Works Published in 2004

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2004 chapter

Introduction to Biochemical and Molecular Methods in Toxicology

In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 13–22).

By: E. Hodgson n, G. Leblanc n, S. Meyer* & R. Smart n

Ed(s): E. Hodgson n

Sources: Crossref, ORCID
Added: April 10, 2022

2004 chapter

Chemical Carcinogenesis

In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 225–250).

By: R. Smart n

Ed(s): E. Hodgson

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: April 9, 2022

2004 journal article

C/EBP alpha is a DNA damage-inducible p53-regulated mediator of the G(1) checkpoint in keratinocytes

MOLECULAR AND CELLULAR BIOLOGY, 24(24), 10650–10660.

By: K. Yoon n & R. Smart n

MeSH headings : Animals; Blotting, Western; CCAAT-Enhancer-Binding Protein-alpha / metabolism; Caspases / analysis; Cell Line; Cells, Cultured; DNA Damage; Dose-Response Relationship, Radiation; Electrophoretic Mobility Shift Assay; Fibroblasts / drug effects; Fibroblasts / metabolism; Fibroblasts / radiation effects; G1 Phase; Humans; Immunohistochemistry; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Keratinocytes / radiation effects; Kinetics; Methylnitronitrosoguanidine / pharmacology; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mutagens / pharmacology; NIH 3T3 Cells; Precipitin Tests; Rats; Retroviridae / genetics; Skin / metabolism; Time Factors; Tumor Suppressor Protein p53 / deficiency; Tumor Suppressor Protein p53 / metabolism; Ultraviolet Rays
TL;DR: A novel role is uncovered for C/EBPα as a p53-regulated DNA damage-inducible gene that has a critical function in the DNA damage G1 checkpoint response in keratinocytes. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Cell cycle-dependent phosphorylation of C/EBP beta mediates oncogenic cooperativity between C/EBP beta and H-Ras(V12)

MOLECULAR AND CELLULAR BIOLOGY, 24(17), 7380–7391.

By: J. Shuman*, T. Sebastian*, P. Kaldis*, T. Copeland*, S. Zhu n, R. Smart n, P. Johnson*

MeSH headings : Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Protein-beta / genetics; CCAAT-Enhancer-Binding Protein-beta / metabolism; CDC2-CDC28 Kinases / metabolism; Cell Cycle / physiology; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Enzyme Inhibitors / metabolism; Genes, ras; Mice; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; Molecular Sequence Data; NIH 3T3 Cells; Phosphorylation; Proto-Oncogene Proteins c-raf / genetics; Proto-Oncogene Proteins c-raf / metabolism; Sequence Alignment; Serine / metabolism; Signal Transduction; Threonine / metabolism; ras Proteins / genetics; ras Proteins / metabolism
TL;DR: It is shown that cell cycle-dependent phosphorylation of C/EBPβ on Ser64 and Thr189 is required to promote Ras-induced transformation of NIH 3T3 cells, and this support a role for C/ EBPβ as a nuclear effector of Ras signaling and transformation. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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