Works Published in 2000

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Displaying works 1 - 20 of 119 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2000 chapter

Table of Common Drugs: Approximate Dosages

In Kirk's Current Veterinary Therapy (13th ed., pp. 1241–1264). Philadelphia: W.B. Saunders Company.

Mark Papich

Ed(s): J. Bonagura & M. Papich

Source: NC State University Libraries
Added: July 1, 2022

2000 journal article

Surveying determinants of protein structure designability across different energy models and amino-acid alphabets: A consensus

The Journal of Chemical Physics.

Nick Buchler

TL;DR: A solvation model was demonstrated to give identical designability results to previous models, and was shown to be inherently related to thermodynamically relevant energetic measures of protein folding, such as the foldability F and energy gap Δ10. (via Semantic Scholar)
Source: ORCID
Added: February 16, 2022

2000 journal article

Gene targeting in domestic species: A new beginning

Transgenic Res, 9(4/5), 261–262.

MeSH headings : Animals; Animals, Domestic / genetics; Gene Targeting / methods; Gene Targeting / veterinary
TL;DR: The prospects and technical challenges for introducing targeted changes into the germline by this route, and the types of application for which this new technology will be used, are discussed. (via Semantic Scholar)
Source: Web Of Science
Added: October 29, 2021

2000 journal article

Differential Skills and Competencies Required of Faculty Teaching Distance Education Courses

International Journal of Educational Technology, 2(1).

By: R. Schoenfeld-Tacher & K. Persichitte

Source: NC State University Libraries
Added: April 24, 2021

2000 magazine article

An alternative method for induction of anesthesia in rabbits

Exotic DVM Magazine, 2, 5.

By: S. Foerster, M. McEwen & L. Posner

Source: NC State University Libraries
Added: August 28, 2019

2000 journal article

Three little pigs worth the huff and puff?

Nature Biotechnology, 18(11), 1144–1145.

By: M. Westhusin & J. Piedrahita*

MeSH headings : Animals; Cell Nucleus / metabolism; Cloning, Organism; Culture Techniques / methods; Ovum / metabolism; Swine; Transplantation, Heterologous
Source: Crossref
Added: July 27, 2019

2000 journal article

Evolutionary relationships between the amphibian, avian, and mammalian stomachs

Evolution and Development, 2(6), 348–359.

By: D. Smith*, R. Grasty*, N. Theodosiou*, C. Tabin* & N. Nascone-Yoder*

MeSH headings : Animals; Biological Evolution; Birds / anatomy & histology; Chick Embryo; Female; In Situ Hybridization; Mammals / anatomy & histology; Mice; Pregnancy; Stomach / anatomy & histology; Xenopus laevis / anatomy & histology
TL;DR: The global patterning of the gut is remarkably similar among the different vertebrate lineages, and the distinct compartments of gene expression that are found in the gut be necessary for the unique morphological specializations that distinguish the stomachs from terrestrial vertebrates. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

2000 chapter

Antimicrobial drugs

In S. J. Ettinger & E. C. Feldman (Eds.), Textbook of Veterinary Internal Medicine (5th ed., pp. 301–307). Philadelphia: W.B. Saunders Company.

By: M. Papich

Ed(s): S. Ettinger & E. Feldman

Source: NC State University Libraries
Added: April 13, 2019

2000 journal article

Pharmacologic Considerations for Opiate Analgesic and Nonsteroidal Anti-Inflammatory Drugs

Veterinary Clinics of North America: Small Animal Practice, 30(4), 815–837.

By: M. Papich n

MeSH headings : Analgesia / adverse effects; Analgesia / veterinary; Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Drug Interactions; Narcotics / adverse effects; Narcotics / pharmacology
TL;DR: The pharmacologic features of opioid analgesic drugs or nonsteroidal anti-inflammatory drugs are considered and a basis for important interactions, contraindications, and adverse effects is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 27, 2019

2000 journal article

The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13

GENE, 261(2), 235–242.

By: J. Yoder* & G. Litman*

author keywords: T51 radiation hybrid panel; LN54 radiation hybrid panel; hlx1; DBX; prkri; cd81
MeSH headings : Amino Acid Sequence; Animals; Antigens, CD / genetics; Carrier Proteins / genetics; Chromosome Mapping; Chromosomes, Human, Pair 11 / genetics; Conserved Sequence; Expressed Sequence Tags; Ferritins / genetics; Fusion Regulatory Protein-1; Genes / genetics; HSP40 Heat-Shock Proteins; Homeodomain Proteins / genetics; Humans; Membrane Proteins; Molecular Sequence Data; Protein Serine-Threonine Kinases / antagonists & inhibitors; Pyruvate Carboxylase / genetics; Radiation Hybrid Mapping; Repressor Proteins / genetics; Sequence Alignment; Sequence Homology, Amino Acid; Tetraspanin 28; Zebrafish / genetics
TL;DR: Six full-length zebrafish cDNAs, fth1, slc3a2, prkri, cd81, and pc, as well as one putative human gene, DBX were identified and their map positions ascertained, defining two regions of conserved synteny between linkage group 7 and 11q13. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2000 chapter

Immune-Type Diversity in the Absence of Somatic Rearrangement

In Current Topics in Microbiology and Immunology (Vol. 248, pp. 271–282).

By: J. Yoder* & G. Litman*

MeSH headings : Animals; Antibody Diversity; Biological Evolution; Fishes / genetics; Fishes / immunology; Gene Rearrangement; Genes, Immunoglobulin
TL;DR: The possibility that immune-type diversity is achieved in the absence of somatic rearrangement and that remnants of such systems could be operative in immune recognition in contemporary vertebrates is of extraordinary significance in terms of the authors' overall understanding of the relationships between adaptive and innate immune recognition. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2000 journal article

Pathologic findings and association of Mycobacterium bovis infection with the bovine NRAMP1 gene in cattle from herds with naturally occurring tuberculosis

AMERICAN JOURNAL OF VETERINARY RESEARCH, 61(9), 1140–1144.

