Works Published in 2004
Displaying works 1 - 20 of 134 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2004 chapter
Use classes: metals, agricultural chemicals, food additives and contaminants, toxins, solvents, therapeutic drugs, drugs of abuse, combustion products, and cosmetics
In E. Hodgson (Ed.), A Textbook of Modern Toxicology (3rd ed., pp. 49–74). Hoboken, NJ: John Wiley & Sons, Inc.
Ed(s): E. Hodgson
Source: NC State University Libraries
Added: September 23, 2022
2004 report
Understanding the Agricultural Health Study, Part 1: Overview
(North Carolina State University Cooperative Extension Service No. AG-MED-24). Raleigh, NC: North Carolina State University Cooperative Extension Service Press.
Source: NC State University Libraries
Added: September 23, 2022
2004 report
Understanding the Agricultural Health Study, Part 2: Pesticide Exposure
(North Carolina State University Cooperative Extension Service No. AG-MED-25). Raleigh, NC: North Carolina State University Cooperative Extension Service Press.
Source: NC State University Libraries
Added: September 23, 2022
2004 report
Understanding the Agricultural Health Study, Part 3: Health Findings
(North Carolina State University Cooperative Extension Service No. AG-MED-26). Raleigh, NC: North Carolina State University Cooperative Extension Service Press.
Source: NC State University Libraries
Added: September 23, 2022
2004 chapter book
Exposure Classes, Toxicants in Air, Water, Soil, Domestic and Occupational Settings
Sources: Crossref, NC State University Libraries
Added: September 16, 2022
2004 chapter book
Bioinformatics Tools
Sources: Crossref, NC State University Libraries
Added: September 13, 2022
2004 journal article
Fluorescent proteins expressed in mouse transgenic lines mark subsets of glia, neurons, macrophages, and dendritic cells for vital examination.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience.
author keywords: neuromuscular junction; Schwann cell; microglia; Langerhans cell; astrocyte; S100 beta; S100B; motor neuron; variegation; Bergmann glia
MeSH headings : Adipocytes / cytology; Animals; Cell Line; Dendritic Cells / cytology; Green Fluorescent Proteins / biosynthesis; Humans; Langerhans Cells / cytology; Lens, Crystalline / cytology; Luminescent Proteins / biosynthesis; Macrophages / cytology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Nerve Growth Factors; Neuroglia / cytology; Neuromuscular Junction / cytology; Neurons / cytology; Receptors, Cholinergic / analysis; Recombinant Fusion Proteins / biosynthesis; S100 Calcium Binding Protein beta Subunit; S100 Proteins / biosynthesis; S100 Proteins / genetics; Schwann Cells / chemistry; Schwann Cells / cytology; Schwann Cells / ultrastructure; Transgenes
TL;DR:
It is shown that lines with labeled macrophages can be used to follow the accumulation of these cells at sites of injury and suggests that Schwann cells at individual synapses are clonally related, a finding with implications for how these cells might be sorted during postnatal development.
(via Semantic Scholar)
www.jneurosci.org (publisher PDF)
Source: ORCID
Added: September 6, 2022
2004 chapter
Chemical Carcinogenesis
In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 225–250).
Ed(s): E. Hodgson
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: April 9, 2022
2004 journal article
In-gel precipitation of enzymatically released phosphate.
Analytical Biochemistry.
