Works Published in 2017
Displaying works 1 - 20 of 28 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Sensor Data and Information Fusion to Construct Digital-twins Virtual Machine Tools for Cyber-physical Manufacturing
Procedia Manufacturing, 10, 1031–1042.
author keywords: virtual machine tool; sensory data; data acquisition; information fusion; cyber-physical manufacturing; digital manufacturing
TL;DR:
Techniques are discussed for deploying sensors to capture machine-specific features, and analytical techniques of data and information fusion are presented for modeling and developing “digital-twins” virtual machine tools.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Streaming Machine Generated Data to Enable a Third-Party Ecosystem of Digital Manufacturing Apps
Procedia Manufacturing, 10, 1020–1030.
author keywords: Digital Manufacturing; MTCONNECT; PostgreSQL; Digital Manufacturing Commons (DMC)
TL;DR:
This proposed architecture enables an ecosystem of smart manufacturing applications to be built and deployed on the shop-floor through open-sourced software and hardware devices thereby reducing cost of manufacturing software development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
A flexible data schema and system architecture for the virtualization of manufacturing machines (VMM)
Journal of Manufacturing Systems, 45, 236–247.
author keywords: Cyber-physical manufacturing; Smart manufacturing; Digital twins; MongoDB; NoSQL
TL;DR:
This paper describes how streaming data can be stored in a scalable and flexible document schema based database such as MongoDB, a data store that makes up the virtual twin system that results in the virtualization of a machine resource to external factory manufacturing systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, ORCID
Added: September 13, 2019
2017 journal article
Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver
Cell Transplantation, 26(12), 1868–1877.
MeSH headings : Animals; Cell Differentiation / physiology; Cell Proliferation / physiology; Cell Survival / physiology; Hepatocytes / cytology; Hepatocytes / physiology; Liver / cytology; Liver Regeneration / physiology; Mice; Mice, Inbred BALB C; Stem Cells / cytology; Stem Cells / physiology
TL;DR:
The cell-based mechanisms of increased initial dwell time through magnetic targeting combined with high rate of proliferation in situ yield significant engraftment in the undamaged liver.
(via Semantic Scholar)
Source: Crossref
Added: July 28, 2019
2017 journal article
Animal Models in Tissue Engineering. Part II
Tissue Engineering Part C: Methods, 23(12), 827–828.
MeSH headings : Animals; Models, Biological; Tissue Engineering / methods; Tissue Engineering / trends
TL;DR:
Advances in areas such as 3D printing and bioreactor technologies now permit the in vitro development and testing of complex scaffold/cell composites, but in vivo testing remains critical for the critical efficacy and safety testing required for regulatory approval.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 27, 2019
2017 journal article
Improved Chondrogenic Potential and Proteomic Phenotype of Porcine Chondrocytes Grown in Optimized Culture Conditions
Cellular Reprogramming, 19(4), 232–244.
author keywords: chondrocytes; serum-free culture; low oxygen; pig; proteomics
MeSH headings : Animals; Cartilage / cytology; Cartilage / metabolism; Cell Culture Techniques / methods; Chondrocytes / cytology; Chondrocytes / metabolism; Chondrogenesis; Culture Media / chemistry; Extracellular Matrix Proteins / biosynthesis; Gene Expression Regulation; Swine
TL;DR:
Low-SFM culture conditions resulted in improved cell growth rates, reduced levels of de-differentiation during expansion, greater ability to re-differentiate into cartilage on induction, and an improved proteomic profile that resembles that of in vivo cartilage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 27, 2019
2017 journal article
Generation of a Stable Transgenic Swine Model Expressing a Porcine Histone 2B-eGFP Fusion Protein for Cell Tracking and Chromosome Dynamics Studies
PLOS ONE, 12(1), e0169242.
