Works Published in 2017

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Displaying all 18 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

MP92-09 Implications of Regionalizing Care in the Developing World: Impact of Distance to Referral Center on Compliance to Biopsy Recommendations in a Brazilian Prostate Cancer Screening Cohort

Journal of Urology, 197(4S).

By: A. Freedland, C. Hoyo*, E. Turner, P. Moorman, R. Muller, E. Faria, G. Carvahal, R. Reis ...

TL;DR: GI and urine complications represent the majority of drivers resulting in 30 day readmission and measures to specifically reduce these by appropriate patient education and close postdischarge surveillance may represent a high impact opportunity for quality improvement efforts after RP. (via Semantic Scholar)
Source: Crossref
Added: December 7, 2020

2017 journal article

Development of selected reaction monitoring methods to systematically quantify kinase abundance and phosphorylation stoichiometry in human samples

Kinase Signaling Networks, 1636, 353–369.

By: K. Beck, N. Camp, M. Bereman, J. Bollinger, J. Egertson, M. MacCoss, A. Wolf-Yadlin

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Visceral and subcutaneous adipose tissue measurements associate with increased metabolic risk for NAFLD in pre-pubertal obese children

Hepatology, 66, 665A–665.

By: C. Moylan, A. Mavis, M. Bashir, D. Malik, E. Bozdogan, S. Buie, C. Hoyo, A. Diehl, S. Murphy, M. Abdelmalek

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

Human Molecular Genetics, 26(20), 4067–4085.

By: G. Sharp, L. Salas, C. Monnereau, C. Allard, P. Yousefi, T. Everson, J. Bohlin, Z. Xu ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease

PROTEOMICS, 17(17-18), 1700161.

author keywords: Amyotrophic lateral sclerosis; BMAA; Exposures; LC-MS; MS; Neurodegeneration
MeSH headings : Amino Acids, Diamino / toxicity; Amyotrophic Lateral Sclerosis / chemically induced; Amyotrophic Lateral Sclerosis / metabolism; Amyotrophic Lateral Sclerosis / pathology; Animals; Cell Line; Cyanobacteria Toxins; Diet / adverse effects; Excitatory Amino Acid Agonists / toxicity; Gene Expression Regulation / drug effects; Mice; Motor Neurons / metabolism; Motor Neurons / pathology; Neuroblastoma / metabolism; Neuroblastoma / pathology
TL;DR: Analysis of differentially regulated proteins reveals significant enrichment of pathways related to ER stress, protein ubiquitination, the unfolded protein response, and mitochondrial dysfunction, and the hypothesis that BMAA causes protein damage via misincorporation in place of L‐Serine is examined. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Maternal inflammatory diet and adverse pregnancy outcomes: Circulating cytokines and genomic imprinting as potential regulators?

EPIGENETICS, 12(8), 688–697.

By: L. McCullough*, E. Miller*, L. Calderwood*, N. Shivappa*, S. Steck*, M. Forman*, M. Mendez*, R. Maguire n ...

author keywords: Birthweight; cytokines; diet; DNA methylation; epidemiology; imprinted lgenes; inflammation
MeSH headings : Adolescent; Adult; Cytokines / blood; DNA Methylation; Diet; Female; Genomic Imprinting; Humans; Infant, Newborn; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Pregnancy Outcome / epidemiology; Pregnancy Outcome / genetics
TL;DR: This work replicates work by others on the association between maternal inflammatory diet and adverse pregnancy outcomes and provides the first empirical evidence supporting the inverse association between circulating cytokine concentrations and offspring methylation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Epigenetic regulation of AXL and risk of childhood asthma symptoms

Clinical Epigenetics, 9.

By: L. Gao, J. Millstein, K. Siegmund, L. Dubeau, R. Maguire, F. Gilliland, S. Murphy, C. Hoyo, C. Breton

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone program

Nature Communications, 8(1).

MeSH headings : Acetylation; Animals; DNA-Binding Proteins / metabolism; Heat Shock Transcription Factors / genetics; Heat Shock Transcription Factors / metabolism; Humans; Mice; Molecular Chaperones; Muscle, Skeletal / metabolism; Protein Processing, Post-Translational; Protein Refolding; TDP-43 Proteinopathies / metabolism
TL;DR: It is shown that acetylation of the protein triggers TDP-43 pathology in cultured cells and mouse skeletal muscle, which can be cleared through an HSF1-dependent chaperone mechanism that disaggregates the protein. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Is Body Mass Index the Best Adiposity Measure for Prostate Cancer Risk? Results From a Veterans Affairs Biopsy Cohort

UROLOGY, 105, 129–135.

