Works Published in 2012
Displaying works 301 - 310 of 310 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Graph fission in an evolving voter model
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(10), 3682–3687.
author keywords: coevolutionary network; quasi-stationary distribution; Wright-Fisher diffusion; approximate master equation
MeSH headings : Algorithms; Computer Simulation; Diffusion; Humans; Models, Statistical; Models, Theoretical; Politics; Probability; Public Opinion; Social Support
TL;DR:
Using simulations and approximate calculations, it is explained why these two nearly identical models of a social network in which individuals have one of two opinions and their opinions and the network connections coevolve have such dramatically different phase transitions.
(via Semantic Scholar)
www.pnas.org (publisher PDF)
UN Sustainable Development Goal Categories
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2012 journal article
Enhanced activity of an insecticidal protein, trypsin modulating oostatic factor (TMOF), through conjugation with aliphatic polyethylene glycol
PEST MANAGEMENT SCIENCE, 68(1), 49–59.
author keywords: trypsin modulating oostatic factor; TMOF; PEGylation; polyethylene glycol; mosquito; tobacco budworm; cotton bollworm; protein delivery
MeSH headings : Aedes / drug effects; Aedes / growth & development; Animals; Insecticides / chemical synthesis; Insecticides / chemistry; Insecticides / pharmacology; Larva / drug effects; Larva / growth & development; Moths / drug effects; Oligopeptides / chemistry; Oligopeptides / pharmacology; Polyethylene Glycols / chemistry
TL;DR:
Aliphatic PEG polymers can be used as a new method for increasing the activity of insecticidal proteins, according to research suggests.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 review
Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems
[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 24(1), 144–159.
author keywords: xenoestrogens; dichloro diphenyl trichloroethane; methoxychlor; biocides; tributyltin; bisphenol A; diethylstilbestrol; ethinylestradiol; phytoestrogens; aryl hydrocarbon receptor; the peroxisome proliferator-activated receptor; retinoid X receptor
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds; Brain / drug effects; Endocrine Disruptors / pharmacology; Environmental Pollutants / pharmacology; Humans; Phenols / pharmacology; Phytoestrogens / pharmacology; Puberty / drug effects; Reproduction / drug effects
TL;DR:
EDCs, from varied sources, may have organisational effects during development and/or activational effects in adulthood that influence sexually‐dimorphic, reproductively‐relevant processes or other functions, by mimicking, antagonising or altering steroidal actions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
S-Layer Homology Domain Proteins Csac_0678 and Csac_2722 Are Implicated in Plant Polysaccharide Deconstruction by the Extremely Thermophilic Bacterium Caldicellulosiruptor saccharolyticus
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 78(3), 768–777.
MeSH headings : Enzyme Stability; Glycoside Hydrolases / chemistry; Glycoside Hydrolases / genetics; Glycoside Hydrolases / metabolism; Gram-Positive Bacteria / enzymology; Gram-Positive Bacteria / genetics; Gram-Positive Bacteria / metabolism; Hydrogen-Ion Concentration; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Molecular Weight; Open Reading Frames; Plants / microbiology; Polysaccharides / metabolism; Protein Binding; Sequence Deletion; Temperature
TL;DR:
Roles for Csac-0678 and Csac_2722 in recruitment and hydrolysis of complex polysaccharides and the deconstruction of lignocellulosic biomass are indicated and related SLH domain proteins in other Caldicellulosiruptor genomes may also be important contributors to plant biomass utilization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 journal article
Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer
CANCER BIOLOGY & THERAPY, 13(3), 130–137.
author keywords: colon cancer; EGFR; calcium; mouse models; AG1478; therapy; toxicity
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Antineoplastic Agents / toxicity; Azoxymethane; Calcium / pharmacology; Calcium / therapeutic use; Calcium / toxicity; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Colonic Neoplasms / chemically induced; Colonic Neoplasms / drug therapy; Colonic Neoplasms / pathology; Dietary Supplements; Drug Screening Assays, Antitumor; Drug Synergism; ErbB Receptors / antagonists & inhibitors; Female; Humans; MAP Kinase Signaling System / drug effects; Male; Mice; Mice, Inbred C57BL; Quinazolines / pharmacology; Quinazolines / therapeutic use; Quinazolines / toxicity; Random Allocation; Tumor Burden / drug effects; Tyrphostins / pharmacology; Tyrphostins / therapeutic use; Tyrphostins / toxicity
TL;DR:
Calcium supplementation combined with pharmacologic blockade of EGFR results in an additive effect on tumor growth inhibition in all models and the combined use of dietary calcium supplementation and EGFR inhibitors also resulted in elevated toxicity suggesting that careful consideration be given when combining dietary supplements with prescribed cancer therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Association genetics of the loblolly pine (Pinus taeda, Pinaceae) metabolome
NEW PHYTOLOGIST, 193(4), 890–902.
