Works Published in 2020
Displaying all 4 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 review
The twists and turns of left-right asymmetric gut morphogenesis
[Review of ]. DEVELOPMENT, 147(19).
author keywords: Gut tube; Intestine; Laterality; Left-right asymmetry; Morphogenesis; Stomach
MeSH headings : Animals; Body Patterning / genetics; Body Patterning / physiology; Gastrointestinal Microbiome / genetics; Gastrointestinal Microbiome / physiology; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Humans; Morphogenesis / genetics; Morphogenesis / physiology; Signal Transduction / genetics; Signal Transduction / physiology
TL;DR:
New evidence is summarized challenging century-old ideas about the development of stomach and intestine laterality, challenging classical models of left-right asymmetric gut morphogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 16, 2020
2020 article
The people behind the papers - Caroline Johnson and Troy Ghashghaei
Johnson, C., & Ghashghaei, T. (2020, February). DEVELOPMENT, Vol. 147.
MeSH headings : Animals; Brain / embryology; Cell Proliferation; Developmental Biology / history; Developmental Biology / methods; History, 21st Century; Mice; Mitosis; Sp2 Transcription Factor / physiology
TL;DR:
This new paper in Development investigates the molecular control of mitosis in these two stages, using simultaneous labelling and gene knockout in clones in the developing mouse brain.
(via Semantic Scholar)
dev.biologists.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Sp2 regulates late neurogenic but not early expansive divisions of neural stem cells underlying population growth in the mouse cortex
DEVELOPMENT, 147(4).
author keywords: Corticogenesis; Mitosis; MADM; Neurogenesis; Sp2; Neural stem cell
MeSH headings : Alleles; Animals; Cell Differentiation; Cell Division; Cell Lineage; Cell Proliferation; Cerebral Cortex / embryology; Female; Gene Deletion; Genetic Markers; Male; Mice; Mice, Transgenic; Mitosis; Mutation; Neural Stem Cells / cytology; Phenotype; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / physiology
TL;DR:
It is found that loss of Sp2 in progenitors undergoing neurogenic divisions results in prolonged mitosis due to extension of early mitotic stages, and mechanistic differences between the early expansive and later neurogenic periods of cortical development are revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 20, 2020
2020 journal article
Ependyma-expressed CCN1 restricts the size of the neural stem cell pool in the adult ventricular-subventricular zone
EMBO JOURNAL, 39(5).
author keywords: CCN1; EGFR; ependymal cells; neural stem cells; niche
MeSH headings : Adult Stem Cells / physiology; Animals; Brain; Cysteine-Rich Protein 61 / genetics; Cysteine-Rich Protein 61 / metabolism; Ependyma / cytology; Ependyma / metabolism; ErbB Receptors / genetics; ErbB Receptors / metabolism; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / physiology; Signal Transduction
TL;DR:
It is shown that ependyma‐derived matricellular protein CCN1 (cellular communication network factor 1) negatively regulates niche capacity and NSC number in the adult ventricular–subventricular zone (V‐SVZ) of the adult brain to maintain the proper niche capacity of the V‐VZ.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: February 17, 2020
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