Microbiomes and Complex Microbial Communities

Works Published in 2013

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2013 journal article

RNAi silencing of a cytochrome P450 monoxygenase disrupts the ability of a filamentous fungus, Graphium sp., to grow on short-chain gaseous alkanes and ethers.

Biodegradation.

Michael Hyman

author keywords: Fungi; Alkane oxidation; Tetrahydrofuran; Cometabolism; Cytochrome P450
MeSH headings : Alkanes / metabolism; Biodegradation, Environmental; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System / classification; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Environmental Pollutants / metabolism; Ethers / metabolism; Gases; Gene Expression; Isoenzymes / antagonists & inhibitors; Isoenzymes / classification; Isoenzymes / genetics; Isoenzymes / metabolism; Oxidation-Reduction; Phylogeny; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; Saccharomycetales / enzymology; Saccharomycetales / genetics; Sequence Analysis, DNA
TL;DR: The results of this study suggest that GSPALK1 is the enzyme that catalyzes the initial oxidation of alkanes and ethers but is not involved in the later steps of alkane or ether metabolism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: April 28, 2020

2013 journal article

Oxidation of Cyclic Ethers by Alkane-Grown Mycobacterium vaccae JOB5

Remediation Journal, 23(4), 23–42.

By: R. Lan*, C. Smith n & M. Hyman n

TL;DR: The cometabolic oxidation of six cyclic ethers by alkane-grown Mycobacterium vaccae JOB5 is investigated and γ-Butyrolactone (γBL) is likely generated during THF oxidation through further oxidation of 2-hydroxytetrahydrofuran, which could have implications for approaches forcyclic ether biodegradation in the environment. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 5, 2019

2013 journal article

Understanding and exploiting feedback in synthetic biology

CHEMICAL ENGINEERING SCIENCE, 103, 79–90.

By: T. Afroz n & C. Beisel n

author keywords: Biological engineering; Feedback; Genetic circuit; Mathematical modeling; Process control; Synthetic biology
TL;DR: It is argued that biological feedback represents a powerful yet underutilized tool that can advance the construction of biological systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Biodegradation of gasoline ether oxygenates

Current Opinion in Biotechnology, 24(3), 443–450.

By: M. Hyman n

MeSH headings : Biodegradation, Environmental; Butanols / metabolism; Environmental Microbiology; Ether / chemistry; Ether / metabolism; Gasoline; Hydroxybutyrates / metabolism; Methyl Ethers / metabolism; Oxygen / chemistry; Oxygen / metabolism; Propylene Glycols / metabolism; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / metabolism
TL;DR: How microbiological and biochemical studies have guided, and have helped refine, molecular and stable isotope-based analytical approaches that are increasingly being used to detect and quantify biodegradation of these compounds in contaminated environments is illustrated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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