Works Published in 2014
Displaying all 8 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Sampling and summary statistics of endpoint-conditioned paths in DNA sequence evolution
Bayesian Phylogenetics: Methods, Algorithms, and Applications, 247–275.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Structural properties of the minimum cut of partially-supplied graphs
DISCRETE APPLIED MATHEMATICS, 177, 152–157.
author keywords: Graph theory; Minimum cut; Tree reconstruction
TL;DR:
This work considers pairs of graphs G and H, with respective Laplacian matrices L and M, and calls H partially supplied provided M is a Schur complement of L.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 personal communication
Predictor performance with stratified data and imbalanced classes
Stone, E. A. (2014, August).
MeSH headings : Evolution, Molecular; Exome / genetics; Genetic Variation / genetics; HapMap Project; High-Throughput Nucleotide Sequencing; Humans
TL;DR:
The results provide strong evidence that machine-learning classifiers must incorporate all known biological knowledge and embrace differences in the level of functional importance of positions when assembling training and testing datasets and invalidate Vihinen's conclusion that the accuracy of the prediction of ultraconserved and lessconserved sites are lower.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
No Evidence for a Global Male-Specific Lethal Complex-Mediated Dosage Compensation Contribution to the Demasculinization of the Drosophila melanogaster X Chromosome
PLOS ONE, 9(8).
MeSH headings : Animals; Chromosomal Proteins, Non-Histone / metabolism; Chromosome Mapping; Chromosomes, Insect / physiology; DNA Helicases / metabolism; DNA-Binding Proteins / metabolism; Dosage Compensation, Genetic / genetics; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Genes, X-Linked / physiology; Histone Acetyltransferases / metabolism; Male; Multiprotein Complexes / metabolism; Multiprotein Complexes / physiology; Nuclear Proteins / metabolism; Sex Differentiation / genetics; Transcription Factors / metabolism; Transcriptional Activation; X Chromosome / physiology
TL;DR:
The results do not corroborate previous observations supporting organismal-wide detrimental effects by dosage compensation on X-linked male-biased expressed genes and find no evidence that dosage compensation has played a role in the arrangement of dosage compensated male- biased genes on the X chromosome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits
NATURE COMMUNICATIONS, 5.
MeSH headings : Aging / physiology; Animals; Drosophila melanogaster / genetics; Female; Fertility / genetics; Gene Ontology; Genetic Fitness / genetics; Genome-Wide Association Study; Male; Mutation; Polymorphism, Single Nucleotide
TL;DR:
The authors identify genetic variants in Drosophilathat that affect reproduction and lifespan in an age-specific manner, and provide support for the mutation accumulation theory of aging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Cyclic Tensile Strain Enhances Osteogenesis and Angiogenesis in Mesenchymal Stem Cells from Osteoporotic Donors
TISSUE ENGINEERING PART A, 20(1-2), 67–78.
MeSH headings : Aged, 80 and over; Calcium / metabolism; Cell Differentiation; Cell Proliferation; Cell Separation; Female; Gene Expression Regulation; Gene Regulatory Networks; Humans; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Neovascularization, Physiologic / genetics; Oligonucleotide Array Sequence Analysis; Osteogenesis / genetics; Osteoporosis, Postmenopausal / genetics; Osteoporosis, Postmenopausal / pathology; Proto-Oncogene Mas; Real-Time Polymerase Chain Reaction; Signal Transduction / genetics; Stress, Mechanical; Tensile Strength; Tissue Donors; White People
TL;DR:
It is demonstrated that hMSC from aged, osteoporotic donors are capable of enhanced osteogenic differentiation in response to 10% cyclic tensile strain with significant increases in the expression of genes associated with enhanced cell proliferation, musculoskeletal development, and angiogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
Genome Research, 24(7), 1193–1208.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Population Genomic Analysis Reveals No Evidence for GC-Biased Gene Conversion in Drosophila melanogaster
MOLECULAR BIOLOGY AND EVOLUTION, 31(2), 425–433.
author keywords: GC-biased gene conversion; Drosophila melanogaster; whole genome; polymorphism and divergence data
MeSH headings : Alleles; Animals; Chromosomes, Insect; Cytosine / metabolism; Drosophila melanogaster / genetics; Evolution, Molecular; Gene Conversion; Genome, Insect; Genomics; Guanine / metabolism; Mutation Rate; Phylogeny; Polymorphism, Genetic
TL;DR:
It is suggested that this process of gene conversion in Drosophila melanogaster is unlikely to significantly contribute to patterns of polymorphism and divergence in this system, and the results provide no support for GC-biased gene conversion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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