Works Published in 2012
Displaying works 1 - 20 of 260 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Characterization of Novel Phages Isolated in Coagulase-Negative Staphylococci Reveals Evolutionary Relationships with Staphylococcus aureus Phages
Journal of Bacteriology, 194(21), 5829–5839.
jb.asm.org (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: April 4, 2024
2012 journal article
The Adaptation of Temperate Bacteriophages to Their Host Genomes
Molecular Biology and Evolution, 30(4), 737–751.
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: April 4, 2024
2012 journal article
The Impact of Student-Directed Research at an Undergraduate Liberal Arts Institution
Council on Undergraduate Research Quarterly, 33, 22–27.
Source: ORCID
Added: April 3, 2024
2012 journal article
Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus.
40(18), 8917–8926.
MeSH headings : Alleles; Animals; DNA Methylation; Genetic Loci; Genomic Imprinting; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Nuclear Proteins; Polyadenylation; Protein Isoforms / genetics; Protein Isoforms / metabolism; RNA, Messenger / metabolism; Transcription, Genetic; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism
TL;DR:
Changes in DNA methylation on the maternal allele at the Nap1l5 promoter increases the use of an internal Herc3 polyadenylation site and alters exon splicing, which demonstrate the influence of epigenetic mechanisms in regulating HerC3 alternative mRNA processing.
(via Semantic Scholar)
Source: ORCID
Added: September 28, 2022
2012 journal article
Thermal Tolerances of Freshwater Mussels and their Host Fishes: Species Interactions in a Changing Climate
Freshwater Mollusk Biology and Conservation, 15(1), 69.
TL;DR:
The findings in this meta-analysis suggest that thermal effects of anthropogenic landscape alteration and climate change may be compounded for freshwater mussels via their obligate life cycle interaction with fish and highlight the importance of considering global change effects in a community context.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 16, 2022
2012 journal article
Genotoxic Response of Unionid Mussel Hemolymph to Hydrogen Peroxide and Polycyclic Aromatic Hydrocarbons
Freshwater Mollusk Biology and Conservation, 15(2), 113.
TL;DR:
Assessment of the applicability of the comet assay in unionid mussel hemolymph sampled non-lethally with a reference genotoxicant, hydrogen peroxide (H2O2) and polycyclic aromatic hydrocarbons (PAHs) indicated that additional research and evaluation may be necessary before implementing the widespread use of a non-lethal, unionid Mussel hemlymph based genotoxicity screening tool for environmental biomonitoring.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 16, 2022
2012 book
Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors
In OECD Series on Testing and Assessment.
Sources: Crossref, NC State University Libraries
Added: September 15, 2022
2012 journal article
Analysis of T-DNA alleles of flavonoid biosynthesis genes in Arabidopsis ecotype Columbia
BMC Research Notes, 5(1).
MeSH headings : Acyltransferases / genetics; Acyltransferases / metabolism; Alleles; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Biosynthetic Pathways / genetics; Chromatography, High Pressure Liquid / methods; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; DNA, Bacterial / genetics; Ecotype; Flavonoids / biosynthesis; Flavonols / metabolism; Intramolecular Lyases / genetics; Intramolecular Lyases / metabolism; Mixed Function Oxygenases / genetics; Mixed Function Oxygenases / metabolism; Mutagenesis, Insertional; NADH, NADPH Oxidoreductases / genetics; NADH, NADPH Oxidoreductases / metabolism; Oxygenases / genetics; Oxygenases / metabolism; Pigmentation / genetics; Plants, Genetically Modified; Seeds / genetics; Seeds / metabolism
TL;DR:
An analysis of Arabidopsis lines of ecotype Columbia carrying T-DNA insertions in genes encoding enzymes of the central flavonoid pathway provides a comprehensive summary of various mutant alleles for these structural genes that have been described in the literature to date.
(via Semantic Scholar)
Source: ORCID
Added: January 30, 2022
2012 journal article
DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells.
Cancer Research.
