Works Published in 2022

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Displaying all 14 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 article

The double flower variant of yellowhorn is due to a LINE1 transposon-mediated insertion

Wang, H., Lu, Y., Zhang, T., Liu, Z., Cao, L., Chang, Q., … Zheng, Z. (2022, December 10). PLANT PHYSIOLOGY, Vol. 12.

MeSH headings : Phenotype; Sapindaceae / genetics; Magnoliopsida / genetics; DNA Transposable Elements / genetics; Flowers / genetics; Gene Expression Regulation, Plant
TL;DR: This work found a candidate C-class gene, AGAMOUS1 (XsAG1), through BSA sequencing and genetics analysis with a LONG INTERSPERSED NUCLEAR ELEMENTS 1 (LINE1) transposable element fragment inserted into its second intron that caused a loss-of-C-function and therefore the double-flower phenotype in yellowhorn. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023

2022 journal article

Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation

ISCIENCE, 25(11).

TL;DR: It is demonstrated that lifespan mutants can be identified by screening for accelerated protein aggregation through quantitative analysis of fluorescently-labeled aggregates in populations that do not require conditional sterilization or manual separation of parental and progeny populations. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: January 3, 2023

2022 journal article

DINOS: Data INspired Oligo Synthesis for DNA Data Storage

ACM JOURNAL ON EMERGING TECHNOLOGIES IN COMPUTING SYSTEMS, 18(3).

By: K. Volkel n, K. Tomek n, A. Keung n & J. Tuck n

author keywords: DNA information storage; DNA synthesis; DNA assembly algorithms
TL;DR: The approach offers greater density by up to 80% over a prior general purpose gene assembly technique, and in an analysis of synthesis costs, it is estimated that DINOS is as 105× cheaper than de novo synthesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 5, 2022

2022 journal article

High-throughput detection of T-DNA insertion sites for multiple transgenes in complex genomes

BMC GENOMICS, 23(1).

author keywords: Transgene; Insertion site; Polyploid; T-DNA; Sequencing
MeSH headings : DNA, Bacterial / genetics; Plant Breeding; Plants, Genetically Modified / genetics; Transgenes
TL;DR: A simple method to identify the sites of transgene insertions using T-DNA-specific primers and high-throughput sequencing that enables identification of multiple insertion sites in the T 1 generation of any crop transformed via Agrobacterium. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 17, 2022

2022 article

POPEYE intercellular localization mediates cell-specific iron deficiency responses

Muhammad, D. S., Clark, N. M., Haque, S., Williams, C. M., Sozzani, R., & Long, T. A. (2022, August 3). PLANT PHYSIOLOGY, Vol. 8.

MeSH headings : Iron Deficiencies; Arabidopsis Proteins / metabolism; Gene Expression Regulation, Plant; Basic Helix-Loop-Helix Transcription Factors / metabolism; Arabidopsis / metabolism; Iron / metabolism; Plant Roots / genetics; Plant Roots / metabolism
TL;DR: The findings indicate that PYE acts as a positive regulator of iron deficiency response by regulating iron bioavailability differentially across cells, which may trigger iron uptake from the surrounding rhizosphere and impact root energy metabolism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 29, 2022

2022 article

A roadmap towards equitable hiring to diversify biomedical engineering faculty

Cosgriff-Hernandez, E., Aguado, B. A., Akpa, B. S., Fleming, G. C., Moore, E., Porras, A. M., … Bowden, A. (2022, June 16). (Vol. 6). Vol. 6.

By: E. Cosgriff-Hernandez, B. Aguado, B. Akpa, G. Fleming, E. Moore, A. Porras, P. Boyle, D. Chan ...

Source: ORCID
Added: July 2, 2022

2022 journal article

Gene sdaB Is Involved in the Nematocidal Activity of Enterobacter ludwigii AA4 Against the Pine Wood Nematode Bursaphelenchus xylophilus

FRONTIERS IN MICROBIOLOGY, 5.

author keywords: sdaB; L-serine dehydratase; Enterobacter ludwigii; nematocidal activity; Bursaphelenchus xylophilus; pine wilt disease; methuosis
TL;DR: Enterobacter ludwigii AA4, isolated from the root of maize, has powerful nematocidal activity against B. xylophilus and has significant potential to serve as an agent for the biological control of pine wilt disease caused by B. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Source: NC State University Libraries
Added: June 7, 2022

2022 journal article

Human Pluripotent Stem Cell-Derived Medium Spiny Neuron-like Cells Exhibit Gene Desensitization

CELLS, 11(9).

