Works Published in 2017

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Displaying all 13 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 chapter

Measuring Protein Movement, Oligomerization State, and Protein–Protein Interaction in Arabidopsis Roots Using Scanning Fluorescence Correlation Spectroscopy (Scanning FCS)

In W. Busch (Ed.), Plant Genomics (pp. 251–266).

Ed(s): W. Busch

author keywords: Scanning fluorescence correlation spectroscopy; Diffusion coefficient; Protein movement; Oligomerization state; Protein stoichiometry
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Plant Roots / metabolism; Spectrometry, Fluorescence / methods
TL;DR: The scanning FCS techniques of raster image correlation spectroscopy and pair correlation function (pCF) and number and brightness (N&B) and cross-correlation analyses can be used to determine oligomerization state and binding ratios of protein complexes. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 8, 2019

2017 chapter

Inferring Gene Regulatory Networks in the Arabidopsis Root Using a Dynamic Bayesian Network Approach

In K. Kaufmann & B. Mueller-Roeber (Eds.), Plant Gene Regulatory Networks (pp. 331–348).

By: M. Luis Balaguer n & R. Sozzani n

Ed(s): K. Kaufmann & B. Mueller-Roeber

author keywords: Gene regulatory network; Dynamic Bayesian network; Ordinary differential equation; Arabidopsis root
MeSH headings : Algorithms; Arabidopsis / genetics; Bayes Theorem; Computational Biology / methods; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Regulatory Networks; Plant Roots / genetics; Reproducibility of Results
TL;DR: The basic steps to implement a simple but computationally efficient algorithm to infer GRNs based on dynamic Bayesian networks (DBNs) are shown, and how to approximate DBN-based GRN models with continuous models is explained. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 8, 2019

2017 journal article

Dose-Duration Reciprocity for G protein activation: Modulation of kinase to substrate ratio alters cell signaling

PLOS ONE, 12(12).

MeSH headings : Arabidopsis / enzymology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis / metabolism; Arabidopsis Proteins / metabolism; GTP-Binding Proteins / metabolism; Genotype; Phosphorylation; Phosphotransferases / metabolism; Signal Transduction; Substrate Specificity
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Framework for gradual progression of cell ontogeny in the Arabidopsis root meristem

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(42), E8922–E8929.

author keywords: plant development; root meristem; Arabidopsis; transcriptional regulation
MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Flow Cytometry / methods; Gene Expression Regulation, Plant; Green Fluorescent Proteins / genetics; Meristem / cytology; Meristem / genetics; Plant Cells; Plant Roots / cytology; Plant Roots / genetics; Plant Roots / growth & development; Plants, Genetically Modified
TL;DR: It is proposed that cells in the Arabidopsis root meristem gradually transition from stem cell activity toward differentiation, by opposing gradients. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 article

Differential Effects of Sterols on Ion Channels: Stereospecific Binding vs Stereospecific Response

STEROL REGULATION OF ION CHANNELS, Vol. 80, pp. 25–50.

By: N. Barbera*, M. Ayee*, B. Akpa n & I. Levitan*

Contributors: N. Barbera*, M. Ayee*, B. Akpa n & I. Levitan*

MeSH headings : Cell Membrane / metabolism; Humans; Ion Channels / chemistry; Ion Channels / metabolism; Protein Binding; Stereoisomerism; Sterols / chemistry; Sterols / metabolism; Sterols / pharmacology; Substrate Specificity
TL;DR: Accumulating evidence suggests that the structural requirements of ion channel cholesterol-binding sites are lax, allowing chiral isomers of cholesterol to bind to the same site in a nonstereospecific way, but the ability of a sterol to confer a functional effect on the channel activity can still be stereospespecific. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Construction and setup of a bench-scale algal photosynthetic bioreactor with temperature, light, and pH monitoring for kinetic growth tests

Journal of Visualized Experiments, 2017(124).

By: A. Karam n, C. McMillan n, Y. Lai n, F. De Los Reyes n, H. Sederoff n, A. Grunden n, R. Ranjithan n, J. Levis n, J. Ducoste n

Contributors: A. Karam n, C. McMillan n, Y. Lai n, F. De Los Reyes n, H. Sederoff n, A. Grunden n, R. Ranjithan n, J. Levis n, J. Ducoste n

author keywords: Bioengineering; Issue 124; Photosynthetic bioreactors; microalgae; growth kinetics; biofuel; temperature; light; pH; automated monitoring
MeSH headings : Biofuels; Bioreactors / microbiology; Hydrogen-Ion Concentration; Kinetics; Light; Microalgae / growth & development; Models, Biological; Photosynthesis; Temperature
TL;DR: This protocol describes how to size and assemble a flat-plate, bench-scale PBR from acrylic and details how to configure a PBR with continuous pH, light, and temperature monitoring using a data acquisition and control unit, analog sensors, and open-source data acquisition software. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Predicting gene regulatory networks by combining spatial and temporal gene expression data in Arabidopsis root stem cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(36), E7632–E7640.

By: M. Balaguer n, A. Fisher n, N. Clark n, M. Fernandez-Espinosa*, B. Moller*, D. Weijers*, J. Lohmann*, C. Williams n ...

author keywords: root stem cell; root development; cell-type expression profile; gene regulatory network; modeling
MeSH headings : Algorithms; Arabidopsis / genetics; Bayes Theorem; Cluster Analysis; Computational Biology / methods; Gene Expression Profiling / methods; Gene Expression Regulation, Plant / genetics; Gene Regulatory Networks / genetics; Plant Roots / genetics; Stem Cells / metabolism; Transcription Factors / genetics; Transcriptome / genetics
TL;DR: A computational pipeline that uses gene expression datasets for inferring relationships among genes and predicting their importance and a gene regulatory network inference algorithm that combines clustering with dynamic Bayesian network inference that identified PERIANTHIA as an important molecular regulator of quiescent center function. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Genetic Architecture and Molecular Networks Underlying Leaf Thickness in Desert-Adapted Tomato Solanum pennellii

PLANT PHYSIOLOGY, 175(1), 376–391.