Ed(s): I. Polejaeva
MeSH headings : Animals; Cell Tracking / methods; Chromosomes, Mammalian / genetics; Chromosomes, Mammalian / metabolism; Female; Green Fluorescent Proteins / biosynthesis; Green Fluorescent Proteins / genetics; Histones / biosynthesis; Histones / genetics; Male; Organisms, Genetically Modified / genetics; Organisms, Genetically Modified / metabolism; Recombinant Fusion Proteins / biosynthesis; Recombinant Fusion Proteins / genetics; Swine / genetics; Swine / metabolism
TL;DR:
To the authors' knowledge this is the first viable transgenic pig model with chromatin-associated eGFP allowing both cell tracking and the study of chromatin dynamics in a large animal model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 27, 2019
2017 journal article
Macrophages' role in tissue disease and regeneration
Macrophages: Origin, Functions and Biointervention, 62, 245–271.
Source: NC State University Libraries
Added: August 6, 2018
2017 review
Rise of the Pigs: Utilization of the Porcine Model to Study Musculoskeletal Biomechanics and Tissue Engineering During Skeletal Growth
[Review of ]. TISSUE ENGINEERING PART C-METHODS, 23(11), 763–780.
author keywords: animal models; ligament and tendon; cartilage; bone; skeletal muscle
MeSH headings : Animals; Biomechanical Phenomena; Bone Development; Models, Animal; Musculoskeletal Physiological Phenomena; Regenerative Medicine; Sus scrofa; Tissue Engineering
TL;DR:
This review explores the publication history of the use of pig models in biomechanics and TERM discuss interspecies comparative studies, highlight studies on the effect of skeletal growth and other biological considerations in the porcine model, and present challenges and emerging opportunities for using this model to study functional TERM.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 conference paper
Investigating dielectric impedance spectroscopy as a non-destructive quality assessment tool for 3D cellular constructs
Proceedings of the ASME 12th International Manufacturing Science and Engineering Conference - 2017, vol 4.
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
Animal Models in Tissue Engineering. Part I
Tissue Engineering Part C: Methods, 23(11), 641–642.
author keywords: animal models; tissue engineering; regenerative medicine
MeSH headings : Animals; CRISPR-Cas Systems / genetics; Mice; Models, Animal; Rats; Sus scrofa; Tissue Engineering / methods; Translational Research, Biomedical
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Age-Dependent Subchondral Bone Remodeling and Cartilage Repair in a Minipig Defect Model
TISSUE ENGINEERING PART C-METHODS, 23(11), 745–753.
author keywords: subchondral bone; cartilage; microfracture; skeletal maturity
MeSH headings : Aging / physiology; Animals; Bone Remodeling; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / pathology; Cartilage, Articular / surgery; Collagen Type II / metabolism; Disease Models, Animal; Fluoroscopy; Immunohistochemistry; Male; Proteoglycans / metabolism; Swine; Swine, Miniature; Wound Healing; X-Ray Microtomography
TL;DR:
The significant impact of skeletal maturity on the propensity of subchondral bone to remodel as a result of chondral injury is shown to improve selection criteria for animal models for studying cartilage injury, repair, and treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis
STEM CELLS Translational Medicine, 6(10), 1905–1916.
author keywords: Fibrosis; Pulmonary; Syngeneic; Allogeneic; Stem cells
MeSH headings : Animals; Bleomycin / toxicity; Cells, Cultured; Female; Lung / cytology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / therapy; Rats; Rats, Wistar; Spheroids, Cellular / transplantation; Stem Cell Transplantation / adverse effects; Stem Cell Transplantation / methods; Transplantation, Homologous / adverse effects; Transplantation, Homologous / methods
TL;DR:
It is found that infusion of allogeneic LSCs reduces the progression of inflammation and fibrotic manifestation and preserves epithelial and endothelial health without eliciting significant immune rejection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Transplantation of human villous trophoblasts preserves cardiac function in mice with acute myocardial infarction
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 21(10), 2432–2440.
author keywords: Human villous trophoblasts; myocardial infarction; cell therapy; paracrine effects
MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Chorionic Villi / transplantation; Collagen; Drug Combinations; Heart / physiopathology; Human Umbilical Vein Endothelial Cells / physiology; Humans; Laminin; Male; Mice, Inbred C57BL; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / physiology; Neovascularization, Physiologic; Proteoglycans; Rats; Regeneration; Transplantation, Heterologous; Trophoblasts / transplantation
TL;DR:
It is shown that HVTs can promote tube formation of human umbilical vein endothelial cells (HUVECs) on Matrigel and enhance the resistance of neonatal rat cardiomyocytes (NRCMs) to oxidative stress in vitro and may be used as a source for cell therapy or a tool to study cell‐derived soluble factors for AMI treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Particle learning in online tool wear diagnosis and prognosis
JOURNAL OF MANUFACTURING PROCESSES, 28, 457–463.
