Works Published in 2021

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Displaying works 21 - 38 of 38 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 article

"FabNER": information extraction from manufacturing process science domain literature using named entity recognition

Kumar, A., & Starly, B. (2021, June 24). JOURNAL OF INTELLIGENT MANUFACTURING, Vol. 6.

By: A. Kumar n & B. Starly n

author keywords: NER; Technical language processing; TLP; Word2Vec; Topic modeling
TL;DR: This work presents a supervised machine learning approach to categorize unstructured text from 500K+ manufacturing science related scientific abstracts and labelling them under various manufacturing topic categories, using the developed NER model as a Technical Language Processing (TLP) workflow on manufacturing science documents. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 19, 2021

2021 article

Ex vivo evaluation of novel core tenorrhaphy patterns in dogs

Chiu, K. W., Duffy, D. J., Chang, Y.-J., Gaffney, L., & Fisher, M. B. (2021, July 6). VETERINARY SURGERY.

By: K. Chiu n, D. Duffy n, Y. Chang n, L. Gaffney n & M. Fisher n

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Random Allocation; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tensile Strength
TL;DR: Use of novel patterns ExDCrL, EmDCrl, and MTang improved resistance to loads and gap formation and were biomechanically superior compared to 3LP in healthy canine tendon repairs in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 12, 2021

2021 review

Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 173, 504–519.

author keywords: Cardiac fibrosis; Cardiac fibroblast; Myofibroblasts; Myocardial remodeling; Reprogramming; Drug delivery systems
MeSH headings : Animals; Drug Delivery Systems; Extracellular Matrix / metabolism; Extracellular Matrix / pathology; Fibrosis / metabolism; Fibrosis / pathology; Humans; Myocardium / metabolism; Myocardium / pathology; Myofibroblasts / metabolism; Myofibroblasts / pathology; Pharmaceutical Preparations / chemistry
TL;DR: This review will outline the progress of cardiac fibrosis and its contributions to the heart failure, and shed light on the role of myoFbs in the regulation of adverse remodeling. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 28, 2021

2021 review

Bioengineering Technologies for Cardiac Regenerative Medicine

[Review of ]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 9.

By: M. Chingale n, D. Zhu n, K. Cheng n & K. Huang

author keywords: bioengineering; cardiac repair; cell reprogramming; exosome; cardiac patch; targeting
TL;DR: Recent advancements in bioengineering and biotechnologies for cardiac regenerative medicine are discussed, including protein decoration, antibody modification, and platelet membranes have been used for targeting and precision medicine. (via Semantic Scholar)
Source: Web Of Science
Added: June 28, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li n, S. Hu n, D. Zhu n, K. Huang n, X. Mei n, B. Abad n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart Diseases / therapy; Humans; Injections
TL;DR: An in‐depth study of primary theories of cell loss, including low efficiency in cell injection, “washout” effects, and cell death, is undertaken and the literature from the past decade that focuses on cell transplantation to the heart using various cell delivery routes is organized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

2021 journal article

Processing variables of direct-write, near-field electrospinning impact size and morphology of gelatin fibers

BIOMEDICAL MATERIALS, 16(4).

By: Z. Davis*, A. Hussain* & M. Fisher*

author keywords: tissue engineering; gelatin; additive manufacturing; direct-write electrospinning; parametric control
MeSH headings : Biopolymers / chemistry; Electrochemical Techniques / methods; Gelatin / chemistry; Nanofibers / chemistry; Nanotechnology; Tissue Engineering; Tissue Scaffolds / chemistry
TL;DR: This system is capable of replicating the fibrous structure of musculoskeletal tissues with biologically relevant materials which will provide a durable platform for the analysis of single cell-fiber interactions to help better understand the impact scaffold materials and dimensions have on cell behavior. (via Semantic Scholar)
Source: Web Of Science
Added: May 24, 2021

2021 journal article

Biomechanical analysis of accessory tendon graft augmentation for primary gastrocnemius tendon reconstruction in dogs

VETERINARY SURGERY, 50(5), 1147–1156.

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases / surgery; Dogs; Hindlimb; Muscle, Skeletal / surgery; Orthopedic Procedures / veterinary; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength; Transplantation, Autologous / veterinary
TL;DR: Autologous ATG augmentation as an adjunct to primary GT repair increased yield, peak and failure forces by approximately 1.6% and 2.1% respectively, which justify studies to determine the effect of ATG on clinical function following graft harvest in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 24, 2021

2021 review

Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy

[Review of ]. BIOACTIVE MATERIALS, 6(7), 1957–1972.

By: S. Zhang n, D. Zhu n, X. Mei n, Z. Li n, J. Li n, M. Xie n, H. Xie, S. Wang*, K. Cheng n

author keywords: Stem cells; Primary ovarian insufficiency; Cell therapy; Biomaterials
TL;DR: A thorough understanding of the work already done can aid in the development of guidelines for future translational applications and clinical trials that aim to cure POI by using regenerative medicine and biomedical engineering strategies. (via Semantic Scholar)
Source: Web Of Science
Added: May 17, 2021

2021 journal article

Biomechanical evaluation of a novel barbed suture pattern with epitendinous suture augmentation in a canine flexor tendon model

VETERINARY SURGERY, 50(5), 1128–1136.