By: V. Coneva*, M. Frank*, M. Balaguer n, M. Li*, R. Sozzani n & D. Chitwood*

MeSH headings : Adaptation, Physiological / genetics; Bayes Theorem; Desert Climate; Gene Regulatory Networks; Organ Specificity; Phenotype; Plant Leaves / anatomy & histology; Plant Leaves / genetics; Plant Leaves / growth & development; Plant Leaves / physiology; Quantitative Trait Loci / genetics; Sequence Analysis, RNA; Solanum / anatomy & histology; Solanum / genetics; Solanum / growth & development; Solanum / physiology
TL;DR: A custom-built confocal profilometer was used to directly measure leaf thickness in a set of introgression lines (ILs) derived from the desert tomato Solanum pennellii and identified quantitative trait loci to establish a framework of genetic, anatomical, and molecular mechanisms that pattern leaf thicknessIn desert-adapted tomato. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(36), E7641–E7649.

By: R. Di Mambro, M. De Ruvo*, E. Pacifici, E. Salvi, R. Sozzani n, P. Benfey*, W. Busch*, O. Novak* ...

author keywords: plant hormones; cell differentiation; root meristem; computational modeling
MeSH headings : Arabidopsis / metabolism; Arabidopsis / physiology; Arabidopsis Proteins / metabolism; Biological Transport / physiology; Cell Differentiation / physiology; Cell Division / physiology; Cytokinins / metabolism; Gene Expression Regulation, Plant / physiology; Indoleacetic Acids / metabolism; Meristem / metabolism; Meristem / physiology; Plant Growth Regulators / metabolism; Plant Roots / metabolism; Plant Roots / physiology; Signal Transduction / physiology
TL;DR: Computational modeling and molecular genetics show that boundary formation is dependent on cytokinin’s control on auxin polar transport and degradation, and the regulation of both processes shapes the auxin profile in a well-defined auxin minimum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Using spectral and cumulative spectral entropy to classify anomalous diffusion in Sephadex (TM) gels

COMPUTERS & MATHEMATICS WITH APPLICATIONS, 73(5), 765–774.

author keywords: Anomalous diffusion; Fractional derivative; Cumulative spectral entropy; Continuous time random walk; Magnetic resonance imaging; Sephadex (TM) gel
TL;DR: This study investigates the relationship between the ADC of water and the complexity of a series of Sephadexgel beads and finds that both measures of entropy increase with the porosity and tortuosity of the gel in a manner consistent with fractional order diffusional dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Amino Acids Are an Ineffective Fertilizer for Dunaliella spp. Growth

FRONTIERS IN PLANT SCIENCE, 8.

By: C. Murphree n, J. Dums n, S. Jain n, C. Zhao*, D. Young n, N. Khoshnoodi*, A. Tikunov*, J. Macdonald* ...

Contributors: C. Murphree n, J. Dums n, S. Jain n, C. Zhao*, D. Young n, N. Khoshnoodi*, A. Tikunov*, J. Macdonald*, G. Pilot*, H. Sederoff n

author keywords: Dunaliella; nitrogen recycling; lipids; biofuel; amino acids; sustainability
TL;DR: It is found that only four amino acids (glutamine, histidine, cysteine, and tryptophan) rescue Dunaliella spp. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids

BIOPHYSICAL JOURNAL, 112(2), 325–338.

By: M. Ayee*, E. LeMaster*, T. Shentu*, D. Singh*, N. Barbera*, D. Soni*, C. Tiruppathi*, P. Subbaiah* ...

Contributors: M. Ayee*, E. LeMaster*, T. Shentu*, D. Singh*, N. Barbera*, D. Soni*, C. Tiruppathi*, P. Subbaiah* ...

MeSH headings : Animals; Biomechanical Phenomena / drug effects; Cattle; Cell Membrane / chemistry; Cell Membrane / drug effects; Cell Membrane / metabolism; Endothelial Cells / cytology; Lipid Bilayers / chemistry; Lipid Bilayers / metabolism; Mechanical Phenomena / drug effects; Molecular Conformation; Molecular Dynamics Simulation; Phospholipid Ethers / chemistry; Phospholipid Ethers / pharmacology
TL;DR: The results suggest that disruptions in membrane structure by oxidized phospholipids play a role in the regulation of overall endothelial cell stiffness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Accumulation of medium-chain, saturated fatty acyl moieties in seed oils of transgenic Camelina sativa

PLOS ONE, 12(2).

Contributors: Z. Hu n, Q. Wu n, J. Dalal n, N. Vasani n, H. Lopez n, H. Sederoff n, R. Qu n

MeSH headings : 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / deficiency; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase / genetics; Brassicaceae / genetics; Brassicaceae / metabolism; Plant Oils / metabolism; Plants, Genetically Modified; RNA Interference; Seeds / metabolism; Thiolester Hydrolases / genetics; Triglycerides / chemistry; Triglycerides / metabolism; Umbellularia / enzymology; Umbellularia / genetics
TL;DR: The results show that a California bay gene can be successfully used to modify the oil composition in camelina seed and present a new biological alternative for jet fuel production. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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