Works Published in 2019

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2019 journal article

Exome sequencing of family trios from the National Birth Defects Prevention Study: Tapping into a rich resource of genetic and environmental data

BIRTH DEFECTS RESEARCH, 111(20), 1618–1632.

author keywords: birth defects; gene-environment interaction; genetics; intestinal atresia; sequence analysis
MeSH headings : Congenital Abnormalities / genetics; Congenital Abnormalities / prevention & control; Family; Gene-Environment Interaction; Humans; Exome Sequencing
TL;DR: Successful sequencing of exomes from well-characterized NBDPS families indicated that this unique collection can be used to investigate the roles of genetic variation and gene-environment interaction effects in birth defect etiologies, providing a valuable resource for birth defect researchers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 12, 2019

2019 journal article

Vangl2 coordinates cell rearrangements during gut elongation


author keywords: Vangl2; endoderm; gut; Xenopus; morphogenesis; elongation
MeSH headings : Animals; Body Patterning; Cell Adhesion; Cell Movement; Cell Polarity; Endoderm / cytology; Intestines / anatomy & histology; Intestines / growth & development; Membrane Proteins / metabolism; Membrane Proteins / physiology; Morphogenesis; Xenopus Proteins / metabolism; Xenopus Proteins / physiology; Xenopus laevis / growth & development
TL;DR: The embryonic gut tube undergoes extensive lengthening to generate the surface area required for nutrient absorption across the digestive epithelium in Xenopus, a process that concomitantly opens the gut lumen and facilitates epithelial morphogenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 22, 2019

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