Environmental Health Science

Works Published in 2016

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Displaying all 13 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 journal article

Regulatory links between imprinted genes: evolutionary predictions and consequences.

By: M. Patten *, M. Cowley n , R. Oakey * & R. Feil *

author keywords: evolution; genomic imprinting; gene network; trans regulation
MeSH headings : Animals; Biological Evolution; Gene Regulatory Networks; Genomic Imprinting; Mammals / genetics
TL;DR: An evolutionary view of these trans-regulatory effects provides a novel interpretation of the logic of gene networks within species and has implications for the origin of reproductive isolation between species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: September 28, 2022

2016 journal article

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

The American Journal of Human Genetics, 98(4), 680–696.

By: B. Joubert *, J. Felix*, P. Yousefi *, K. Bakulski*, A. Just *, C. Breton *, S. Reese *, C. Markunas* ...

MeSH headings : Asthma / etiology; Asthma / genetics; Child; Child, Preschool; Chromosome Mapping; Cleft Lip / etiology; Cleft Lip / genetics; Cleft Palate / etiology; Cleft Palate / genetics; DNA Methylation; Epigenesis, Genetic; Female; Genetic Association Studies; Humans; Infant; Infant, Newborn; Pregnancy; Smoking / adverse effects; White People / genetics
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020

2016 article

Environmentally Induced Alterations in the Epigenome Affecting Obesity and Cancer in Minority Populations

EPIGENETICS, ENERGY BALANCE, AND CANCER, pp. 109–146.

By: D. Skaar n, R. Jirtle n & C. Hoyo n

author keywords: Obesity; Obesogen; Prostate cancer; Adenocarcinoma; Disparity; Epigenetic
TL;DR: Evidence for the influence of environmental exposures on obesity and how epigenetic alterations may contribute to cancers that disproportionately affect minority populations exhibit disparities in incidence and mortality are summarized in this chapter. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

An Automated Pipeline to Monitor System Performance in Liquid Chromatography-Tandem Mass Spectrometry Proteomic Experiments

JOURNAL OF PROTEOME RESEARCH, 15(12), 4763–4769.

By: M. Bereman*, J. Beri*, V. Sharma*, C. Nathe, J. Eckels, B. MacLean *, M. MacCoss *

author keywords: system suitability; process control; proteomics; tandem mass spectrometry; control charts
MeSH headings : Automation; Chromatography, Liquid / methods; Chromatography, Liquid / standards; Information Dissemination; Internet; Proteomics / methods; Tandem Mass Spectrometry / methods; Tandem Mass Spectrometry / standards; Workflow
TL;DR: The development of a completely automated pipeline to monitor system suitability in bottom-up proteomic experiments, termed Panorama AutoQC, is reported, to evaluate LC-MS/MS performance in a range of scenarios including identification of suboptimal instrument performance, evaluation of ultrahigh pressure chromatography, and identification of the major sources of variation throughout years of peptide data collection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Improving the analytical performance and versatility of paper spray mass spectrometry via paper microfluidics

ANALYST, 141(13), 4065–4073.

By: I. Murray n, G. Walker n & M. Bereman n

TL;DR: Two paper-based microfluidic techniques, photolithography and wax patterning, were investigated for their potential to improve upon the sensitivity, reproducibility, and versatility of paper spray mass spectrometry. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 article

Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype

TRANSLATIONAL TOXICOLOGY: DEFINING A NEW THERAPEUTIC DISCIPLINE, pp. 139–169.

By: D. Skaar n, S. Murphy* & C. Hoyo n

author keywords: Cadmium; Lead; Arsenic; Mercury; Epigenetics; DNA methylation; Cancer; Neurodevelopment
TL;DR: The extent to which heavy-metal-associated epigenetic alterations alter susceptibility to common chronic diseases and how they might be mitigated by some nutrients is discussed, albeit within narrow margins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study

Clinical Epigenetics, 8.

By: A. Soubry, L. Guo, Z. Huang, C. Hoyo, S. Romanus, T. Price, S. Murphy

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Maternal B vitamins: effects on offspring weight and DNA methylation at genomically imprinted domains

Clinical Epigenetics, 8.

By: L. McCullough, E. Miller, M. Mendez, A. Murtha, S. Murphy & C. Hoyo

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood

ENVIRONMENTAL HEALTH PERSPECTIVES, 124(5), 666–673.

By: Y. Li *, C. Xie *, S. Murphy *, D. Skaar n, M. Nye*, A. Vidal *, K. Cecil *, K. Dietrich* ...

MeSH headings : Cell Cycle Proteins / metabolism; Child Development / physiology; Child, Preschool; DNA Methylation; Environmental Exposure / statistics & numerical data; Environmental Pollutants / blood; Female; Humans; Infant; Infant, Newborn; Insulin-Like Growth Factor II / metabolism; Lead / blood; Male; Transcription Factors / metabolism; Tumor Suppressor Proteins / metabolism
TL;DR: Evidence is provided that early childhood lead exposure results in sex-dependent and gene-specific DNA methylation differences in the DMRs of PEG3, IGF2/H19, and PLAGL1/HYMAI in adulthood. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

DNA methylation in newborns and maternal smoking in pregnancy: Genome-wide consortium meta-analysis

American Journal of Human Genetics, 98(4), 680–696.

By: B. Joubert, J. Felix, P. Yousefi, K. Bakulski, A. Just, C. Breton, S. Reese, C. Markunas ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort

CHILDHOOD OBESITY, 12(3), 210–218.

By: B. Fuemmeler *, L. Wang *, E. Iversen *, R. Maguire n, S. Murphy * & C. Hoyo n

MeSH headings : Adult; Body Mass Index; Child Development; Child, Preschool; Epigenomics; Female; Humans; Hypertension, Pregnancy-Induced / epidemiology; Infant; Infant, Newborn; Male; Mothers; Obesity / epidemiology; Parity; Pregnancy; Pregnancy Complications / epidemiology; Risk Factors; Smoking / epidemiology; Southeastern United States / epidemiology; Time Factors; Weight Gain
TL;DR: The findings contribute new data on the associations between gestational weight gain and aspects of early growth using the SITAR method, and support a growing consensus in the literature that both prepregnancy BMI and gestations relate independently to risk for greater postnatal weight growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2016 review

Regulatory links between imprinted genes: Evolutionary predictions and consequences

By: M. Patten, M. Cowley , R. Oakey & R. Feil

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example

BIODEMOGRAPHY AND SOCIAL BIOLOGY, 62(1), 87–104.

By: K. King*, J. Kane*, P. Scarbrough*, C. Hoyo n & S. Murphy *

MeSH headings : Adult; DNA Methylation / physiology; Family Characteristics; Female; Humans; Marital Status; North Carolina; Pregnancy; Pregnant Women; RNA, Long Noncoding / genetics; Residence Characteristics / statistics & numerical data; Social Environment; Stress, Psychological; Young Adult
TL;DR: It is found that maternal social resources may result in differential methylation of MEG3, which demonstrates a potential partial mechanism priming socially disadvantaged newborns for later risk of some cancers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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