Works Published in 2013
Displaying works 1 - 20 of 127 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2013 journal article
Simultaneous Inactivation of the p16, p15 and p14 Genes Encoding Cyclin-Dependent Kinase Inhibitors in Canine T-Lymphoid Tumor Cells
Journal of Veterinary Medical Science, 75(6), 733–742.
Contributors: A. Fujiwara-Igarashi *, Y. Goto-Koshino *, H. Mochizuki* , S. Maeda *, Y. Fujino*, K. Ohno *, H. Tsujimoto *
MeSH headings : Amino Acid Sequence; Animals; Cell Line, Tumor; Cloning, Molecular; Cyclin-Dependent Kinase Inhibitor Proteins / genetics; Cyclin-Dependent Kinase Inhibitor Proteins / metabolism; DNA, Complementary / genetics; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Gene Expression Regulation, Neoplastic / physiology; Lymphocytes / metabolism; Lymphoma / metabolism; Lymphoma / veterinary; Molecular Sequence Data; Mutation; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
The p16, p15 and p14 genes are widely known as tumor suppressor genes in human medicine and wide-ranging deletions in the p15-p14-p16 genomic locus could be one of the molecular aberrations in canine lymphoid tumor cells.
(via Semantic Scholar)
www.jstage.jst.go.jp (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 23, 2023
2013 journal article
The Small GTPase Rsg1 is important for the cytoplasmic localization and axonemal dynamics of intraflagellar transport proteins.
Cilia.
TL;DR:
The data suggest that Rsg1 is a regulator of multiple aspects of ciliogenesis, including apical trafficking of basal bodies and the localization and dynamics intraflagellar transport proteins.
(via Semantic Scholar)
Source: ORCID
Added: March 23, 2022
2013 journal article
Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers.
Molecular Cancer Therapeutics.
MeSH headings : Breast Neoplasms / drug therapy; Breast Neoplasms / genetics; Breast Neoplasms / pathology; Catalase / genetics; Catalase / metabolism; DNA Breaks, Single-Stranded / drug effects; DNA Damage / drug effects; Female; Gene Expression Regulation, Neoplastic / drug effects; Humans; Hydrogen Peroxide / metabolism; NAD(P)H Dehydrogenase (Quinone) / genetics; NAD(P)H Dehydrogenase (Quinone) / metabolism; Naphthoquinones / administration & dosage; Necrosis / genetics; Necrosis / pathology; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases / genetics; Reactive Oxygen Species / metabolism
TL;DR:
Although PARP1 hyperactivation and NQO1 expression were major determinants of β-lapachone–induced lethality, alterations in catalase expression, including treatment with exogenous enzyme, caused marked cytoprotection, andCatalase is an important resistance factor and highlights H2O2 as an obligate ROS for cell death from this agent.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: June 25, 2021
2013 journal article
INTRACORONARY CARDIOSPHERE-DERIVED CELLS AFTER MYOCARDIAL INFARCTION: MAGNETIC RESONANCE IMAGING ANALYSIS OF REGENERATION AND DETERMINANTS OF EFFICACY IN THE FINAL 1-YEAR RESULTS OF THE CADUCEUS TRIAL
Journal of the American College of Cardiology, 61(10), E104.
TL;DR:
Cardiosphere-derived cells exert regenerative effects in post-MI patients with LV dysfunction in the CADUCEUS trial and correlates of efficacy are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: January 21, 2021
2013 chapter
Infectious diseases of the large intestine
In R. J. Washabau & M. J. Day (Eds.), Canine and Feline Gastroenterology (1st ed., pp. 745–757). St. Louis, MO: Elsevier Saunders.
Ed(s): R. Washabau & M. Day
Source: NC State University Libraries
Added: October 21, 2020
2013 journal article
Mechanically activated fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells
STEM CELLS, 31(11), 2528–2537.
author keywords: Src; Fyn; FAK; RhoA; Mesenchymal stem cells; Adipogenesis
MeSH headings : Adipogenesis / physiology; Cell Culture Techniques; Humans; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 2; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Multiprotein Complexes / genetics; Multiprotein Complexes / metabolism; Phosphorylation; Proto-Oncogene Proteins c-fyn / genetics; Proto-Oncogene Proteins c-fyn / metabolism; Signal Transduction; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Transfection; rhoA GTP-Binding Protein / metabolism
TL;DR:
Fyn expression in mdMSCs contributes to basal cytoskeletal architecture and, when associated with FAs, functions as a proximal mechanical effector for environmental signals that influence MSC lineage allocation.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2013 journal article
Investigating dielectric properties of different stages of syngeneic murine ovarian cancer cells
Biomicrofluidics, 7(1), 011809.
author keywords: bioelectric phenomena; biomedical measurement; biomembranes; bioMEMS; cancer; capacitance; cellular biophysics; electrophoresis; microfluidics
TL;DR:
Studying the electrical properties of MOSE cells provides important information as a first step to develop cancer-treatment techniques which could partially reverse the cytoskeleton disorganization of malignant cells to a morphology more similar to that of benign cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2013 journal article
Simultaneous electrokinetic flow and dielectrophoretic trapping using perpendicular static and dynamic electric fields
Microfluidics and Nanofluidics, 15(5), 599–609.
author keywords: Microfluidics; Numerical model; Electrokinetic micropump; Electro-osmosis; Contactless dielectrophoresis
Source: Crossref
Added: August 28, 2020
2013 journal article
Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices
ELECTROPHORESIS, 35(2-3), 352–361.