author keywords: association genetics; forest trees; loblolly pine (Pinus taeda); metabolome; natural selection; single nucleotide polymorphisms (SNPs)
MeSH headings : Bayes Theorem; Gene Frequency; Genetic Association Studies; Genetics, Population; Metabolome; Models, Genetic; Pinus taeda / genetics; Pinus taeda / metabolism; Polymorphism, Single Nucleotide; Southeastern United States
TL;DR:
Standard association genetic methods are used to correlate 3563 single nucleotide polymorphisms (SNPs) to concentrations of 292 metabolites measured in a single loblolly pine (Pinus taeda) association population, highlighting the importance of multi-SNP models to association mapping and the implications for association mapping in forest trees.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Strong influence of regional species pools on continent-wide structuring of local communities
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 279(1727), 266–274.
Contributors: J. Lessard *, M. Borregaard *, J. Fordyce *, C. Rahbek *, M. Weiser n, R. Dunn n , N. Sanders *
author keywords: regional species pool; community assembly; phylogenetics; tropical niche conservatism; diversity gradients; Formicidae
MeSH headings : Animals; Ants / physiology; Biodiversity; Climate; North America; Phylogeny; Population Dynamics; Temperature
TL;DR:
It is found that the average phylogenetic relatedness of species in ant communities decreases from tropical to temperate regions, but the strength of this relationship depends on the level of ecological realism in the definition of source pools.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 article
On the scent of pleiotropy
Singh, N. D., & Shaw, K. L. (2012, January 3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 109, pp. 5–6.
MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / enzymology; Drosophila melanogaster / genetics; Fatty Acid Desaturases / genetics; Female; Gene Expression Regulation, Enzymologic; Male; Nervous System / enzymology; Perception / physiology; Sex Attractants / metabolism
TL;DR:
The work presented in PNAS by Bousquet et al. (4) builds the best case to date for genetic coupling between signaler and receiver traits in sexual communication.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Genetic Architecture of Maize Kernel Composition in the Nested Association Mapping and Inbred Association Panels
PLANT PHYSIOLOGY, 158(2), 824–834.
Contributors: J. Cook n, M. McMullen n, J. Holland n , F. Tian n, P. Bradbury n, J. Ross-Ibarra n, E. Buckler n, S. Flint-Garcia n
MeSH headings : Genes, Plant; Genetic Linkage; Genome-Wide Association Study; Quantitative Trait Loci; Zea mays / genetics
TL;DR:
Joint-linkage quantitative trait locus mapping and genome-wide association studies for kernel starch, protein, and oil in the maize nested association mapping population, composed of 25 recombinant inbred line families derived from diverse inbred lines, revealed that the genetic architecture of kernel composition traits is controlled by 21–26 quantitative traits loci.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Conformational Changes in Sindbis Virus Induced by Decreased pH Are Revealed by Small-Angle Neutron Scattering
JOURNAL OF VIROLOGY, 86(4), 1982–1987.
MeSH headings : Hydrogen-Ion Concentration; RNA, Viral / chemistry; RNA, Viral / genetics; RNA, Viral / metabolism; Scattering, Small Angle; Sindbis Virus / chemistry; Sindbis Virus / genetics; Sindbis Virus / metabolism; Viral Proteins / chemistry; Viral Proteins / genetics; Virion / chemistry; Virion / genetics; Virion / metabolism
TL;DR:
Small-angle neutron scattering with contrast variation is employed to probe how the structure of a mammalian-grown Sindbis virus responds to moderately acidic pH and improves the understanding of the pH-driven alteration of Sind Bis virus structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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