Works Published in 1997

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1997 journal article

Two molecular models of initial left-right asymmetry generation

Medical Hypotheses, 49(5), 429–435.

By: M. Levin* & N. Nascone*

MeSH headings : Animals; Body Patterning / genetics; Connexin 43 / physiology; Dyneins / physiology; Humans; Models, Molecular
TL;DR: Two models are presented, significantly supported by previous findings, which hypothesize that dynein asymmetrically localizes LR determinants in individual cells to establish cell-autonomous LR biasing, and asymmetric activity of Cx43 gap junctions within key cells sets up electric potentials in multicellular fields, thus establishing large-scale LR asymmetry. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

1997 journal article

Organizer Induction Determines Left–Right Asymmetry inXenopus

Developmental Biology, 189(1), 68–78.

By: N. Nascone* & M. Mercola*

MeSH headings : Animals; Embryonic Induction; Female; Heart / embryology; Xenopus laevis / embryology
TL;DR: It is shown that the induction of dorsal organizing centers in the embryo can orient left-right asymmetry, and this results indicate that LR asymmetry is locally oriented as a consequence of Wnt signaling through beta-catenin and Siamois. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

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