Works Published in 2021
Displaying all 12 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 journal article
Periconceptional Maternal Diet Characterized by High Glycemic Loading Is Associated with Offspring Behavior in NEST
Nutrients, 13(9), 3180.
MeSH headings : Child Behavior Disorders / etiology; DNA Methylation; Dental Anxiety / etiology; Diet / adverse effects; Dietary Carbohydrates / adverse effects; Female; Glycemic Load / physiology; Humans; Impulsive Behavior; Infant; Infant Behavior; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects / metabolism; Sex Factors; Temperament
TL;DR:
Findings highlight the importance of maternal dietary patterns on offspring neurodevelopment, offering avenues for prevention options for mothers.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: ORCID
Added: April 11, 2023
2021 journal article
Lrp1 regulation of pulmonary function follow-up of human GWAS in mice
American Journal of Respiratory Cell and Molecular Biology, 64(3), 368–378.
Contributors: C. Nichols*, J. House* , H. Li *, J. Ward, A. Wyss, J. Williams *, L. Deterding *, J. Bradbury*
MeSH headings : Animals; Bronchoalveolar Lavage Fluid; Genome-Wide Association Study; Humans; Lipopolysaccharides / pharmacology; Low Density Lipoprotein Receptor-Related Protein-1 / metabolism; Lung / physiology; Mice; Muscle, Smooth / drug effects; Muscle, Smooth / metabolism; Polymorphism, Single Nucleotide / genetics; Proteome / metabolism; Pyroglyphidae / physiology; Quantitative Trait Loci / genetics
TL;DR:
Investigation of the effect of genetic disruption of the Lrp1 gene in smooth muscle cells on pulmonary function in naïve animals and after exposure to bacterial lipopolysaccharide (LPS) or house dust mite extract (HDME) suggests dysregulation of LRP1 in smoother muscle cells affects baseline pulmonary function and airway responsiveness.
(via Semantic Scholar)
Source: ORCID
Added: April 11, 2023
2021 article
Glucose dynamics during ozone exposure measured using radiotelemetry: Stress drivers
Henriquez, A. R., Snow, S. J., Jackson, T. W., House, J. S., Motsinger-Reif, A. A., Ward-Caviness, C. K., … Kodavanti, U. P. (2021, December 9). (Vol. 12). Vol. 12.
TL;DR:
The temporality of neuroendocrine-stress-mediated biological sequalae responsible for ozone-induced metabolic dysfunction as exposure occurs is demonstrated for the first time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: April 11, 2023
2021 journal article
Peripheral metabolic effects of ozone exposure in healthy and diabetic rats on normal or high-cholesterol diet
Toxicology and Applied Pharmacology, 415, 115427.
Contributors: S. Snow *, A. Henriquez *, A. Fisher*, B. Vallanat*, J. House* , M. Schladweiler *, C. Wood*, U. Kodavanti *
MeSH headings : Adipose Tissue, White / drug effects; Adipose Tissue, White / metabolism; Adipose Tissue, White / pathology; Air Pollutants / toxicity; Animals; Biomarkers / blood; Blood Glucose / drug effects; Blood Glucose / metabolism; Body Composition / drug effects; Cholesterol, Dietary / metabolism; Cholesterol, Dietary / toxicity; Diabetes Mellitus, Type 2 / blood; Diabetes Mellitus, Type 2 / complications; Diabetes Mellitus, Type 2 / genetics; Diet, High-Fat / adverse effects; Disease Models, Animal; Energy Metabolism / drug effects; Gene Expression Regulation; Inhalation Exposure; Insulin / blood; Lipids / blood; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Ozone / toxicity; Rats, Wistar; Species Specificity
TL;DR:
Findings indicate that peripheral metabolic alterations induced by diabetes and high-cholesterol diet can enhance susceptibility to the metabolic effects of inhaled pollutants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: April 11, 2023
2021 journal article
The Role of Hepatic Vagal Tone in Ozone-Induced Metabolic Dysfunction in the Liver
Toxicological Sciences, 181(2), 229–245.
Contributors: C. Colonna*, A. Henriquez *, J. House* , A. Motsinger-Reif *, D. Alewel *, A. Fisher*, H. Ren*, S. Snow *
MeSH headings : Air Pollutants / toxicity; Animals; Liver; Male; Ozone / toxicity; Rats; Rats, Inbred WKY; Transcriptome
TL;DR:
Parasympathetic innervation modulated ozone-induced liver transcriptional responses for cell growth and regeneration without affecting stress-mediated metabolic changes, which could collectively contribute to adverse effects of air pollutants on the liver.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: April 11, 2023
2021 journal article
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs
PLOS GENETICS, 17(8).