Contributors: A. Simonovic *, S. Gaddameedhi* & M. Anderson *
author keywords: acid phosphatase; alkaline phosphatase; ammonium molybdate; apyrase; gel-based assay; glutamine synthetase; inorganic phosphate; maltose phosphorylase; native PAGE; orthophosphate; precipitation; triethylamine
MeSH headings : Chemical Precipitation; Gels; Glucosyltransferases / metabolism; Glutamate-Ammonia Ligase / isolation & purification; Glutamate-Ammonia Ligase / metabolism; Hydrogen-Ion Concentration; Hydrolases / metabolism; Isoenzymes / isolation & purification; Isoenzymes / metabolism; Phosphates / chemistry; Phosphates / metabolism; Sensitivity and Specificity; Substrate Specificity
TL;DR:
The phosphate precipitation reaction using ammonium molybdate and triethylamine under low pH has been applied to gel-based assays for detecting phosphate-releasing enzymes, a very simple, rapid, versatile, reproducible, and inexpensive method that could be a useful tool in enzymological studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: December 24, 2021
2004 journal article
Visualization of Antigen Presentation by Actin-Mediated Targeting of Glycolipid-Enriched Membrane Domains to the Immune Synapse of B Cell APCs
Journal of Immunology, 172(4), 2030–2038. http://www.scopus.com/inward/record.url?eid=2-s2.0-0842343443&partnerID=MN8TOARS
Contributors: C. Gordy , S. Mishra & W. Rodgers
Source: ORCID
Added: August 24, 2021
2004 journal article
Regulation of PDGF and its receptors in fibrotic diseases
Cytokine & Growth Factor Reviews, 15(4), 255–273.
author keywords: PDGF; fibrosis; lung; liver; kidney
MeSH headings : Animals; Fibroblasts / metabolism; Fibrosis / pathology; Gene Expression Regulation; Humans; Inflammation / pathology; Interleukin-1 / metabolism; Kidney / pathology; Liver / pathology; Lung / pathology; Models, Biological; Muscles / pathology; Platelet-Derived Growth Factor / metabolism; Platelet-Derived Growth Factor / physiology; Protein Isoforms; Receptor, Platelet-Derived Growth Factor alpha / metabolism; Receptor, Platelet-Derived Growth Factor beta / metabolism; Scleroderma, Systemic / pathology; Signal Transduction; Tissue Distribution; Transforming Growth Factor beta / metabolism; Transforming Growth Factor beta1
TL;DR:
This review summarizes the literature on the role of PDGF and its receptors in the development of fibrosis in a variety of organ systems, including lung, liver, kidney, and skin.
(via Semantic Scholar)
Source: Crossref
Added: August 14, 2021
2004 chapter
Transport and Fate of Toxicants in the Environment
In E. Hodgson (Ed.), Textbook of Modern Toxicology (3rd ed., pp. 479–499).
Ed(s): E. Hodgson
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: NC State University Libraries
Added: March 26, 2021
2004 chapter
Environmental Risk Assessment
In E. Hodgson (Ed.), A Textbook of Modern Toxicology (3rd ed., pp. 501–517).
Ed(s): E. Hodgson
Source: NC State University Libraries
Added: March 26, 2021
2004 journal article
The Splicing Graph – A Tool for Visualising Gene Structure and Alternative Splicing
Future Drug Discovery, 62–65.
Source: NC State University Libraries
Added: March 19, 2021
2004 conference paper
Multi-locus Linkage Disequilibrium and Haplotype-Based Tests of Association
Computational Methods for SNPs and Haplotype Inference, 139–139.
Event: DIMACS/RECOMB Satellite Workshop at Piscataway, New Jersey, USA on November 21-22, 2002
TL;DR:
Several tests of haplotype association are presented here, along with a comparison of these tests within different LD contexts, and there is no longer a simple relationship with recombination.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 5, 2021
2004 journal article
Inhibition of insulin-dependent glucose uptake by trivalent arsenicals: possible mechanism of arsenic-induced diabetes
Toxicology and Applied Pharmacology, 198(3), 424–433.
author keywords: arsenic; diabetes; methylation; glucose uptake; insulin; GLUT4; PKB; Akt
MeSH headings : Animals; Arsenicals / adverse effects; Arsenicals / metabolism; Arsenicals / pharmacology; Cell Survival / drug effects; Cells, Cultured; Diabetes Mellitus, Type 2 / chemically induced; Glucose / metabolism; Insulin / pharmacology; Methylation; Mice
TL;DR:
Results suggest that trivalent arsenicals inhibit insulin-stimulated glucose uptake by interfering with the PKB/Akt-dependent mobilization of GLUT4 transporters in adipocytes, which may be, in part, responsible for the development of type-2 diabetes in individuals chronically exposed to iAs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 25, 2021
2004 journal article
Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 15(3), 225–233.
