Works Published in 2008

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Displaying works 1 - 20 of 163 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 chapter book

Fatty Acid Synthase Activity in Tumor Cells

By: J. Little* & S. Kridel*

MeSH headings : Animals; Antineoplastic Agents / pharmacology; Cell Cycle / drug effects; Enzyme Inhibitors / pharmacology; Fatty Acid Synthases / antagonists & inhibitors; Fatty Acid Synthases / metabolism; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Humans; Neoplasms / enzymology; Palmitic Acid / metabolism; Signal Transduction; Up-Regulation
TL;DR: Pharmacological blockade of FASN activity has identified a pleiotropic role for FASn in mediating aspects of proliferation, growth and survival, and a clearer understanding of the role of F ASN in tumor cells has been developed. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 2, 2023

2008 journal article

Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death

Molecular Cancer Therapeutics, 7(12), 3816–3824.

By: J. Little*, F. Wheeler*, C. Koumenis* & S. Kridel*

MeSH headings : Antigens, Differentiation / metabolism; Cell Cycle Proteins / metabolism; Cell Death; Cell Line, Tumor; DNA-Binding Proteins / metabolism; Dose-Response Relationship, Drug; Fatty Acid Synthase, Type I / metabolism; Fatty Acid Synthase, Type I / physiology; Fatty Acids / metabolism; Humans; Male; Models, Biological; Prostatic Neoplasms / drug therapy; Prostatic Neoplasms / pathology; Proteasome Endopeptidase Complex / metabolism; Protein Denaturation; Protein Phosphatase 1; Regulatory Factor X Transcription Factors; Signal Transduction; Transcription Factors / metabolism; Ubiquitin / metabolism
TL;DR: The data support the concept that the UPR balance between adaptive to stress signaling can be exploited to mediate increased cell death and suggests novel applications of FASN inhibitors for clinical use. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 1, 2023

2008 journal article

Deciphering the association between up-regulation of glucose regulated protein of Mr-78 kDa (GRP78) and hypersensitivity to cisplatin employing comparative genomics

The FASEB Journal. https://publons.com/wos-op/publon/54906423/

Contributors: S. Gaddameedhi & S. Chatterjee

Source: ORCID
Added: November 14, 2022

2008 report

Endocrine Disruptor Screening Program (EDSP) Proposed Tier 1 Screening Battery - Federal Insecticide, Fungicide, and Rodenticide Act Scientific Advisory Panel

Environmental Protection Agency.

By: S. Kullman

Source: NC State University Libraries
Added: September 16, 2022

2008 chapter

Liver Toxicity

In The Toxicology of Fishes (pp. 327–400).

By: D. Hinton, H. Segner, D. Au, S. Kullman* & R. Hardman

Sources: Crossref, ORCID
Added: September 15, 2022

2008 chapter

Biotransformation in Fishes

In The Toxicology of Fishes (pp. 153–234).

By: D. Schlenk, M. Celander, E. Gallagher, S. George, M. James, S. Kullman*, P. van den Hurk, K. Willett

Sources: Crossref, ORCID
Added: September 15, 2022

2008 journal article

Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications

Comparative Hepatology, 7(1).

By: R. Hardman*, S. Kullman* & D. Hinton*

TL;DR: The development of methodologies for non invasive in vivo investigation in STII medaka and the successful application of these methodologies to in vivo study of hepatobiliary structure, function, and xenobiotic response are described. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2022

2008 conference paper

PGA Accumulation and Biofilm Formation in Escherichia coli: Modulation by c-di-GMP

Poster presented at the 108th General Meeting of the American Society for Microbiology, Boston, MA.

By: C. Goller, A. Pannuri, T. Romeo, Y. Itoh & K. Suzuki

Event: 108th General Meeting of the American Society for Microbiology at Boston, MA on June 1-5, 2008

Source: NC State University Libraries
Added: June 3, 2022

2008 book

Molecular and Biochemical Toxicology

Robert Smart

Ed(s): R. Smart & E. Hodgson

TL;DR: This crucial new edition has been completely revised to provide timely and thorough coverage of the underlying biochemical, molecular, and cellular mechanisms through which toxicants produce their adverse effects. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: April 10, 2022

2008 chapter

Carcinogenesis

In Molecular and Biochemical Toxicology (4th ed., pp. 537–586).

By: R. Smart n, S. Ewing* & K. Loomis n

Sources: Crossref, ORCID
Added: April 9, 2022

2008 chapter

Overview of Molecular Techniques in Toxicology: Genes and Transgenes

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 5–24).

By: R. Smart n

Ed(s): R. Smart n & E. Hodgson

UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Crossref, ORCID
Added: April 9, 2022

2008 chapter

Molecular and Biochemical Toxicology: Definition and Scope

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 1–4).

