Works Published in 2011
Displaying all 9 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Permeability control in stimulus-responsive colloidosomes
Soft Matter, 7(5), 1948–1956.
Contributors: A. Miguel * & S. Behrens *
TL;DR:
A novel class of aqueous core colloidosomes that combine the benefit of low capsule permeability (good cargo retention) with the option of a stimulus-triggered fast release in a target environment is presented.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2011 journal article
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering”
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering.” The Journal of Physical Chemistry B, 115(36), 10778–10778.
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2011 journal article
An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells
Molecular Therapy, 19(4), 667–675.
MeSH headings : Animals; Cells, Cultured; Chromatography; Dependovirus / genetics; Female; Fluorescent Antibody Technique; Gene Transfer Techniques; Neural Stem Cells / virology; Polymerase Chain Reaction; Rats; Rats, Inbred F344
TL;DR:
This work applied directed evolution to create a "designer" AAV vector with enhanced delivery efficiency for neural stem cells (NSCs), and a novel AAV variant, carrying an insertion of a selected peptide sequence on the surface of the threefold spike within the heparin-binding site, emerged from this evolution.
(via Semantic Scholar)
doi.org (publisher)
Source: Crossref
Added: August 28, 2020
2011 journal article
Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells
STEM CELLS, 29(11), 1886–1897.
author keywords: Neural stem cells; Cellular mechanotransduction; Rho GTP-binding proteins; Adipose stem cells; Extracellular matrix; Elastic modulus
MeSH headings : Animals; Apoptosis / genetics; Apoptosis / physiology; Cell Differentiation / genetics; Cell Differentiation / physiology; Cell Proliferation; Cells, Cultured; Extracellular Matrix / metabolism; Female; Fluorescent Antibody Technique; Mechanotransduction, Cellular / genetics; Mechanotransduction, Cellular / physiology; Microscopy, Atomic Force; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / genetics; Neurogenesis / physiology; Rats; Rats, Inbred F344; cdc42 GTP-Binding Protein / genetics; cdc42 GTP-Binding Protein / metabolism; rho GTP-Binding Proteins / genetics; rho GTP-Binding Proteins / metabolism; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism
TL;DR:
These results establish Rho GTPase‐based mechanotransduction and cellular stiffness as biophysical regulators of NSC fate in vitro and RhoA as an important regulatory protein in the hippocampal stem cell niche.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Lipid resuscitation: a life-saving antidote for local anesthetic toxicity.
Current Pharmaceutical Biotechnology, 12(2), 313–319.
Contributors: S. Bern*, B. Akpa* , I. Kuo* & G. Weinberg
author keywords: Fat emulsion; heart arrest; intravenous; local anesthetics; overdose; resuscitation; toxicity
MeSH headings : Anesthesia, Conduction / adverse effects; Anesthetics, Local / administration & dosage; Anesthetics, Local / adverse effects; Anesthetics, Local / toxicity; Animals; Bupivacaine / administration & dosage; Bupivacaine / adverse effects; Bupivacaine / toxicity; Disease Models, Animal; Fat Emulsions, Intravenous / administration & dosage; Fat Emulsions, Intravenous / pharmacology; Fat Emulsions, Intravenous / therapeutic use; Female; Heart Arrest / chemically induced; Heart Arrest / drug therapy; Humans; Male; Rats
TL;DR:
Increased physician awareness and education, as well as optimized treatment protocols, will significantly reduce the rate of morbidity and mortality from local anesthetic toxicity.
(via Semantic Scholar)
Source: ORCID
Added: May 18, 2019
2011 journal article
Fractional Order Analysis of Sephadex Gel Structures: NMR Measurements Reflecting Anomalous Diffusion.
Communications in Nonlinear Science & Numerical Simulation, 16(12), 4581–4587.
Contributors: R. Magin *, B. Akpa* , T. Neuberger * & A. Webb *
author keywords: Diffusion; Exponential; Fractional derivative; Fractal; Magnetic resonance; Sephadex gel
TL;DR:
The fractional order decay model was fit to the diffusion-weighted signal attenuation for a range of b-values, and the parameters β, μ and D, were found to correlate with the porosity and tortuosity of the gel structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: May 18, 2019
2011 journal article
High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype
Genome Biology, 12(3), 219.
MeSH headings : Animals; Automation, Laboratory; Biotechnology; Caenorhabditis elegans / genetics; Caenorhabditis elegans / metabolism; Genetic Association Studies / methods; High-Throughput Screening Assays / methods; Mice; Phenotype; Plants / genetics; Plants / metabolism; RNA Interference
TL;DR:
High-throughput phenotyping approaches (phenomics) are being combined with genome-wide genetic screens to identify alterations in phenotype that result from gene inactivation in multicellular organisms.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 8, 2019
2011 journal article
Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy
Plant Physiology, 155(2), 735–750.
MeSH headings : Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Gene Expression Regulation, Plant; Gene Knockout Techniques; Inflorescence / genetics; Inflorescence / growth & development; Mutation; Phenotype; Phylogeny; Plant Roots / genetics; Plant Roots / growth & development; Plant Shoots / genetics; Plant Shoots / growth & development; RNA, Plant / genetics
TL;DR:
Arabidopsis mutants triply homozygous for knockout alleles in three Arabidopsis HAM orthologs exhibit loss of indeterminacy in both the shoot and root, which is fundamental to the generation of plant architecture and a central component of the plant life strategy.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 8, 2019
2011 journal article
Arabidopsis thaliana calcium-dependent lipid-binding protein (AtCLB): a novel repressor of abiotic stress response
JOURNAL OF EXPERIMENTAL BOTANY, 62(8), 2679–2689.
Contributors: K. De Silva, B. Laska, C. Brown*, H. Sederoff* & M. Khodakovskaya*
author keywords: Ca2+-sensing proteins; ceramide; increased tolerance to salt and drought stress; repressor of abiotic stress response; thalianol synthase gene
MeSH headings : Amino Acid Sequence; Arabidopsis / drug effects; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Ceramides / metabolism; DNA, Bacterial / genetics; DNA, Plant / metabolism; Droughts; Electrophoretic Mobility Shift Assay; Gene Expression Profiling; Gene Expression Regulation, Plant / drug effects; Genes, Plant / genetics; Gravitropism / drug effects; Gravitropism / genetics; Molecular Sequence Data; Mutation / genetics; Organ Specificity / drug effects; Organ Specificity / genetics; Plant Roots / drug effects; Plant Roots / metabolism; Promoter Regions, Genetic / genetics; Protein Binding / drug effects; Protein Transport / drug effects; Repressor Proteins / chemistry; Repressor Proteins / genetics; Repressor Proteins / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Salt Tolerance / drug effects; Salt Tolerance / genetics; Sodium Chloride / pharmacology; Stress, Physiological / drug effects; Stress, Physiological / genetics
TL;DR:
The role of the Atclb gene in negatively regulating responses to abiotic stress in Arabidopsis thaliana was identified and the loss of the ATCLb gene function confers an enhanced drought and salt tolerance and a modified gravitropic response in T-DNA insertion knockout mutant lines.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
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