MeSH headings : Animals; Cell Death / genetics; Cell Line; Cell Transformation, Neoplastic / genetics; Circadian Rhythm / genetics; Cryptochromes / genetics; Cryptochromes / physiology; DNA Damage; DNA-Binding Proteins / genetics; Doxorubicin / toxicity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagens / toxicity; Mutation; Nuclear Proteins / genetics; Organoplatinum Compounds / toxicity; Oxaliplatin; Tumor Protein p73; Tumor Suppressor Proteins / genetics; Ultraviolet Rays / adverse effects
TL;DR:
These findings establish distinct roles for cryptochromes in intrinsic apoptosis induced by UV mimetic and radiomimetic agents and Ras-transformed p53- and Cry-null mouse skin fibroblasts are more sensitive than p53 mutants to apoptotic cell death initiated by agents that activate either the intrinsic or the extrinsic apoptosis pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 24, 2021
2012 journal article
Effect of circadian clock mutations on DNA damage response in mammalian cells.
Cell Cycle (Georgetown, Tex.).
Contributors: S. Gaddameedhi* , J. Reardon*, R. Ye, N. Ozturk * & A. Sancar *
author keywords: Cryptochrome; Period; Clock; BMal1; DNA repair; checkpoint; apoptosis
MeSH headings : Animals; Apoptosis / drug effects; Apoptosis / genetics; Apoptosis / radiation effects; Ataxia Telangiectasia Mutated Proteins; CLOCK Proteins / genetics; CLOCK Proteins / metabolism; Cell Cycle Checkpoints / drug effects; Cell Cycle Checkpoints / genetics; Cell Cycle Proteins / metabolism; Cell Line; Cell Survival / drug effects; Cell Survival / genetics; Cell Survival / radiation effects; Checkpoint Kinase 2; Circadian Clocks / drug effects; Circadian Clocks / genetics; Circadian Clocks / radiation effects; DNA Damage / genetics; DNA Repair / drug effects; DNA Repair / genetics; DNA Repair / radiation effects; DNA-Binding Proteins / metabolism; Down-Regulation / drug effects; Down-Regulation / genetics; Down-Regulation / radiation effects; Enzyme Activation / drug effects; Enzyme Activation / radiation effects; Feedback, Physiological / drug effects; Feedback, Physiological / radiation effects; Humans; Mammals / genetics; Mammals / physiology; Mice; Mitomycin / pharmacology; Mutation / genetics; Protein Serine-Threonine Kinases / metabolism; Radiation, Ionizing; Tumor Suppressor Proteins / metabolism; Ultraviolet Rays
TL;DR:
It is concluded that the majority of DNA damage response reactions are not controlled by the circadian clock or that, even if such a control exists at the organism level, it is supplanted by homeostatic control mechanisms at the cellular level in tissue culture.
(via Semantic Scholar)
Source: ORCID
Added: December 24, 2021
2012 journal article
Endocytosis by target cells: an essential means for perforin- and granzyme-mediated killing
Cellular and Molecular Immunology, 9(1), 5–6.
TL;DR:
Endocytosis by target cells: an essential means for perforin- and granzyme-mediated killing and its applications in apoptosis and cell reprograming.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: August 24, 2021
2012 journal article
The crosstalk between autophagy and apoptosis: where does this lead?
Protein & Cell, 3(1), 17–27.
author keywords: autophagy; apoptosis; Beclin-1; lymphocytes
MeSH headings : Animals; Apoptosis / physiology; Apoptosis Regulatory Proteins / metabolism; Autophagy / physiology; Humans; Neoplasms / metabolism; Neoplasms / pathology; Neoplasms / therapy; Proteolysis; Signal Transduction
TL;DR:
Investigation of the interactions between Beclin-1 and Bcl-2/Bcl-xL and between FADD and Atg5, caspase- and calpain-mediated cleavage of autophagy-related proteins, and autophagic degradation of caspases is necessary to elucidate the mechanisms controlling the balance between survival and death both under normal conditions and in diseases including cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 24, 2021
2012 report
Detailed review paper on the state of the science on novel in vitro and in vivo screening and testing methods and endpoints for evaluating endocrine disruptors
(Series on Testing & Assessment No. 178). Organization for Economic Co-operation and Development.
