Pollutants, Chemical / analysis; Water Pollution, Chemical / statistics & numerical data
TL;DR:
Polycyclic aromatic hydrocarbons, ethinylestradiol, and heavy metals were the most prevalent contaminants that exceeded effect levels for the protection of aquatic organisms and principal component analysis identified waterborne PAHs as the most correlated environmental contaminant with intersex occurrence and severity in black bass and sunfish.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 16, 2018
2018 article
Epigenetic Responses to Low Dose Ionizing Radiation
Jirtle, R. L. (2018, August 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 124, pp. 559–559.
TL;DR:
This animal model has been used to demonstrate that nutritional and chemical toxicant exposures during early development induce persistent epigenetic changes at the Avy locus that result in alterations in coat color and adult disease susceptibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: October 16, 2018
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