By: L. Guerrios-Rivera*, L. Howard*, J. Frank*, A. De Hoedt*, D. Beverly*, D. Grant*, C. Hoyo n, S. Freedland*

MeSH headings : Adiposity; Aged; Body Mass Index; Case-Control Studies; Cohort Studies; Humans; Logistic Models; Male; Middle Aged; Neoplasm Grading; Prostatic Neoplasms / etiology; Prostatic Neoplasms / pathology; Risk Factors; Self Report; Veterans; Waist Circumference
TL;DR: This study supports the idea that higher adiposity is selectively associated with high-grade PC and reinforces the continued use of self-reported BMI as a measure of obesity in epidemiologic studies of PC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments

MOLECULAR & CELLULAR PROTEOMICS, 16(7), 1335–1347.

MeSH headings : Humans; Internet; Mass Spectrometry; Peptides / analysis; Proteomics / standards; Quality Control; Software
TL;DR: Evaluations on simulated data sets, and on data sets from the Clinical Proteomics Technology Assessment for Cancer consortium, demonstrated that these methods substantially improve the ability of real time monitoring, early detection and prevention of chromatographic and instrumental problems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Disparities in cervical cancer incidence and mortality: Can epigenetics contribute to eliminating disparities?

Cancer Disparities, 133, 129–156.

By: R. Maguire, A. Vidal, S. Murphy & C. Hoyo

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Cohort profile for the Nurture Observational Study examining associations of multiple caregivers on infant growth in the Southeastern USA

BMJ Open, 7(2).

By: S. Neelon, T. Ostbye, G. Bennett, R. Kravitz, S. Clancy, M. Stroo, E. Iversen, C. Hoyo

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight

BMC Public Health, 17.

By: Y. Luo, L. McCullough, J. Tzeng, T. Darrah, A. Vengosh, R. Maguire, A. Maity, C. Samuel-Hodge ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

The association between sexual function and prostate cancer risk in US veterans

ASIAN JOURNAL OF ANDROLOGY, 19(2), 191–195.

By: D. Zapata*, L. Howard*, J. Frank*, R. Simon*, C. Hoyo*, D. Grant n, S. Freedland*, A. Vidal*

author keywords: erectile dysfunction; prostate; prostate cancer risk; sexual function
MeSH headings : Age Factors; Aged; Biopsy; Body Mass Index; Diabetes Mellitus / epidemiology; Erectile Dysfunction / epidemiology; Heart Diseases / epidemiology; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasm Grading; Prostate-Specific Antigen / blood; Prostatic Neoplasms / blood; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / pathology; Risk Factors; Sexual Dysfunction, Physiological / epidemiology; Smoking / epidemiology; United States / epidemiology; Veterans / statistics & numerical data
TL;DR: Higher sexual function was associated with a decreased risk of overall and high-grade prostate cancer among men undergoing prostate biopsy, adjusting for multiple demographic and clinical characteristics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Temporal Trends in Exposure to Organophosphate Flame Retardants in the United States

ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 4(3), 112–118.

By: K. Hoffman*, C. Butt*, T. Webster*, E. Preston*, S. Hammel*, C. Makey*, A. Lorenzo*, E. Cooper* ...

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Mapping differential cellular protein response of mouse alveolar epithelial cells to multi-walled carbon nanotubes as a function of atomic layer deposition coating

NANOTOXICOLOGY, 11(3), 313–326.

author keywords: Carbon nanotube; label-free proteomics; pulmonary fibrosis; toxicoproteomics
MeSH headings : Aluminum Oxide / toxicity; Alveolar Epithelial Cells / chemistry; Alveolar Epithelial Cells / drug effects; Animals; Cells, Cultured; Mice; Nanotubes, Carbon / toxicity; Proteomics / methods; Pulmonary Fibrosis / etiology; Zinc Oxide / toxicity
TL;DR: It is demonstrated that specific types of metal oxide thin film coatings applied by ALD produce distinct cellular and biochemical responses related to lung inflammation and fibrosis compared to uncoated MWCNT exposure in vitro. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis

MOLECULAR CANCER RESEARCH, 15(2), 165–178.

By: D. Reaves*, K. Hoadley*, K. Fagan-Solis*, D. Jima n, M. Bereman n, L. Thorpe*, J. Hicks*, D. McDonald* ...

MeSH headings : Animals; Breast Neoplasms / genetics; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Carcinogenesis / genetics; Carcinogenesis / metabolism; Carcinogenesis / pathology; Cell Transformation, Neoplastic / genetics; Cell Transformation, Neoplastic / metabolism; Cell Transformation, Neoplastic / pathology; Female; Heterografts; Humans; Mice; Receptors, LDL / biosynthesis; Receptors, LDL / genetics; Receptors, LDL / metabolism
TL;DR: Results show that nuclear LSR alters gene expression and may promote aggressive cancer phenotypes through differential subcellular localization to alter cell signaling, bioenergetics, and gene expression. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

An Extended n-h bond, driven by a conserved second-order interaction, orients the flavin n5 orbital in cholesterol oxidase

Scientific Reports, 7.

By: E. Golden, L. Yu, F. Meilleur, M. Blakeley, A. Duff, A. Karton, A. Vrielink

Source: NC State University Libraries
Added: August 6, 2018

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