Source: NC State University Libraries
Added: August 8, 2021
2012 thesis
A Bayesian Hierarchical Spatial Model for West Nile Virus in New York City: Evaluating an Approach to Handle Large Spatial Data Sets
(M.S. Thesis). University of Georgia, Athens, Georgia.
Source: NC State University Libraries
Added: April 24, 2021
2012 journal article
Assessing Accumulation and Sublethal Effects of Lead in a Unionid Mussel
Freshwater Mollusk Biology and Conservation, 15(1), 60.
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: March 26, 2021
2012 conference paper
A Studio Lab for the Undergraduate Biology Curriculum: Using a Comparative Endocrinology Model to Recruit Future Scientists
Integrative and Comparative Biology, 52(Suppl 1), 260.
Event: Society for Integrative and Comparative Biology Annual Meeting at Charleston, SC on January 3-7, 2012
Source: NC State University Libraries
Added: March 26, 2021
2012 chapter
Ecological Risk Assessment
In E. Hodgson (Ed.), Toxicology and Human Environments (pp. 323–348). London: Academic Press.
Ed(s): E. Hodgson
Source: NC State University Libraries
Added: March 26, 2021
2012 journal article
Assessment of Polycyclic Aromatic Hydrocarbon Contamination of Breeding Pools Utilized by the Puerto Rican Crested Toad, Peltophryne lemur
International Scholarly Research Notices, 2012, 309853.
TL;DR:
Bioavailable water concentrations of Polycyclic Aromatic Hydrocarbon contaminants within breeding pools at 3 sites were established using Passive Sampling Devices (PSDs) and gas chromatography-mass spectrometry (GC/MS).
(via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: March 18, 2021
2012 journal article
Estrogen-like disruptive effects of dietary exposure to bisphenol A or 17α-ethinyl estradiol in CD1 mice
International Journal of Toxicology, 31(6), 537–550.
Contributors: E. Kendig*, D. Buesing*, S. Christie*, C. Cookman*, R. Gear*, E. Hugo*, S. Kasper*, J. Kendziorski*
author keywords: Bisphenol A; diabetes; endocrine disruptor; estrogen; metabolic effects; obesity; prolactin
MeSH headings : Animal Feed; Animals; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Environmental Pollutants / toxicity; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Female; Glucose Tolerance Test; Male; Maternal Exposure; Mice; Mice, Inbred Strains; No-Observed-Adverse-Effect Level; Obesity / chemically induced; Organ Size / drug effects; Paternal Exposure; Phenols / toxicity; Reproduction / drug effects; Sex Factors; Sexual Maturation / drug effects; Sperm Count; Spermatozoa / drug effects; Uterus / drug effects
TL;DR:
Overall, BPA was found to have modest, sex specific endocrine disruptive effects on a variety of end points below the established no observed adverse effect level, and the dose response characteristics for many of the effects were nonmonotonic and not predictable from high-dose extrapolations.
(via Semantic Scholar)
Source: ORCID
Added: March 5, 2021
2012 journal article
Rapid estrogen receptor-mediated mechanisms determine the sexually dimorphic sensitivity of ventricular myocytes to 17β-estradiol and the environmental endocrine disruptor bispheno A
Endocrinology, 153(2), 712–720.
Contributors: S. Belcher* , Y. Chen *, S. Yan * & H. Wang *
MeSH headings : Animals; Benzhydryl Compounds; Calcium / metabolism; Calcium Signaling / physiology; Cells, Cultured; Dose-Response Relationship, Drug; Endocrine Disruptors / pharmacology; Estradiol / administration & dosage; Estradiol / pharmacology; Female; Male; Mice; Mice, Knockout; Myocardial Contraction / drug effects; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / physiology; Phenols / administration & dosage; Phenols / pharmacology; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Sex Characteristics
TL;DR:
The sex-specific sensitivity of myocytes to estrogens and the rapid arrhythmogenic effects of BPA and estradiol in the female heart are regulated by the balance between ERα and ERβ signaling.
(via Semantic Scholar)
Source: ORCID
Added: March 5, 2021
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