By: E. Hodgson n & R. Smart n

Ed(s): R. Smart n & E. Hodgson n

Sources: Crossref, ORCID
Added: April 9, 2022

2008 conference paper

Design for a region-wide adaptive search for the ivorybilled woodpecker with the objective of estimating occupancy and related parameters

Tundra to Tropics: Connecting Birds, Habitats and People: 4th International Partners in Flight Conference, 13-16 February 2008, McAllen, Texas: Abstracts.

By: R. Cooper, R. Mordecai, B. Mattsson, M. Conroy, K. Pacifici, J. Peterson, C. Moore

Source: NC State University Libraries
Added: April 24, 2021

2008 report

An Adaptive Sample Survey Design for the Ivory-billed Woodpecker

(Cooperative Agreement No. 1434-02HQRU1551). http://usgs-cru-individual-data.s3.amazonaws.com/cmoore/tech_publications/Conroy%20et%20al%20(2008)%20IBWO%20Final%20Report-1.pdf

By: C. Moore, B. Mattsson, R. Mordecai, K. Pacifici, M. Conroy, J. Peterson, R. Cooper

Source: NC State University Libraries
Added: April 24, 2021

2008 conference paper

Linkage Analysis in American Staffordshire Terriers with Hereditary Cerebellar Cortical Degeneration

Journal of Veterinary Internal Medicine, 22(3), 723–724.

By: N. Olby, T. Harris, P. Mehta, M. Breen, R. Thomas, R. Myers, D. Nielsen

Event: 26th Annual American College of Veterinary Internal Medicine Forum at San Antonio, TX on June 4-7, 2008

Source: NC State University Libraries
Added: March 19, 2021

2008 chapter

Immunochemical Techniques in Toxicology

In E. Hodgson & R. C. Smart (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 109–128). Hoboken, New Jersey: John Wiley & Sons.

By: G. LeBlanc

Ed(s): E. Hodgson & R. Smart

Source: NC State University Libraries
Added: March 18, 2021

2008 book

Cardiovascular effects of steroidal agents

In Cardiovascular Toxicology, Fourth Edition (pp. 367–428). http://www.scopus.com/inward/record.url?eid=2-s2.0-85057367081&partnerID=MN8TOARS

By: R. Melchert, S. Belcher & R. Kennedy

Contributors: R. Melchert, S. Belcher & R. Kennedy

Source: ORCID
Added: March 5, 2021

2008 journal article

Rapid signaling mechanisms of estrogens in the developing cerebellum

Brain Research Reviews, 57(2), 481–492.

By: S. Belcher*

Contributors: S. Belcher*

author keywords: cerebellum; development; ERK; estrogen; non-genomic; signal transduction
MeSH headings : Animals; Brain Neoplasms / metabolism; Cerebellum / embryology; Cerebellum / metabolism; Child; Estrogens / metabolism; Humans; Receptors, Estrogen / metabolism; Signal Transduction / physiology
TL;DR: The goal of this review is to develop a contextual framework to understand the generalized function of estrogen during development of brain regions not known to be sexually specialized by building this framework on the more well-developed foundation of estrogen's gonad-driven sex-specific actions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: January 21, 2021

2008 journal article

Speciation analysis of arsenic in biological matrices by automated hydride generation-cryotrapping-atomic absorption spectrometry with multiple microflame quartz tube atomizer (multiatomizer)

J. Anal. At. Spectrom., 23(3), 342–351.

By: A. Hernández-Zavala*, T. Matoušek*, Z. Drobná*, D. Paul*, F. Walton*, B. Adair*, J. Dědina*, D. Thomas*, M. Stýblo*

TL;DR: The automated HG-CT-AAS system provides an effective and sensitive tool for analysis of all major human metabolites of iAs in complex biological matrices and the capacity to detect methylated As(III)- and As(V)-species was verified. (via Semantic Scholar)
Source: Crossref
Added: January 21, 2021

2008 journal article

Oxidation state specific generation of arsines from methylated arsenicals based on l-cysteine treatment in buffered media for speciation analysis by hydride generation-automated cryotrapping-gas chromatography-atomic absorption spectrometry with the multiatomizer

Spectrochimica Acta Part B: Atomic Spectroscopy, 63(3), 396–406.

author keywords: speciation analysis; arsenic; hydride generation atomic absorption spectrometry; cryotrapping; multiatornizer
TL;DR: This method permits a high-throughput speciation analysis of metabolites of inorganic arsenic in relatively complex biological matrices such as cell culture systems without sample pretreatment, thus preserving the distribution of tri- and pentavalent species. (via Semantic Scholar)
Source: Crossref
Added: January 21, 2021

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