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases / surgery; Dogs; Forelimb; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tenotomy / veterinary; Tensile Strength
TL;DR: The NBSP repair tested here may be advantageous over monofilament suture repair as it uses a similar-sized barbed core suture but eliminates the requirement for knot tying. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 17, 2021

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

By: S. Hu n, Z. Li n, D. Shen n, D. Zhu n, K. Huang n, T. Su n, P. Dinh n, J. Cores n, K. Cheng n

MeSH headings : Animals; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Exosomes; Ischemia; Rats; Stents
TL;DR: It is shown that stents releasing exosomes derived from mesenchymal stem cells in the presence of reactive oxygen species enhance vascular healing in rats with renal ischaemia-reperfusion injury, promoting endothelial cell tube formation and proliferation, and impairing the migration of smooth muscle cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 26, 2021

2021 journal article

A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse

BIOACTIVE MATERIALS, 6(6), 1777–1788.

author keywords: Contraceptive; Hydrogel; Anti-viral; Libido; Erectile function
TL;DR: A novel TGN contraceptive gel consisting of three agents: tenofovir, gossypol acetate, and nitroglycerin (TGN) yielded a higher contraceptive success rate than that of the commercial contraceptive gel (Contragel®), and has the added benefits to prevent sexually transmitted diseases and improve male libido and erection function during sexual intercourse. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 19, 2021

2021 journal article

Recurrent neural networks with long term temporal dependencies in machine tool wear diagnosis and prognosis

SN APPLIED SCIENCES, 3(4).

By: J. Zhang n, Y. Zeng* & B. Starly n

author keywords: Recurrent neural networks; Long term temporal dependencies; Long short term memory; Tool wear; Remaining useful life
TL;DR: A recent deep learning method, including Long Short Term Memory (LSTM), which try to captures long-term dependencies than regular Recurrent Neural Network method for modeling sequential data, and also the mechanism to realize the online diagnosis and prognosis and remaining useful life (RUL) prediction with indirect measurement collected during the manufacturing process is proposed. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: April 19, 2021

2021 journal article

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

NATURE COMMUNICATIONS, 12(1).

MeSH headings : Animals; Cardiac Surgical Procedures; Cardiovascular Agents / administration & dosage; Cell Differentiation / physiology; Drug Delivery Systems / methods; Exosomes / metabolism; Extracellular Matrix / chemistry; Hydrogels / administration & dosage; Hydrogels / chemistry; Induced Pluripotent Stem Cells / transplantation; Male; Materials Testing; Mesenchymal Stem Cells / cytology; Mice; Minimally Invasive Surgical Procedures / methods; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Pericardium; Rats; Swine
TL;DR: In rodent models of myocardial infarction, it is demonstrated that intrapericardial injection is an effective and safe method to deliver hydrogels containing induced pluripotent stem cells-derived cardiac progenitor cells or mesenchymal stem Cells-derived exosomes. (via Semantic Scholar)
Source: Web Of Science
Added: April 12, 2021

2021 review

Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?

[Review of ]. CELLS, 10(3).

By: D. Zhu n & K. Cheng n

author keywords: stem cell; myocardial infarction; cardiovascular diseases; acellular therapy; exosomes; paracrine effects; biomedical engineering; biomaterials
MeSH headings : Cell- and Tissue-Based Therapy / methods; Heart Failure / pathology; Heart Failure / therapy; Humans; Myocardium / pathology; Myocytes, Cardiac / metabolism; Tissue Engineering / methods
TL;DR: Current therapeutic approaches for cardiac repair are summarized and discussed and a perspective on novel strategies that holding potential opportunities for future research and clinical translation are provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 12, 2021

2021 journal article

Self-Propelled and Near-Infrared-Phototaxic Photosynthetic Bacteria as Photothermal Agents for Hypoxia-Targeted Cancer Therapy

ACS NANO, 15(1), 1100–1110.

By: P. Zheng*, M. Fan*, H. Liu*, Y. Zhang*, X. Dai*, H. Li*, X. Zhou*, S. Hu n ...

MeSH headings : Drug Delivery Systems; Humans; Hyperthermia, Induced; Hypoxia; Neoplasms / drug therapy; Phototherapy
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: March 29, 2021

2021 journal article

Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

ADVANCED FUNCTIONAL MATERIALS, 31(15).

By: Z. Li n, D. Zhu n, Q. Hui*, J. Bi*, B. Yu*, Z. Huang*, S. Hu n, Z. Wang n ...

author keywords: bFGF; heart repair; intrapericardial delivery; pericardial cavity; ROS responsive hydrogels
TL;DR: A ROS‐sensitive cross‐linked poly(vinyl alcohol) (PVA) hydrogel is synthesized to deliver basic fibroblast growth factor (bFGF) for myocardial repair and protects cardiac function and reduces fibrosis in the post‐I/R heart, with enhanced angiomyogenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: February 22, 2021

2021 journal article

MVCNN plus plus : Computer-Aided Design Model Shape Classification and Retrieval Using Multi-View Convolutional Neural Networks

JOURNAL OF COMPUTING AND INFORMATION SCIENCE IN ENGINEERING, 21(1).

By: A. Angrish n, A. Bharadwaj n & B. Starly n

TL;DR: The proposed algorithm (MVCNN++) builds on the MVCNN algorithm with the addition of part dimension data, improving its efficacy for manufacturing part classification and yielding an improvement in classification accuracy of 5.8% over the original version. (via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 8, 2021

2021 review

Visualizing cancer extravasation: from mechanistic studies to drug development

[Review of ]. CANCER AND METASTASIS REVIEWS, 40(1), 71–88.

By: X. Cheng n & K. Cheng n

author keywords: Cancer metastasis; Cancer cell extravasation; Cancer models; Cancer therapies
MeSH headings : Drug Development; Humans; Neoplasm Metastasis; Neoplastic Cells, Circulating / pathology; Transendothelial and Transepithelial Migration
TL;DR: This review focuses on recent progress in cancer extravasation visualization techniques, including the development of both in vitro and in vivo cancerExtravasation models, that shed light on the underlying mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 24, 2020

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