author keywords: Dielectrophoresis; Electrokinetic; Joule heating; Microchannel
MeSH headings : Electric Conductivity; Electrophoresis / instrumentation; Finite Element Analysis; Hot Temperature; Kinetics; Microfluidic Analytical Techniques / instrumentation; Microspheres
TL;DR:
It was observed that a temperature gradient is formed along the microchannel, which redistributes the conductivity of the suspending medium leading to an increase of the dielectrophoretic force toward the inlet of the channel while decreasing toward the outlet.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2013 journal article
Su1099 A Translational Porcine Model of Intestinal Stem Cells
Gastroenterology, 144(5), S-398.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2013 journal article
Expression of antisense of insulin-like growth factor-2 receptor RNA non-coding (AIRN) during early gestation in cattle
Animal Reproduction Science, 138(1-2), 64–73.
author keywords: Bovine; IGF2R; Antisense RNA; Embryo; Fetus
MeSH headings : Animals; Cattle / embryology; Embryo, Mammalian / metabolism; Female; Fertilization in Vitro / veterinary; Gene Expression Regulation, Developmental / genetics; Gene Expression Regulation, Developmental / physiology; Liver / metabolism; Male; Pregnancy; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Untranslated / genetics; Receptor, IGF Type 2 / genetics; Receptor, IGF Type 2 / metabolism; Reverse Transcriptase Polymerase Chain Reaction / veterinary
TL;DR:
BAIRN was not expressed in blastocyst-stage embryos, was expressed in an increasing proportion of embryos around the time of maternal recognition of pregnancy and was expressed following implantation, indicating relative levels of bAIRN in bovine fetal liver can be altered by method of embryo production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2013 conference paper
Sequestering of toxins for the reversal of drug toxicity: A coarse grained molecular dynamics study
Computational Molecular Science and Engineering Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 248. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911478625&partnerID=MN8TOARS
Contributors: M. Ayee & B. Akpa
Source: ORCID
Added: April 7, 2020
2013 conference paper
Positive inotropy - A likely mechanism for lipid reversal of local anesthetic toxicity
Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future, 535. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911417408&partnerID=MN8TOARS
Contributors: B. Akpa
Source: ORCID
Added: April 7, 2020
2013 journal article
Tu2027 The Chemotherapeutic Agent Doxorubicin Induces Contrasting Microbial Responses in the Jejunum and Distal Ileum That May Contribute to Differential Injury Patterns
Gastroenterology, 144(5), S-907-S-908.
Source: Crossref
Added: March 13, 2020
2013 journal article
Mo1824 Jejunal and Ileal Epithelium Demonstrate Differing Damage Responses to Doxorubicin Treatment
Gastroenterology, 144(5), S-672.
Source: Crossref
Added: March 13, 2020
2013 journal article
Tu2013 Characterization of Epithelial Cell Loss Due to Cryptosporidium Parvum Infection in a Non-Transformed Porcine Jejunal Enterocyte (IPEC-J2) Cell Line
Gastroenterology, 144(5), S-904-S-905.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 12, 2020
2013 journal article
Sa1762 Cysteine Proteases of the Enteric Trichomonad Tritrichomonas Foetus Mediate Adhesion to Intestinal Epithelial Cells and Enterocyte Apoptosis
Gastroenterology, 144(5), S-301.
TL;DR:
It is established that serine and cysteine proteases are the predominant mediators of feline TF proteolytic activity and identify the specific involvement of serine protease in TF survival and Cytopathogenicity to intestinal epithelial cells.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2020
2013 journal article
Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation
Journal of Allergy and Clinical Immunology, 132(6), 1388–1396.e3.
author keywords: Autosomal dominant hyper-IgE syndrome; Job syndrome; signal transducer and activator of transcription 3; mast cell; degranulation
MeSH headings : Adolescent; Adult; Aged; Animals; Cell Degranulation / genetics; Cells, Cultured; Child; Child, Preschool; Dermatitis, Atopic / genetics; Dermatitis, Atopic / immunology; Female; Food Hypersensitivity / epidemiology; Food Hypersensitivity / genetics; Food Hypersensitivity / immunology; Humans; Immunoglobulin E / metabolism; Incidence; Infant; Job Syndrome / epidemiology; Job Syndrome / genetics; Job Syndrome / immunology; Male; Mast Cells / immunology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mutation / genetics; STAT3 Transcription Factor / genetics; STAT3 Transcription Factor / physiology; Signal Transduction / genetics; Transgenes / genetics; Young Adult
TL;DR:
This study serves as an example for how mutations in specific atopic pathways can lead to discrete allergic phenotypes, encompassing increased risk of some phenotypes but a relative protection from others.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2013 journal article
Establishment of the Hermansky Pudlak Mastocyte (HPM) Cell Line Which Has the HPS1 16-Bp Duplication (c.1470_1486dup16)
Journal of Allergy and Clinical Immunology, 131(2), AB115.
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2013 journal article
Cats in Animal Shelters: Exploring the Common Perception that Black Cats Take Longer to Adopt
The Open Veterinary Science Journal, 7(1), 18–22.
TL;DR:
Secondary analysis of pre-existing data from two Colorado animal shelters was conducted to assess the impact of shelter cats' coat color on time required for adoption, indicating that black cats, regardless of age or sex, require the longest time to adopt.
(via Semantic Scholar)
Source: Crossref
Added: September 11, 2019
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