author keywords: pesticides; farmers; custom applicators; factor analysis; herbicides; insecticides; fungicides; fumigants; Iowa; North Carolina
MeSH headings : Adult; Age Factors; Agriculture; Cohort Studies; Factor Analysis, Statistical; Female; Humans; Iowa; Life Style; Male; Middle Aged; Occupational Exposure; Pesticides / analysis; Risk Assessment; Spouses
TL;DR:
Heterogeneity in exposure patterns to pesticides did not correlate with lifestyle characteristics such as race, smoking status or education, which may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021
2004 journal article
Roles of uptake, biotransformation, and target site sensitivity in determining the differential toxicity of chlorpyrifos to second to fourth instar Chironomous riparius (Meigen)
Aquatic Toxicology, 66(2), 149–157.
author keywords: chlorpyrifos; acetylcholinesterase; biotransformation; life stages; Chironomous
MeSH headings : Acetylcholinesterase / metabolism; Animals; Chironomidae / metabolism; Chlorpyrifos / metabolism; Chlorpyrifos / pharmacokinetics; Chlorpyrifos / toxicity; Dose-Response Relationship, Drug; Down-Regulation / drug effects; Larva / metabolism; Toxicity Tests
TL;DR:
It appeared that chlorpyrifos sensitivity differences among second to fourth instar C. riparius were largely determined by differences in uptake rates, which could potentially offset the apparent increased sensitivity to the oxon.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2004 journal article
Estrogen receptor expression in a human primitive neuroectodermal tumor cell line from the cerebral cortex: estrogen stimulates rapid ERK1/2 activation and receptor-dependent cell migration
Biochemical and Biophysical Research Communications, 319(3), 753–758.
Contributors: M. Kirby*, A. Zsarnovszky* & S. Belcher*
author keywords: ER alpha; ER beta; ERK1/2; estrogen; estrogen receptor; growth; hormone responsive; MAPK; migration; non-genomic; PNET; signal transduction
MeSH headings : Animals; Brain Neoplasms / metabolism; Cell Line, Tumor; Cell Movement / physiology; Cerebral Cortex / metabolism; Cerebral Cortex / pathology; Enzyme Activation; Estrogens / metabolism; Humans; MAP Kinase Signaling System / physiology; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases / metabolism; Neuroectodermal Tumors, Primitive / metabolism; Receptors, Estrogen / metabolism; Transcriptional Activation
TL;DR:
Results of immunoblot studies using ER-specific antiserum indicate that both ERalpha and ERbeta are expressed in PFSK1 cells, suggesting that rapid actions of E(2) and ER-mediated processes might contribute to the metastatic phenotype of some PNETs.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: January 21, 2021
2004 journal article
Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression
Toxicology Letters, 150(3), 325–334.
Contributors: Y. Ge *, S. Belcher* , D. Pierce* & K. Light*
MeSH headings : Administration, Oral; Animals; Animals, Newborn; Calbindin 1; Calbindins; Cell Count; Dose-Response Relationship, Drug; Ethanol / toxicity; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / cytology; Purkinje Cells / drug effects; Purkinje Cells / metabolism; RNA, Messenger / biosynthesis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; S100 Calcium Binding Protein G / biosynthesis; Valproic Acid / toxicity
TL;DR:
Analysis of mRNA expression specific to calbindin-D28k by comparison to matched controls provides a reliable means of determining whether cell loss has occurred, regardless of whether the cell loss was induced by prenatal valproic acid or postnatal ethanol exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: January 21, 2021
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