author keywords: Particle learning; Tool wear; Intelligent manufacturing; Remaining useful life (RUL)
TL;DR:
A probabilistic method based on a Particle Learning (PL) approach by building a linear system transition function whose parameters are updated through online in-process observations of the machining process to avoid developing a complex closed form formulation for a specific tool wear model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Orientation changes in the cruciate ligaments of the knee during skeletal growth: A porcine model
Journal of Orthopaedic Research, 35(12), 2725–2732.
author keywords: anterior cruciate ligament; posterior cruciate ligament; adolescent; porcine; MRI
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Magnetic Resonance Imaging; Posterior Cruciate Ligament / diagnostic imaging; Posterior Cruciate Ligament / growth & development; Swine
TL;DR:
The age‐dependent properties of the ACL and PCL in the female pig mirrored results found in female human patients, suggesting that the porcine model may provide a pre‐clinical platform to study the cruciate ligaments during skeletal growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2017 article
Human Mesenchymal Stem Cells Expansion on Three-Dimensional (3D) Printed Poly-Styrene (PS) Scaffolds in a Perfusion Bioreactor
3RD CIRP CONFERENCE ON BIOMANUFACTURING, Vol. 65, pp. 115–120.
author keywords: Mesenchymal Stem Cells (MSCs); Cell Expansion Bioreactor; Poly-Styrene Scaffolds; Perfusion culture; 3D culture; Differentiation
TL;DR:
A novel approach of expanding Adipose derived hMSCs (human Mesenchymal Stem Cells) seeded on 3D printed Poly-Styrene scaffolds within a perfusion based cell expansion bioreactor resulted in comparable fold-expansion and viability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Heart Repair Using Nanogel-Encapsulated Human Cardiac Stem Cells in Mice and Pigs with Myocardial Infarction
ACS NANO, 11(10), 9738–9749.
author keywords: cardiac stem cells; nanogel; myocardial infarction; biomaterials; mouse model; pig model
MeSH headings : Acrylamides / chemistry; Acrylates / chemistry; Animals; Disease Models, Animal; Female; Humans; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Nanogels; Particle Size; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Surface Properties; Swine; Temperature
TL;DR:
In mice and pigs with acute MI, injection of encapsulated hCSCs preserves cardiac function and reduces scar sizes, whereas injection of hC SCs in saline has an adverse effect on heart healing, suggesting thermosensitive nanogels can be used as a stem cell carrier.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Biphasic Finite Element Modeling Reconciles Mechanical Properties of Tissue-Engineered Cartilage Constructs Across Testing Platforms
TISSUE ENGINEERING PART A, 23(13-14), 663–674.
author keywords: mechanical evaluation; mesenchymal stem cells; cartilage tissue engineering
MeSH headings : Animals; Cartilage / chemistry; Cartilage / cytology; Cartilage / metabolism; Cattle; Finite Element Analysis; Tissue Engineering
TL;DR:
Finite element (FE) models (using FEBio) of unconfined compression and indentation testing, modalities commonly used for in vitro grown samples, showed significant changes in material properties during the maturation of engineered cartilage tissue, capturing dynamic changes in functional tissue mechanics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies
Respiratory Research, 18(1).
author keywords: Pulmonary progenitor cells; Lung spheroid; Stem cell
MeSH headings : Adolescent; Aged; Animals; Biopsy; Bronchi / cytology; Bronchi / physiology; Cell Culture Techniques / methods; Female; Human Umbilical Vein Endothelial Cells / physiology; Humans; Infusions, Intravenous; Lung / cytology; Lung / physiology; Male; Mice; Mice, Nude; Middle Aged; Spheroids, Cellular / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology
TL;DR:
These cells could be utilized in long-term expansion of lung progenitor cells and as part of the development of cell-based therapies for the treatment of lung diseases such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
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