By: R. Tam n & A. Keung n

author keywords: dopamine; gene desensitization; acute and chronic; RNA-seq; human embryonic stem cell; medium spiny neuron
MeSH headings : Dopamine; Humans; Neurites; Neurons / physiology; Pluripotent Stem Cells; Receptors, Dopamine
TL;DR: The dynamic responses of human stem cell-derived medium spiny neuron-like cells (hMSN- like cells) to dopamine are mapped and it is shown that these human neurons can reflect and capture cellular desensitization to chronic versus acute administration of dopamine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 23, 2022

2022 journal article

Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces

ISCIENCE, 25(5).

By: N. Barbera*, S. Granados*, C. Vanoye*, T. Abramova*, D. Kulbak*, S. Ahn*, A. George*, B. Akpa n, I. Levitan*

TL;DR: It was found that increasing membrane cholesterol reduced the likelihood of contact between specific regions of the cytoplasmic and transmembrane domains of the channel, most prominently at the subunit-subunit interfaces of the cytosolic domains. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: May 9, 2022

2022 journal article

RNA-Seq and Gene Regulatory Network Analyses Uncover Candidate Genes in the Early Defense to Two Hemibiotrophic Colletorichum spp. in Strawberry

FRONTIERS IN GENETICS, 12.

author keywords: Colletotrichum acutatum; Colletotrichum gloeosporioides; Fragaria x ananassa; rate-reducing resistance; gene regulatory network
TL;DR: Comparison transcriptome analyses and Gene regulatory network inference analysis revealed candidate transcription factors (TFs) such as GATA5 and MYB-10, and their downstream targets were upregulated in resistant interactions, which can provide valuable insights into transcriptional changes during resistant and susceptible interactions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 25, 2022

2022 article

Organic solar powered greenhouse performance optimization and global economic opportunity

Ravishankar, E., Booth, R. E., Hollingsworth, J. A., Ade, H., Sederoff, H., DeCarolis, J. F., & Brendan T. O'Connor. (2022, March 10). ENERGY & ENVIRONMENTAL SCIENCE, Vol. 15.

By: E. Ravishankar n, R. Booth n, J. Hollingsworth, H. Ade n, H. Sederoff n, J. DeCarolis n, . Brendan T. O'Connor

UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science
Added: March 19, 2022

2022 journal article

Field-grown soybean shows genotypic variation in physiological and seed composition responses to heat stress during seed development

ENVIRONMENTAL AND EXPERIMENTAL BOTANY, 195.

By: A. Ortiz*, I. De Smet*, R. Sozzani n & A. Locke n

author keywords: Photosynthesis; V-cmax; Respiration; Yield; Seed composition
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: March 14, 2022

2022 journal article

Modified Histone Peptides Linked to Magnetic Beads Reduce Binding Specificity

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(3).

By: J. Meanor n, A. Keung n & B. Rao n

author keywords: yeast surface display; histone post-translational modifications; affinity reagents; protein engineering; chromodomain; binder; reader; antibody; epigenome engineering; synthetic biology
MeSH headings : HEK293 Cells; Histone Code; Histones / metabolism; Humans; Jurkat Cells; K562 Cells; Protein Array Analysis; Protein Binding; Protein Engineering; Protein Processing, Post-Translational; Saccharomyces cerevisiae
TL;DR: Specific experimental conditions that affect binding specificities of post-translationally modified histones in classic protein engineering platforms are described and likely explain the relative difficulty with histone targets in these platforms. (via Semantic Scholar)
Source: Web Of Science
Added: February 21, 2022

2022 journal article

Gene regulatory networks for compatible versus incompatible grafts identify a role for SlWOX4 during junction formation

PLANT CELL, 34(1), 535–556.

MeSH headings : Capsicum / genetics; Capsicum / physiology; Gene Expression Regulation, Plant / physiology; Gene Regulatory Networks; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Solanum lycopersicum / genetics; Solanum lycopersicum / physiology; Plant Proteins / genetics; Plant Proteins / metabolism
TL;DR: A model system with Solanum lycopersicum ‘tomato’ and Capsicum annuum ‘pepper’ heterografting is developed, which expresses signs of anatomical junction failure within the first week of grafting, and SlWOX4 is the first gene to be functionally implicated in vegetable crop grafting. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 7, 2022

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