Ed(s): F. Vazquez
MeSH headings : Antineoplastic Agents / pharmacology; Biomarkers, Pharmacological / analysis; Cell Line, Tumor; Genome-Wide Association Study / methods; High-Throughput Screening Assays / methods; Humans; NAD(P)H Dehydrogenase (Quinone) / drug effects; NAD(P)H Dehydrogenase (Quinone) / genetics; NAD(P)H Dehydrogenase (Quinone) / metabolism
TL;DR:
The NAD(P)H quinone dehydrogenase 1 (NQO1) gene was found to be associated with the dose-response of arsenic trioxide, erlotinib, tramet inib, and a combination treatment of paclitaxel + epirubicin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 14, 2022
2021 journal article
Genome and transcriptome sequencing of the green bottle fly, Lucilia sericata, reveals underlying factors of sheep flystrike and maggot debridement therapy
GENOMICS, 113(6), 3978–3988.
author keywords: Lucilia sericata; Maggot debridement therapy; Whole genome; Salivary gland; Malpighian tubule; Heat shock
MeSH headings : Animals; Calliphoridae; Debridement; Diptera / genetics; Humans; Larva / genetics; Larva / metabolism; Sheep / genetics; Transcriptome
TL;DR:
The assembly of a 565.3 Mb genome from long read PacBio DNA sequencing of genomic DNA is reported, which will underpin future genetic studies and in development of engineered strains for genetic control of L. sericata and for biotechnology-enhanced maggot therapy.
(via Semantic Scholar)
Source: Web Of Science
Added: October 26, 2021
2021 journal article
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome‐Wide Interaction Meta‐Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies
Clinical Pharmacology & Therapeutics, 110(3), 723–732.
MeSH headings : Black or African American / genetics; Aged; Antihypertensive Agents / therapeutic use; Blood Pressure / drug effects; Blood Pressure / genetics; Cardiovascular Diseases / chemically induced; Cardiovascular Diseases / genetics; Cardiovascular System / drug effects; Drug-Related Side Effects and Adverse Reactions / etiology; Drug-Related Side Effects and Adverse Reactions / genetics; Female; Genome-Wide Association Study / methods; Humans; Hypertension / drug therapy; Hypertension / genetics; Male; Middle Aged; Pharmacogenomic Testing / methods; Polymorphism, Single Nucleotide / genetics
TL;DR:
The NTM region is associated with increased risk for adverse cardiovascular outcomes and less BP reduction in β-blocker treated patients and no SNPs attained genome-wide significance for any other drugs classes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: August 23, 2021
2021 article
High-resolution characterization of the structural features and genetic variation of six feline leukocyte antigen class I loci via single molecule, real-time (SMRT) sequencing
Holmes, J. C., Scholl, E. H., Dickey, A. N., & Hess, P. R. (2021, June 27). IMMUNOGENETICS.
author keywords: Cats; Class I genes; High-throughput DNA sequencing; Major histocompatibility complex; Polymorphism
MeSH headings : Animals; Cats; Exons; Genes, MHC Class I / genetics; Genetic Variation; Haplotypes; High-Throughput Nucleotide Sequencing; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Sequence Analysis, DNA / methods
TL;DR:
A targeted approach to FLAI genotyping, using the single-molecule real-time (SMRT) platform, which allows full-length (3.4-kb) reads without assembly, is developed, which could allow highly accurate allele surveys in large cat cohorts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 6, 2021
2021 personal communication
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning
Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).
Contributors: S. Marvel n, J. House* , M. Wheeler *, K. Song n, Y. Zhou n , F. Wright n, W. Chiu *, I. Rusyn *, A. Motsinger-Reif*, D. Reif n
MeSH headings : COVID-19 / epidemiology; Data Visualization; Health Status Indicators; Humans; Machine Learning; Models, Statistical; Vulnerable Populations
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 22, 2021
2021 journal article
Grouping of UVCB Substances with New Approach Methodologies (NAMs) Data
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 38(1), 123–137.
Contributors: J. House n , F. Grimm*, W. Klaren*, A. Dalzell*, S. Kuchi*, S. Zhang *, K. Lenz*, P. Boogaard *
MeSH headings : Animal Testing Alternatives / methods; Hazardous Substances / chemistry; Hazardous Substances / toxicity; Humans; Induced Pluripotent Stem Cells / drug effects; Petroleum / analysis; Petroleum / toxicity; Toxicity Tests / methods
TL;DR:
It is demonstrated that in vitro test-derived biological activity signatures, including bioactivity from human induced pluripotent stem cell and primary cells, can be used to inform groupings of UVCBs, to assist in identification of representative substances in each group for testing when needed, and to fill data gaps by read-across.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 15, 2021
2021 journal article
Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort
PEDIATRIC OBESITY, 16(7).
Contributors: R. Maguire n, J. House n , D. Lloyd n, H. Skinner n, T. Allen *, A. Raffi n, D. Skaar n, S. Park n
author keywords: cytokines; maternal obesity; childhood obesity
MeSH headings : Black or African American; Body Mass Index; Child; Child, Preschool; Cohort Studies; Cytokines / blood; Female; Humans; Obesity, Maternal / epidemiology; Pediatric Obesity / epidemiology; Pregnancy; White People
TL;DR:
Although maternal systemic inflammation is hypothesized to link maternal pre‐pregnancy obesity to offspring metabolic dysfunction, patient empirical data are limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