By: R. Barthel, J. Piedrahita*, D. McMurray, J. Payeur, D. Baca, F. Guemes, V. Perumaalla, T. Ficht, J. Templeton, L. Adams

MeSH headings : Alleles; Animals; Carrier Proteins / genetics; Cation Transport Proteins; Cattle / genetics; Genetic Predisposition to Disease / genetics; Genotype; Immunity, Innate / genetics; Membrane Proteins / genetics; Mycobacterium bovis / isolation & purification; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Tuberculosis, Bovine / genetics; Tuberculosis, Bovine / pathology
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Isolation and genetic transformation of primordial germ cell (PGC)-derived cells from cattle, goats, rabbits and rats

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 13(5), 587–594.

By: C. Lee, K. Moore, N. Scales, M. Westhusin, G. Newton, K. Im, J. Piedrahita*

author keywords: primordial germ cell; embryonic germ cell; alkaline phosphatase staining; embryoid body; genetic transformation; green fluorescent protein
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Effects of protease inhibitors and antioxidants on in vitro survival of porcine primordial germ cells

BIOLOGY OF REPRODUCTION, 63(3), 887–897.

By: C. Lee*, R. Weaks*, G. Johnson*, F. Bazer* & J. Piedrahita*

author keywords: apoptosis; conceptus; cytokines; growth factors
MeSH headings : Acetylcysteine / administration & dosage; Acetylcysteine / pharmacology; Animals; Antioxidants / pharmacology; Apoptosis / drug effects; Cell Survival / drug effects; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Fetus / cytology; Germ Cells / drug effects; Germ Cells / physiology; In Situ Nick-End Labeling; Microscopy, Electron; Protease Inhibitors / pharmacology; Swine; alpha-Macroglobulins / administration & dosage; alpha-Macroglobulins / pharmacology
TL;DR: Results indicate that the addition of α2-macroglobulin and antioxidants can increase the number of PGCs in vitro by suppressing apoptosis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Effects of growth factors and feeder cells on porcine primordial germ cells in vitro

Cloning and Stem Cells, 2, 197–206.

MeSH headings : Alkaline Phosphatase / metabolism; Animals; Animals, Genetically Modified; COS Cells; Cell Culture Techniques; Cell Differentiation; Cell Membrane / metabolism; Chlorocebus aethiops; Culture Media / pharmacology; Embryo Culture Techniques; Embryo, Mammalian / cytology; Fibroblast Growth Factor 2 / metabolism; Fibroblasts / metabolism; Germ Cells / cytology; Germ Cells / metabolism; Growth Substances; Interleukin-6 / metabolism; Leukemia Inhibitory Factor; Lewis X Antigen / metabolism; Stem Cell Factor / metabolism; Stem Cells / cytology; Swine
TL;DR: A combination of growth factors and proper feeder cells are critical for the establishment of undifferentiated porcine EG cells. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

A rapid and sensitive reporter gene that uses green fluorescent protein expression to detect chemicals with estrogenic activity

TOXICOLOGICAL SCIENCES, 55(1), 69–77.

By: S. Miller*, D. Kennedy, J. Thomson, F. Han, R. Smith, N. Ing, J. Piedrahita*, D. Busbee

author keywords: cellular steroid receptors; endocrine disruption; xenobiotics; transfection; MCF7-ERE cells; estrogenic activity
MeSH headings : Cell Division / drug effects; Cell Line; Drug Evaluation, Preclinical; Estradiol / pharmacology; Estradiol Congeners / pharmacology; Eukaryotic Cells / drug effects; Genes, Reporter / drug effects; Genes, Reporter / genetics; Green Fluorescent Proteins; Humans; Luminescent Proteins / biosynthesis; Luminescent Proteins / genetics; Phosphoglycerate Kinase / metabolism; Plasmids / genetics; Receptors, Estrogen / drug effects; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Serum Albumin, Bovine / chemistry; Tamoxifen / analogs & derivatives; Tamoxifen / pharmacology; Transfection
TL;DR: The ERE-PGK-GFP reporter gene system is capable of rapid GFP expression in the presence of low concentrations of E2, and of quantifying estrogenicity of chemicals compared with a standard curve of the natural ligand, 17beta-estradiol. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2000 chapter

Air-liquid interface culture systems for exposure of differentiated cells to oxidant stress.

In Models and methods in cell signaling and gene expression applications to oxidative stress research. (pp. 15–30).

By: F. He, K. Adler, N. Akley, B. Fischer, N. Jiang, T. Krunkosky, L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Response of human airway epithelium in vitro to inflammatory mediators - Dependence on the state of cellular differentiation

Martin, L. D., Norford, D., Voynow, J., & Adler, K. B. (2000, May). CHEST, Vol. 117, pp. 267S–267S.

By: L. Martin n, D. Norford*, J. Voynow* & K. Adler n

TL;DR: The data suggest that the response of the airway epithelium to inflammatory mediators may be markedly different in undifferentiated vs fully differentiated cells, and these responses may play a role in further exacerbation of airway inflammation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 article

Myristoylated alanine-rich C-kinase substrate protein: A major intracellular regulatory molecule controlling secretion of mucin by human airway goblet cells.

Chest, Vol. 117, pp. 266S–267S.

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Mechanisms of human neutrophil elastase-induced mucin hypersecretion by human airway epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A155.

By: F. He, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

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